glyburide has been researched along with Melanoma in 2 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glyburide is a safe, inexpensive, and efficacious alternative to dexamethasone for the treatment of cerebral metastasis-related vasogenic edema." | 1.39 | Inhibition of SUR1 decreases the vascular permeability of cerebral metastases. ( Muldoon, LL; Neuwelt, EA; Pishko, GL; Thompson, EM, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thompson, EM | 1 |
| Pishko, GL | 1 |
| Muldoon, LL | 1 |
| Neuwelt, EA | 1 |
| Suzuki, Y | 1 |
| Inoue, T | 1 |
| Murai, M | 1 |
| Suzuki-Karasaki, M | 1 |
| Ochiai, T | 1 |
| Ra, C | 1 |
2 other studies available for glyburide and Melanoma
| Article | Year |
|---|---|
Inhibition of SUR1 decreases the vascular permeability of cerebral metastases.
Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Capillary Permeability; Cell Line, Tumor; | 2013 |
Depolarization potentiates TRAIL-induced apoptosis in human melanoma cells: role for ATP-sensitive K+ channels and endoplasmic reticulum stress.
Topics: Adamantane; Antineoplastic Agents; Apoptosis; Caspase 12; Caspase 3; Caspase 7; Endoplasmic Reticulu | 2012 |