glyceraldehyde has been researched along with Diabetes Mellitus, Type 2 in 13 studies
Glyceraldehyde: An aldotriose containing the propionaldehyde structure with hydroxy groups at the 2- and 3-positions. It is involved in the formation of ADVANCED GLYCOSYLATION END PRODUCTS.
glyceraldehyde : An aldotriose comprising propanal having hydroxy groups at the 2- and 3-positions. It plays role in the formation of advanced glycation end-products (AGEs), a deleterious accompaniment to ageing.
aldose : Aldehydic parent sugars (polyhydroxy aldehydes H[CH(OH)]nC(=O)H, n >= 2) and their intramolecular hemiacetals.
Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.
| Excerpt | Relevance | Reference |
|---|---|---|
| "OP-lysine, a glycation product of lysine residues of proteins, has been reported to be formed with glyceraldehyde and glycolaldehyde as precursors in the lens, and has been suggested to play a role in senile cataracts." | 3.75 | Glyceraldehyde is present in rat lens and its level is increased in diabetes mellitus. ( Chen, AS; Miwa, I; Taguchi, T, 2009) |
| " The molecular mechanisms responsible for the glucose toxic effect on beta cell function involves disappearance of two important regulators of insulin promoter activity, PDX-1 and MafA." | 1.34 | Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes. ( Harmon, JS; Robertson, R; Zhang, T; Zhou, H, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (7.69) | 18.7374 |
| 1990's | 5 (38.46) | 18.2507 |
| 2000's | 4 (30.77) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 2 (15.38) | 2.80 |
| Authors | Studies |
|---|---|
| Martin-Morales, A | 1 |
| Arakawa, T | 1 |
| Sato, M | 1 |
| Matsumura, Y | 1 |
| Mano-Usui, F | 1 |
| Ikeda, K | 1 |
| Inagaki, N | 1 |
| Sato, K | 1 |
| Yasuda, Y | 1 |
| Aoki, H | 1 |
| Fujita, W | 1 |
| Fujibayashi, K | 1 |
| Wakasa, M | 1 |
| Kawai, Y | 1 |
| Nakanishi, H | 1 |
| Saito, K | 1 |
| Takeuchi, M | 3 |
| Kajinami, K | 1 |
| Miwa, I | 1 |
| Chen, AS | 1 |
| Taguchi, T | 1 |
| Verkleij, CJ | 1 |
| Nieuwdorp, M | 1 |
| Gerdes, VE | 1 |
| Mörgelin, M | 1 |
| Meijers, JC | 1 |
| Marx, PF | 1 |
| Tsunosue, M | 1 |
| Mashiko, N | 1 |
| Ohta, Y | 1 |
| Matsuo, Y | 1 |
| Ueda, K | 1 |
| Ninomiya, M | 1 |
| Tanaka, S | 1 |
| Hoshiko, M | 1 |
| Yoshiyama, Y | 1 |
| Ueda, S | 1 |
| Yamagishi, S | 1 |
| Robertson, R | 1 |
| Zhou, H | 1 |
| Zhang, T | 1 |
| Harmon, JS | 1 |
| Hughes, SJ | 1 |
| Suzuki, K | 1 |
| Goto, Y | 1 |
| Ohneda, M | 1 |
| Johnson, JH | 1 |
| Lee, YH | 1 |
| Nagasawa, Y | 1 |
| Unger, RH | 1 |
| Tsuura, Y | 2 |
| Ishida, H | 2 |
| Okamoto, Y | 2 |
| Kato, S | 2 |
| Horie, M | 2 |
| Ikeda, H | 2 |
| Seino, Y | 2 |
| Sakamoto, K | 1 |
| Okada, Y | 1 |
| Song, DK | 1 |
| Park, WK | 1 |
| Bae, JH | 1 |
| Park, MK | 1 |
| Kim, SJ | 1 |
| Ho, WK | 1 |
| Earm, YE | 1 |
| Makita, Z | 1 |
| Bucala, R | 1 |
| Suzuki, T | 1 |
| Koike, T | 1 |
| Kameda, Y | 1 |
| Grill, V | 1 |
| Rundfeldt, M | 1 |
13 other studies available for glyceraldehyde and Diabetes Mellitus, Type 2
| Article | Year |
|---|---|
Development of a Method for Quantitation of Glyceraldehyde in Various Body Compartments of Rodents and Humans.
Topics: Animals; Diabetes Mellitus, Type 2; Fasting; Glycation End Products, Advanced; Glyceraldehyde; Human | 2021 |
Glyceraldehyde-derived advanced glycation end-products are associated with left ventricular ejection fraction and brain natriuretic peptide in patients with diabetic adverse cardiac remodeling.
Topics: Diabetes Mellitus, Type 2; Glyceraldehyde; Heart Failure; Humans; Natriuretic Peptide, Brain; Stroke | 2022 |
Glyceraldehyde is present in rat lens and its level is increased in diabetes mellitus.
Topics: Aldehyde Reductase; Animals; Benzofurans; Blood Glucose; Cataract; Chromatography, High Pressure Liq | 2009 |
The effects of hyperglycaemia on thrombin-activatable fibrinolysis inhibitor.
Topics: Carboxypeptidase B2; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Dose-Response Relationship, | 2009 |
An alpha-glucosidase inhibitor, acarbose treatment decreases serum levels of glyceraldehyde-derived advanced glycation end products (AGEs) in patients with type 2 diabetes.
Topics: Acarbose; Aged; Diabetes Mellitus, Type 2; Enzyme Inhibitors; Female; Glycation End Products, Advanc | 2010 |
Chronic oxidative stress as a mechanism for glucose toxicity of the beta cell in type 2 diabetes.
Topics: Acetylcysteine; Animals; Antioxidants; Diabetes Mellitus, Type 2; Gene Expression; Glucose; Glutathi | 2007 |
The role of islet secretory function in the development of diabetes in the GK Wistar rat.
Topics: Aging; Animals; Arginine; Blood Glucose; Body Weight; Diabetes Mellitus, Type 2; Female; Glucose; Gl | 1994 |
Post-GLUT-2 defects in beta-cells of non-insulin-dependent diabetic obese rats.
Topics: Animals; Diabetes Mellitus, Type 2; Female; Glucose; Glucose Transporter Type 2; Glyceraldehyde; Ins | 1994 |
Reduced sensitivity of dihydroxyacetone on ATP-sensitive K+ channels of pancreatic beta cells in GK rats.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Diabetes Mellitus, Type 2; Dihydroxyacetone; Disease | 1994 |
Glucose sensitivity of ATP-sensitive K+ channels is impaired in beta-cells of the GK rat. A new genetic model of NIDDM.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Body Weight; Carbohydrate Metabolism, Inborn Errors; | 1993 |
Reduced dihydroxyacetone sensitivity and normal sensitivity to glyceraldehyde and oxidizing agent of ATP-sensitive K+ channels of pancreatic beta cells in NIDDM rats.
Topics: Adenosine Triphosphate; Animals; Diabetes Mellitus, Type 2; Dihydroxyacetone; Glucose; Glyceraldehyd | 1997 |
Immunological evidence that non-carboxymethyllysine advanced glycation end-products are produced from short chain sugars and dicarbonyl compounds in vivo.
Topics: Animals; Antibodies; Cattle; Chromatography, Affinity; Cross Reactions; Diabetes Mellitus, Type 2; E | 2000 |
Abnormalities of insulin responses after ambient and previous exposure to glucose in streptozocin-diabetic and dexamethasone-treated rats. Role of hyperglycemia and increased B-cell demands.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Blood Glucose; Dexamethasone; Diabetes Mellitus, Experimental; | 1986 |