Page last updated: 2024-10-28

glyburide and Leishmaniasis, Cutaneous

glyburide has been researched along with Leishmaniasis, Cutaneous in 5 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Leishmaniasis, Cutaneous: An endemic disease that is characterized by the development of single or multiple localized lesions on exposed areas of skin that typically ulcerate. The disease has been divided into Old and New World forms. Old World leishmaniasis is separated into three distinct types according to epidemiology and clinical manifestations and is caused by species of the L. tropica and L. aethiopica complexes as well as by species of the L. major genus. New World leishmaniasis, also called American leishmaniasis, occurs in South and Central America and is caused by species of the L. mexicana or L. braziliensis complexes.

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Carvalho, AM1
Novais, FO1
Paixão, CS1
de Oliveira, CI1
Machado, PRL1
Carvalho, LP1
Scott, P1
Carvalho, EM1
Silva, N1
Camacho, N1
Figarella, K2
Ponte-Sucre, A3
Serrano-Martín, X1
Payares, G1
Mendoza-León, A3
García, N1
Moll, H1

Other Studies

5 other studies available for glyburide and Leishmaniasis, Cutaneous

ArticleYear
Glyburide, a NLRP3 Inhibitor, Decreases Inflammatory Response and Is a Candidate to Reduce Pathology in Leishmania braziliensis Infection.
    The Journal of investigative dermatology, 2020, Volume: 140, Issue:1

    Topics: Biopsy; Brazil; Cells, Cultured; Cytokines; Endemic Diseases; Glyburide; Humans; Hypoglycemic Agents

2020
Cell differentiation and infectivity of Leishmania mexicana are inhibited in a strain resistant to an ABC-transporter blocker.
    Parasitology, 2004, Volume: 128, Issue:Pt 6

    Topics: Animals; ATP-Binding Cassette Transporters; Blotting, Western; Cell Differentiation; Drug Resistance

2004
Glibenclamide, a blocker of K+(ATP) channels, shows antileishmanial activity in experimental murine cutaneous leishmaniasis.
    Antimicrobial agents and chemotherapy, 2006, Volume: 50, Issue:12

    Topics: Adenosine Triphosphate; Animals; Antiprotozoal Agents; Dose-Response Relationship, Drug; Drug Resist

2006
Changes in the infectivity, pyruvate kinase activity, acid phosphatase activity and P-glycoprotein expression in glibenclamide-resistant Leishmania mexicana.
    Parasitology research, 2000, Volume: 86, Issue:11

    Topics: Acid Phosphatase; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line; Cultu

2000
Experimental leishmaniasis: synergistic effect of ion channel blockers and interferon-gamma on the clearance of Leishmania major by macrophages.
    Parasitology research, 2001, Volume: 87, Issue:1

    Topics: Animals; Cells, Cultured; Drug Synergism; Glyburide; Interferon-gamma; Ion Channels; Leishmania majo

2001