glyburide has been researched along with Pulmonary Fibrosis in 1 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Pulmonary Fibrosis: A process in which normal lung tissues are progressively replaced by FIBROBLASTS and COLLAGEN causing an irreversible loss of the ability to transfer oxygen into the bloodstream via PULMONARY ALVEOLI. Patients show progressive DYSPNEA finally resulting in death.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We previously reported that the endogenous cystathionine gamma-lyase (CSE)/hydrogen sulfide (H(2)S) pathway is implicated in the pathogenesis of bleomycin-induced pulmonary fibrosis in rats, but the exact cellular mechanisms are not well characterized." | 3.76 | Hydrogen sulfide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells. ( Fang, LP; Lin, Q; Liu, XM; Tang, CS, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, LP | 1 |
| Lin, Q | 1 |
| Tang, CS | 1 |
| Liu, XM | 1 |
1 other study available for glyburide and Pulmonary Fibrosis
| Article | Year |
|---|---|
Hydrogen sulfide attenuates epithelial-mesenchymal transition of human alveolar epithelial cells.
Topics: Benzodioxoles; Cadherins; Cell Line, Tumor; Cell Transdifferentiation; Cystathionine gamma-Lyase; Dr | 2010 |