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glyburide and Tachycardia, Ventricular

glyburide has been researched along with Tachycardia, Ventricular in 7 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Tachycardia, Ventricular: An abnormally rapid ventricular rhythm usually in excess of 150 beats per minute. It is generated within the ventricle below the BUNDLE OF HIS, either as autonomic impulse formation or reentrant impulse conduction. Depending on the etiology, onset of ventricular tachycardia can be paroxysmal (sudden) or nonparoxysmal, its wide QRS complexes can be uniform or polymorphic, and the ventricular beating may be independent of the atrial beating (AV dissociation).

Research Excerpts

ExcerptRelevanceReference
"The role of K(ATP) channels in the antiarrhythmic effect of Escherichia coli endotoxin-induced nitric oxide synthase (iNOS) was examined in an anesthetised rat model of myocardial ischemia and reperfusion arrhythmia by using glibenclamide (1 mg kg(-1)), nateglinide (10 mg kg(-1)) and repaglinide (0."3.74Glibenclamide attenuates the antiarrhythmic effect of endotoxin with a mechanism not involving K(ATP) channels. ( Erkent, U; Ertunc, M; Guc, MO; Ilhan, M; Iskit, AB; Onur, R, 2007)
"We assessed whether pravastatin attenuates cardiac sympathetic reinnervation after myocardial infarction through the activation of ATP-sensitive K(+) (K(ATP)) channels."3.74Effect of pravastatin on sympathetic reinnervation in postinfarcted rats. ( Chang, NC; Lee, TM; Lin, MS, 2007)
"More importantly, the incidence of ventricular tachycardia in the STZ-GLIB group was significantly higher than that in the STZ-VEH group (93% vs 54%, P < 0."1.32Long-term treatment with glibenclamide increases susceptibility of streptozotocin-induced diabetic rat heart to reperfusion-induced ventricular tachycardia. ( Iwao, T; Ooie, T; Saikawa, T; Sakata, T; Takahashi, N; Yoshimatsu, H, 2003)
"The incidence of ventricular tachycardia followed the same pattern."1.29Adenosine triphosphate-sensitive potassium channel blocking agent ameliorates, but the opening agent aggravates, ischemia/reperfusion-induced injury. Heart function studies in nonfibrillating isolated hearts. ( Hellegouarch, A; Tosaki, A, 1994)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (28.57)18.2507
2000's5 (71.43)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Takahashi, N1
Ooie, T1
Saikawa, T1
Iwao, T1
Yoshimatsu, H1
Sakata, T1
Iskit, AB1
Erkent, U1
Ertunc, M1
Guc, MO1
Ilhan, M1
Onur, R1
Lee, TM1
Lin, MS1
Chang, NC1
Tosaki, A1
Hellegouarch, A1
Workman, AJ1
MacKenzie, I1
Northover, BJ1
Miyashita, T1
Kubota, I1
Yamaki, M1
Watanabe, T1
Yamauchi, S1
Tomoike, H1
Liu, Y1
Downey, JM1

Other Studies

7 other studies available for glyburide and Tachycardia, Ventricular

ArticleYear
Long-term treatment with glibenclamide increases susceptibility of streptozotocin-induced diabetic rat heart to reperfusion-induced ventricular tachycardia.
    Experimental biology and medicine (Maywood, N.J.), 2003, Volume: 228, Issue:10

    Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Blood Pressure; Body Weight; Creatine Kinase; Diabetes

2003
Glibenclamide attenuates the antiarrhythmic effect of endotoxin with a mechanism not involving K(ATP) channels.
    Vascular pharmacology, 2007, Volume: 46, Issue:2

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Blood Pressure; Carbamates

2007
Effect of pravastatin on sympathetic reinnervation in postinfarcted rats.
    American journal of physiology. Heart and circulatory physiology, 2007, Volume: 293, Issue:6

    Topics: Animals; Blotting, Western; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; GA

2007
Adenosine triphosphate-sensitive potassium channel blocking agent ameliorates, but the opening agent aggravates, ischemia/reperfusion-induced injury. Heart function studies in nonfibrillating isolated hearts.
    Journal of the American College of Cardiology, 1994, Volume: 23, Issue:2

    Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Croma

1994
Do KATP channels open as a prominent and early feature during ischaemia in the Langendorff-perfused rat heart?
    Basic research in cardiology, 2000, Volume: 95, Issue:3

    Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Coronary Dise

2000
4-aminopyridine inhibits the occurrence of ventricular fibrillation but not ventricular tachycardia in the reperfused, P6olated rat heart.
    Japanese circulation journal, 2000, Volume: 64, Issue:8

    Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Glyburide; Heart; Heart Rate;

2000
Ischemic preconditioning protects against infarction in rat heart.
    The American journal of physiology, 1992, Volume: 263, Issue:4 Pt 2

    Topics: Adaptation, Physiological; Adenosine; Animals; Coronary Disease; Glyburide; Heart; In Vitro Techniqu

1992