glyburide has been researched along with Renal Insufficiency in 6 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Renal Insufficiency: Conditions in which the KIDNEYS perform below the normal level in the ability to remove wastes, concentrate URINE, and maintain ELECTROLYTE BALANCE; BLOOD PRESSURE; and CALCIUM metabolism. Renal insufficiency can be classified by the degree of kidney damage (as measured by the level of PROTEINURIA) and reduction in GLOMERULAR FILTRATION RATE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A one-time intervention in a risk reduction project decreased glyburide use over a 3-month period in elderly outpatients with renal insufficiency without compromising glucose control." | 8.87 | Intervention to decrease glyburide use in elderly patients with renal insufficiency. ( Aspinall, SL; Bartholomew, C; Boresi, J; Burlingame, M; Cox, S; Cunningham, FE; Frazer, J; Good, CB; Guterman, S; Jansen, D; Patino, M; Rivera-Miranda, G; Sellers, J; Stanard Steele, V; Stone, RA; Witt, L; Zhao, X, 2011) |
| "To (a) identify whether hemoglobin A1c remained equivalent in patients converted from glyburide to glipizide, (b) evaluate the prevalence of hypoglycemia during treatment with glyburide or glipizide, (c) compare change in glycemic control for renally impaired versus nonimpaired patients, and (d) analyze dosage conversion ratios selected by providers and measures of patient follow-up after conversion including time until A1c measurement and number of glipizide dose titrations." | 7.77 | Glycemic control and hypoglycemia in Veterans Health Administration patients converted from glyburide to glipizide. ( Cantrell, M; Egge, JA; Shaw, RF; Skoff, RA; Waterbury, NV, 2011) |
| "A one-time intervention in a risk reduction project decreased glyburide use over a 3-month period in elderly outpatients with renal insufficiency without compromising glucose control." | 4.87 | Intervention to decrease glyburide use in elderly patients with renal insufficiency. ( Aspinall, SL; Bartholomew, C; Boresi, J; Burlingame, M; Cox, S; Cunningham, FE; Frazer, J; Good, CB; Guterman, S; Jansen, D; Patino, M; Rivera-Miranda, G; Sellers, J; Stanard Steele, V; Stone, RA; Witt, L; Zhao, X, 2011) |
| "To (a) identify whether hemoglobin A1c remained equivalent in patients converted from glyburide to glipizide, (b) evaluate the prevalence of hypoglycemia during treatment with glyburide or glipizide, (c) compare change in glycemic control for renally impaired versus nonimpaired patients, and (d) analyze dosage conversion ratios selected by providers and measures of patient follow-up after conversion including time until A1c measurement and number of glipizide dose titrations." | 3.77 | Glycemic control and hypoglycemia in Veterans Health Administration patients converted from glyburide to glipizide. ( Cantrell, M; Egge, JA; Shaw, RF; Skoff, RA; Waterbury, NV, 2011) |
| "Patients with type 2 diabetes (n = 16,492) were randomized to saxagliptin or placebo and followed for a median of 2." | 2.82 | Predisposing Factors for Any and Major Hypoglycemia With Saxagliptin Versus Placebo and Overall: Analysis From the SAVOR-TIMI 53 Trial. ( Bhatt, DL; Braunwald, E; Cahn, A; Hirshberg, B; Im, K; Iqbal, N; Kanevsky, E; Leibowitz, G; Mosenzon, O; Raz, I; Rozenberg, A; Scirica, BM; Sjostrand, M; Stahre, C; Yanuv, I, 2016) |
| " We have demonstrated Gb to have a terminal elimination half-life of 15 h, and the main metabolites have a hypoglycaemic effect." | 2.69 | Pharmacokinetics of glibenclamide and its metabolites in diabetic patients with impaired renal function. ( Jönsson, A; Melander, A; Rydberg, T; Sterner, G, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 4 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cahn, A | 1 |
| Raz, I | 1 |
| Mosenzon, O | 1 |
| Leibowitz, G | 1 |
| Yanuv, I | 1 |
| Rozenberg, A | 1 |
| Iqbal, N | 1 |
| Hirshberg, B | 1 |
| Sjostrand, M | 1 |
| Stahre, C | 1 |
| Im, K | 1 |
| Kanevsky, E | 1 |
| Scirica, BM | 1 |
| Bhatt, DL | 1 |
| Braunwald, E | 1 |
| Holstein, A | 1 |
| Aspinall, SL | 1 |
| Zhao, X | 1 |
| Good, CB | 1 |
| Stone, RA | 1 |
| Boresi, J | 1 |
| Cox, S | 1 |
| Bartholomew, C | 1 |
| Jansen, D | 1 |
| Guterman, S | 1 |
| Patino, M | 1 |
| Rivera-Miranda, G | 1 |
| Burlingame, M | 1 |
| Frazer, J | 1 |
| Sellers, J | 1 |
| Stanard Steele, V | 1 |
| Witt, L | 1 |
| Cunningham, FE | 1 |
| Skoff, RA | 1 |
| Waterbury, NV | 1 |
| Shaw, RF | 1 |
| Egge, JA | 1 |
| Cantrell, M | 1 |
| Phillips, P | 1 |
| Braddon, J | 1 |
| Jönsson, A | 1 |
| Rydberg, T | 1 |
| Sterner, G | 1 |
| Melander, A | 1 |
2 reviews available for glyburide and Renal Insufficiency
| Article | Year |
|---|---|
Intervention to decrease glyburide use in elderly patients with renal insufficiency.
Topics: Age Factors; Aged; Antineoplastic Agents; Drug Substitution; Glyburide; Humans; Kidney; Metabolic Cl | 2011 |
Oral hypoglycaemics. When not to use what.
Topics: Acarbose; Acidosis, Lactic; Aged; Contraindications; Diabetes Mellitus, Type 2; Female; Glyburide; H | 2002 |
2 trials available for glyburide and Renal Insufficiency
| Article | Year |
|---|---|
Predisposing Factors for Any and Major Hypoglycemia With Saxagliptin Versus Placebo and Overall: Analysis From the SAVOR-TIMI 53 Trial.
Topics: Adamantane; Aged; Body Mass Index; Diabetes Mellitus, Type 2; Dipeptides; Female; Follow-Up Studies; | 2016 |
Pharmacokinetics of glibenclamide and its metabolites in diabetic patients with impaired renal function.
Topics: Adult; Aged; Diabetes Complications; Diabetes Mellitus; Female; Glyburide; Humans; Hypoglycemic Agen | 1998 |
2 other studies available for glyburide and Renal Insufficiency
| Article | Year |
|---|---|
Impact of renal impairment on the risk of severe hypoglycaemia associated with the use of insulin and glyburide.
Topics: Diabetes Mellitus; Glomerular Filtration Rate; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agents; | 2011 |
Glycemic control and hypoglycemia in Veterans Health Administration patients converted from glyburide to glipizide.
Topics: Aged; Blood Glucose; Creatinine; Diabetes Mellitus; Female; Glipizide; Glyburide; Glycated Hemoglobi | 2011 |