glyburide has been researched along with Neuralgia in 5 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Neuralgia: Intense or aching pain that occurs along the course or distribution of a peripheral or cranial nerve.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present work evaluated the effects of the methanol extract of the bulbs of Dioscorea bulbifera in inflammatory and neuropathic models of pain and further investigated its possible mechanism of action." | 3.76 | Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation. ( Andrade, EL; Calixto, JB; Dutra, RC; Nguelefack, TB; Paszcuk, AF; Tapondjou, LA, 2010) |
| "Metformin was administered per os (p." | 1.51 | Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms. ( Augusto, PSA; Batista, CRA; Braga, AV; Coelho, MM; Costa, SOAM; Dutra, MMGB; Goulart, FA; Machado, RR; Melo, ISF; Morais, MI; Rodrigues, FF, 2019) |
| "Even ongoing inflammatory edema and mechanical allodynia were reduced by leflunomide." | 1.48 | Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1. ( Augusto, PSA; Brito, AMS; Coelho, MM; Costa, SOAM; Dutra, MGMB; Godin, AM; Goulart, FA; Ísis Morais, M; Machado, RR; Melo, ISF; Menezes, RR; Rodrigues, FF, 2018) |
| "Neuropathic pain is a serious chronic disorder caused by lesion or dysfunction in the nervous systems." | 1.36 | Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de ( Hayashi, S; Kato, A; Mizuno, K; Morita, A; Nakata, E; Ohashi, K; Yamamura, K, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 5 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hayashi, S | 1 |
| Nakata, E | 1 |
| Morita, A | 1 |
| Mizuno, K | 1 |
| Yamamura, K | 1 |
| Kato, A | 1 |
| Ohashi, K | 1 |
| Brito, AMS | 1 |
| Godin, AM | 1 |
| Augusto, PSA | 2 |
| Menezes, RR | 1 |
| Melo, ISF | 2 |
| Dutra, MGMB | 1 |
| Costa, SOAM | 2 |
| Goulart, FA | 2 |
| Rodrigues, FF | 2 |
| Ísis Morais, M | 1 |
| Machado, RR | 2 |
| Coelho, MM | 2 |
| Braga, AV | 1 |
| Morais, MI | 1 |
| Dutra, MMGB | 1 |
| Batista, CRA | 1 |
| Zoga, V | 1 |
| Kawano, T | 1 |
| Liang, MY | 1 |
| Bienengraeber, M | 1 |
| Weihrauch, D | 1 |
| McCallum, B | 1 |
| Gemes, G | 1 |
| Hogan, Q | 1 |
| Sarantopoulos, C | 1 |
| Nguelefack, TB | 1 |
| Dutra, RC | 1 |
| Paszcuk, AF | 1 |
| Andrade, EL | 1 |
| Tapondjou, LA | 1 |
| Calixto, JB | 1 |
5 other studies available for glyburide and Neuralgia
| Article | Year |
|---|---|
Discovery of {1-[4-(2-{hexahydropyrrolo[3,4-c]pyrrol-2(1H)-yl}-1H-benzimidazol-1-yl)piperidin-1-yl]cyclooctyl}methanol, systemically potent novel non-peptide agonist of nociceptin/orphanin FQ receptor as analgesic for the treatment of neuropathic pain: de
Topics: Analgesics; Animals; Benzimidazoles; Drug Design; Drug Evaluation, Preclinical; Humans; Microsomes, | 2010 |
Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1.
Topics: Animals; Chemokine CXCL1; Glyburide; Hyperalgesia; Isoxazoles; Leflunomide; Male; Mice; Naltrexone; | 2018 |
Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Glyburide; Hyperalgesia; Metformin; Mice; Naltr | 2019 |
KATP channel subunits in rat dorsal root ganglia: alterations by painful axotomy.
Topics: Animals; ATP-Binding Cassette Transporters; Axotomy; Calcitonin Gene-Related Peptide; Ganglia, Spina | 2010 |
Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation.
Topics: Animals; Cyclic GMP; Female; Freund's Adjuvant; Glyburide; Hyperalgesia; Inflammation; KATP Channels | 2010 |