glyburide has been researched along with Ventricular Dysfunction, Left in 7 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Ventricular Dysfunction, Left: A condition in which the LEFT VENTRICLE of the heart was functionally impaired. This condition usually leads to HEART FAILURE; MYOCARDIAL INFARCTION; and other cardiovascular complications. Diagnosis is made by measuring the diminished ejection fraction and a depressed level of motility of the left ventricular wall.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nineteen consecutive patients with type 2 diabetes and coronary artery disease entered the study." | 2.70 | Effects of treatment with sulfonylurea drugs or insulin on ischemia-induced myocardial dysfunction in type 2 diabetes. ( Avogaro, A; Bagolin, E; Negut, C; Palisi, M; Scognamiglio, R; Tiengo, A; Vigili de Kreutzenberg, S, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (71.43) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Giblett, JP | 1 |
| Axell, RG | 1 |
| White, PA | 1 |
| Clarke, SJ | 1 |
| McCormick, L | 1 |
| Read, PA | 1 |
| Reinhold, J | 1 |
| Brown, AJ | 1 |
| O'Sullivan, M | 1 |
| West, NE | 1 |
| Dutka, DP | 1 |
| Hoole, SP | 1 |
| Yousif, MH | 1 |
| Benter, IF | 1 |
| Roman, RJ | 1 |
| Ma, H | 1 |
| Huang, X | 1 |
| Li, Q | 1 |
| Guan, Y | 1 |
| Yuan, F | 1 |
| Zhang, Y | 1 |
| Lee, BH | 1 |
| Seo, HW | 1 |
| Yoo, SE | 1 |
| Lindhardt, TB | 1 |
| Gadsbøll, N | 1 |
| Kelbaek, H | 1 |
| Saunamäki, K | 1 |
| Madsen, JK | 1 |
| Clemmensen, P | 1 |
| Hesse, B | 1 |
| Haunsø, S | 1 |
| Shi, YX | 1 |
| Chen, Y | 1 |
| Zhu, YZ | 1 |
| Huang, GY | 1 |
| Moore, PK | 1 |
| Huang, SH | 1 |
| Yao, T | 1 |
| Zhu, YC | 1 |
| Scognamiglio, R | 1 |
| Avogaro, A | 1 |
| Vigili de Kreutzenberg, S | 1 |
| Negut, C | 1 |
| Palisi, M | 1 |
| Bagolin, E | 1 |
| Tiengo, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Investigation Into Cardioprotective Effect of Glucagon-like Peptide-1 and it's Mechanism of Action During Myocardial Ischaemia[NCT02128022] | Phase 1 | 32 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for glyburide and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Glucagon-like peptide-1 derived cardioprotection does not utilize a KATP-channel dependent pathway: mechanistic insights from human supply and demand ischemia studies.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Coronary Artery Disease; Coronary Vessels; Echocardiogra | 2016 |
Pharmacological modulation of the ATP sensitive potassium channels during repeated coronary occlusions: no effect on myocardial ischaemia or function.
Topics: Adenosine Triphosphate; Angina Pectoris; Anti-Arrhythmia Agents; Balloon Occlusion; Coronary Stenosi | 2004 |
Effects of treatment with sulfonylurea drugs or insulin on ischemia-induced myocardial dysfunction in type 2 diabetes.
Topics: Cardiomyopathies; Cross-Over Studies; Diabetes Mellitus, Type 2; Dipyridamole; Echocardiography, Str | 2002 |
4 other studies available for glyburide and Ventricular Dysfunction, Left
| Article | Year |
|---|---|
Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.
Topics: 8,11,14-Eicosatrienoic Acid; Amidines; Animals; Arachidonic Acid; Blood Glucose; Body Weight; Corona | 2009 |
ATP-dependent potassium channels and mitochondrial permeability transition pores play roles in the cardioprotection of theaflavin in young rat.
Topics: Animals; Atractyloside; Biflavonoids; Cardiotonic Agents; Catechin; Decanoic Acids; Glyburide; Heart | 2011 |
Cardioprotective effects of (2S,3R,4S)-N'-benzyl-N"-cyano-N-(3,4-dihydro-2-dimethoxymethyl-3-hydroxy-2-methyl-6-nitro-2H-benzopyran-4-yl)-guanidine (KR-31372) in rats and dogs.
Topics: Animals; Benzopyrans; Cardiovascular Agents; Coronary Circulation; Coronary Disease; Dogs; Dose-Resp | 2004 |
Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Cardiomegaly; Cardiotonic | 2007 |