glyburide has been researched along with Muscle Relaxation in 195 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The effects of NG-monomethyl-L-arginine, tetrodotoxin and glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial coronary artery rings of the rabbit." | 7.69 | Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. ( Collins, P; Jiang, C, 1994) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 5.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "To investigate the functional presence of adenosine triphosphate (ATP)-sensitive potassium (K+) channels (K(ATP)) in penile resistance arteries by evaluating the relaxant effects of the selective K(ATP) channel openers, cromakalim and levcromakalim, and also the involvement of K(ATP) channels in the relaxation of two drugs currently used in the treatment of erectile dysfunction (ie, prostaglandin E1 [PGE1] and sildenafil)." | 3.72 | Role of ATP-sensitive K+ channels in relaxation of penile resistance arteries. ( Benedito, S; García, P; García-Sacristán, A; Hernández, M; Prieto, D; Recio, P; Rivera de los Arcos, L; Ruiz Rubio, JL, 2004) |
| " Spontaneous detrusor muscle contractions were unaffected by glibenclamide (K(ATP) channel blocker) but were reduced when pinacidil (K(ATP) channel opener) concentrations exceeded 10(-5) M." | 3.70 | K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle. ( Elliott, RA; Hudman, D; Norman, RI, 2000) |
| ", cromakalim, pinacidil) are potent relaxants of smooth muscle, their utility for treating myocardial ischemia may be limited by hypotension." | 3.69 | Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448. ( Atwal, KS; D'Alonzo, AJ; Grover, GJ; McCullough, JR; Sargent, CA, 1995) |
| " The effects of NG-monomethyl-L-arginine, tetrodotoxin and glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial coronary artery rings of the rabbit." | 3.69 | Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. ( Collins, P; Jiang, C, 1994) |
| "3,5-Di-substituted phenylcyanoguanidine derivatives with halogen, cyano and/or nitro groups at the 3- and 5-positions of the benzene ring exhibited very strong smooth muscle relaxation activity in vitro, as compared to pinacidil." | 3.69 | Synthesis and structure-activity relationships of novel phenylcyanoguanidine derivatives as potassium channel openers. ( Goto, K; Ikeda, S; Morita, T; Nishimura, N; Sukamoto, T; Yoshiizumi, K; Yoshino, K, 1996) |
| " The drugs antagonized the relaxant response to the K+ channel opener cromakalim (order of effectiveness: glibenclamide > glipizide > glibornuride) and at concentrations of 1-1000 microM produced airway smooth muscle relaxation (order of potency: glibenclamide > glipizide = glibornuride)." | 3.68 | Effects of antidiabetic sulphonylureas, cromakalim and their interaction in guinea-pig isolated tracheal smooth muscle. ( Nielsen-Kudsk, JE; Thirstrup, S, 1993) |
| "Nicorandil may also activate Maxi K(+) channels, possibly through the NO-cGMP pathway, and the interaction of K ATP channels and Maxi K(+) channels may affect the relaxant effect of nicorandilin bovine tracheal smooth muscle." | 1.38 | The relaxant action of nicorandil in bovine tracheal smooth muscle. ( Ishii, K; Moriuchi, H; Nakahara, T; Sakamoto, K; Yunoki, M, 2012) |
| " Dose-response study on the prostate strip was performed by cumulative administration of loperamide 0." | 1.37 | Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors. ( Chen, IH; Cheng, JT; Tong, YC; Yu, BC, 2011) |
| " Levcromakalim produced concentration-dependent inhibitory effect on myometrial spontaneity and relaxant effect and the dose-response curve (DRC) was shifted towards right in the presence of glybenclamaide." | 1.36 | Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis). ( Choudhury, S; Garg, SK; Mishra, SK; Singh, TU, 2010) |
| "3 x 10(-3) mol/L) produced a significant rightward shift in the phenylephrine dose-response curve, but had no effects on the potassium chloride-induced contraction." | 1.35 | Relaxant effects of matrine on aortic smooth muscles of guinea pigs. ( Dai, GD; Fu, XY; Yan, L; Zheng, J; Zheng, P; Zhou, R; Zhou, X, 2009) |
| "The effects of tramadol (racemic, R(-) and S(+): 10(-6), 10(-5), 5 x 10(-5) M), and glibenclamide on the levcromakalim dose-response curve were assessed in aortic rings that had been pre-contracted with phenylephrine." | 1.34 | Inhibitory effect of tramadol on vasorelaxation mediated by ATP-sensitive K+ channels in rat aorta. ( Chang, KC; Cho, HC; Chung, YK; Lee, HK; Lee, JW; Park, KE; Shin, IW; Sohn, JT, 2007) |
| " Incubation with CGRP8-37 (10(-6) M) specifically during the 90-minute desensitization period with nitroglycerin resulted in even greater impairment in the response to nitroglycerin in tolerant rings, even though the calcitonin gene-related peptide antagonist had been washed out before completion of the nitroglycerin dose-response curve." | 1.33 | Nitroglycerin-induced release of calcitonin gene-related peptide from sensory nerves attenuates the development of nitrate tolerance. ( Ghatta, S; O'Rourke, ST, 2006) |
| "Bimakalim was more potent (pIC50=7." | 1.31 | Atypical effect of minoxidil sulphate on guinea pig airways. ( Buchheit, KH; Hofmann, A; Manley, P; Pfannkuche, HJ; Quast, U, 2000) |
| "Sevoflurane responses were repeated at concentrations with no effect on spontaneous contractility of TEA, a Ca(2+)-activated K(+) channel blocker, and glibenclamide, an adenosine triphosphate-sensitive K(+) channel blocker, in myometrial strips." | 1.31 | The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium. ( Bagcivan, I; Gürsoy, S; Kafali, H; Karadas, B; Kaya, T; Sarioglu, Y, 2002) |
| "5 microM) had no significant effect on relaxation dose-response curves (DRCs) to ACh, NTG or NO." | 1.29 | Role of calcium-activated K+ channels in vasodilation induced by nitroglycerine, acetylcholine and nitric oxide. ( Khan, SA; Mathews, WR; Meisheri, KD, 1993) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 1.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "1 ml), and dose-response curves to levcromakalim (a KATP channel opener) or isoproterenol were constructed." | 1.29 | Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro. ( Croxton, TL; Fernandes, LB; Hirshman, CA; Lindeman, KS, 1994) |
| "2." | 1.28 | One way cross tolerance between cromakalim and salbutamol in the uterus of the rat in vivo. ( Downing, SJ; Hollingsworth, M, 1992) |
| "Cromakalim was less effective against the 25." | 1.28 | Effects of cromakalim on the contraction and the membrane potential of the circular smooth muscle of guinea-pig stomach. ( Asano, M; Ito, K; Kanno, T; Masuzawa-Ito, K; Ohashi, H; Suzuki, H; Suzuki, K; Takewaki, T, 1992) |
| "Fraxinellone and verapamil were more potent and effective in producing relaxation in 60 mmol/l than in 15 mmol/l K(+)-induced contraction." | 1.28 | Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers. ( Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM, 1992) |
| "The cicletanine EC50 was approximately 10(-4) mol/L." | 1.28 | Comparison of the relaxing effects of cicletanine and cromakalim on vascular smooth muscle. ( Deitmer, P; Golenhofen, K; Noack, T, 1992) |
| "Charybdotoxin (ChTX) is a potent blocker of the high-conductance Ca(++)-activated K+ channel in smooth muscle and produces a concentration-dependent contraction of guinea pig trachea." | 1.28 | Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor. ( Charette, L; Garcia, ML; Jones, TR; Kaczorowski, GJ, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (3.08) | 18.7374 |
| 1990's | 134 (68.72) | 18.2507 |
| 2000's | 38 (19.49) | 29.6817 |
| 2010's | 17 (8.72) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Atwal, KS | 2 |
| Grover, GJ | 2 |
| Lodge, NJ | 2 |
| Normandin, DE | 1 |
| Traeger, SC | 1 |
| Sleph, PG | 1 |
| Cohen, RB | 1 |
| Bryson, CC | 1 |
| Dickinson, KE | 1 |
| Soylu, S | 1 |
| Sarac, B | 1 |
| Kurt, A | 1 |
| Altun, A | 1 |
| Cakmak, E | 1 |
| Pence, HH | 1 |
| Kahramanoglu, YE | 1 |
| Bagcivan, I | 4 |
| Mateus, LS | 1 |
| Albuquerque, AAS | 1 |
| Celotto, AC | 1 |
| Evora, PRB | 1 |
| Gai, JW | 1 |
| Wahafu, W | 1 |
| Guo, H | 1 |
| Liu, M | 1 |
| Wang, XC | 1 |
| Xiao, YX | 1 |
| Zhang, L | 1 |
| Xin, ZC | 1 |
| Jin, J | 1 |
| Fitzgerald, R | 1 |
| DeSantiago, B | 1 |
| Lee, DY | 1 |
| Yang, G | 1 |
| Kim, JY | 1 |
| Foster, DB | 1 |
| Chan-Li, Y | 1 |
| Horton, MR | 1 |
| Panettieri, RA | 1 |
| Wang, R | 2 |
| An, SS | 1 |
| Calkovska, A | 1 |
| Uhliarova, B | 1 |
| Joskova, M | 1 |
| Franova, S | 1 |
| Kolomaznik, M | 1 |
| Calkovsky, V | 1 |
| Smolarova, S | 1 |
| Saroj, VK | 1 |
| Nakade, UP | 1 |
| Sharma, A | 1 |
| Yadav, RS | 1 |
| Hajare, SW | 1 |
| Garg, SK | 2 |
| Faruqui, AR | 1 |
| Mathai, J | 1 |
| George, J | 1 |
| Peedicayil, J | 1 |
| Ernest, K | 1 |
| Neelakantan, N | 1 |
| Chen, J | 2 |
| Liu, J | 1 |
| Wang, T | 1 |
| Xiao, H | 1 |
| Yin, C | 1 |
| Yang, J | 1 |
| Chen, X | 1 |
| Ye, Z | 1 |
| Dhaese, I | 1 |
| Lefebvre, RA | 3 |
| Zheng, J | 1 |
| Zheng, P | 1 |
| Zhou, X | 1 |
| Yan, L | 1 |
| Zhou, R | 1 |
| Fu, XY | 1 |
| Dai, GD | 1 |
| Aronsson, P | 1 |
| Andersson, M | 1 |
| Ericsson, T | 1 |
| Giglio, D | 1 |
| Choudhury, S | 1 |
| Singh, TU | 1 |
| Mishra, SK | 1 |
| Ohia, SE | 1 |
| Opere, CA | 1 |
| Monjok, EM | 1 |
| Kouamou, G | 1 |
| Leday, AM | 1 |
| Njie-Mbye, YF | 1 |
| Hehir, MP | 1 |
| Moynihan, AT | 1 |
| Morrison, JJ | 2 |
| Lobov, GI | 1 |
| Pan'kova, MN | 1 |
| Cheng, JT | 3 |
| Chen, IH | 1 |
| Yu, BC | 1 |
| Tong, YC | 1 |
| Lee, LM | 1 |
| Lin, CS | 1 |
| Chung, HH | 2 |
| Lin, KC | 1 |
| Dhungel, KU | 1 |
| Kim, TW | 1 |
| Sharma, N | 2 |
| Bhattarai, JP | 1 |
| Park, SA | 1 |
| Han, SK | 1 |
| Kim, CJ | 1 |
| Chen, W | 1 |
| Yunoki, M | 1 |
| Nakahara, T | 1 |
| Moriuchi, H | 1 |
| Sakamoto, K | 1 |
| Ishii, K | 1 |
| Medeiros, JV | 1 |
| Bezerra, VH | 1 |
| Lucetti, LT | 1 |
| Lima-Júnior, RC | 1 |
| Barbosa, AL | 1 |
| Tavares, BM | 1 |
| Magalhães, PJ | 1 |
| Santos, AA | 1 |
| Cunha, FQ | 1 |
| Soares, PM | 1 |
| Souza, MH | 1 |
| Ademoğlu, F | 1 |
| Başgut, B | 1 |
| Abacioğlu, N | 1 |
| Cakici, I | 1 |
| Bird, NC | 1 |
| Ahmed, R | 1 |
| Chess-Williams, R | 1 |
| Johnson, AG | 1 |
| Kimoto, Y | 1 |
| Kinoshita, H | 3 |
| Nakahata, K | 1 |
| Dojo, M | 1 |
| Iranami, H | 2 |
| Hatano, Y | 3 |
| Rodrigues, AJ | 1 |
| Evora, PR | 1 |
| Pearson, PJ | 1 |
| Schaff, HV | 1 |
| Ruiz Rubio, JL | 1 |
| Hernández, M | 3 |
| Rivera de los Arcos, L | 1 |
| Benedito, S | 2 |
| Recio, P | 1 |
| García, P | 1 |
| García-Sacristán, A | 3 |
| Prieto, D | 4 |
| Glavind-Kristensen, M | 1 |
| Matchkov, V | 1 |
| Hansen, VB | 1 |
| Forman, A | 1 |
| Nilsson, H | 1 |
| Aalkjaer, C | 1 |
| Klockgether-Radke, AP | 1 |
| Pawlowski, P | 1 |
| Neumann, P | 1 |
| Hellige, G | 1 |
| Gilani, AH | 1 |
| Khan, AU | 1 |
| Jabeen, Q | 1 |
| Subhan, F | 1 |
| Ghafar, R | 1 |
| Ohashi, M | 1 |
| Faraci, F | 1 |
| Heistad, D | 1 |
| Fujimoto, S | 1 |
| Mori, M | 1 |
| Tsushima, H | 1 |
| Kunimatsu, M | 1 |
| Ghatta, S | 1 |
| O'Rourke, ST | 2 |
| Kaya, T | 2 |
| Yildirim, MK | 2 |
| Turan, M | 2 |
| Novakovic, A | 1 |
| Gojkovic-Bukarica, L | 1 |
| Peric, M | 2 |
| Nezic, D | 1 |
| Djukanovic, B | 2 |
| Markovic-Lipkovski, J | 1 |
| Heinle, H | 1 |
| Aishima, M | 1 |
| Tomoda, T | 1 |
| Yunoki, T | 2 |
| Nakano, T | 1 |
| Seki, N | 2 |
| Yonemitsu, Y | 1 |
| Sueishi, K | 1 |
| Naito, S | 2 |
| Ito, Y | 3 |
| Teramoto, N | 3 |
| Cho, HC | 1 |
| Sohn, JT | 1 |
| Park, KE | 1 |
| Shin, IW | 1 |
| Chang, KC | 1 |
| Lee, JW | 1 |
| Lee, HK | 1 |
| Chung, YK | 1 |
| Graça, C | 1 |
| Baggio, CH | 1 |
| Freitas, CS | 1 |
| Rattmann, YD | 1 |
| de Souza, LM | 1 |
| Cipriani, TR | 1 |
| Sassaki, GL | 1 |
| Rieck, L | 1 |
| Pontarolo, R | 1 |
| da Silva-Santos, JE | 1 |
| Marques, MC | 1 |
| Gursoy, S | 2 |
| Kaya Temiz, T | 1 |
| Yildirim, S | 1 |
| Yilmaz, A | 1 |
| Ghasemi, M | 1 |
| Sadeghipour, H | 1 |
| Asadi, S | 1 |
| Dehpour, AR | 1 |
| Namekata, I | 1 |
| Yamaguchi, Y | 1 |
| Moriguchi, S | 1 |
| Yamazaki, S | 1 |
| Terasawa, A | 1 |
| Yamagishi, R | 1 |
| Aikawa, T | 1 |
| Saito, T | 1 |
| Kurashima, K | 1 |
| Seri, K | 1 |
| Imamura, Y | 1 |
| Akita, H | 1 |
| Shigenobu, K | 4 |
| Tanaka, H | 3 |
| Jiang, B | 1 |
| Wu, L | 1 |
| Kubo, S | 1 |
| Kajiwara, M | 1 |
| Kawabata, A | 1 |
| Balwierczak, JL | 1 |
| Krulan, CM | 1 |
| Kim, HS | 1 |
| DelGrande, D | 1 |
| Weiss, GB | 1 |
| Hu, S | 1 |
| Khan, SA | 2 |
| Mathews, WR | 1 |
| Meisheri, KD | 2 |
| Bauer, JA | 1 |
| Fung, HL | 1 |
| Zheng, W | 1 |
| Kwon, YW | 1 |
| Gopalakrishnan, M | 2 |
| Triggle, DJ | 1 |
| Hutcheson, IR | 1 |
| Griffith, TM | 1 |
| Tamaoki, J | 2 |
| Tagaya, E | 2 |
| Chiyotani, A | 1 |
| Yamawaki, I | 1 |
| Konno, K | 2 |
| Suthamnatpong, N | 1 |
| Hosokawa, M | 1 |
| Takeuchi, T | 1 |
| Hata, F | 1 |
| Takewaki, T | 2 |
| Hiramatsu, T | 1 |
| Kume, H | 2 |
| Kotlikoff, MI | 1 |
| Takagi, K | 2 |
| Ishibashi, T | 1 |
| Kawada, T | 1 |
| Kato, K | 1 |
| Hamaguchi, M | 1 |
| Imai, S | 1 |
| Parkington, HC | 2 |
| Tonta, MA | 1 |
| Coleman, HA | 2 |
| Tare, M | 2 |
| Kobayashi, D | 1 |
| Todoki, K | 1 |
| Ozono, S | 1 |
| Okabe, E | 1 |
| Murphy, ME | 1 |
| Brayden, JE | 1 |
| Randall, MD | 2 |
| McCulloch, AI | 2 |
| Yokoyama, T | 2 |
| Kasai, H | 3 |
| Okada, Y | 3 |
| Izumi, H | 2 |
| Izawa, T | 2 |
| Ogawa, N | 5 |
| Laurent, F | 2 |
| Michel, A | 3 |
| Bonnet, PA | 2 |
| Chapat, JP | 1 |
| Boucard, M | 2 |
| Kam, KL | 1 |
| Pfaffendorf, M | 2 |
| van Zwieten, PA | 2 |
| Sun, YD | 1 |
| Benishin, CG | 1 |
| McCullough, JR | 1 |
| D'Alonzo, AJ | 1 |
| Sargent, CA | 1 |
| Hatake, K | 1 |
| Wakabayashi, I | 1 |
| Hishida, S | 1 |
| Mellemkjaer, S | 1 |
| Nielsen-Kudsk, JE | 3 |
| Kline, LW | 1 |
| Pang, PK | 1 |
| Kau, ST | 2 |
| Zografos, P | 1 |
| Do, ML | 1 |
| Halterman, TJ | 1 |
| McConville, MW | 1 |
| Yochim, CL | 1 |
| Trivedi, S | 1 |
| Howe, BB | 1 |
| Li, JH | 2 |
| Plane, F | 2 |
| Garland, CJ | 2 |
| Kamei, K | 1 |
| Yoshida, S | 1 |
| Imagawa, J | 1 |
| Nabata, H | 1 |
| Kuriyama, H | 1 |
| Kalsner, S | 2 |
| Martin, PL | 1 |
| Potts, AA | 1 |
| Yu, SM | 2 |
| Lee, SS | 1 |
| Hou, YS | 1 |
| Teng, CM | 3 |
| Norman, NR | 1 |
| Toombs, CF | 1 |
| Buchanan, LV | 1 |
| Cimini, MG | 1 |
| Gibson, JK | 1 |
| Shebuski, RJ | 1 |
| Jiang, C | 1 |
| Collins, P | 1 |
| Gao, Y | 1 |
| Nishimura, Y | 2 |
| Suzuki, A | 2 |
| Yoshida, K | 1 |
| Fukata, Y | 2 |
| Harada, K | 1 |
| Fukushima, H | 3 |
| Kaneta, S | 2 |
| Jinno, Y | 2 |
| Lindeman, KS | 1 |
| Fernandes, LB | 2 |
| Croxton, TL | 1 |
| Hirshman, CA | 1 |
| Thirstrup, S | 1 |
| Hong, SJ | 1 |
| Chang, CC | 1 |
| Nakashima, M | 1 |
| Mombouli, JV | 1 |
| Taylor, AA | 1 |
| Vanhoutte, PM | 1 |
| Faraci, FM | 1 |
| Orgren, K | 1 |
| Heistad, DD | 1 |
| Miwa, A | 1 |
| Motoki, K | 1 |
| Lin, CH | 1 |
| Ko, FN | 2 |
| Wu, YC | 1 |
| Lu, ST | 1 |
| Cowan, CL | 1 |
| Palacino, JJ | 1 |
| Najibi, S | 1 |
| Cohen, RA | 2 |
| Fukushima, S | 1 |
| Ohhashi, T | 1 |
| Buckle, DR | 1 |
| Arch, JR | 1 |
| Bowring, NE | 1 |
| Foster, KA | 1 |
| Taylor, JF | 1 |
| Taylor, SG | 1 |
| Shaw, DJ | 1 |
| Bellan, JA | 1 |
| Longenecker, LL | 1 |
| Kadowitz, PJ | 1 |
| McNamara, DB | 1 |
| Lei, S | 1 |
| Richter, R | 1 |
| Bienert, M | 1 |
| Mulvany, MJ | 2 |
| Merkel, LA | 1 |
| Rivera, LM | 1 |
| Colussi, DJ | 1 |
| Perrone, MH | 1 |
| Smits, GJ | 1 |
| Cox, BF | 1 |
| Halaka, NN | 1 |
| Matsuda, T | 2 |
| Okazaki, K | 1 |
| Kato, Y | 1 |
| Yasay, GD | 1 |
| Simonsen, U | 3 |
| Sánez de Tejada, I | 1 |
| Fukushima, T | 1 |
| Hirasaki, A | 1 |
| Jones, KA | 1 |
| Warner, DO | 1 |
| Holland, M | 1 |
| Langton, PD | 1 |
| Standen, NB | 2 |
| Boyle, JP | 2 |
| Hadjkaddour, K | 1 |
| Naline, E | 1 |
| Cui, YY | 1 |
| Bakdach, H | 1 |
| Advenier, C | 2 |
| Song, P | 1 |
| Rocchi, D | 1 |
| Lazzarotti, M | 1 |
| Crimi, E | 1 |
| Rehder, K | 1 |
| Brusasco, V | 1 |
| Yoshiizumi, K | 1 |
| Ikeda, S | 1 |
| Goto, K | 1 |
| Morita, T | 1 |
| Nishimura, N | 1 |
| Sukamoto, T | 1 |
| Yoshino, K | 1 |
| Paulino, N | 2 |
| Cechinel-Filho, V | 1 |
| Yunes, RA | 2 |
| Calixto, JB | 2 |
| Bharadwaj, LA | 1 |
| Prasad, K | 1 |
| Fujiwara, T | 1 |
| Angus, JA | 1 |
| Hüsken, BC | 1 |
| Vroom, MB | 1 |
| Timmenga, EJ | 1 |
| Okamura, T | 1 |
| Ayajiki, K | 1 |
| Kangawa, K | 1 |
| Toda, N | 1 |
| Kamata, K | 1 |
| Kondoh, H | 1 |
| Orensanz, LM | 1 |
| Barahona, MV | 1 |
| Jiménez-Cidre, M | 1 |
| Rivera, L | 1 |
| Gao, YJ | 1 |
| Nakai, Y | 1 |
| Mikawa, K | 1 |
| Bottrill, FE | 1 |
| Hiley, CR | 1 |
| Jones, RB | 1 |
| Dickinson, K | 1 |
| Anthony, DM | 1 |
| Marita, AR | 1 |
| Kaul, CL | 1 |
| Buckett, WR | 1 |
| Dodd-o, JM | 1 |
| Zheng, G | 1 |
| Silverman, HS | 1 |
| Lakatta, EG | 1 |
| Ziegelstein, RC | 1 |
| Zakharenko, SS | 1 |
| Nesterov, AV | 1 |
| Shipachev, VV | 1 |
| Gusev, AS | 1 |
| Serebriakov, VN | 1 |
| Huang, Y | 2 |
| Kwok, KH | 2 |
| Lawson, K | 1 |
| Barras, M | 1 |
| Armstrong, JM | 1 |
| Hicks, PE | 1 |
| Isono, K | 1 |
| Kondo, M | 1 |
| Matsumoto, T | 1 |
| Takahashi, M | 1 |
| Omura, T | 1 |
| Takaoka, A | 1 |
| Liu, Q | 1 |
| Nakae, I | 1 |
| Kinoshita, M | 1 |
| Nagata, S | 1 |
| Takeyama, K | 1 |
| Hosoki, K | 1 |
| Karasawa, T | 1 |
| Akar, F | 1 |
| Uydeş-Dogan, BS | 1 |
| Tufan, H | 1 |
| Aşlamaci, S | 1 |
| Köksoy, C | 1 |
| Kanzik, I | 1 |
| Geary, GG | 1 |
| Maeda, G | 1 |
| Gonzalez, RR | 1 |
| Zhu, P | 1 |
| Bény, JL | 1 |
| Flammer, J | 1 |
| Lüscher, TF | 1 |
| Haefliger, IO | 1 |
| Mehta, AA | 1 |
| Santani, DD | 1 |
| Goyal, RK | 1 |
| Szilvassy, Z | 1 |
| Lonovics, J | 1 |
| Jakab, I | 1 |
| Nagy, I | 1 |
| Suarez-Kurtz, G | 1 |
| Nascimento, JH | 1 |
| Ondeyka, JG | 1 |
| Kaczorowski, GJ | 2 |
| Sheridan, BC | 1 |
| McIntyre, RC | 1 |
| Meldrum, DR | 1 |
| Fullerton, DA | 1 |
| Gojkoviíc Bukarica, L | 1 |
| Kazić, T | 1 |
| Sajić, Z | 1 |
| Panić, G | 1 |
| Bojić, M | 1 |
| Kawahara, J | 1 |
| Takeuchi, A | 1 |
| Elmedal, B | 1 |
| Wiley, KE | 1 |
| Jeremy, JY | 1 |
| Shimizu, S | 1 |
| Paul, RJ | 1 |
| Khan, RN | 1 |
| Smith, SK | 1 |
| Ashford, ML | 1 |
| Van Lunteren, E | 1 |
| Moyer, M | 1 |
| Torres, A | 1 |
| Chiou, WF | 1 |
| Chen, CF | 1 |
| Davie, CS | 1 |
| Kubo, M | 1 |
| Kwan, YW | 1 |
| To, KW | 1 |
| Lau, WM | 1 |
| Tsang, SH | 1 |
| Brading, AF | 1 |
| Kim, ND | 2 |
| Kang, SY | 2 |
| Park, JH | 2 |
| Schini-Kerth, VB | 2 |
| Kim, MJ | 1 |
| Sunano, S | 1 |
| Watanabe, H | 1 |
| Tanaka, S | 3 |
| Sekiguchi, F | 1 |
| Shimamura, K | 1 |
| Dumas, JP | 1 |
| Goirand, F | 1 |
| Bardou, M | 1 |
| Dumas, M | 1 |
| Rochette, L | 1 |
| Giudicelli, JF | 1 |
| Wu, CC | 2 |
| Chen, SJ | 2 |
| Yen, MH | 2 |
| Satake, N | 1 |
| Imanishi, M | 1 |
| Shibata, S | 1 |
| Ergün, H | 1 |
| Ayhan, IH | 1 |
| Tulunay, FC | 1 |
| Tanaka, Y | 1 |
| Otsuka, A | 1 |
| Pizollatti, MG | 1 |
| Filho, VC | 1 |
| Creczynski-Pasa, TB | 1 |
| Honda, H | 1 |
| Unemoto, T | 1 |
| Kogo, H | 1 |
| Ishikawa, T | 1 |
| Buchheit, KH | 1 |
| Hofmann, A | 1 |
| Manley, P | 1 |
| Pfannkuche, HJ | 1 |
| Quast, U | 3 |
| Hudman, D | 1 |
| Elliott, RA | 1 |
| Norman, RI | 1 |
| Yang, SN | 1 |
| Lin, CI | 1 |
| Kakutani, T | 1 |
| Hsieh, GC | 1 |
| Kolasa, T | 1 |
| Sullivan, JP | 1 |
| Brioni, JD | 1 |
| Dick, JM | 1 |
| Van Molle, W | 1 |
| Libert, C | 1 |
| Grbović, L | 1 |
| Radenković, M | 1 |
| Prostran, M | 1 |
| Pesić, S | 1 |
| Devillier, P | 1 |
| Corompt, E | 1 |
| Bréant, D | 1 |
| Caron, F | 1 |
| Bessard, G | 1 |
| Ikawa, S | 1 |
| Takano, N | 1 |
| Tanaka, K | 1 |
| Kafali, H | 1 |
| Karadas, B | 1 |
| Sarioglu, Y | 1 |
| Gopalakrishnan, SM | 1 |
| Buckner, SA | 1 |
| Milicic, I | 1 |
| Groebe, DR | 1 |
| Whiteaker, KL | 1 |
| Burns, DJ | 1 |
| Warrior, U | 1 |
| Downing, SJ | 1 |
| Hollingsworth, M | 1 |
| Holzmann, S | 1 |
| Kukovetz, WR | 1 |
| Braida, C | 1 |
| Pöch, G | 1 |
| Ito, K | 1 |
| Kanno, T | 1 |
| Suzuki, K | 1 |
| Masuzawa-Ito, K | 1 |
| Ohashi, H | 1 |
| Asano, M | 2 |
| Suzuki, H | 1 |
| Su, MJ | 1 |
| Wu, TS | 1 |
| Wang, ML | 1 |
| Huang, TF | 1 |
| Calder, JA | 1 |
| Schachter, M | 1 |
| Sever, PS | 1 |
| Deitmer, P | 1 |
| Golenhofen, K | 1 |
| Noack, T | 1 |
| Small, RC | 2 |
| Berry, JL | 1 |
| Foster, RW | 1 |
| Blarer, S | 1 |
| Hattori, Y | 1 |
| Nagashima, M | 1 |
| Endo, Y | 1 |
| Kanno, M | 1 |
| Spina, D | 1 |
| Preuss, JM | 1 |
| Hay, DW | 1 |
| Muccitelli, RM | 1 |
| Page, CP | 1 |
| Goldie, RG | 1 |
| Eckman, DM | 1 |
| Frankovich, JD | 1 |
| Keef, KD | 1 |
| Bray, K | 1 |
| Horacek, J | 1 |
| Martin, GR | 1 |
| Bolofo, ML | 1 |
| Giles, H | 1 |
| Parsons, AA | 1 |
| Schilling, L | 1 |
| Wahl, M | 1 |
| Borg, C | 1 |
| Mondot, S | 1 |
| Mestre, M | 1 |
| Cavero, I | 1 |
| Jones, TR | 1 |
| Charette, L | 1 |
| Garcia, ML | 1 |
| Longmore, J | 1 |
| Newgreen, DT | 1 |
| Weston, AH | 2 |
| Nyborg, NC | 1 |
| Corrêa, DS | 1 |
| Rabetti, AC | 1 |
| Rae, GA | 1 |
| Van de Voorde, J | 1 |
| Vanheel, B | 1 |
| Leusen, I | 1 |
| de Moura, RS | 1 |
| Jasbik, W | 1 |
| Shikada, K | 1 |
| Yamamoto, A | 1 |
| Masuda, Y | 1 |
| Arakawa, C | 1 |
| Yamashita, T | 1 |
| Miyajima, M | 1 |
| Kasuya, Y | 1 |
| Steinberg, MI | 1 |
| Wiest, SA | 1 |
| Zimmerman, KM | 1 |
| Ertel, PJ | 1 |
| Bemis, KG | 1 |
| Robertson, DW | 1 |
| Raeburn, D | 1 |
| Brown, TJ | 1 |
| Elliott, DA | 1 |
| Gu, M | 1 |
| Ong, BY | 1 |
| Bose, D | 1 |
| Bang, L | 1 |
| Brønsgaard, AM | 1 |
| Masuzawa, K | 1 |
| Lebrun, P | 1 |
| Fang, ZY | 1 |
| Antoine, MH | 1 |
| Herchuelz, A | 1 |
| Hermann, M | 1 |
| Berkenboom, G | 1 |
| Fontaine, J | 1 |
| Yanagisawa, T | 1 |
| Teshigawara, T | 1 |
| Taira, N | 1 |
| Buckingham, RE | 1 |
| Hamilton, TC | 1 |
| Howlett, DR | 1 |
| Mootoo, S | 1 |
| Wilson, C | 1 |
| Murray, MA | 1 |
| Bray, KM | 1 |
| Duty, S | 1 |
| Perkins, RS | 1 |
| Paciorek, PM | 1 |
| Waterfall, JF | 1 |
| Eltze, M | 1 |
| Villar, A | 1 |
| Ivorra, MD | 1 |
| D'Ocon, MP | 1 |
| Anselmi, E | 1 |
195 other studies available for glyburide and Muscle Relaxation
| Article | Year |
|---|---|
Binding of ATP-sensitive potassium channel (KATP) openers to cardiac membranes: correlation of binding affinities with cardioprotective and smooth muscle relaxing potencies.
Topics: Animals; ATP-Binding Cassette Transporters; Cardiotonic Agents; Dogs; KATP Channels; Muscle Relaxati | 1998 |
Investigation the relaxant effects of proton pump ınhibitors and their relaxation mechanism on sheep sphincter of Oddi.
Topics: 4-Aminopyridine; Animals; Cholangiopancreatography, Endoscopic Retrograde; Glyburide; Male; Muscle R | 2019 |
In vitro evidence that endothelium-dependent vasodilatation induced by clozapine is mediated by an ATP-sensitive potassium channel.
Topics: Adenosine Triphosphate; Animals; Apamin; Clozapine; Cyclic GMP; Endothelium, Vascular; Glyburide; Ma | 2019 |
Further evidence of endogenous hydrogen sulphide as a mediator of relaxation in human and rat bladder.
Topics: Aged; Alkynes; Animals; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cysteine; Glyburide; | 2013 |
H2S relaxes isolated human airway smooth muscle cells via the sarcolemmal K(ATP) channel.
Topics: Bronchi; Bronchodilator Agents; Cells, Cultured; Cystathionine gamma-Lyase; Glyburide; Humans; Hydro | 2014 |
Pulmonary surfactant in the airway physiology: a direct relaxing effect on the smooth muscle.
Topics: Animals; Biological Products; Cystic Fibrosis Transmembrane Conductance Regulator; Dose-Response Rel | 2015 |
Functional involvement of L-type calcium channels and cyclic nucleotide-dependent pathways in cadmium-induced myometrial relaxation in rats.
Topics: 4-Aminopyridine; Animals; Cadmium; Calcium Channels, L-Type; Cyclic GMP; Female; Glyburide; In Vitro | 2017 |
Inhibitory effect of nicorandil on the contraction of isolated human urinary bladder detrusor muscle.
Topics: Child; Child, Preschool; Electromyography; Female; Glyburide; Humans; Hypoglycemic Agents; In Vitro | 2008 |
The relaxation mechanisms of tetrandrine on the rabbit corpus cavernosum tissue in vitro.
Topics: 4-Aminopyridine; Animals; Benzylisoquinolines; Drugs, Chinese Herbal; Enzyme Inhibitors; Glyburide; | 2009 |
Myosin light chain phosphatase activation is involved in the hydrogen sulfide-induced relaxation in mouse gastric fundus.
Topics: Adenine; Amides; Animals; Enzyme Activation; Gastric Fundus; Glyburide; Hydrogen Sulfide; In Vitro T | 2009 |
Relaxant effects of matrine on aortic smooth muscles of guinea pigs.
Topics: Alkaloids; Animals; Aorta; Calcium; Culture Media; Dose-Response Relationship, Drug; Glyburide; Guin | 2009 |
Assessment and characterization of purinergic contractions and relaxations in the rat urinary bladder.
Topics: Adenine Nucleotides; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Drug Antagonism; Electr | 2010 |
Cellular coupling of potassium channels with beta2 adrenoceptors in mediating myometrial relaxation in buffaloes (Bubalus bubalis).
Topics: 4-Aminopyridine; Adrenergic beta-Agonists; Albuterol; Animals; Buffaloes; Cromakalim; Female; Glybur | 2010 |
Role of hydrogen sulfide production in inhibitory action of L-cysteine on isolated porcine irides.
Topics: Animals; Carbachol; Cholinergic Agonists; Cystathionine beta-Synthase; Cystathionine gamma-Lyase; Cy | 2010 |
Relaxant effect of Levosimendan on human uterine contractility in vitro.
Topics: Case-Control Studies; Dose-Response Relationship, Drug; Female; Glyburide; Humans; Hydrazones; In Vi | 2010 |
[NO-dependent. Modulation of contractile function in capsule of lymph nodes].
Topics: Acetylcholine; Animals; Cattle; Cholinergic Agents; Dose-Response Relationship, Drug; Endothelium, L | 2010 |
Loperamide-induced rat prostate relaxation through activation of peripheral µ-opioid receptors.
Topics: Analysis of Variance; Animals; Blotting, Western; Dose-Response Relationship, Drug; Glyburide; In Vi | 2011 |
Urinary bladder relaxation through activation of opioid μ-receptors induced by loperamide is increased in diabetic rats.
Topics: Animals; Antidiarrheals; Cells, Cultured; Diabetes Mellitus, Experimental; Glyburide; Hypoglycemic A | 2012 |
Magnesium increases iberiotoxin-sensitive large conductance calcium activated potassium currents on the basilar artery smooth muscle cells in rabbits.
Topics: Animals; Apamin; Basilar Artery; Calcium; Cells, Cultured; Glyburide; Large-Conductance Calcium-Acti | 2012 |
Opiate-induced constipation related to activation of small intestine opioid μ2-receptors.
Topics: Acetylcholine; Analgesics, Opioid; Animals; Antidiarrheals; Constipation; Cyclic AMP; Cyclic AMP-Dep | 2012 |
The relaxant action of nicorandil in bovine tracheal smooth muscle.
Topics: Animals; Cattle; Cromakalim; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; In Vitro Techniques; M | 2012 |
Role of KATP channels and TRPV1 receptors in hydrogen sulfide-enhanced gastric emptying of liquid in awake mice.
Topics: Animals; Capsaicin; Gastric Emptying; Glyburide; Hydrogen Sulfide; KATP Channels; Male; Mice; Muscle | 2012 |
The mechanisms of peroxynitrite-induced relaxations in isolated rat anococcygeus muscle.
Topics: Animals; Antioxidants; Glyburide; Guanylate Cyclase; In Vitro Techniques; Male; Muscle Relaxation; M | 2002 |
Active relaxation of human gallbladder muscle is mediated by ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Carbachol; Cromakalim; Gallbladder; Glyburide; Guinea Pigs; Humans; | 2002 |
Mexiletine differentially modulates vasorelaxation mediated by adenosine triphosphate-sensitive K+ channels in aortas from normotensive and hypertensive rats.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; ATP-Binding Cassette Transporters; Cromakalim; Dos | 2003 |
Endothelium-dependent relaxation to poly-L-arginine in canine coronary arteries.
Topics: Acetylcholine; Animals; Coronary Vessels; Dogs; Endothelium, Vascular; Glyburide; Indomethacin; Musc | 2003 |
Role of ATP-sensitive K+ channels in relaxation of penile resistance arteries.
Topics: Adenosine Triphosphate; Animals; Arteries; Cromakalim; Erectile Dysfunction; Glyburide; Horses; Huma | 2004 |
KATP-channel-induced vasodilation is modulated by the Na,K-pump activity in rabbit coronary small arteries.
Topics: Animals; Arteries; ATP-Binding Cassette Transporters; Cardiotonic Agents; Coronary Vessels; Cromakal | 2004 |
Mechanisms involved in the relaxing effect of midazolam on coronary arteries.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Coronary Vessels; Dinoprostone; Dose-Response Rela | 2005 |
Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation.
Topics: Animals; Cromakalim; Glyburide; Guinea Pigs; Hypoglycemic Agents; Ileum; In Vitro Techniques; Jejunu | 2005 |
Peroxynitrite hyperpolarizes smooth muscle and relaxes internal carotid artery in rabbit via ATP-sensitive K+ channels.
Topics: Animals; Antioxidants; Azoles; Carotid Artery, Internal; Catalase; Charybdotoxin; Glyburide; Hydroge | 2005 |
Capsaicin-induced, capsazepine-insensitive relaxation of the guinea-pig ileum.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Apamin; Barium; Benzopyrans; Caffeine; Calcitonin Gene-Rela | 2006 |
Nitroglycerin-induced release of calcitonin gene-related peptide from sensory nerves attenuates the development of nitrate tolerance.
Topics: Animals; Aorta, Thoracic; Calcitonin Gene-Related Peptide; Capsaicin; Diltiazem; Dose-Response Relat | 2006 |
Investigation of the relaxant effects of pinacidil and cromakalim on the sheep sphincter of Oddi.
Topics: Animals; Cromakalim; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Parasympatholytics; Pi | 2006 |
The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery.
Topics: 4-Aminopyridine; Anti-Arrhythmia Agents; Charybdotoxin; Coronary Artery Bypass; Coronary Disease; Gl | 2006 |
Actions of ZD0947, a novel ATP-sensitive K+ channel opener, on membrane currents in human detrusor myocytes.
Topics: ATP-Binding Cassette Transporters; Carbachol; Diazoxide; Dihydropyridines; Dose-Response Relationshi | 2006 |
Inhibitory effect of tramadol on vasorelaxation mediated by ATP-sensitive K+ channels in rat aorta.
Topics: Analgesics, Opioid; Animals; Aorta; Calcium Channel Blockers; Cromakalim; Data Interpretation, Stati | 2007 |
In vivo assessment of safety and mechanisms underlying in vitro relaxation induced by Mikania laevigata Schultz Bip. ex Baker in the rat trachea.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Brazil; Coumarins; Dose-Response Relationship, Drug; Female | 2007 |
Investigation of relaxant effects of propofol on sheep sphincter of Oddi.
Topics: 4-Aminopyridine; Anesthetics, Intravenous; Animals; Dose-Response Relationship, Drug; Drug Combinati | 2007 |
Time-dependent alteration in cromakalim-induced relaxation of corpus cavernosum from streptozocin-induced diabetic rats.
Topics: Animals; Cromakalim; Diabetes Mellitus, Experimental; Dose-Response Relationship, Drug; Glyburide; I | 2007 |
(R)-ACX, a pancreatic beta-cell selective sulfonylurea, does not aggravate myocardial ischemia-reperfusion damage.
Topics: Action Potentials; Animals; Benzopyrans; Cells, Cultured; Female; Glyburide; Guinea Pigs; Hypoglycem | 2007 |
Sulphonylureas induced vasorelaxation of mouse arteries.
Topics: Adamantane; Animals; Arteries; Endothelium, Vascular; Glyburide; In Vitro Techniques; KATP Channels; | 2007 |
Dual modulation of the tension of isolated gastric artery and gastric mucosal circulation by hydrogen sulfide in rats.
Topics: Animals; Arteries; Biological Factors; Blood Pressure; Endothelium, Vascular; Gastric Mucosa; Glybur | 2007 |
Evidence that BKCa channel activation contributes to K+ channel opener induced relaxation of the porcine coronary artery.
Topics: Animals; Benzopyrans; Calcium; Charybdotoxin; Coronary Vessels; Electrophysiology; Glyburide; Guanid | 1995 |
Role of calcium-activated K+ channels in vasodilation induced by nitroglycerine, acetylcholine and nitric oxide.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Calcium; Charybdotoxin; Colforsin; Drug Interactions | 1993 |
Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Binding Sites; Drug Tolerance; Glyburide; Heart | 1993 |
Heterogeneous populations of K+ channels mediate EDRF release to flow but not agonists in rabbit aorta.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Abdominal; Apamin; Arginine; Biological Assay | 1994 |
Role of K+ channel opening and Na(+)-K+ ATPase activity in airway relaxation induced by salbutamol.
Topics: Albuterol; Analysis of Variance; Animals; Apamin; Bronchi; Charybdotoxin; Dogs; Dose-Response Relati | 1994 |
Nitric oxide-mediated inhibitory response of rat proximal colon: independence from changes in membrane potential.
Topics: Animals; Apamin; Arginine; Cell Membrane; Charybdotoxin; Colon; Electric Stimulation; Glyburide; Mal | 1994 |
Role of calcium-activated potassium channels in the relaxation of tracheal smooth muscles by forskolin.
Topics: Animals; Apamin; Calcium; Carbachol; Charybdotoxin; Colforsin; Cyclic AMP; Drug Interactions; Electr | 1994 |
Contribution of activation of K+ channels to glyceryl trinitrate-induced relaxation of rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Apamin; Charybdotoxin; Cyclic GMP; En | 1995 |
Role of membrane potential in endothelium-dependent relaxation of guinea-pig coronary arterial smooth muscle.
Topics: Acetylcholine; Animals; Coronary Vessels; Dose-Response Relationship, Drug; Female; Glyburide; Guine | 1995 |
Calcitonin gene-related peptide mediated neurogenic vasorelaxation in the isolated canine lingual artery.
Topics: Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Capsaicin; Cromakalim; Dogs; Electr | 1995 |
Nitric oxide hyperpolarizes rabbit mesenteric arteries via ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Biological Factors; Glyburide; In Vitro Techniques; Membrane Potent | 1995 |
The involvement of ATP-sensitive potassium channels in beta-adrenoceptor-mediated vasorelaxation in the rat isolated mesenteric arterial bed.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; B | 1995 |
Effect of Kil769, a novel K(+)-channel opener, on sensitivity to Ca2+ of contractile elements and inositol phosphate formation in porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Calcium Channe | 1995 |
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.
Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoprote | 1993 |
Drug-induced endothelium-dependent and -independent relaxations in isolated resistance vessels taken from simultaneously hypertensive and streptozotocin-diabetic rats.
Topics: Animals; Benzopyrans; Bradykinin; Calcium; Cromakalim; Diabetes Mellitus, Experimental; Endothelium, | 1994 |
K+ channel openers relax longitudinal muscle of guinea pig ileum.
Topics: Animals; Calcitonin Gene-Related Peptide; Glyburide; Guinea Pigs; Ileum; In Vitro Techniques; Muscle | 1994 |
Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Aorta; Benzopyrans; Cromakalim; Decanoic Ac | 1995 |
Endothelium-dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Atropine; Biological Factor | 1995 |
Glibenclamide inhibits hypoxic relaxation of isolated porcine coronary arteries under conditions of impaired glycolysis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1994 |
Calcitonin gene-related peptide relaxes cholecystokinin-induced tension in Iguana iguana gallbladder strips.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Cholecystokinin; Gallbladder; Glyburide; Iguanas | 1994 |
Characterization of ATP-sensitive potassium channel-blocking activity of ZENECA ZM181,037, a eukalemic diuretic.
Topics: Acetamides; Adenosine Triphosphate; Administration, Oral; Animals; Benzopyrans; Blood Glucose; Blood | 1994 |
Smooth muscle hyperpolarization and relaxation to acetylcholine in the rabbit basilar artery.
Topics: Acetylcholine; Animals; Basilar Artery; Female; Glyburide; In Vitro Techniques; Male; Membrane Poten | 1994 |
Regional and species differences in glyburide-sensitive K+ channels in airway smooth muscles as estimated from actions of KC 128 and levcromakalim.
Topics: Animals; Benzopyrans; Bronchi; Carbachol; Cromakalim; Dogs; Dose-Response Relationship, Drug; Female | 1994 |
Propranolol antagonizes coronary artery relaxation by a potassium channel opener.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Biological Transport; Cattle; Colfor | 1994 |
The endothelium of the rat renal artery plays an obligatory role in A2 adenosine receptor-mediated relaxation induced by 5'-N-ethylcarboxamidoadenosine and N6-cyclopentyladenosine.
Topics: Adenosine; Adenosine-5'-(N-ethylcarboxamide); Animals; Arginine; Endothelium, Vascular; Glyburide; I | 1994 |
Mechanisms of vasorelaxation induced by N-allylsecoboldine in rat thoracic aorta.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Aorta, Thoracic; Aporphines; Benzopyrans; Calcium | 1994 |
Comparative effects of the potassium channel openers cromakalim and pinacidil and the cromakalim analog U-89232 on isolated vascular and cardiac tissue.
Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Female; Glyburide; Guanidines; M | 1994 |
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vasc | 1994 |
Relaxant effects of calcitonin gene-related peptide on isolated small renal arteries in stroke-prone spontaneously hypertensive rats.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Colforsin; Dose-Response Relationship, Drug | 1994 |
Dissimilarity in the mechanisms of action of KRN2391, nicorandil and cromakalim in canine renal artery.
Topics: Animals; Benzopyrans; Cromakalim; Dogs; Female; Glyburide; In Vitro Techniques; Male; Methylene Blue | 1993 |
Mechanism of action of KRN2391 in canine coronary vascular bed.
Topics: Animals; Antihypertensive Agents; Arteries; Benzopyrans; Coronary Circulation; Coronary Vessels; Cro | 1993 |
Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro.
Topics: Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Carbachol; Cromakalim; Dose-Response Relations | 1994 |
Effects of antidiabetic sulphonylureas, cromakalim and their interaction in guinea-pig isolated tracheal smooth muscle.
Topics: Animals; Benzopyrans; Cromakalim; Drug Interactions; Glipizide; Glyburide; Guinea Pigs; Hypoglycemic | 1993 |
O2 occlusion and cyanide induced immediate relaxation and contraction of murine skeletal muscle.
Topics: Animals; Caffeine; Cyanides; Electric Stimulation; Glyburide; Hypoxia; In Vitro Techniques; Mice; Mi | 1993 |
Endothelium-dependent hyperpolarization caused by bradykinin in human coronary arteries.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Arginine; Benzopyrans; Bradykinin; Calcimycin; Child | 1993 |
Impaired relaxation of the carotid artery during activation of ATP-sensitive potassium channels in atherosclerotic monkeys.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arteriosclerosis; Carotid Arteries; Carotid Artery D | 1994 |
Vasorelaxant mechanism of KRN2391 and nicorandil in porcine coronary arteries of different sizes.
Topics: Animals; Benzopyrans; Coronary Vessels; Cromakalim; Glyburide; In Vitro Techniques; Muscle Relaxatio | 1993 |
The relaxant actions on guinea-pig trachealis of atherosperminine isolated from Fissistigma glaucescens.
Topics: Alkaloids; Animals; Benzopyrans; Calcium; Calmodulin; Colforsin; Cromakalim; Cyclic AMP; Cyclic GMP; | 1993 |
Potassium channel-mediated relaxation to acetylcholine in rabbit arteries.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Aorta, Thoracic; Arginine; Cyclic GMP; Endothelium, Vascul | 1993 |
Acetylcholine-induced endothelium-independent relaxations in monkey isolated superior and inferior caval veins.
Topics: Acetylcholine; Animals; Arginine; Aspirin; Calcimycin; Dinoprost; Endothelium, Vascular; Female; Gly | 1993 |
Relaxant effects of the potassium channel activators BRL 38227 and pinacidil on guinea-pig and human airway smooth muscle, and blockade of their effects by glibenclamide and BRL 31660.
Topics: Animals; Anti-Arrhythmia Agents; Benzopyrans; Bronchi; Cromakalim; Female; Glyburide; Guanidines; Gu | 1993 |
Selective and complete blockade of acetylcholine-induced relaxation in rabbit aortic rings by N omega-nitro-L-arginine but not by glybenclamide.
Topics: Acetylcholine; Animals; Aorta, Abdominal; Arginine; Benzopyrans; Cromakalim; Endothelium, Vascular; | 1993 |
Relaxing actions of corticotropin-releasing factor on rat resistance arteries.
Topics: Animals; Arteries; Blood Pressure; Corticotropin-Releasing Hormone; Glyburide; Heart Rate; In Vitro | 1993 |
In vitro and in vivo characterization of an A1-selective adenosine agonist, RG14202.
Topics: Adenosine; Animals; Binding Sites; Carotid Arteries; Coronary Vessels; Cyclopentanes; Dinoprost; Dog | 1993 |
8-(Diethylamino)-octyl-3,4,5-trimethoxybenzoate inhibits cromakalim-induced 86Rb efflux from the rat aorta.
Topics: Animals; Aorta; Benzopyrans; Biological Transport; Cromakalim; Gallic Acid; Glyburide; In Vitro Tech | 1993 |
Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arteries; Calcium; Calcium Channel Blockers; Cattle; Cor | 1995 |
K+ channel-opening properties of a novel compound, NIP-121, in guinea pig myocardium as compared with those of cromakalim.
Topics: Action Potentials; Adenosine Triphosphate; Analysis of Variance; Animals; Benzopyrans; Cromakalim; D | 1995 |
Mechanoinhibitory effect of estradiol in guinea pig urinary bladder smooth muscles.
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Estradiol; Glyburide; Guinea Pigs; Hypogl | 1995 |
Involvement of nitric oxide in the non-adrenergic non-cholinergic neurotransmission of horse deep penile arteries: role of charybdotoxin-sensitive K(+)-channels.
Topics: Adrenergic Fibers; Animals; Arginine; Charybdotoxin; Cholinergic Fibers; Electric Stimulation; Endot | 1995 |
Halothane and potassium channels in airway smooth muscle.
Topics: Acetylcholine; Anesthetics, Inhalation; Animals; Benzoxazines; Cholinergic Agents; Cyclic N-Oxides; | 1996 |
KATP channel activation mediates nicorandil-induced relaxation of nitrate-tolerant coronary arteries.
Topics: Animals; Coronary Vessels; Dose-Response Relationship, Drug; Drug Tolerance; Glyburide; In Vitro Tec | 1996 |
Effects of the BKCa channel activator, NS1619, on rat cerebral artery smooth muscle.
Topics: Animals; Apamin; Benzimidazoles; Calcium; Cerebral Arteries; Glyburide; Male; Membrane Potentials; M | 1996 |
Smooth muscle relaxant activity of A1- and A2-selective adenosine receptor agonists in guinea pig trachea: involvement of potassium channels.
Topics: Adenosine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glyburide; Guinea Pi | 1996 |
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Croma | 1996 |
Postjunctional effect of pinacidil on contractility of isolated bovine trachealis.
Topics: Acetylcholine; Animals; Cattle; Cell Membrane; Dose-Response Relationship, Drug; Electric Stimulatio | 1996 |
Synthesis and structure-activity relationships of novel phenylcyanoguanidine derivatives as potassium channel openers.
Topics: Animals; Blood Pressure; Glyburide; Guanidines; Guinea Pigs; Heart Rate; Hypoglycemic Agents; Ileum; | 1996 |
The relaxant effect of extract of Phyllanthus urinaria in the guinea-pig isolated trachea. Evidence for involvement of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Apamin; Ben | 1996 |
Mechanism of hydroxyl radical-induced modulation of vascular tone.
Topics: Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hydroxyl Radical; Indomethacin; | 1997 |
Analysis of relaxation and repolarization mechanisms of nicorandil in rat mesenteric artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Calcium Ch | 1996 |
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adolesce | 1995 |
Mechanism of adrenomedullin-induced relaxation in isolated canine retinal arteries.
Topics: Adrenomedullin; Animals; Calcitonin Gene-Related Peptide; Cyclic AMP; Cyclic GMP; Cyclooxygenase Inh | 1997 |
Impairment of endothelium-dependent relaxation of the isolated basilar artery from streptozotocin-induced diabetic rats.
Topics: 1-Methyl-3-isobutylxanthine; Acetylcholine; Animals; Basilar Artery; Diabetes Mellitus, Experimental | 1996 |
Involvement of a glibenclamide-sensitive mechanism in the nitrergic neurotransmission of the pig intravesical ureter.
Topics: Animals; Female; Glyburide; Guanylate Cyclase; In Vitro Techniques; Male; Methylene Blue; Muscle Rel | 1997 |
Calcitonin gene-related peptide-induced relaxation in isolated small superior mesenteric arteries from adult stroke-prone spontaneously hypertensive rats.
Topics: Animals; Calcitonin Gene-Related Peptide; Cerebrovascular Disorders; Cyclic AMP; Glyburide; Hypoglyc | 1995 |
Effects of BKCa channels on the reduction of cytosolic Ca2+ in cGMP-induced relaxation of guinea-pig trachea.
Topics: Animals; Apamin; Atrial Natriuretic Factor; Calcium; Cyclic GMP; Cytosol; Extracellular Space; Glybu | 1997 |
Characterization and modulation of EDHF-mediated relaxations in the rat isolated superior mesenteric arterial bed.
Topics: Animals; Biological Factors; Carbachol; Clotrimazole; Cyclic GMP; Drug Interactions; Enzyme Inhibito | 1997 |
Evaluation of BTS 67 582, a novel antidiabetic agent, in normal and diabetic rats.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Blood Glucose; Brain; Cromakalim; Diabetes Mellitus, Experime | 1997 |
Endothelium-independent relaxation of aortic rings by the nitric oxide synthase inhibitor diphenyleneiodonium.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta; Dose-Response Relationship, Drug; Endothelium, Vascula | 1997 |
[Role of potassium channels in endothelium-dependent relaxation of the rat mesenteric artery].
Topics: Adenosine Triphosphate; Animals; Calcium Channel Blockers; Calcium Channels; Endothelium, Vascular; | 1997 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotox | 1997 |
Effects of K+ channel inhibitors and antagonists on NS-004 evoked relaxations in guinea-pig isolated trachea.
Topics: Animals; Anti-Arrhythmia Agents; Apamin; Benzimidazoles; Charybdotoxin; Chlorophenols; Dose-Response | 1997 |
Role of Ca(2+)-activated K+ channel in epithelium-dependent relaxation of human bronchial smooth muscle.
Topics: Acetylcholine; Apamin; Bronchi; Calcium; Glyburide; Humans; Hypoglycemic Agents; Muscle Contraction; | 1997 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Fem | 1997 |
Possible involvement of ATP-dependent K-channel related mechanisms in the antihypertensive and cough suppressant effects of the novel ACE inhibitor (2S, 3aS, 7aS)-1-(N2-nicotinoyl-L-lysyl-gamma-D-glutamyl)octahydro-1H- indole-2-carboxylic acid.
Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; | 1997 |
The comparison of the responsiveness of human isolated internal mammary and gastroepiploic arteries to levcromakalim: an alternative approach to the management of graft spasm.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Benzopyrans; Coronary | 1997 |
Endothelium-dependent vascular smooth muscle relaxation activated by electrical field stimulation.
Topics: Animals; Aorta, Thoracic; Calcium Channel Blockers; Cattle; Diltiazem; Electric Stimulation; Endothe | 1997 |
Relaxation by bradykinin in porcine ciliary artery. Role of nitric oxide and K(+)-channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Bradykinin; C | 1997 |
Evidence for alpha 2-adrenoceptor agonist activity of minoxidil.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Diethylstilbestrol; Female; Glybur | 1997 |
Glibenclamide sensitivity of neural relaxation of the rabbit sphincter of oddi.
Topics: Animals; Cyclic AMP; Cyclic GMP; Glyburide; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Sm | 1997 |
Ca2+-entry blockade by CAF603, a carotane sesquiterpene isolated from Trichoderma virens.
Topics: Animals; Calcium Channel Blockers; Glyburide; Guinea Pigs; In Vitro Techniques; Intestine, Small; Mu | 1997 |
KATP channels contribute to beta- and adenosine receptor-mediated pulmonary vasorelaxation.
Topics: Acetylcholine; Adenosine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Colforsin; | 1997 |
The effects of levcromakalim and pinacidil on the human internal mammary artery.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Apamin; Charybdotoxin; Coronary Artery Bypass; Coronary Dis | 1997 |
In vitro and in vivo vasodilating effects of KRN4884, Ki1769 and Ki3005, pyridinecarboxamidine derivatives.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Disease Models, Animal; Dose-Resp | 1997 |
Beta-adrenoceptor-mediated relaxation inhibited by tetrapentylammonium ions in rat mesenteric artery.
Topics: Adrenergic beta-Agonists; Animals; Fenoterol; Glyburide; In Vitro Techniques; Isoproterenol; Male; M | 1998 |
Mechanisms of relaxations of bovine isolated bronchioles by the nitric oxide donor, GEA 3175.
Topics: Albuterol; Aminoquinolines; Animals; Apamin; Bronchi; Bronchodilator Agents; Cattle; Charybdotoxin; | 1998 |
Evidence that different mechanisms underlie smooth muscle relaxation to nitric oxide and nitric oxide donors in the rabbit isolated carotid artery.
Topics: Acetylcholine; Animals; Apamin; Calcimycin; Carotid Arteries; Cell Membrane; Cyclic GMP; Glyburide; | 1998 |
The endothelium-dependent, substance P relaxation of porcine coronary arteries resistant to nitric oxide synthesis inhibition is partially mediated by 4-aminopyridine-sensitive voltage-dependent K+ channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Animals; Apamin | 1997 |
Activation of large-conductance potassium channels in pregnant human myometrium by pinacidil.
Topics: Calcium; Charybdotoxin; Electric Conductivity; Female; Glyburide; Guanidines; Humans; Muscle Relaxat | 1998 |
ATP-sensitive K+ channel blocker glibenclamide and diaphragm fatigue during normoxia and hypoxia.
Topics: Adenosine Triphosphate; Animals; Diaphragm; Electric Stimulation; Glyburide; Hypoglycemic Agents; Hy | 1998 |
Relaxation of corpus cavernosum and raised intracavernous pressure by berberine in rabbit.
Topics: 4-Aminopyridine; Animals; Apamin; Berberine; Charybdotoxin; Dose-Response Relationship, Drug; Endoth | 1998 |
Potassium channel activation and relaxation by nicorandil in rat small mesenteric arteries.
Topics: Aminoquinolines; Animals; Calcium Channels; Carbonyl Cyanide m-Chlorophenyl Hydrazone; Electrophysio | 1998 |
Comparison of the vascular relaxant effects of ATP-dependent K+ channel openers on aorta and pulmonary artery isolated from spontaneously hypertensive and Wistar-Kyoto rats.
Topics: Adenosine Triphosphate; Aminoquinolines; Animals; Aorta, Thoracic; Apamin; Benzopyrans; Charybdotoxi | 1999 |
Glibenclamide-sensitive K+ channels underlying levcromakalim-induced relaxation in pig urethra.
Topics: Animals; Cromakalim; Dose-Response Relationship, Drug; Female; Glyburide; In Vitro Techniques; Membr | 1999 |
Ginsenoside Rg3 mediates endothelium-dependent relaxation in response to ginsenosides in rat aorta: role of K+ channels.
Topics: Adrenergic beta-Antagonists; Animals; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Atropine; | 1999 |
The ginsenoside Rg3 evokes endothelium-independent relaxation in rat aortic rings: role of K+ channels.
Topics: Animals; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Calcium; Calcium Channel Blockers; Crom | 1999 |
Endothelium-derived relaxing, contracting and hyperpolarizing factors of mesenteric arteries of hypertensive and normotensive rats.
Topics: Acetylcholine; Animals; Apamin; Blood Pressure; Body Weight; Bridged Bicyclo Compounds, Heterocyclic | 1999 |
Role of potassium channels and nitric oxide in the relaxant effects elicited by beta-adrenoceptor agonists on hypoxic vasoconstriction in the isolated perfused lung of the rat.
Topics: Adrenergic beta-Agonists; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Glyburide; Hypoxia; | 1999 |
Cyclic GMP regulates cromakalim-induced relaxation in the rat aortic smooth muscle: role of cyclic GMP in K(ATP)-channels.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Apamin; Calcium; Charybdotoxin; Cromakalim; Cyclic | 1999 |
Increased nitroglycerin-induced relaxation by genistein in rat aortic rings.
Topics: Animals; Aorta; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; | 1999 |
Pharmacological characterization of metamizol-induced relaxation in phenylephrine-precontracted rabbit thoracic aorta smooth muscle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Dipyrone; Dose-Response Relations | 1999 |
Glycyrrhetinic acid-sensitive mechanism does not make a major contribution to non-prostanoid, non-nitric oxide mediated endothelium-dependent relaxation of rat mesenteric artery in response to acetylcholine.
Topics: Acetylcholine; Animals; Arachidonic Acid; Endothelium, Vascular; Enzyme Inhibitors; Epoprostenol; Gl | 1999 |
The mechanisms underlying the relaxant effect of methyl and ethyl gallates in the guinea pig trachea in vitro: contribution of potassium channels.
Topics: Animals; Charybdotoxin; Dose-Response Relationship, Drug; Epithelium; Female; Gallic Acid; Glyburide | 1999 |
Different mechanisms for testosterone-induced relaxation of aorta between normotensive and spontaneously hypertensive rats.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Aorta, Thoracic; Cyclooxygenase Inhibitors; Dose-Response R | 1999 |
Role of K+ channels in augmented relaxations to sodium nitroprusside induced by mexiletine in rat aortas.
Topics: Animals; Anti-Arrhythmia Agents; Aorta; Apamin; Drug Synergism; Glyburide; Hydrazines; In Vitro Tech | 2000 |
Atypical effect of minoxidil sulphate on guinea pig airways.
Topics: Adenosine Triphosphate; Animals; Antigen-Antibody Complex; Benzopyrans; Blood Pressure; Bronchial Hy | 2000 |
EDHF, NO and a prostanoid: hyperpolarization-dependent and -independent relaxation in guinea-pig arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Biological Fa | 2000 |
K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Cycli | 2000 |
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburi | 2000 |
The role of oxygen-derived free radicals in augmented relaxations to levcromakalim in the aorta from hypertensive rats.
Topics: Animals; Aorta; Blood Pressure; Catalase; Cromakalim; Deferoxamine; Dose-Response Relationship, Drug | 2001 |
Dual mechanism of action of nicorandil on rabbit corpus cavernosal smooth muscle tone.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Enzyme Activation; Enzyme Inhibitors; Gl | 2001 |
Antisense knockdown of inducible nitric oxide synthase inhibits the relaxant effect of VIP in isolated smooth muscle cells of the mouse gastric fundus.
Topics: Amidines; Animals; Arginine; Benzylamines; Carbachol; Cell Size; DNA, Antisense; Enzyme Inhibitors; | 2001 |
Characterization of adenosine action in isolated rat renal artery. Possible role of adenosine A(2A) receptors.
Topics: Adenosine; Animals; Caffeine; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Indomethacin; Iso | 2000 |
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response | 2001 |
The involvement of L-type Ca(2+) channels in the relaxant effects of the ATP-sensitive K(+) channel opener ZD6169 on pig urethral smooth muscle.
Topics: Adenosine Triphosphate; Amides; Animals; Barium; Benzophenones; Calcium Channel Blockers; Calcium Ch | 2001 |
The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Female; | 2002 |
Functional characterization of adenosine receptors and coupling to ATP-sensitive K+ channels in Guinea pig urinary bladder smooth muscle.
Topics: Adenosine; Adenosine Deaminase; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Glybu | 2002 |
One way cross tolerance between cromakalim and salbutamol in the uterus of the rat in vivo.
Topics: Albuterol; Animals; Benzopyrans; Cromakalim; Cyclic AMP; Drug Interactions; Drug Tolerance; Female; | 1992 |
Pharmacological interaction experiments differentiate between glibenclamide-sensitive K+ channels and cyclic GMP as components of vasodilation by nicorandil.
Topics: Animals; Benzopyrans; Cattle; Coronary Vessels; Cromakalim; Cyclic GMP; Drug Interactions; Glyburide | 1992 |
Effects of cromakalim on the contraction and the membrane potential of the circular smooth muscle of guinea-pig stomach.
Topics: Acetylcholine; Animals; Benzopyrans; Charybdotoxin; Cromakalim; Electric Stimulation; Glyburide; Gui | 1992 |
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Mechanisms of action of cicletanine in human and guinea pig resistance arteries.
Topics: Animals; Antihypertensive Agents; Arteries; Charybdotoxin; Diuretics; Drug Interactions; Eicosanoids | 1992 |
Comparison of the relaxing effects of cicletanine and cromakalim on vascular smooth muscle.
Topics: Animals; Antihypertensive Agents; Aorta; Benzopyrans; Cromakalim; Diuretics; Dose-Response Relations | 1992 |
Analysis of the relaxant action of SDZ PCO 400 in airway smooth muscle from the ox and guinea-pig.
Topics: Animals; Benzopyrans; Bretylium Compounds; Cattle; Cyclopentanes; Dose-Response Relationship, Drug; | 1992 |
Glibenclamide does not block arterial relaxation caused by vasoactive intestinal polypeptide.
Topics: Animals; Carbachol; Endothelium, Vascular; Female; Glyburide; Male; Mesenteric Arteries; Methylene B | 1992 |
Evidence that epithelium-dependent relaxation of vascular smooth muscle detected by co-axial bioassays is not attributable to hypoxia.
Topics: Animals; Aorta; Benzopyrans; Biological Assay; Biological Factors; Cromakalim; Epithelium; Glyburide | 1992 |
Comparison of the actions of acetylcholine and BRL 38227 in the guinea-pig coronary artery.
Topics: Acetylcholine; Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; | 1992 |
Differential inhibition by tedisamil (KC 8857) and glibenclamide of the responses to cromakalim and minoxidil sulphate in rat isolated aorta.
Topics: Animals; Aorta; Benzopyrans; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cro | 1992 |
Relaxant effects of BRL 38227 and pinacidil on the rat gastric fundus.
Topics: Animals; Benzopyrans; Cromakalim; Dose-Response Relationship, Drug; Female; Gastric Fundus; Glyburid | 1992 |
Inhibition of endothelium-dependent vasorelaxation by arginine analogues: a pharmacological analysis of agonist and tissue dependence.
Topics: Acetylcholine; Alkylation; Animals; Aorta, Thoracic; Arginine; Glyburide; In Vitro Techniques; Indom | 1992 |
Analysis of acetylcholine-induced relaxation of rabbit isolated middle cerebral artery: effects of inhibitors of nitric oxide synthesis, Na,K-ATPase, and ATP-sensitive K channels.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Cerebral Arteries; Glyburide; Male; Muscle | 1991 |
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin.
Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; | 1991 |
Selective inhibition of relaxation of guinea-pig trachea by charybdotoxin, a potent Ca(++)-activated K+ channel inhibitor.
Topics: Aminophylline; Animals; Benzopyrans; Calcium; Carbachol; Charybdotoxin; Cromakalim; Dose-Response Re | 1990 |
Effects of cromakalim, RP49356, diazoxide, glibenclamide and galanin in rat portal vein.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Diazoxide; Galanin; Glyburide; In Vitro Te | 1990 |
Heterogeneous involvement of endothelium in calcitonin gene-related peptide-induced relaxation in coronary arteries from rat.
Topics: Acetylcholine; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Coronary Vessels; Endothelium, V | 1991 |
ATP-sensitive potassium channels do not mediate vasorelaxation by acetylcholine or iloprost.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Electric S | 1991 |
Endothelium-dependent relaxation and hyperpolarization in aorta from control and renal hypertensive rats.
Topics: Acetylcholine; Animals; Aorta; Carbachol; Endothelium, Vascular; Glyburide; Hypertension, Renal; In | 1992 |
Actions of cromakalim in isolated human saphenous vein.
Topics: Antihypertensive Agents; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Humans; In Vitro Techniques; | 1992 |
NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea-pig isolated trachea.
Topics: Animals; Arachidonic Acid; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Guinea Pigs; Indomethacin; | 1991 |
Potassium channel opening properties of a novel compound, NIP-121, cromakalim and nicorandil in rat aorta and portal vein.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; In Vitro Tech | 1991 |
Chiral recognition of pinacidil and its 3-pyridyl isomer by canine cardiac and smooth muscle: antagonism by sulfonylureas.
Topics: Adenosine Triphosphate; Animals; Dogs; Dose-Response Relationship, Drug; Female; Glipizide; Glyburid | 1991 |
RP 49356 and cromakalim relax airway smooth muscle in vitro by opening a sulphonylurea-sensitive K+ channel: a comparison with nifedipine.
Topics: Animals; Benzopyrans; Calcium; Cromakalim; Glipizide; Glyburide; Guinea Pigs; In Vitro Techniques; M | 1991 |
Inhibition of the acetylcholine-induced relaxation of canine isolated basilar artery by potassium-conductance blockers.
Topics: 4-Aminopyridine; Acetylcholine; Animals; Barium; Basilar Artery; Dogs; Female; Glyburide; In Vitro T | 1991 |
Glibenclamide blocks the relaxant action of pinacidil and cromakalim in airway smooth muscle.
Topics: Animals; Benzopyrans; Cromakalim; Female; Glyburide; Guanidines; Guinea Pigs; Histamine; In Vitro Te | 1990 |
Evidence that pinacidil may promote the opening of ATP-sensitive K+ channels yet inhibit the opening of Ca2(+)-activated K+ channels in K(+)-contracted canine mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Dogs; Female; Glyburide; Guanidin | 1990 |
Hypoglycemic sulfonylureas antagonize the effects of cromakalim and pinacidil on 86Rb fluxes and contractile activity in the rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; Guanidines; Hypoglycemic Agents; In Vi | 1990 |
Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Coronary Vessels; Cromakalim; Cytoplasm; Dogs | 1990 |
Inhibition by glibenclamide of the vasorelaxant action of cromakalim in the rat.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Blood Pressure; Cromakalim; Glyburide; Heart Rate; In Vitro T | 1989 |
Cromakalim-induced relaxation of guinea-pig isolated trachealis: antagonism by glibenclamide and by phentolamine.
Topics: Animals; Benzopyrans; Cromakalim; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro Techni | 1989 |
Effects of glibenclamide on cromakalim-induced responses in rabbit isolated aorta.
Topics: Animals; Aorta; Benzopyrans; Cromakalim; Drug Interactions; Glyburide; In Vitro Techniques; Male; Mu | 1989 |
Glibenclamide and procaine, but not apamin, inhibit the relaxant responses to Ro 31-6930 in guinea-pig taenia caeci.
Topics: Animals; Apamin; Bee Venoms; Benzopyrans; Cecum; Colon; Female; Glyburide; Guinea Pigs; In Vitro Tec | 1989 |
Glibenclamide is a competitive antagonist of cromakalim, pinacidil and RP 49356 in guinea-pig pulmonary artery.
Topics: Animals; Benzopyrans; Cromakalim; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Met | 1989 |
[Importance of calcium in the interaction between prostaglandins E and sulfonylureas in utero].
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Drug Interactions; Female; Glyburide; Muscle Rel | 1986 |