glyburide has been researched along with Liver Failure, Acute in 1 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Liver Failure, Acute: A form of rapid-onset LIVER FAILURE, also known as fulminant hepatic failure, caused by severe liver injury or massive loss of HEPATOCYTES. It is characterized by sudden development of liver dysfunction and JAUNDICE. Acute liver failure may progress to exhibit cerebral dysfunction even HEPATIC COMA depending on the etiology that includes hepatic ISCHEMIA, drug toxicity, malignant infiltration, and viral hepatitis such as post-transfusion HEPATITIS B and HEPATITIS C.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Astrocyte swelling (cytotoxic brain edema) is the major neurological complication of acute liver failure (ALF), a condition in which ammonia has been strongly implicated in its etiology." | 1.40 | Sulfonylurea receptor 1 contributes to the astrocyte swelling and brain edema in acute liver failure. ( Gonzalez, W; Jayakumar, AR; Norenberg, MD; Shamaladevi, N; Tong, XY; Valdes, V, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jayakumar, AR | 1 |
| Valdes, V | 1 |
| Tong, XY | 1 |
| Shamaladevi, N | 1 |
| Gonzalez, W | 1 |
| Norenberg, MD | 1 |
1 other study available for glyburide and Liver Failure, Acute
| Article | Year |
|---|---|
Sulfonylurea receptor 1 contributes to the astrocyte swelling and brain edema in acute liver failure.
Topics: Ammonia; Animals; Astrocytes; Brain Edema; Cell Size; Cells, Cultured; Glyburide; Hypoglycemic Agent | 2014 |