glyburide has been researched along with Muscle Contraction in 211 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 5.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "(1) Emodin inhibited the tension and amplitude of jejunum smooth muscle contraction in a dose-dependent manner (P < 0." | 3.80 | [The effect of emodin on the contraction of isolated jejunum smooth muscle of rats]. ( Gao, L; Guo, Z; Han, X; Hu, P; Jiang, LL; Ma, HJ; Yang, J; Zhang, Y, 2014) |
| " Arcade arteriolar diameters were measured following muscle contraction or application of the KATP opener cromakalim before and after glibenclamide application." | 3.79 | Impaired vascular KATP function attenuates exercise capacity in obese zucker rats. ( Clemmer, JS; Gowdey, AR; Hester, RL; Lu, S; Mittwede, PN; Xiang, L, 2013) |
| " We have previously demonstrated that mesenteric lymphatic pumping was compromised in the guinea pig model of 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced ileitis, corroborating clinical and experimental observations of a dilated and/or obstructed phenotype of these vessels in inflammatory bowel disease." | 3.79 | Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis. ( Mathias, R; von der Weid, PY, 2013) |
| "In this study we have evaluated the cough reflex inhibiting potential and modulation of ASM reactivity in vitro, by K+ATP opener-pinacidil in guinea pig and cats." | 3.75 | The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways. ( Franova, S; Sutovska, M; Sutovsky, J, 2009) |
| " The aim of this work was to investigate MZ effects on angiotensin II (AT II) and noradrenaline (NA) induced contraction and to evaluate the K participation on MZ modulating effect on vascular smooth muscle contraction, using isometric and patch clamp techniques." | 3.73 | Metamizol acts as an ATP sensitive potassium channel opener to inhibit the contracting response induced by angiotensin II but not to norepinephrine in rat thoracic aorta smooth muscle. ( García-Saisó, S; Lemini, C; Mendoza-Fernández, V; Ramírez-Solares, R; Valenzuela, F; Vidrio, H, 2005) |
| "To determine whether nitric oxide (NO), adenosine (Ado) receptors, or ATP-sensitive potassium (K(ATP)) channels play a role in arteriolar dilations induced by muscle contraction, we used a cremaster preparation in anesthetized hamsters in which we stimulated four to five muscle fibers lying perpendicular to a transverse arteriole (maximal diameter approximately 35-65 microm)." | 3.71 | Multiple dilator pathways in skeletal muscle contraction-induced arteriolar dilations. ( Murrant, CL; Sarelius, IH, 2002) |
| "We investigated whether the adenosine triphosphate (ATP)-sensitive K+ (K(ATP)) channel activation by bimakalim, at concentrations devoid of both negative inotropic and action-potential duration (APD) shortening effects, might exhibit myocardial protection after hypoxia and reoxygenation in human atrial myocardium by using 112 preparations." | 3.70 | Protection of human myocardium in vitro by K(ATP) activation with low concentrations of bimakalim. ( Criniti, A; del Monte, F; Ducouret, P; Iwashiro, K; Monti, F; Papalia, U; Picard, S; Puddu, PE; Rouet, R; Ruvolo, G; Tonelli, E, 1999) |
| " Spontaneous detrusor muscle contractions were unaffected by glibenclamide (K(ATP) channel blocker) but were reduced when pinacidil (K(ATP) channel opener) concentrations exceeded 10(-5) M." | 3.70 | K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle. ( Elliott, RA; Hudman, D; Norman, RI, 2000) |
| "Glibenclamide, iberiotoxin, and apamin (blockers of ATP-sensitive, large-conductance, and small-conductance Ca(2+)-activated K+ channels, respectively) were infused into the diaphragmatic vasculature of anesthetized indomethacin-treated dogs to assess the contribution of K+ channels to active hyperemia." | 3.69 | Contribution of potassium channels to active hyperemia of the canine diaphragm. ( Chang, HY; Gatensby, AG; Hussain, SN; Vanelli, G, 1994) |
| ", cromakalim, pinacidil) are potent relaxants of smooth muscle, their utility for treating myocardial ischemia may be limited by hypotension." | 3.69 | Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448. ( Atwal, KS; D'Alonzo, AJ; Grover, GJ; McCullough, JR; Sargent, CA, 1995) |
| "The present study investigated the mechanisms of melatonin-induced inhibition of the ileal smooth muscle contraction." | 3.69 | Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle. ( García-Segoviano, JA; Naranjo-Rodríguez, EB; Prieto-Gómez, B; Reyes-Vázquez, C; Trujillo-Santana, JT, 1997) |
| "Hydrogen sulfide is an endogenous gasotransmitter and its mechanism of action involves activation of ATP-sensitive K(+) channels and phosphodiesterase inhibition." | 1.43 | Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia. ( Andria, B; Attanasio, C; Bucci, M; Calderone, V; Cantalupo, A; Cirino, G; Di Martino, A; Ianaro, A; Mancini, A; Panza, E; Savoia, G; Vellecco, V, 2016) |
| "Pre-treatment with methysergide reduced and increased the contractile responses to 5-HT and EFS, respectively." | 1.40 | The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinus. ( Javid, FA; Palea, S, 2014) |
| "Lactic acid treatment elevated interstitial ATP of buffer-perfused muscle and extracellular ATP of L6 myocytes: this ATP release was abolished by the non-specific CFTR inhibitor, glibenclamide, or the specific CFTR inhibitor, CFTR(inh)-172, suggesting that CFTR was involved, and by inhibition of lactic acid entry to cells, indicating that intracellular pH depression was required." | 1.38 | cAMP/protein kinase A activates cystic fibrosis transmembrane conductance regulator for ATP release from rat skeletal muscle during low pH or contractions. ( Ballard, HJ; Cai, W; Lu, L; Tu, J, 2012) |
| "Caffeine is known to inhibit cyclic nucleotide phosphodiesterases (PDEs), leading to an increase in cytosolic cAMP and stimulation of downstream cAMP-dependent mechanisms." | 1.37 | Inhibitory effect of caffeine on pacemaker activity in the oviduct is mediated by cAMP-regulated conductances. ( Britton, F; Dixon, R; Hwang, S; Sanders, K; Ward, S, 2011) |
| "Pretreatment with nifedipine attenuated anemoside A(3)-induced relaxation." | 1.36 | Anemoside A3-induced relaxation in rat renal arteries: role of endothelium and Ca2+ channel inhibition. ( Fan, CL; Huang, Y; Lau, CW; Li, Y; Lin, SM; Wang, J; Ye, WC; Yiu, A; Zhang, DM, 2010) |
| "3 x 10(-3) mol/L) produced a significant rightward shift in the phenylephrine dose-response curve, but had no effects on the potassium chloride-induced contraction." | 1.35 | Relaxant effects of matrine on aortic smooth muscles of guinea pigs. ( Dai, GD; Fu, XY; Yan, L; Zheng, J; Zheng, P; Zhou, R; Zhou, X, 2009) |
| "Pretreatment with lithium chloride at the threshold concentrations enhanced the inhibitory effects of verapamil on diaphragmatic contractions elicited either indirectly or directly." | 1.31 | The myoneural effects of lithium chloride on the nerve-muscle preparations of rats. Role of adenosine triphosphate-sensitive potassium channels. ( Abdel-Zaher, AO, 2000) |
| "Sevoflurane responses were repeated at concentrations with no effect on spontaneous contractility of TEA, a Ca(2+)-activated K(+) channel blocker, and glibenclamide, an adenosine triphosphate-sensitive K(+) channel blocker, in myometrial strips." | 1.31 | The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium. ( Bagcivan, I; Gürsoy, S; Kafali, H; Karadas, B; Kaya, T; Sarioglu, Y, 2002) |
| "Tamoxifen is a highly potent inhibitor of the contractile activity of the human nonpregnant myometrium and uterine arteries." | 1.30 | Potent inhibition by tamoxifen of spontaneous and agonist-induced contractions of the human myometrium and intramyometrial arteries. ( Batra, S; Kostrzewska, A; Laudañski, T, 1997) |
| "Pretreatment with tetrodotoxin (TTX) (3-10 microM) or N(G)-nitro-L-arginine (100 microM) had little effect on the spontaneous contractility of the UUT, motility indexes (MIs) (contraction amplitude x contraction frequency) calculated after 20 min exposure were little affected by TTX or N(G)-nitro-L-arginine (L-NOARG)." | 1.30 | Stretch-evoked inhibition of spontaneous migrating contractions in a whole mount preparation of the guinea-pig upper urinary tract. ( Lang, RJ; Teele, ME, 1998) |
| " However, the inhibition of the combined CPA and CCh response was reduced and the dose-response curve of SIN-1 shifted to the right." | 1.30 | Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP. ( Allescher, HD; Franck, H; Puschmann, A; Schusdziarra, V; Storr, M, 1998) |
| "Adenosine has previously been shown to stimulate K(+)-efflux and to block L-type calcium channels in atrial myocytes." | 1.30 | Effects of K(+)-channel blockers on A1-adenosine receptor-mediated negative inotropy and chronotropy of guinea-pig isolated left and right atria. ( Broadley, KJ; Ford, WR, 1999) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 1.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "Indapamide was a far more potent inhibitor, a 10 microM concentration shifting the calcium dose-response curve 3 log units to the right and reducing maximal calcium contraction by 72% (P < ." | 1.29 | Ion channel involvement in the acute vascular effects of thiazide diuretics and related compounds. ( Calder, JA; Schachter, M; Sever, PS, 1993) |
| "Cromakalim effects were studied in rabbit aortic rings contracted by stimuli corresponding to the above mechanisms." | 1.29 | Cromakalim inhibits multiple mechanisms of smooth muscle activation with similar stereoselectivity. ( Groschner, K; Kühberger, E; Kukovetz, WR, 1993) |
| "Pretreatment with diazoxide (10 mg." | 1.29 | Effects of diazoxide on norepinephrine-induced vasocontraction and ischemic myocardium in rats. ( Ichihara, K; Nakai, T, 1994) |
| " In conclusion, isolated mesenteric arteries from obese Zucker rats do not show relevant structural changes, and the pharmacodynamic behaviour of such vessels appears to be the same as that of control preparations." | 1.29 | Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats. ( Kam, KL; Pfaffendorf, M; van Zwieten, PA, 1996) |
| "Cromakalim was less effective against the 25." | 1.28 | Effects of cromakalim on the contraction and the membrane potential of the circular smooth muscle of guinea-pig stomach. ( Asano, M; Ito, K; Kanno, T; Masuzawa-Ito, K; Ohashi, H; Suzuki, H; Suzuki, K; Takewaki, T, 1992) |
| "Fraxinellone and verapamil were more potent and effective in producing relaxation in 60 mmol/l than in 15 mmol/l K(+)-induced contraction." | 1.28 | Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers. ( Huang, TF; Ko, FN; Su, MJ; Teng, CM; Wang, ML; Wu, TS; Yu, SM, 1992) |
| "Cromakalim has been shown to inhibit naphazoline-induced contractions and spontaneous activity induced by exposure to naphazoline in the rat isolated vas deferens." | 1.28 | Inhibition by glibenclamide of the effects of cromakalim on responses of rat vas deferens to naphazoline. ( Barbieri, A; Grana, E; Zonta, F, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (1.90) | 18.7374 |
| 1990's | 132 (62.56) | 18.2507 |
| 2000's | 49 (23.22) | 29.6817 |
| 2010's | 23 (10.90) | 24.3611 |
| 2020's | 3 (1.42) | 2.80 |
| Authors | Studies |
|---|---|
| Malysz, J | 2 |
| Maxwell, SE | 2 |
| Yarotskyy, V | 1 |
| Petkov, GV | 3 |
| Britto-Júnior, J | 1 |
| Jacintho, FF | 1 |
| Figueiredo Murari, GM | 1 |
| Campos, R | 1 |
| Moreno, RA | 1 |
| Antunes, E | 1 |
| Mónica, FZ | 1 |
| De Nucci, G | 1 |
| Leo, MD | 1 |
| Horii, K | 1 |
| Suzuki, Y | 2 |
| Shiina, T | 1 |
| Saito, S | 1 |
| Onouchi, S | 1 |
| Horii, Y | 1 |
| Shimaoka, H | 1 |
| Shimizu, Y | 1 |
| Lu, S | 1 |
| Xiang, L | 1 |
| Clemmer, JS | 1 |
| Gowdey, AR | 1 |
| Mittwede, PN | 1 |
| Hester, RL | 1 |
| Javid, FA | 1 |
| Palea, S | 1 |
| Hu, P | 1 |
| Yang, J | 1 |
| Gao, L | 1 |
| Han, X | 1 |
| Jiang, LL | 1 |
| Ma, HJ | 1 |
| Guo, Z | 1 |
| Zhang, Y | 2 |
| Saidullah, B | 1 |
| Muralidhar, K | 1 |
| Fahim, M | 1 |
| Vasconcelos, LH | 1 |
| Correia, AC | 1 |
| de Souza, IL | 1 |
| Silva, Mda C | 1 |
| Paredes-Gamero, EJ | 1 |
| Santos, BV | 1 |
| Cavalcante, Fde A | 1 |
| da Silva, BA | 1 |
| Vellecco, V | 1 |
| Mancini, A | 1 |
| Ianaro, A | 1 |
| Calderone, V | 1 |
| Attanasio, C | 1 |
| Cantalupo, A | 1 |
| Andria, B | 1 |
| Savoia, G | 1 |
| Panza, E | 1 |
| Di Martino, A | 1 |
| Cirino, G | 1 |
| Bucci, M | 1 |
| Holdsworth, CT | 1 |
| Ferguson, SK | 1 |
| Poole, DC | 1 |
| Musch, TI | 1 |
| Shimbo, T | 1 |
| Adachi, T | 1 |
| Fujisawa, S | 1 |
| Hongoh, M | 1 |
| Ohba, T | 1 |
| Ono, K | 1 |
| Yuan, YW | 1 |
| Wang, L | 1 |
| Lu, ZY | 1 |
| Long, Y | 1 |
| Jiao, YF | 1 |
| Xia, Q | 1 |
| Wen, DX | 1 |
| Yu, WF | 1 |
| Khin, PP | 1 |
| Zaw, TS | 1 |
| Sohn, UD | 1 |
| Li, J | 1 |
| Gao, Z | 1 |
| Kehoe, V | 1 |
| Xing, J | 1 |
| King, N | 1 |
| Sinoway, L | 1 |
| Cifelli, C | 2 |
| Boudreault, L | 1 |
| Gong, B | 1 |
| Bercier, JP | 1 |
| Renaud, JM | 7 |
| Faruqui, AR | 1 |
| Mathai, J | 1 |
| George, J | 1 |
| Peedicayil, J | 1 |
| Ernest, K | 1 |
| Neelakantan, N | 1 |
| Shirozu, K | 1 |
| Akata, T | 2 |
| Yoshino, J | 1 |
| Setoguchi, H | 1 |
| Morikawa, K | 1 |
| Hoka, S | 1 |
| Mukohda, M | 1 |
| Yamawaki, H | 1 |
| Nomura, H | 1 |
| Okada, M | 1 |
| Hara, Y | 1 |
| Sutovska, M | 1 |
| Franova, S | 1 |
| Sutovsky, J | 1 |
| Zheng, J | 1 |
| Zheng, P | 1 |
| Zhou, X | 1 |
| Yan, L | 1 |
| Zhou, R | 1 |
| Fu, XY | 1 |
| Dai, GD | 1 |
| Ohmasa, F | 1 |
| Saito, M | 2 |
| Shimizu, S | 1 |
| Taniguchi, S | 1 |
| Dimitriadis, F | 1 |
| Satoh, I | 1 |
| Kinoshita, Y | 1 |
| Satoh, K | 3 |
| Sordi, R | 1 |
| Fernandes, D | 1 |
| Assreuy, J | 1 |
| Zhang, DM | 1 |
| Lin, SM | 1 |
| Lau, CW | 4 |
| Yiu, A | 1 |
| Wang, J | 1 |
| Li, Y | 1 |
| Fan, CL | 1 |
| Huang, Y | 5 |
| Ye, WC | 1 |
| Lobov, GI | 2 |
| Pan'kova, MN | 1 |
| Medina, P | 1 |
| Segarra, G | 1 |
| Mauricio, MD | 1 |
| Vila, JM | 1 |
| Chuan, P | 1 |
| Lluch, S | 1 |
| Andrade, F | 1 |
| Trujillo, X | 1 |
| Sánchez-Pastor, E | 1 |
| Montoya-Pérez, R | 1 |
| Saavedra-Molina, A | 1 |
| Ortiz-Mesina, M | 1 |
| Huerta, M | 1 |
| Oger, S | 1 |
| Behr-Roussel, D | 1 |
| Gorny, D | 1 |
| Bernabé, J | 1 |
| Comperat, E | 1 |
| Chartier-Kastler, E | 1 |
| Denys, P | 1 |
| Giuliano, F | 1 |
| Dixon, R | 1 |
| Hwang, S | 1 |
| Britton, F | 1 |
| Sanders, K | 1 |
| Ward, S | 1 |
| Semenykhina, OM | 1 |
| Baziliuk, OV | 1 |
| Korkach, IuP | 1 |
| Sahach, VF | 1 |
| Yamauchi, K | 1 |
| Stone, AJ | 1 |
| Stocker, SD | 1 |
| Kaufman, MP | 1 |
| Tu, J | 1 |
| Lu, L | 1 |
| Cai, W | 1 |
| Ballard, HJ | 2 |
| Mathias, R | 1 |
| von der Weid, PY | 2 |
| Weiss, R | 1 |
| Mevissen, M | 1 |
| Hauser, DS | 1 |
| Scholtysik, G | 1 |
| Portier, CJ | 1 |
| Walter, B | 1 |
| Studer, UE | 1 |
| Danuser, H | 1 |
| Zhao, KS | 1 |
| Huang, X | 1 |
| Liu, J | 1 |
| Huang, Q | 1 |
| Jin, C | 1 |
| Jiang, Y | 1 |
| Jin, J | 1 |
| Zhao, G | 1 |
| Kito, Y | 1 |
| Suzuki, H | 2 |
| Chan, AK | 1 |
| Sanz, E | 1 |
| Fernández, N | 1 |
| Monge, L | 1 |
| Climent, B | 1 |
| Diéguez, G | 1 |
| García-Villalón, AL | 1 |
| Tep-areenan, P | 1 |
| Kendall, DA | 1 |
| Randall, MD | 1 |
| Bruce, J | 1 |
| Taggart, M | 1 |
| Austin, C | 1 |
| Glavind-Kristensen, M | 1 |
| Matchkov, V | 1 |
| Hansen, VB | 1 |
| Forman, A | 1 |
| Nilsson, H | 2 |
| Aalkjaer, C | 1 |
| Hong, SJ | 2 |
| Liang, HC | 1 |
| Shen, CJ | 1 |
| Quilley, J | 1 |
| Qiu, Y | 1 |
| Mo, FM | 1 |
| Valenzuela, F | 1 |
| García-Saisó, S | 1 |
| Lemini, C | 1 |
| Ramírez-Solares, R | 1 |
| Vidrio, H | 1 |
| Mendoza-Fernández, V | 1 |
| Gilani, AH | 3 |
| Khan, AU | 3 |
| Jabeen, Q | 1 |
| Subhan, F | 1 |
| Ghafar, R | 1 |
| Zhang, HY | 1 |
| Xu, CQ | 1 |
| Li, HZ | 1 |
| Li, BX | 1 |
| Zhang, YQ | 1 |
| Zhang, YN | 1 |
| Sathishkumar, K | 1 |
| Ross, GR | 1 |
| Prakash, VR | 1 |
| Mishra, SK | 1 |
| Ghayur, MN | 1 |
| Ali, SF | 1 |
| Herzig, JW | 1 |
| Kubo, S | 2 |
| Doe, I | 1 |
| Kurokawa, Y | 1 |
| Nishikawa, H | 1 |
| Kawabata, A | 2 |
| Xu, JY | 1 |
| Song, Y | 1 |
| Ji, H | 1 |
| Vijayakumar, C | 1 |
| Kathirvel, K | 1 |
| Sardar, KK | 1 |
| Parija, SC | 1 |
| Broch-Lips, M | 1 |
| Overgaard, K | 1 |
| Praetorius, HA | 1 |
| Nielsen, OB | 1 |
| Bourassa, F | 1 |
| Gariépy, L | 1 |
| Banas, K | 1 |
| Benkhalti, M | 1 |
| Dutka, TL | 1 |
| Lamb, GD | 1 |
| Novakovic, R | 1 |
| Milovanovic, S | 1 |
| Protic, D | 1 |
| Djokic, J | 1 |
| Heinle, H | 1 |
| Gojkovic-Bukarica, L | 1 |
| Kajiwara, M | 1 |
| Balwierczak, JL | 1 |
| Krulan, CM | 1 |
| Kim, HS | 1 |
| DelGrande, D | 1 |
| Weiss, GB | 1 |
| Hu, S | 1 |
| Lang, RJ | 2 |
| Asano, M | 4 |
| Masuzawa-Ito, K | 3 |
| Matsuda, T | 3 |
| Oyama, H | 1 |
| Shibuya, M | 1 |
| Sugita, K | 1 |
| Bauer, JA | 1 |
| Fung, HL | 1 |
| Zheng, W | 1 |
| Kwon, YW | 1 |
| Gopalakrishnan, M | 1 |
| Triggle, DJ | 1 |
| Kanwal, S | 1 |
| Trachte, GJ | 1 |
| Abrahams, Z | 1 |
| Sutter, MC | 1 |
| Vanelli, G | 1 |
| Chang, HY | 1 |
| Gatensby, AG | 1 |
| Hussain, SN | 1 |
| Franck, H | 2 |
| Puschmann, A | 2 |
| Schusdziarra, V | 2 |
| Allescher, HD | 2 |
| Meini, S | 1 |
| Santicioli, P | 6 |
| Maggi, CA | 6 |
| Ishibashi, T | 1 |
| Kawada, T | 1 |
| Kato, K | 1 |
| Hamaguchi, M | 1 |
| Imai, S | 1 |
| Duty, S | 1 |
| Allen, DG | 1 |
| Yokoyama, T | 1 |
| Kasai, H | 1 |
| Okada, Y | 2 |
| Izumi, H | 1 |
| Izawa, T | 1 |
| Ogawa, N | 1 |
| Trivedi, S | 1 |
| Potter-Lee, L | 1 |
| McConville, MW | 1 |
| Li, JH | 1 |
| Ohnmacht, CJ | 1 |
| Trainor, DA | 1 |
| Kau, ST | 1 |
| Laurent, F | 2 |
| Michel, A | 3 |
| Bonnet, PA | 2 |
| Chapat, JP | 1 |
| Boucard, M | 2 |
| Calder, JA | 2 |
| Schachter, M | 2 |
| Sever, PS | 2 |
| Kühberger, E | 1 |
| Kukovetz, WR | 1 |
| Groschner, K | 1 |
| Kontani, H | 1 |
| Ginkawa, M | 1 |
| Sakai, T | 1 |
| Grover, GJ | 2 |
| McCullough, JR | 1 |
| D'Alonzo, AJ | 1 |
| Sargent, CA | 1 |
| Atwal, KS | 2 |
| Zhang, H | 3 |
| Bolton, TB | 1 |
| Yamashita, T | 1 |
| Masuda, Y | 1 |
| Tanaka, S | 2 |
| Hatake, K | 1 |
| Wakabayashi, I | 1 |
| Hishida, S | 1 |
| Schilling, L | 1 |
| Parsons, AA | 1 |
| Wahl, M | 1 |
| Duncker, DJ | 1 |
| van Zon, NS | 1 |
| Pavek, TJ | 1 |
| Herrlinger, SK | 1 |
| Bache, RJ | 1 |
| Kline, LW | 2 |
| Pang, PK | 2 |
| Plane, F | 1 |
| Garland, CJ | 1 |
| Giuliani, S | 4 |
| Nakai, T | 1 |
| Ichihara, K | 1 |
| Comtois, A | 2 |
| Sinderby, C | 1 |
| Comtois, N | 1 |
| Grassino, A | 1 |
| Yu, SM | 2 |
| Lee, SS | 1 |
| Hou, YS | 1 |
| Teng, CM | 2 |
| Light, PE | 1 |
| Comtois, AS | 1 |
| Wang, GS | 1 |
| Li, YS | 1 |
| Fu, SX | 1 |
| Bishop, BE | 1 |
| Doggrell, SA | 1 |
| Matsumoto, K | 1 |
| Aizawa, H | 1 |
| Inoue, R | 1 |
| Hamano, S | 1 |
| Ikeda, S | 1 |
| Xie, Z | 1 |
| Hirata, M | 1 |
| Hara, N | 1 |
| Ito, Y | 1 |
| Kim, KW | 2 |
| Kim, SJ | 2 |
| Jun, JY | 2 |
| Light, P | 1 |
| Kong, M | 1 |
| Weselcouch, EO | 1 |
| Sargent, C | 1 |
| Wilde, MW | 1 |
| Smith, MA | 1 |
| Chang, CC | 1 |
| Findlay, I | 2 |
| Kamei, K | 1 |
| Nabata, H | 1 |
| Kuriyama, H | 2 |
| Katayama, N | 1 |
| Huang, SM | 1 |
| Tomita, T | 1 |
| Brading, AF | 2 |
| Orito, K | 1 |
| Taira, N | 4 |
| Savineau, JP | 1 |
| Marthan, R | 1 |
| de Moura, RS | 3 |
| de Mello, RF | 1 |
| D'Aguinaga, S | 1 |
| Sugimoto, S | 1 |
| Puddu, PE | 2 |
| Monti, F | 2 |
| Dawodu, AA | 1 |
| del Monte, F | 2 |
| Schiariti, M | 1 |
| Campa, PP | 1 |
| Marino, B | 1 |
| Sadraei, H | 1 |
| Beech, DJ | 1 |
| Fosset, M | 1 |
| Allard, B | 1 |
| Lazdunski, M | 1 |
| de Lemos Neto, M | 1 |
| Davies, MP | 1 |
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1 review available for glyburide and Muscle Contraction
| Article | Year |
|---|---|
Effects of glibenclamide upon ATP-sensitive K channels during metabolic inhibition of isolated rat cardiac myocytes.
Topics: Adenosine Triphosphate; Animals; Dinitrophenols; Electrophysiology; Glyburide; Heart Ventricles; In | 1993 |
210 other studies available for glyburide and Muscle Contraction
| Article | Year |
|---|---|
TRPM4 channel inhibitors 9-phenanthrol and glibenclamide differentially decrease guinea pig detrusor smooth muscle whole-cell cation currents and phasic contractions.
Topics: Animals; Cations; Cell Membrane; Glyburide; Guinea Pigs; Male; Membrane Potentials; Muscle Contracti | 2020 |
Electrical field stimulation induces endothelium-dependent contraction of human umbilical cord vessels.
Topics: Adult; Atropine; Blood Vessels; Electric Stimulation; Glyburide; Humans; Indomethacin; Muscle Contra | 2020 |
Age-dependent decrease in TRPM4 channel expression but not trafficking alters urinary bladder smooth muscle contractility.
Topics: Age Factors; Animals; Down-Regulation; Glyburide; Guinea Pigs; Male; Muscle Contraction; Muscle, Smo | 2021 |
ATP-dependent potassium channels contribute to motor regulation of esophageal striated muscle in rats.
Topics: Adenosine Triphosphate; Animals; Electric Stimulation; Esophagus; Glyburide; Male; Minoxidil; Muscle | 2019 |
Impaired vascular KATP function attenuates exercise capacity in obese zucker rats.
Topics: Acetophenones; Animals; Cromakalim; Enzyme Inhibitors; Glyburide; Humans; Hypoglycemic Agents; Male; | 2013 |
The effect of 5-HT and electrical field stimulation on the contractility of the whole isolated urinary bladder of Suncus murinus.
Topics: Adenosine Triphosphate; Animals; Atropine; Cromakalim; Electric Stimulation; Female; Glyburide; Male | 2014 |
[The effect of emodin on the contraction of isolated jejunum smooth muscle of rats].
Topics: Animals; Calcium Signaling; Emodin; Glyburide; Jejunum; Muscle Contraction; Muscle, Smooth; NG-Nitro | 2014 |
Onset of diabetes modulates the airway smooth muscle reactivity of guinea pigs: role of epithelial mediators.
Topics: Acetylcholine; Animals; Bronchi; Bronchoconstriction; Cyclooxygenase Inhibitors; Diabetes Mellitus, | 2014 |
Flavonoid galetin 3,6-dimethyl ether attenuates guinea pig ileum contraction through K(+) channel activation and decrease in cytosolic calcium concentration.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 2015 |
Cystathionine β-synthase-derived hydrogen sulfide is involved in human malignant hyperthermia.
Topics: Biopsy; Caffeine; Case-Control Studies; Cystathionine beta-Synthase; Dose-Response Relationship, Dru | 2016 |
Modulation of rat skeletal muscle microvascular O2 pressure via KATP channel inhibition following the onset of contractions.
Topics: Animals; Glyburide; Hemodynamics; KATP Channels; Male; Microvessels; Muscle Contraction; Muscle, Ske | 2016 |
In vitro effect of nicorandil on the carbachol-induced contraction of the lower esophageal sphincter of the rat.
Topics: Animals; Carbachol; Diazoxide; Dose-Response Relationship, Drug; Esophageal Sphincter, Lower; Glybur | 2016 |
Overexcited MaxiK and K
Topics: Action Potentials; Animals; Bilirubin; Charybdotoxin; Glyburide; In Vitro Techniques; Jaundice, Obst | 2016 |
Signal Transduction Underlying the Inhibitory Mechanism of Fluoxetine on Electrical Field Stimulation Response in Rat Ileal Smooth Muscle.
Topics: 4-Aminopyridine; Amides; Animals; Atropine; Azepines; Benzophenanthridines; Bicuculline; Calcimycin; | 2017 |
Interstitial adenosine triphosphate modulates muscle afferent nerve-mediated pressor reflex.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brefeldin A; Cats; Gadolinium; Glyburide; Heart Rat | 2008 |
Contractile dysfunctions in ATP-dependent K+ channel-deficient mouse muscle during fatigue involve excessive depolarization and Ca2+ influx through L-type Ca2+ channels.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Dose-Response Relationship, Dr | 2008 |
Inhibitory effect of nicorandil on the contraction of isolated human urinary bladder detrusor muscle.
Topics: Child; Child, Preschool; Electromyography; Female; Glyburide; Humans; Hypoglycemic Agents; In Vitro | 2008 |
The mechanisms of the direct action of etomidate on vascular reactivity in rat mesenteric resistance arteries.
Topics: Anesthetics, Intravenous; Animals; Calcium; Calcium Signaling; Dose-Response Relationship, Drug; End | 2009 |
Methylglyoxal inhibits smooth muscle contraction in isolated blood vessels.
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Glyburide; In Vitro Techniques; Male; Me | 2009 |
The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways.
Topics: Animals; Antitussive Agents; Cats; Citric Acid; Cough; Female; Glyburide; Guinea Pigs; KATP Channels | 2009 |
Relaxant effects of matrine on aortic smooth muscles of guinea pigs.
Topics: Alkaloids; Animals; Aorta; Calcium; Culture Media; Dose-Response Relationship, Drug; Glyburide; Guin | 2009 |
The role of ATP-sensitive potassium channel on acute urinary retention and subsequent catheterization in the rat.
Topics: Animals; Blood Circulation; Blood Pressure; Cromakalim; Dose-Response Relationship, Drug; Female; Gl | 2010 |
Differential involvement of potassium channel subtypes in early and late sepsis-induced hyporesponsiveness to vasoconstrictors.
Topics: 4-Aminopyridine; Animals; Apamin; Blood Pressure; Female; Glyburide; Muscle Contraction; Muscle, Smo | 2010 |
Anemoside A3-induced relaxation in rat renal arteries: role of endothelium and Ca2+ channel inhibition.
Topics: Animals; Apamin; Arteries; Biological Factors; Calcium; Calcium Channel Blockers; Capsaicin; Charybd | 2010 |
[NO-dependent. Modulation of contractile function in capsule of lymph nodes].
Topics: Acetylcholine; Animals; Cattle; Cholinergic Agents; Dose-Response Relationship, Drug; Endothelium, L | 2010 |
Modulation of adrenergic responses of human vas deferens by K+ channel inhibitors.
Topics: Adult; Apamin; Calcium; Calcium Channels, L-Type; Charybdotoxin; Electric Stimulation; Glyburide; Hu | 2010 |
Glibenclamide increases post-fatigue tension in slow skeletal muscle fibers of the chicken.
Topics: Animals; Caffeine; Calcium; Chickens; Cyanides; Electric Stimulation; Glyburide; Muscle Contraction; | 2011 |
Effects of potassium channel modulators on myogenic spontaneous phasic contractile activity in human detrusor from neurogenic patients.
Topics: Action Potentials; Adult; Aged; Apamin; Benzimidazoles; Case-Control Studies; Glyburide; Humans; In | 2011 |
Inhibitory effect of caffeine on pacemaker activity in the oviduct is mediated by cAMP-regulated conductances.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Animals; ATP-Binding Cassette Transporters; Biologic | 2011 |
[The effect of hydrogen sulfide on contractile activity of the vascular smooth muscles in rats].
Topics: Animals; Aorta, Thoracic; Cysteine; Dose-Response Relationship, Drug; Endothelium, Vascular; Glyburi | 2011 |
Blockade of ATP-sensitive potassium channels prevents the attenuation of the exercise pressor reflex by tempol in rats with ligated femoral arteries.
Topics: Animals; Blood Pressure; Blotting, Western; Cyclic N-Oxides; Decerebrate State; Femoral Artery; Gang | 2012 |
cAMP/protein kinase A activates cystic fibrosis transmembrane conductance regulator for ATP release from rat skeletal muscle during low pH or contractions.
Topics: 1-Methyl-3-isobutylxanthine; Adenosine Triphosphate; Animals; Benzoates; Cell Line; Colforsin; Cycli | 2012 |
Involvement of the NO-cGMP-K(ATP) channel pathway in the mesenteric lymphatic pump dysfunction observed in the guinea pig model of TNBS-induced ileitis.
Topics: Animals; ATP-Binding Cassette Transporters; Disease Models, Animal; Enzyme Inhibitors; Glyburide; Gu | 2013 |
Inhibition of human and pig ureter motility in vitro and in vivo by the K(+) channel openers PKF 217-744b and nicorandil.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Calcium Channels; Dose-Response Relationship, Drug; F | 2002 |
New approach to treatment of shock--restitution of vasoreactivity.
Topics: Animals; Blood Pressure; Dimethyl Sulfoxide; Disease Models, Animal; Dopamine; Glyburide; Hemodynami | 2002 |
Modulation of slow waves by hyperpolarization with potassium channel openers in antral smooth muscle of the guinea-pig stomach.
Topics: Adrenergic alpha-Agonists; Animals; ATP-Binding Cassette Transporters; Biological Clocks; Decanoic A | 2003 |
5-HT decreases contractile and electrical activities in lymphatic vessels of the guinea-pig mesentery: role of 5-HT 7-receptors.
Topics: Animals; Female; Glyburide; Guinea Pigs; In Vitro Techniques; Isoquinolines; Lymphatic Vessels; Male | 2003 |
Role of K(+) channels in the coronary and renal vascular reactivity to vasopressin in diabetic rats.
Topics: Animals; Blood Glucose; Charybdotoxin; Coronary Vessels; Diabetes Mellitus, Experimental; Dose-Respo | 2003 |
Mechanisms of vasorelaxation to 17beta-oestradiol in rat arteries.
Topics: Animals; Aorta, Thoracic; Calcium; Charybdotoxin; Cyclooxygenase Inhibitors; Endothelium, Vascular; | 2003 |
Contractile responses of isolated rat mesenteric arteries to acute episodes of severe hypoxia and subsequent reoxygenation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Adenosine Triph | 2004 |
KATP-channel-induced vasodilation is modulated by the Na,K-pump activity in rabbit coronary small arteries.
Topics: Animals; Arteries; ATP-Binding Cassette Transporters; Cardiotonic Agents; Coronary Vessels; Cromakal | 2004 |
Alteration of cyclopiazonic acid-mediated contracture of mouse diaphragm after denervation.
Topics: Action Potentials; Animals; Biological Assay; Boron Compounds; Caffeine; Cromakalim; Crotalid Venoms | 2005 |
K(+)-induced vasodilation in the rat kidney is dependent on the endothelium and activation of K+ channels.
Topics: Animals; Barium Compounds; Bradykinin; Carbenoxolone; Chlorides; Clotrimazole; Cytochrome P-450 Enzy | 2005 |
Acute systemic hypoxia elevates venous but not interstitial potassium of dog skeletal muscle.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Carbon Dioxide; Dogs; Female; Glyburide; Hydrogen-Io | 2005 |
Metamizol acts as an ATP sensitive potassium channel opener to inhibit the contracting response induced by angiotensin II but not to norepinephrine in rat thoracic aorta smooth muscle.
Topics: Adenosine Triphosphate; Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Tho | 2005 |
Antispasmodic and blood pressure lowering effects of Valeriana wallichii are mediated through K+ channel activation.
Topics: Animals; Cromakalim; Glyburide; Guinea Pigs; Hypoglycemic Agents; Ileum; In Vitro Techniques; Jejunu | 2005 |
[Effects of resveratrol on isolated thoracic aorta rings of rats].
Topics: Animals; Aorta, Thoracic; Calcium; Dose-Response Relationship, Drug; Drugs, Chinese Herbal; Endothel | 2005 |
Relative contribution of intracellular and extracellular Ca2+ to alpha2-adrenoceptor-mediated contractions of ovine pulmonary artery.
Topics: Adrenergic alpha-Agonists; Animals; Calcium; Calcium Channel Blockers; Cyclic AMP; Cyclic GMP; Glybu | 2006 |
Antispasmodic effects of Rooibos tea (Aspalathus linearis) is mediated predominantly through K+ -channel activation.
Topics: Animals; Apigenin; Aspalathus; Beverages; Diarrhea; Disease Models, Animal; Dose-Response Relationsh | 2006 |
Selective bronchodilatory effect of Rooibos tea (Aspalathus linearis) and its flavonoid, chrysoeriol.
Topics: Animals; Antihypertensive Agents; Aorta; Aspalathus; Bronchodilator Agents; Disease Models, Animal; | 2006 |
Direct inhibition of endothelial nitric oxide synthase by hydrogen sulfide: contribution to dual modulation of vascular tension.
Topics: Acetylcholine; Air Pollutants; Animals; Aorta; Enzyme Inhibitors; Glyburide; Guanylate Cyclase; Hydr | 2007 |
[Vasodilation effect of EUL on rat thoracic artery].
Topics: Animals; Aorta, Thoracic; Dose-Response Relationship, Drug; Endothelium, Vascular; Eucommiaceae; Fem | 2006 |
Effect of KATP channel openers on myogenic and neurogenic responses in goat urinary bladder.
Topics: Acetylcholine; Animals; Atropine; Cholinergic Agents; Cromakalim; Dose-Response Relationship, Drug; | 2007 |
Effects of extracellular HCO3(-) on fatigue, pHi, and K+ efflux in rat skeletal muscles.
Topics: Animals; Bicarbonates; Dose-Response Relationship, Drug; Female; Glyburide; Hydrogen-Ion Concentrati | 2007 |
KATP channel deficiency in mouse flexor digitorum brevis causes fibre damage and impairs Ca2+ release and force development during fatigue in vitro.
Topics: Adenosine Triphosphate; Animals; Calcium; Electric Stimulation; Glyburide; In Vitro Techniques; Mice | 2007 |
Na+-K+ pumps in the transverse tubular system of skeletal muscle fibers preferentially use ATP from glycolysis.
Topics: Adenosine Triphosphate; Animals; Chlorides; Energy Metabolism; Glyburide; Glycolysis; Hypoglycemic A | 2007 |
The effect of potassium channel opener pinacidil on the non-pregnant rat uterus.
Topics: Animals; Electric Stimulation; Female; Glyburide; In Vitro Techniques; Muscle Contraction; Oxytocics | 2007 |
Dual modulation of the tension of isolated gastric artery and gastric mucosal circulation by hydrogen sulfide in rats.
Topics: Animals; Arteries; Biological Factors; Blood Pressure; Endothelium, Vascular; Gastric Mucosa; Glybur | 2007 |
Evidence that BKCa channel activation contributes to K+ channel opener induced relaxation of the porcine coronary artery.
Topics: Animals; Benzopyrans; Calcium; Charybdotoxin; Coronary Vessels; Electrophysiology; Glyburide; Guanid | 1995 |
The effects of K+ channel blockers on the spontaneous electrical and contractile activity in the proximal renal pelvis of the guinea pig.
Topics: 4-Aminopyridine; Action Potentials; Animals; Apamin; Charybdotoxin; Female; Glyburide; Guinea Pigs; | 1996 |
Functional role of charybdotoxin-sensitive K+ channels in the resting state of cerebral, coronary and mesenteric arteries of the dog.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1993 |
Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Binding Sites; Drug Tolerance; Glyburide; Heart | 1993 |
Potassium channel inhibitors attenuate neuromodulatory effects of atrial natriuretic factor in the rabbit isolated vas deferens.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Animals; Atrial Natriuretic Factor; Benzopyrans; Charybdoto | 1994 |
Effects of K+ channel openers on the vascular actions of human gamma globulin.
Topics: Animals; Diazoxide; gamma-Globulins; Glyburide; Guanidines; Humans; In Vitro Techniques; Male; Muscl | 1994 |
Contribution of potassium channels to active hyperemia of the canine diaphragm.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Apamin; Blood Gas Analysis; Diaphragm; Dogs; Electric Stimulat | 1994 |
Vasodilating actions of cromakalim in resting and contracting states of carotid arteries from spontaneously hypertensive rats.
Topics: Animals; Benzopyrans; Carotid Arteries; Charybdotoxin; Cromakalim; Drug Interactions; Glyburide; In | 1994 |
Functional evidence for a glibenclamide-sensitive K+ channel in rat ileal smooth muscle.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1994 |
Propagation of impulses in the guinea-pig ureter and its blockade by calcitonin gene-related peptide (CGRP).
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1995 |
Contribution of activation of K+ channels to glyceryl trinitrate-induced relaxation of rabbit aorta.
Topics: 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Aorta, Thoracic; Apamin; Charybdotoxin; Cyclic GMP; En | 1995 |
The effects of glibenclamide on tetanic force and intracellular calcium in normal and fatigued mouse skeletal muscle.
Topics: Acidosis; Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Electric Stimulation; G | 1995 |
Effect of Kil769, a novel K(+)-channel opener, on sensitivity to Ca2+ of contractile elements and inositol phosphate formation in porcine coronary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Calcium; Calcium Channe | 1995 |
K-channel opening activity of dihydropyridine ZM244085: effect on 86Rb efflux and 3H-P1075 binding in urinary bladder smooth muscle.
Topics: Acridines; Animals; Glyburide; Guanidines; Guinea Pigs; Humans; In Vitro Techniques; Isradipine; Mus | 1995 |
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.
Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoprote | 1993 |
Ion channel involvement in the acute vascular effects of thiazide diuretics and related compounds.
Topics: Animals; Calcium Channels; Charybdotoxin; Diuretics; Drug Interactions; Glyburide; Guinea Pigs; Hydr | 1993 |
Cromakalim inhibits multiple mechanisms of smooth muscle activation with similar stereoselectivity.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Calcium; Cromakalim; Glyburide; In Vitro Techniques; Muscle C | 1993 |
A simple method for measurement of ureteric peristaltic function in vivo and the effects of drugs acting on ion channels applied from the ureter lumen in anesthetized rats.
Topics: 4-Aminopyridine; Anesthesia; Animals; Benzopyrans; Cromakalim; Glyburide; Ion Channels; Lidocaine; M | 1993 |
Cardioprotective profile of the cardiac-selective ATP-sensitive potassium channel opener BMS-180448.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Aorta; Benzopyrans; Cromakalim; Decanoic Ac | 1995 |
Activation by intracellular GDP, metabolic inhibition and pinacidil of a glibenclamide-sensitive K-channel in smooth muscle cells of rat mesenteric artery.
Topics: Animals; Deoxyglucose; Electrophysiology; Glyburide; Guanidines; Guanosine Diphosphate; Male; Mesent | 1995 |
The effects of potassium channel openers and blockers on the specific binding sites for [3H]glibenclamide in rat tissues.
Topics: Animals; Binding Sites; Brain; Cell Membrane; Dose-Response Relationship, Drug; Glyburide; Heart Ven | 1995 |
Endothelium-dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Atropine; Biological Factor | 1995 |
Effects of potassium channel activators on isolated cerebral arteries of large and small diameter in the cat.
Topics: Animals; Benzopyrans; Cats; Cerebral Arteries; Cromakalim; Dihydropyridines; Dose-Response Relations | 1995 |
Endogenous adenosine mediates coronary vasodilation during exercise after K(ATP)+ channel blockade.
Topics: Adenosine; Animals; Coronary Circulation; Diastole; Dogs; Glyburide; Guanidines; Hemodynamics; Hyper | 1995 |
Calcitonin gene-related peptide relaxes cholecystokinin-induced tension in Iguana iguana gallbladder strips.
Topics: Animals; Arginine; Calcitonin Gene-Related Peptide; Cholecystokinin; Gallbladder; Glyburide; Iguanas | 1994 |
Inhibitory transmitter action of calcitonin gene-related peptide in guinea-pig ureter via activation of glibenclamide-sensitive K channels.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Electric Stimulation; Electrophysiology; Glybur | 1994 |
Smooth muscle hyperpolarization and relaxation to acetylcholine in the rabbit basilar artery.
Topics: Acetylcholine; Animals; Basilar Artery; Female; Glyburide; In Vitro Techniques; Male; Membrane Poten | 1994 |
Multiple mechanisms in the smooth muscle relaxant action of calcitonin gene-related peptide (CGRP) in the guinea-pig ureter.
Topics: Action Potentials; Animals; Arginine; Benzopyrans; Calcitonin Gene-Related Peptide; Colforsin; Croma | 1994 |
Effects of diazoxide on norepinephrine-induced vasocontraction and ischemic myocardium in rats.
Topics: Analysis of Variance; Animals; Aorta, Thoracic; Calcium; Diazoxide; Disease Models, Animal; Dose-Res | 1994 |
An ATP-sensitive potassium channel blocker decreases diaphragmatic circulation in anesthetized dogs.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Carbon Dioxide; Diaphragm; Dogs; Glyburide; Muscle Cont | 1994 |
Mechanisms of vasorelaxation induced by N-allylsecoboldine in rat thoracic aorta.
Topics: Adrenergic alpha-1 Receptor Antagonists; Animals; Aorta, Thoracic; Aporphines; Benzopyrans; Calcium | 1994 |
The effect of glibenclamide on frog skeletal muscle: evidence for K+ATP channel activation during fatigue.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Glyburide; Membrane Potentials; Muscle Contracti | 1994 |
Effects of hydrochlorothiazide on contraction and 86Rb efflux in rat aorta.
Topics: Animals; Aorta, Thoracic; Barium Compounds; Chlorides; Glyburide; Hydrochlorothiazide; In Vitro Tech | 1993 |
Effect of cromakalim and glibenclamide on spontaneous and evoked motility of the guinea-pig isolated renal pelvis and ureter.
Topics: Action Potentials; Animals; Benzopyrans; Cromakalim; Electrophysiology; Glyburide; Guinea Pigs; In V | 1994 |
The effects of racemic cromakalim, BRL 38226 and levcromakalim on the membrane potential of the rat aorta and of BRL 38226 on the contractile activity of the rat aorta and portal vein.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Isoproterenol; Me | 1994 |
Effects of epithelial cell supernatant on membrane potential and contraction of dog airway smooth muscles.
Topics: Animals; Arginine; Bronchi; Cells, Cultured; Dogs; Electrophysiology; Epithelial Cells; Epithelium; | 1994 |
Effects of K-channel openers on the contractility and electrical activity of antral circular muscle in guinea-pig stomach.
Topics: Action Potentials; Animals; Benzopyrans; Cromakalim; Glyburide; Guinea Pigs; In Vitro Techniques; Io | 1993 |
Tolbutamide, but not glyburide, affects the excitability and contractility of unfatigued frog sartorius muscle.
Topics: Action Potentials; Animals; Electric Stimulation; Glyburide; Hydrogen-Ion Concentration; Muscle Cont | 1993 |
ATP-sensitive potassium channels and skeletal muscle function in vitro.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; Energy Metabolism; Gallamine Triethiodide; G | 1993 |
O2 occlusion and cyanide induced immediate relaxation and contraction of murine skeletal muscle.
Topics: Animals; Caffeine; Cyanides; Electric Stimulation; Glyburide; Hypoxia; In Vitro Techniques; Mice; Mi | 1993 |
Effects of KC 399, a novel ATP-sensitive K+ channel opener, on electrical and mechanical responses in dog tracheal smooth muscle.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Carbachol; Cromakalim; Cyclic AMP; Cyclic GMP; Dogs; F | 1994 |
Effects of cromakalim on the electrical slow wave in the circular muscle of guinea-pig gastric antrum.
Topics: Animals; Benzopyrans; Cromakalim; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro Techni | 1993 |
Involvement of ATP-sensitive K+ channels in the sustained coronary vasodilator response to adenosine in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Female; Gl | 1993 |
Effect of cromakalim on KCl-, noradrenaline- and angiotensin II-induced contractions in the rat pulmonary artery.
Topics: Angiotensin II; Animals; Benzopyrans; Bronchodilator Agents; Cromakalim; Glyburide; In Vitro Techniq | 1993 |
Inhibitory effect of cromakalim in human detrusor muscle is mediated by glibenclamide-sensitive potassium channels.
Topics: Benzopyrans; Cromakalim; Depression, Chemical; Dose-Response Relationship, Drug; Glyburide; Humans; | 1993 |
Activation of ATP-dependent K+ channels enhances myocardial protection due to cold high potassium cardioplegia: a force-frequency relationship study.
Topics: Animals; Cold Temperature; Glyburide; Guinea Pigs; Heart; Heart Arrest, Induced; Ion Channel Gating; | 1995 |
Ionic currents and inhibitory effects of glibenclamide in seminal vesicle smooth muscle cells.
Topics: 4-Aminopyridine; Amifampridine; Animals; Barium; Biological Transport, Active; Cadmium; Calcium; Cal | 1995 |
Coexistence of two classes of glibenclamide-inhibitable ATP-regulated K+ channels in avian skeletal muscle.
Topics: Adenosine Triphosphate; Animals; Cell Differentiation; Cells, Cultured; Chick Embryo; Electrophysiol | 1995 |
Effects of potassium channel modulators cromakalim, tetraethylammonium and glibenclamide on the contractility of the isolated human ureter.
Topics: Benzopyrans; Cromakalim; Glyburide; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; | 1996 |
Comparative effects of K+ channel modulating agents on contractions of rat intestinal smooth muscle.
Topics: Animals; Electric Stimulation; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Potassium C | 1996 |
Effect of exercise and 2-deoxyglucose on the K+ channel opener action of CGRP in the guinea pig ureter.
Topics: Animals; Antimetabolites; Calcitonin Gene-Related Peptide; Deoxyglucose; Glyburide; Guinea Pigs; Hyp | 1996 |
The effects of pharmacological modulation of KATP on the guinea-pig isolated diaphragm.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Diaphragm; Electrophysiology; Glyburide; G | 1996 |
Role of intracellular Ca2+ in the K channel opener action of CGRP in the guinea-pig ureter.
Topics: Animals; Caffeine; Calcitonin Gene-Related Peptide; Calcium; Calcium-Transporting ATPases; Electric | 1996 |
Smooth muscle relaxant activity of A1- and A2-selective adenosine receptor agonists in guinea pig trachea: involvement of potassium channels.
Topics: Adenosine; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Glyburide; Guinea Pi | 1996 |
Pharmacodynamic behaviour of isolated resistance vessels obtained from hypertensive-diabetic rats.
Topics: Animals; Benzopyrans; Blood Glucose; Calcium Channels; Calcium Chloride; Cromakalim; Glyburide; Hype | 1996 |
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Croma | 1996 |
Postjunctional effect of pinacidil on contractility of isolated bovine trachealis.
Topics: Acetylcholine; Animals; Cattle; Cell Membrane; Dose-Response Relationship, Drug; Electric Stimulatio | 1996 |
Actions of galanin and some of its analogues on rat isolated gastric fundus.
Topics: Analysis of Variance; Animals; Bucladesine; Calcium Channel Blockers; Dibenzylchlorethamine; Diltiaz | 1996 |
Mechanism of hydroxyl radical-induced modulation of vascular tone.
Topics: Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Glyburide; Hydroxyl Radical; Indomethacin; | 1997 |
Relaxant effect of levcromakalim in isolated human small subcutaneous arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Adolesce | 1995 |
In swine myocardium, the infarct size reduction induced by U-89232 is glibenclamide sensitive: evidence that U-89232 is a cardioselective opener of ATP-sensitive potassium channels.
Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Vessels; Glyburide; Guanidines; Heart; Muscle C | 1997 |
Apamin blocks the direct relaxant effect of melatonin on rat ileal smooth muscle.
Topics: 4-Aminopyridine; Adrenergic alpha-Antagonists; Animals; Apamin; Calcium; Calcium Channel Blockers; C | 1997 |
Potent inhibition by tamoxifen of spontaneous and agonist-induced contractions of the human myometrium and intramyometrial arteries.
Topics: Arteries; Clomiphene; Cyclofenil; Estrogen Antagonists; Female; Glyburide; Humans; Muscle Contractio | 1997 |
Effects of BKCa channels on the reduction of cytosolic Ca2+ in cGMP-induced relaxation of guinea-pig trachea.
Topics: Animals; Apamin; Atrial Natriuretic Factor; Calcium; Cyclic GMP; Cytosol; Extracellular Space; Glybu | 1997 |
NS 1619 activates Ca2+-activated K+ currents in rat vas deferens.
Topics: Adrenergic alpha-Agonists; Animals; Benzimidazoles; Calcium; Charybdotoxin; Electric Stimulation; Ep | 1997 |
Heterogeneity of the inhibitory influence of sulfonylureas on prostanoid-induced smooth muscle contraction.
Topics: Animals; Aorta, Thoracic; Arteries; Bronchi; Cattle; Drug Interactions; Female; Gliclazide; Glyburid | 1997 |
Effects of putative K+ channel blockers on beta-adrenoceptor-mediated vasorelaxation of rat mesenteric artery.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Barium; Benzopyrans; Calcium; Charybdotox | 1997 |
Involvement of ATP-sensitive K+ channels in the inhibitory effect of calcitonin gene-related peptide on neurotransmission in rat vas deferens.
Topics: Adenosine Triphosphate; Animals; Calcitonin Gene-Related Peptide; Glyburide; Humans; Male; Muscle Co | 1997 |
Role of Ca(2+)-activated K+ channel in epithelium-dependent relaxation of human bronchial smooth muscle.
Topics: Acetylcholine; Apamin; Bronchi; Calcium; Glyburide; Humans; Hypoglycemic Agents; Muscle Contraction; | 1997 |
Blocking ATP-sensitive K+ channel during metabolic inhibition impairs muscle contractility.
Topics: Action Potentials; Animals; Glyburide; In Vitro Techniques; Iodoacetates; Iodoacetic Acid; Kinetics; | 1997 |
Capacitative Ca2+ entry associated with alpha1-adrenoceptors in rat aorta.
Topics: Animals; Aorta; Benzopyrans; Calcium; Calcium Channel Blockers; Calcium Channels; Cromakalim; Glybur | 1997 |
Heterogeneity in the vasorelaxing effect of nicorandil on dog epicardial coronary arteries: comparison with other NO donors.
Topics: Animals; Atrial Natriuretic Factor; Benzopyrans; Coronary Vessels; Cromakalim; Cyclic GMP; Dogs; Fem | 1997 |
Possible involvement of ATP-dependent K-channel related mechanisms in the antihypertensive and cough suppressant effects of the novel ACE inhibitor (2S, 3aS, 7aS)-1-(N2-nicotinoyl-L-lysyl-gamma-D-glutamyl)octahydro-1H- indole-2-carboxylic acid.
Topics: Adenosine Triphosphate; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; | 1997 |
The comparison of the responsiveness of human isolated internal mammary and gastroepiploic arteries to levcromakalim: an alternative approach to the management of graft spasm.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Arteries; Benzopyrans; Coronary | 1997 |
Interactions between neuropeptide Y and the adenylate cyclase pathway in rat mesenteric small arteries: role of membrane potential.
Topics: 4-Aminopyridine; Acetylcholine; Adenylyl Cyclases; Animals; Charybdotoxin; Colforsin; Cyclic AMP-Dep | 1997 |
Evidence for alpha 2-adrenoceptor agonist activity of minoxidil.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Diethylstilbestrol; Female; Glybur | 1997 |
Disparate effects of antidiabetic drugs on arterial contraction.
Topics: Animals; Arteries; Blood Pressure; Glyburide; Humans; Hypoglycemic Agents; In Vitro Techniques; Insu | 1997 |
Ca2+-entry blockade by CAF603, a carotane sesquiterpene isolated from Trichoderma virens.
Topics: Animals; Calcium Channel Blockers; Glyburide; Guinea Pigs; In Vitro Techniques; Intestine, Small; Mu | 1997 |
Glibenclamide inhibits thromboxane A2-induced contraction in human internal mammary artery and saphenous vein.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Biphenyl Compounds; Dose-Respons | 1998 |
Stretch-evoked inhibition of spontaneous migrating contractions in a whole mount preparation of the guinea-pig upper urinary tract.
Topics: Animals; Calcitonin Gene-Related Peptide; Capsaicin; Female; Glyburide; Guinea Pigs; In Vitro Techni | 1998 |
Differential sensitivity to ATP-sensitive potassium channel openers of norepinephrine-induced contraction of guinea pig and rat aorta.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Cromakalim; Diltiazem; Dose-Response Relationship, | 1998 |
Involvement of intracellular Ca2+ stores in inhibitory effects of NO donor SIN-1 and cGMP.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1998 |
ATP-sensitive K+ channel blocker glibenclamide and diaphragm fatigue during normoxia and hypoxia.
Topics: Adenosine Triphosphate; Animals; Diaphragm; Electric Stimulation; Glyburide; Hypoglycemic Agents; Hy | 1998 |
Levcromakalim decreases vascular tone, cytoplasmic Ca2+ and Ca2+ sensitivity in canine basilar artery.
Topics: Animals; Basilar Artery; Calcium; Calcium Channel Blockers; Cromakalim; Cytoplasm; Dogs; Dose-Respon | 1998 |
Effect of diazoxide, an ATP-dependent potassium-channel opener, on isolated aortae of normal and diabetic rats.
Topics: Animals; Antihypertensive Agents; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diazoxide; Glybu | 1998 |
ATP-sensitive K+ current and its modulation by substance P in gastric myocytes isolated from guinea pig.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Barium; Cesium; Cromakalim; Female; Glyburide; G | 1998 |
Effect of age on the vasorelaxation elicited by cromakalim. Role of K+ channels and cyclic GMP.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Aging; Animals; Aorta, Thoracic; Cromakalim; Cyclic GMP; End | 1998 |
Involvement of K+ATP channels in nitric oxide-induced inhibition of spontaneous contractile activity of the nonpregnant human myometrium.
Topics: Adult; Female; Glyburide; Guanylate Cyclase; Humans; Methylene Blue; Middle Aged; Muscle Contraction | 1998 |
Differential effects of pinacidil, cromakalim, and NS 1619 on electrically evoked contractions in rat vas deferens.
Topics: Animals; Benzimidazoles; Charybdotoxin; Cromakalim; Electric Stimulation; Glyburide; In Vitro Techni | 1997 |
Possible involvement of K+ channel opening to the interleukin-1 beta-induced inhibition of vascular smooth muscle contraction.
Topics: Animals; Aorta; Calcium; Glyburide; Hypoglycemic Agents; Interleukin-1; Ion Channel Gating; Male; Mu | 1999 |
Effects of K(+)-channel blockers on A1-adenosine receptor-mediated negative inotropy and chronotropy of guinea-pig isolated left and right atria.
Topics: 4-Aminopyridine; Adenosine; Animals; Dose-Response Relationship, Drug; Drug Interactions; Glyburide; | 1999 |
Effects of ZD6169, a K(ATP) channel opener, on the micturition reflex in the rat.
Topics: Adenosine Triphosphate; Amides; Animals; Benzophenones; Capsaicin; Female; Glyburide; Hypoglycemic A | 1999 |
Protection of human myocardium in vitro by K(ATP) activation with low concentrations of bimakalim.
Topics: Adenosine Triphosphate; Adult; Benzopyrans; Dihydropyridines; Dobutamine; Dose-Response Relationship | 1999 |
Involvement of ATP-sensitive potassium channels in a model of a delayed vascular hyporeactivity induced by lipopolysaccharide in rats.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Blood Pressure; Cromakalim; Enzyme Inhibitors; Gly | 1999 |
Cardioselective antiischemic ATP-sensitive potassium channel (K(ATP)) openers. 6. Effect of modifications at C6 of benzopyranyl cyanoguanidines.
Topics: Animals; Benzopyrans; Cardiotonic Agents; Glyburide; Guanidines; Heart; Muscle Contraction; Myocardi | 1999 |
Pharmacological characterization of metamizol-induced relaxation in phenylephrine-precontracted rabbit thoracic aorta smooth muscle.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Aorta, Thoracic; Dipyrone; Dose-Response Relations | 1999 |
Threshold concentrations of endothelin-1: the effects on contractions induced by 5-hydroxytryptamine in isolated rat cerebral and mesenteric arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Basilar Artery; Bipheny | 1999 |
The myoneural effects of lithium chloride on the nerve-muscle preparations of rats. Role of adenosine triphosphate-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Antimanic Agents; ATP-Binding Cassette Transporters; Calcium Channe | 2000 |
Pinacidil suppresses contractility and preserves energy but glibenclamide has no effect during muscle fatigue.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Energy Metabolism; Glyburide; Hypoglycemic Agent | 2000 |
K(ATP) channels mediate the beta(2)-adrenoceptor agonist-induced relaxation of rat detrusor muscle.
Topics: Adenosine Triphosphate; Adrenergic beta-Agonists; Animals; Clenbuterol; Colforsin; Cyclic AMP; Cycli | 2000 |
Pharmacological and molecular analysis of ATP-sensitive K(+) channels in the pig and human detrusor.
Topics: Adenosine Triphosphate; Animals; Carbachol; Electric Stimulation; Female; Glyburide; Humans; Muscle | 2000 |
The effects of potassium channel blockers on progesterone-induced suppression of rat portal vein contractility.
Topics: 4-Aminopyridine; Animals; Barium Compounds; Chlorides; Glyburide; Hypoglycemic Agents; Male; Muscle | 2000 |
Clonidine attenuates the carbachol-induced contractile and phosphatidylinositol responses of rat trachea.
Topics: Aluminum Compounds; Analgesics; Animals; Carbachol; Clonidine; Dose-Response Relationship, Drug; Flu | 2000 |
Low levels of K(ATP) channel activation decrease excitability and contractility of urinary bladder.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Amides; Animals; Benzophenones; Cr | 2001 |
Denervation enhances the physiological effects of the K(ATP) channel during fatigue in EDL and soleus muscle.
Topics: Adenosine Triphosphate; Animals; Female; Gene Expression; Glyburide; Hypoglycemic Agents; Mice; Mice | 2001 |
Original 2-alkylamino-6-halogenoquinazolin-4(3H)-ones and K(ATP) channel activity.
Topics: Adenosine Triphosphate; Animals; Aorta; Calcium; Crystallography, X-Ray; Female; Glyburide; Guinea P | 2001 |
Dual mechanism of action of nicorandil on rabbit corpus cavernosal smooth muscle tone.
Topics: Adenosine Triphosphate; Adrenergic alpha-Agonists; Animals; Enzyme Activation; Enzyme Inhibitors; Gl | 2001 |
Effect of acidosis on contractile function of mesenterial lymphatic vessels in bulls.
Topics: Acidosis; Animals; Anti-Arrhythmia Agents; Barium Compounds; Cattle; Chlorides; Glyburide; Hydrogen- | 2001 |
Relaxation and modulation of cyclic AMP production in response to atrial natriuretic peptides in guinea pig tracheal smooth muscle.
Topics: Adenylyl Cyclases; Animals; Apamin; Atrial Natriuretic Factor; Colforsin; Cyclic AMP; Dose-Response | 2001 |
Effects of different types of K+ channel modulators on the spontaneous myogenic contraction of guinea-pig urinary bladder smooth muscle.
Topics: 4-Aminopyridine; Animals; Anti-Arrhythmia Agents; Apamin; Barium; Benzimidazoles; Calcium Channel Bl | 2001 |
The role of K(+) channels on the inhibitor effect of sevoflurane in pregnant rat myometrium.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Dose-Response Relationship, Drug; Female; | 2002 |
Multiple dilator pathways in skeletal muscle contraction-induced arteriolar dilations.
Topics: Adenosine; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arterioles; Cricetinae; Enzyme I | 2002 |
Mouse model of Prinzmetal angina by disruption of the inward rectifier Kir6.1.
Topics: Angina Pectoris, Variant; Animals; Aorta, Thoracic; Blood Pressure; Coronary Vessels; Disease Models | 2002 |
Myocardial preconditioning factors evoke mesenteric ischemic tolerance via opioid receptors and K(ATP) channels.
Topics: Animals; Chromatography, High Pressure Liquid; Glyburide; In Vitro Techniques; Ischemia; Ischemic Pr | 2002 |
The pharmacology of a new hypoglycaemic agent N-[4-(2-(2,3-dihydrobenzo(b)furan-7-carboxamid o)-ethyl)-benzenesulphonyl]-N'-cyclohexlurea (NOVO CS 476). III. General pharmacological studies.
Topics: Animals; Blood Pressure; Cats; Chlorpropamide; Diuresis; Dogs; Female; Glyburide; Guinea Pigs; Heart | 1977 |
Calcitonin gene related peptide relaxes cholecystokinin-induced contraction in guinea pig gallbladder strips in vitro.
Topics: Animals; Arginine; Atropine; Calcitonin Gene-Related Peptide; Cholecystokinin; Gallbladder; Glyburid | 1992 |
Vasodilatation of canine cerebral arteries by nicorandil, pinacidil and lemakalim.
Topics: Animals; Basilar Artery; Benzopyrans; Cerebral Arteries; Cromakalim; Dogs; Female; Glyburide; Guanid | 1992 |
Effects of cromakalim on the contraction and the membrane potential of the circular smooth muscle of guinea-pig stomach.
Topics: Acetylcholine; Animals; Benzopyrans; Charybdotoxin; Cromakalim; Electric Stimulation; Glyburide; Gui | 1992 |
Vasorelaxing effect in rat thoracic aorta caused by fraxinellone and dictamine isolated from the Chinese herb Dictamnus dasycarpus Turcz: comparison with cromakalim and Ca2+ channel blockers.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1992 |
Mechanisms of action of cicletanine in human and guinea pig resistance arteries.
Topics: Animals; Antihypertensive Agents; Arteries; Charybdotoxin; Diuretics; Drug Interactions; Eicosanoids | 1992 |
Ca2+ release from isolated sarcoplasmic reticulum of guinea-pig psoas muscle induced by K(+)-channel blockers.
Topics: 4-Aminopyridine; Animals; Apamin; Calcium; Charybdotoxin; Glyburide; Guinea Pigs; In Vitro Technique | 1992 |
On the pharmacological and physiological role of glibenclamide-sensitive potassium channels in colonic smooth muscle.
Topics: Animals; Benzopyrans; Carbachol; Colforsin; Colon; Cromakalim; Dogs; Drug Interactions; Electric Sti | 1992 |
The involvement of potassium channels in the action of ciclazindol in rat portal vein.
Topics: Animals; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Indoles; Male; Membrane Potentials | 1992 |
Comparison of the actions of acetylcholine and BRL 38227 in the guinea-pig coronary artery.
Topics: Acetylcholine; Animals; Benzopyrans; Coronary Vessels; Cromakalim; Dose-Response Relationship, Drug; | 1992 |
Effects of LP-805, a novel vasorelaxant agent, a potassium channel opener, on rat thoracic aorta.
Topics: Animals; Aorta, Thoracic; Calcium; Cytosol; Fura-2; Glyburide; In Vitro Techniques; Male; Muscle Con | 1992 |
Effects on the rabbit coronary artery of LP-805, a new type of releaser of endothelium-derived relaxing factor and a K+ channel opener.
Topics: Acetylcholine; Action Potentials; Animals; Coronary Vessels; Glyburide; In Vitro Techniques; Indomet | 1992 |
Effect of a sulphonylurea on dog skeletal muscle performance during fatiguing work.
Topics: Animals; Dogs; Fatigue; Female; Glyburide; Male; Muscle Contraction; Potassium; Potassium Channels | 1992 |
Activation of ATP-sensitive K channels by a K channel opener (SR 44866) and the effect upon electrical and mechanical activity of frog skeletal muscle.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cell Membrane; Dihydropyridines; Do | 1991 |
Characterization of sulfonylurea receptors and the action of potassium channel openers on cholinergic neurotransmission in guinea pig isolated small intestine.
Topics: Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Benzopyrans; Choline; Cromakalim | 1991 |
Nicorandil: differential contribution of K+ channel opening and guanylate cyclase stimulation to its vasorelaxant effects on various endothelin-1-contracted arterial preparations. Comparison to aprikalim (RP 52891) and nitroglycerin.
Topics: Animals; Coronary Vessels; Endothelins; Endothelium, Vascular; Glyburide; Guanylate Cyclase; Heart; | 1991 |
Actions of cromakalim in isolated human saphenous vein.
Topics: Antihypertensive Agents; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Humans; In Vitro Techniques; | 1992 |
Inhibition by glibenclamide of the effects of cromakalim on responses of rat vas deferens to naphazoline.
Topics: Animals; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Male; Muscle Contraction; Muscle, | 1991 |
The effect of potassium channel opening drugs on pulmonary nerves.
Topics: Acetylcholine; Animals; Benzopyrans; Cromakalim; Electric Stimulation; Glyburide; Guinea Pigs; In Vi | 1991 |
An analysis of the nitrate-like and K channel opening actions of KRN2391 in canine coronary arterial smooth muscle.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Antihypertensive Agents | 1991 |
NIP-121 and cromakalim, potassium channel openers, preferentially suppress prostanoid-induced contraction of the guinea-pig isolated trachea.
Topics: Animals; Arachidonic Acid; Benzopyrans; Cromakalim; Dinoprost; Glyburide; Guinea Pigs; Indomethacin; | 1991 |
The dualistic mode of action of the vasodilator drug, nicorandil, differentiated by glibenclamide in 86Rb flux studies in rabbit isolated vascular smooth muscle.
Topics: Animals; Aorta; Benzopyrans; Cromakalim; Glyburide; Membranes; Muscle Contraction; Muscle, Smooth, V | 1991 |
Differential antagonism by glibenclamide of the relaxant effects of cromakalim, pinacidil and nicorandil on canine large coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arteries; Benzopyrans; | 1991 |
Glibenclamid-sensitive K+ channels are responsible for angiotensin II hypersensitive contraction and atrial natriuretic factor refractoriness of glomeruli in low-sodium rats.
Topics: Angiotensin II; Animals; Atrial Natriuretic Factor; Capillaries; Diuretics; Glyburide; Inulin; Kidne | 1991 |
Effects of glibenclamide on cytosolic calcium concentrations and on contraction of the rabbit aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Calcium; Cromakalim; Cytosol; Fura-2; Glyburide; In Vitro Tec | 1991 |
Metabolic correlates to pacemaker activity in the smooth muscle of guinea-pig mesotubarium.
Topics: Adenosine Triphosphate; Animals; Biological Clocks; Biological Transport, Active; Felodipine; Female | 1991 |
Glibenclamide relaxes vascular smooth muscle constriction produced by prostaglandin F2 alpha.
Topics: Animals; Arteries; Dinoprost; Dogs; Endothelium, Vascular; Female; Glyburide; In Vitro Techniques; M | 1991 |
Evidence that acetylcholine-mediated hyperpolarization of the rat small mesenteric artery does not involve the K+ channel opened by cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Cromakalim; Electrophysiology; Glyburide; In Vitro Techniques; | 1991 |
Some degree of overlap exists between the K(+)-channels opened by cromakalim and those opened by minoxidil sulphate in rat isolated aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; In Vitro Techniques; Male; Minoxidil; | 1991 |
Evidence that pinacidil may promote the opening of ATP-sensitive K+ channels yet inhibit the opening of Ca2(+)-activated K+ channels in K(+)-contracted canine mesenteric artery.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Dogs; Female; Glyburide; Guanidin | 1990 |
Characterization of responses to cromakalim and pinacidil in smooth and cardiac muscle by use of selective antagonists.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Clonidine; Coronary Vessels; Cromakalim; Dogs; Electric Stimu | 1990 |
Hypoglycemic sulfonylureas antagonize the effects of cromakalim and pinacidil on 86Rb fluxes and contractile activity in the rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Glyburide; Guanidines; Hypoglycemic Agents; In Vi | 1990 |
Glibenclamide is a competitive antagonist of the thromboxane A2 receptor in dog coronary artery in vitro.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Coronary Vessels; Dogs; | 1990 |
Cytoplasmic calcium and the relaxation of canine coronary arterial smooth muscle produced by cromakalim, pinacidil and nicorandil.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Coronary Vessels; Cromakalim; Cytoplasm; Dogs | 1990 |
Mechanisms of inhibitory effects of CD-349 and K(+)-channel activators on noradrenaline-induced contraction and changes in levels of cyclic GMP in rat aorta.
Topics: Animals; Aorta, Thoracic; Benzopyrans; Calcium Channel Agonists; Calcium Channel Blockers; Cromakali | 1990 |
Effects of cromakalim and glibenclamide on isolated strips of bovine tracheal smooth muscle. Smooth Muscle Research Group.
Topics: Animals; Benzopyrans; Cattle; Cromakalim; Glyburide; In Vitro Techniques; Muscle Contraction; Muscle | 1989 |
Effect of cromakalim on smooth muscle cells of guinea-pig taenia caeci.
Topics: Animals; Benzopyrans; Cecum; Cromakalim; Electrophysiology; Female; Glyburide; Guinea Pigs; In Vitro | 1989 |
Glibenclamide is a competitive antagonist of cromakalim, pinacidil and RP 49356 in guinea-pig pulmonary artery.
Topics: Animals; Benzopyrans; Cromakalim; Glyburide; Guanidines; Guinea Pigs; In Vitro Techniques; Male; Met | 1989 |