glyburide has been researched along with Weight Loss in 8 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Weight Loss: Decrease in existing BODY WEIGHT.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this population of obese Hispanic patients with type 2 diabetes, sibutramine combined with glibenclamide therapy achieved weight loss for up to 12 months and was associated with better glycemic control than placebo." | 5.11 | Use of sibutramine in overweight adult hispanic patients with type 2 diabetes mellitus: a 12-month, randomized, double-blind, placebo-controlled clinical trial. ( Berber, A; Campos-Franco, E; Fanghänel, G; Martínez-Rivas, L; Sánchez-Reyes, L; Yamamoto, J, 2004) |
| " It is proposed that these effects are in part related to improved kidney function resulting in increased Hct and blood viscosity which increases vascular wall shear stress and NO bioavailability leading to a vasodilator effect." | 2.73 | Increased hematocrit and reduced blood pressure following control of glycemia in diabetes. ( Cabrales, P; Díaz, JS; Intaglietta, M; Negrete, AC; Salazar Vázquez, BY; Salazar Vázquez, MA; Venzor, VC, 2008) |
| " Its use is limited by a major side effect of cardiotoxicity." | 1.39 | Cardioprotective effects of nicorandil, a mitochondrial potassium channel opener against doxorubicin-induced cardiotoxicity in rats. ( Abdel-Raheem, IT; Abouzied, MM; Taye, A, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kumar, A | 1 |
| Sharma, S | 1 |
| Gupta, LP | 1 |
| Ahmad, P | 1 |
| Srivastava, SP | 1 |
| Rahuja, N | 1 |
| Tamrakar, AK | 1 |
| Srivastava, AK | 1 |
| Abdel-Raheem, IT | 1 |
| Taye, A | 1 |
| Abouzied, MM | 1 |
| Bhatia, A | 1 |
| Mishra, T | 1 |
| Sánchez-Reyes, L | 1 |
| Fanghänel, G | 1 |
| Yamamoto, J | 1 |
| Martínez-Rivas, L | 1 |
| Campos-Franco, E | 1 |
| Berber, A | 1 |
| Kar, DM | 1 |
| Maharana, L | 1 |
| Pattnaik, S | 1 |
| Dash, GK | 1 |
| Salazar Vázquez, BY | 1 |
| Salazar Vázquez, MA | 1 |
| Venzor, VC | 1 |
| Negrete, AC | 1 |
| Cabrales, P | 1 |
| Díaz, JS | 1 |
| Intaglietta, M | 1 |
| Peters, AL | 1 |
| Davidson, MB | 1 |
| Miossec, P | 1 |
| Lormeau, B | 1 |
| Valensi, P | 1 |
| Arthuis, F | 1 |
| Amouroux, J | 1 |
| Attali, JR | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Combination of Sulfonylureas and Insulin Glargine as Safety Net Outpatient Therapy for Unstable Diabetes and Impending Diabetic Ketoacidosis (DKA)[NCT00732524] | Phase 4 | 80 participants (Actual) | Interventional | 2004-09-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for glyburide and Weight Loss
| Article | Year |
|---|---|
Use of sibutramine in overweight adult hispanic patients with type 2 diabetes mellitus: a 12-month, randomized, double-blind, placebo-controlled clinical trial.
Topics: Adult; Aged; Appetite Depressants; Blood Glucose; Cyclobutanes; Diabetes Mellitus, Type 2; Double-Bl | 2004 |
Increased hematocrit and reduced blood pressure following control of glycemia in diabetes.
Topics: Blood Glucose; Blood Pressure; Creatinine; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Drug | 2008 |
6 other studies available for glyburide and Weight Loss
| Article | Year |
|---|---|
Synthesis of propiophenone derivatives as new class of antidiabetic agents reducing body weight in db/db mice.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Eating; Hypoglycemic Agents; Hypolipidemic | 2012 |
Cardioprotective effects of nicorandil, a mitochondrial potassium channel opener against doxorubicin-induced cardiotoxicity in rats.
Topics: Animals; Antihypertensive Agents; Antineoplastic Agents; Cardiovascular Diseases; Dose-Response Rela | 2013 |
Hypoglycemic activity of Ziziphus mauritiana aqueous ethanol seed extract in alloxan-induced diabetic mice.
Topics: Administration, Oral; Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Dose-Respons | 2010 |
Studies on hypoglycaemic activity of Solanum xanthocarpum Schrad. & Wendl. fruit extract in rats.
Topics: Alloxan; Animals; Blood Glucose; Cholesterol, VLDL; Diabetes Mellitus, Experimental; Diaphragm; Fatt | 2006 |
Maximal dose glyburide therapy in markedly symptomatic patients with type 2 diabetes: a new use for an old friend.
Topics: Adolescent; Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Female; Glyburide; Hum | 1996 |
Bone amyloidoma in a diabetic patient with morbid obesity.
Topics: Amyloidosis; Bone Diseases; Diabetes Complications; Diabetes Mellitus; Diabetes Mellitus, Type 2; Gl | 1999 |