Page last updated: 2024-10-28

glyburide and Neoplasms

glyburide has been researched along with Neoplasms in 14 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Treatment with glibenclamide could be associated with higher mortality for cardiovascular diseases and malignancies, in comparison with gliclazide."3.74Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality. ( Balzi, D; Barchielli, A; Buiatti, E; Lamanna, C; Mannucci, E; Marchionni, N; Masotti, G; Monami, M, 2007)
"Metformin, a first-line medication for type 2 diabetes mellitus, arouses growing concerns on its anti-cancer effect."2.55Enemies or weapons in hands: investigational anti-diabetic drug glibenclamide and cancer risk. ( Gao, R; Xu, W; Yang, T, 2017)
"It is pivotal and remains challenge for cancer precision treatment to identify the survival outcome interactions between genes, cells and drugs."1.62siGCD: a web server to explore survival interaction of genes, cells and drugs in human cancers. ( Cui, X; Han, L; Li, Y; Liu, Y; Song, B; Sun, W; Wang, H; Zhang, Y; Zhou, W, 2021)
" In secondary analyses, duration- and dose-response relationships were observed, with longer cumulative durations and cumulative doses associated with an increased risk of any cancer (>36 months: HR 1."1.42The Use of Glyburide Compared With Other Sulfonylureas and the Risk of Cancer in Patients With Type 2 Diabetes. ( Azoulay, L; Majdan, A; Tuccori, M; Wu, JW; Yin, H, 2015)
"Hyperglycaemia is a risk factor for cancer and some sulphonylureas have anti-oxidant properties."1.36Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry. ( Chan, JC; Chow, CC; Ko, GT; Kong, AP; Luk, AO; Ma, RC; Ng, VW; Ozaki, R; So, WY; Tong, PC; Yang, X; Yu, LW, 2010)
" At the same time about 1/3 of these serious adverse drug reactions (ADR) was found to have been reported to the ADR-register."1.27Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden. ( Westerholm, B; Wiholm, BE, 1984)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19901 (7.14)18.7374
1990's0 (0.00)18.2507
2000's4 (28.57)29.6817
2010's7 (50.00)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L2
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y2
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Zhou, Y1
Song, M1
Xie, D1
Yan, S1
Yu, S1
Xie, S1
Cai, M1
Li, H1
Shang, L1
Yuan, C1
Huang, M1
Li, J1
Xu, P1
Cui, X1
Han, L1
Liu, Y1
Sun, W1
Song, B1
Zhou, W1
Zhang, Y1
Wang, H1
Gao, R1
Yang, T1
Xu, W1
Tokunaga, T1
Ando, T1
Suzuki-Karasaki, M1
Ito, T1
Onoe-Takahashi, A1
Ochiai, T1
Soma, M1
Suzuki-Karasaki, Y1
Bo, S1
Castiglione, A1
Ghigo, E1
Gentile, L1
Durazzo, M1
Cavallo-Perin, P1
Ciccone, G1
Lamos, EL1
Stein, SA1
Davis, SN1
Tuccori, M1
Wu, JW1
Yin, H1
Majdan, A1
Azoulay, L1
Monami, M2
Lamanna, C2
Balzi, D2
Marchionni, N2
Mannucci, E2
Yang, X1
So, WY1
Ma, RC1
Yu, LW1
Ko, GT1
Kong, AP1
Ng, VW1
Luk, AO1
Ozaki, R1
Tong, PC1
Chow, CC1
Chan, JC1
Barchielli, A1
Masotti, G1
Buiatti, E1
Han, X1
Wang, F1
Yao, W1
Xing, H1
Weng, D1
Song, X1
Chen, G1
Xi, L1
Zhu, T1
Zhou, J1
Xu, G1
Wang, S1
Meng, L1
Iadecola, C1
Wang, G1
Ma, D1
Wiholm, BE1
Westerholm, B1

Reviews

3 reviews available for glyburide and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015
Enemies or weapons in hands: investigational anti-diabetic drug glibenclamide and cancer risk.
    Expert opinion on investigational drugs, 2017, Volume: 26, Issue:7

    Topics: Animals; ATP-Binding Cassette Transporters; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycem

2017
Sulfonylureas and meglitinides: historical and contemporary issues.
    Panminerva medica, 2013, Volume: 55, Issue:3

    Topics: Animals; Benzamides; Biomarkers; Blood Glucose; Diabetes Mellitus, Type 2; Glyburide; History, 20th

2013

Other Studies

11 other studies available for glyburide and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Structural Dynamics-Driven Discovery of Anticancer and Antimetastatic Effects of Diltiazem and Glibenclamide Targeting Urokinase Receptor.
    Journal of medicinal chemistry, 2023, 04-27, Volume: 66, Issue:8

    Topics: Diltiazem; Glyburide; Humans; Ligands; Neoplasms; Urokinase-Type Plasminogen Activator

2023
siGCD: a web server to explore survival interaction of genes, cells and drugs in human cancers.
    Briefings in bioinformatics, 2021, 09-02, Volume: 22, Issue:5

    Topics: Antineoplastic Agents; Biomarkers, Tumor; Drug Synergism; ErbB Receptors; Gene Expression Regulation

2021
Plasma-stimulated medium kills TRAIL-resistant human malignant cells by promoting caspase-independent cell death via membrane potential and calcium dynamics modulation.
    International journal of oncology, 2018, Volume: 52, Issue:3

    Topics: Calcium; Caspase 3; Caspase 7; Cell Death; Cell Line, Tumor; Culture Media; Dose-Response Relationsh

2018
Mortality outcomes of different sulphonylurea drugs: the results of a 14-year cohort study of type 2 diabetic patients.
    European journal of endocrinology, 2013, Volume: 169, Issue:1

    Topics: Adult; Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Confounding Factors, Epidemiol

2013
The Use of Glyburide Compared With Other Sulfonylureas and the Risk of Cancer in Patients With Type 2 Diabetes.
    Diabetes care, 2015, Volume: 38, Issue:11

    Topics: Aged; Cohort Studies; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Hypoglycemic Agents; Mal

2015
Sulphonylureas and cancer: a case-control study.
    Acta diabetologica, 2009, Volume: 46, Issue:4

    Topics: Aged; Case-Control Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Gliclazide; Glybur

2009
Use of sulphonylurea and cancer in type 2 diabetes-The Hong Kong Diabetes Registry.
    Diabetes research and clinical practice, 2010, Volume: 90, Issue:3

    Topics: Aged; Asian People; Cohort Studies; Diabetes Mellitus, Type 2; Female; Gliclazide; Glipizide; Glybur

2010
Are sulphonylureas all the same? A cohort study on cardiovascular and cancer-related mortality.
    Diabetes/metabolism research and reviews, 2007, Volume: 23, Issue:6

    Topics: Aged; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus, Type 2; Female; Follow-Up Studies;

2007
Heat shock proteins and p53 play a critical role in K+ channel-mediated tumor cell proliferation and apoptosis.
    Apoptosis : an international journal on programmed cell death, 2007, Volume: 12, Issue:10

    Topics: 4-Aminopyridine; Alkaloids; Apoptosis; bcl-2-Associated X Protein; Benzylisoquinolines; Calcium Chan

2007
Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden.
    Acta medica Scandinavica. Supplementum, 1984, Volume: 683

    Topics: Acidosis; Aged; Anti-Infective Agents, Urinary; Biguanides; Congenital Abnormalities; Contraceptives

1984