glyburide has been researched along with Ischemia in 31 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the dynamics of the intracellular Ca2+ concentration ([Ca2+]i) during retinal ischemia in rats with streptozotocin (STZ)-induced diabetes and the effect of gliclazide, a sulfonylurea with a potent free-radical scavenging activity on ischemia-induced [Ca2+]i dynamics." | 7.73 | Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. ( Harata, N; Kinukawa, J; Shimura, M; Tamai, M, 2005) |
| "We studied changes in arteriolar and venular diameters and macromolecular leakage altered by ischemia/reperfusion (I/R) and topically applied histamine after I/R and how these changes were modulated by cromakalim (KATP-channel opener) and glibenclamide (KATP-channel blocker)." | 7.71 | Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion. ( Bouskela, E; Simões, C; Svensjö, E, 2002) |
| "We used adenosine A1 receptor agonist N6-1(phenyl-2R-isopropyl)-adenosine (PIA), A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), and ATP-sensitive K+ (KATP) channel blockers sodium 5-hydroxydecanoate (5-HD) and glibenclamide (Glib), as probes to investigate the role and mechanism of adenosine in ischemic preconditioning (IPC) of noncontractile skeletal muscle against infarction, using the pig latissimus dorsi muscle flap model." | 7.69 | Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction. ( Forrest, CR; He, W; Neligan, P; Pang, CY; Xu, H; Zhong, A, 1997) |
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 7.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| "In type 2 diabetic patients, the vasodilating response to forearm ischemia was the same whether patients were treated with diet treatment alone or with glibenclamide or glimepiride at blood glucose-lowering equipotent closes." | 5.09 | Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia. ( Brunelli, C; Cordera, R; Cordone, S; Olivotti, L; Rossettin, P; Schiavo, M; Spallarossa, P, 2001) |
| " In this study, we investigated whether TZDs affect onset, spectral characteristics, and mortality of ischemic ventricular fibrillation (VF) and whether such effects are recapitulated by a non-selective K(ATP) blocker (glyburide) or a mitochondrial K(ATP) blocker (5-hydroxydecanoate)." | 3.78 | Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs. ( Greyson, CR; Lu, L; Reiter, MJ; Sarraf, M; Schwartz, GG; Ye, S, 2012) |
| "The aim of this study was to assess the potential beneficial effects of gliclazide and other sulphonylureas on ischemia-induced retinal neovascularization." | 3.74 | Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization. ( Kimura, T; Kita, M; Suzuma, K; Takagi, H; Watanabe, D; Yoshimura, N, 2007) |
| "To investigate the dynamics of the intracellular Ca2+ concentration ([Ca2+]i) during retinal ischemia in rats with streptozotocin (STZ)-induced diabetes and the effect of gliclazide, a sulfonylurea with a potent free-radical scavenging activity on ischemia-induced [Ca2+]i dynamics." | 3.73 | Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. ( Harata, N; Kinukawa, J; Shimura, M; Tamai, M, 2005) |
| "We studied changes in arteriolar and venular diameters and macromolecular leakage altered by ischemia/reperfusion (I/R) and topically applied histamine after I/R and how these changes were modulated by cromakalim (KATP-channel opener) and glibenclamide (KATP-channel blocker)." | 3.71 | Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion. ( Bouskela, E; Simões, C; Svensjö, E, 2002) |
| "We used adenosine A1 receptor agonist N6-1(phenyl-2R-isopropyl)-adenosine (PIA), A1 receptor antagonist 8-cyclopentyl-1,3-dipropylxanthine (DPCPX), and ATP-sensitive K+ (KATP) channel blockers sodium 5-hydroxydecanoate (5-HD) and glibenclamide (Glib), as probes to investigate the role and mechanism of adenosine in ischemic preconditioning (IPC) of noncontractile skeletal muscle against infarction, using the pig latissimus dorsi muscle flap model." | 3.69 | Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction. ( Forrest, CR; He, W; Neligan, P; Pang, CY; Xu, H; Zhong, A, 1997) |
| "kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 3.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
| " After dosing glibenclamide induced a significant (P = 0." | 2.71 | Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients. ( Boes, U; Wascher, TC, 2005) |
| "There were fewer malignant arrhythmias with PerC during reperfusion (P = 0." | 1.34 | Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning. ( Cheung, M; Dzavik, V; Kharbanda, RK; Konstantinov, IE; Kristiansen, SB; Li, J; Redington, AN; Schmidt, MR; Shimizu, M; Smerup, M; Sorensen, K; White, PA, 2007) |
| "Intestinal ischemia and reperfusion injury is dependent on the recruitment and activation of neutrophils." | 1.34 | Effects of the treatment with glibenclamide, an ATP-sensitive potassium channel blocker, on intestinal ischemia and reperfusion injury. ( Amaral, FA; Cunha, FQ; Fagundes, CT; Pompermayer, K; Souza, DG; Teixeira, MM; Vieira, AT, 2007) |
| "The diazoxide-mediated increase in the forearm blood flow ratio (infused/control arm) was significantly less pronounced after glibenclamide than after acarbose (290 +/- 58% and 561 +/- 101% respectively; P<0." | 1.31 | Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes. ( Abbink, EJ; Lutterman, JA; Pickkers, P; Russel, FG; Smits, P; Tack, CJ; van Rosendaal, AJ, 2002) |
| "The mechanism underlying reactive hyperemia was investigated in the feline hindquarters vascular bed under natural- and constant-flow conditions." | 1.29 | Role of K+ATP channels and EDRF in reactive hyperemia in the hindquarters vascular bed of cats. ( Kadowitz, PJ; McMahon, TJ; Minkes, RK; Santiago, JA, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (6.45) | 18.7374 |
| 1990's | 10 (32.26) | 18.2507 |
| 2000's | 17 (54.84) | 29.6817 |
| 2010's | 2 (6.45) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarraf, M | 1 |
| Lu, L | 1 |
| Ye, S | 1 |
| Reiter, MJ | 1 |
| Greyson, CR | 1 |
| Schwartz, GG | 1 |
| Emami, H | 1 |
| Talab, SS | 1 |
| Nezami, BG | 2 |
| Elmi, A | 1 |
| Assa, S | 1 |
| Ostovaneh, MR | 1 |
| Dehpour, AR | 2 |
| Lascano, EC | 1 |
| Negroni, JA | 1 |
| del Valle, HF | 1 |
| Capecchi, PL | 1 |
| Guideri, F | 1 |
| Colafati, M | 1 |
| Acampa, M | 1 |
| Cuomo, A | 1 |
| Lazzerini, PE | 1 |
| Pasini, FL | 1 |
| Wascher, TC | 1 |
| Boes, U | 1 |
| Milovanova, T | 1 |
| Chatterjee, S | 1 |
| Manevich, Y | 1 |
| Kotelnikova, I | 1 |
| Debolt, K | 1 |
| Madesh, M | 1 |
| Moore, JS | 1 |
| Fisher, AB | 1 |
| Kinukawa, J | 1 |
| Shimura, M | 1 |
| Harata, N | 1 |
| Tamai, M | 1 |
| Zager, RA | 1 |
| Johnson, AC | 1 |
| Lund, S | 1 |
| Hanson, SY | 1 |
| Abrass, CK | 1 |
| Beheshtian, A | 1 |
| Demehri, S | 1 |
| Kiumehr, S | 1 |
| Salmasi, AH | 1 |
| Ghazinezami, B | 1 |
| Rahimpour, S | 1 |
| Amanpour, S | 1 |
| Rabbani, S | 1 |
| Mohagheghi, MA | 1 |
| Schmidt, MR | 1 |
| Smerup, M | 1 |
| Konstantinov, IE | 1 |
| Shimizu, M | 1 |
| Li, J | 1 |
| Cheung, M | 1 |
| White, PA | 1 |
| Kristiansen, SB | 1 |
| Sorensen, K | 1 |
| Dzavik, V | 1 |
| Redington, AN | 1 |
| Kharbanda, RK | 1 |
| Pompermayer, K | 1 |
| Amaral, FA | 1 |
| Fagundes, CT | 1 |
| Vieira, AT | 1 |
| Cunha, FQ | 1 |
| Teixeira, MM | 1 |
| Souza, DG | 1 |
| Kimura, T | 1 |
| Takagi, H | 1 |
| Suzuma, K | 1 |
| Kita, M | 1 |
| Watanabe, D | 1 |
| Yoshimura, N | 1 |
| Loukogeorgakis, SP | 1 |
| Williams, R | 1 |
| Panagiotidou, AT | 1 |
| Kolvekar, SK | 1 |
| Donald, A | 1 |
| Cole, TJ | 1 |
| Yellon, DM | 1 |
| Deanfield, JE | 1 |
| MacAllister, RJ | 1 |
| Minkes, RK | 1 |
| Santiago, JA | 1 |
| McMahon, TJ | 1 |
| Kadowitz, PJ | 1 |
| Khimenko, PL | 1 |
| Moore, TM | 1 |
| Taylor, AE | 1 |
| Reeves, WB | 1 |
| Shah, SV | 1 |
| Weselcouch, EO | 1 |
| Sargent, C | 1 |
| Wilde, MW | 1 |
| Smith, MA | 1 |
| Vallet, B | 1 |
| Guery, B | 1 |
| Mangalaboyi, J | 1 |
| Menager, P | 1 |
| Curtis, SE | 1 |
| Cain, SM | 1 |
| Chopin, C | 1 |
| Dupuis, BA | 1 |
| Bijlstra, PJ | 1 |
| den Arend, JA | 1 |
| Lutterman, JA | 2 |
| Russel, FG | 3 |
| Thien, T | 1 |
| Smits, P | 3 |
| Pang, CY | 1 |
| Neligan, P | 1 |
| Zhong, A | 1 |
| He, W | 1 |
| Xu, H | 1 |
| Forrest, CR | 1 |
| Tamai, K | 1 |
| Suzuki, H | 1 |
| Shirai, S | 1 |
| Ogura, Y | 1 |
| Engbersen, R | 1 |
| Moons, MM | 1 |
| Wouterse, AC | 1 |
| Dijkman, HB | 1 |
| Kramers, C | 1 |
| Huh, J | 1 |
| Gross, GJ | 1 |
| Nagase, H | 1 |
| Liang, BT | 1 |
| Spallarossa, P | 1 |
| Schiavo, M | 1 |
| Rossettin, P | 1 |
| Cordone, S | 1 |
| Olivotti, L | 1 |
| Cordera, R | 1 |
| Brunelli, C | 1 |
| Simões, C | 1 |
| Svensjö, E | 1 |
| Bouskela, E | 1 |
| Abbink, EJ | 1 |
| Pickkers, P | 1 |
| van Rosendaal, AJ | 1 |
| Tack, CJ | 1 |
| Dickson, EW | 1 |
| Tubbs, RJ | 1 |
| Porcaro, WA | 1 |
| Lee, WJ | 1 |
| Blehar, DJ | 1 |
| Carraway, RE | 1 |
| Darling, CE | 1 |
| Przyklenk, K | 1 |
| Zhang, HL | 1 |
| Li, YS | 1 |
| Fu, SX | 1 |
| Yang, XP | 1 |
| Daut, J | 1 |
| Maier-Rudolph, W | 1 |
| von Beckerath, N | 1 |
| Mehrke, G | 1 |
| Günther, K | 1 |
| Goedel-Meinen, L | 1 |
| Idahl, LA | 2 |
| Hurme, P | 1 |
| Wahlquist, Y | 1 |
| Hellman, B | 2 |
| Danielsson, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Remote Preconditioning in Primary Percutaneous Intervention of Acute ST Elevation Myocardial Infarction[NCT00435266] | Phase 2/Phase 3 | 250 participants (Anticipated) | Interventional | 2007-02-28 | Completed | ||
| Remote Ischemic Preconditioning in Head and Neck Cancer Reconstruction - A Randomized Controlled Trial[NCT02548377] | 60 participants (Actual) | Interventional | 2015-09-29 | Completed | |||
| A Randomised Controlled Trial of the Effect of Remote Ischaemic Conditioning on Coronary Endothelial Function in Patients With Angina.[NCT02666235] | Phase 2 | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals[NCT05423470] | 41 participants (Actual) | Interventional | 2019-05-30 | Completed | |||
| The Effect of Remote Ischemic Conditioning (RIC) on Inflammatory Biomarkers and Outcomes in Patients With TBI[NCT03899532] | 120 participants (Anticipated) | Interventional | 2019-09-24 | Recruiting | |||
| The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery in Patients at a High Risk of Cardiac Events[NCT05733208] | 766 participants (Anticipated) | Interventional | 2023-05-06 | Recruiting | |||
| Is Augmentation of PORH by Rosuvastatin Adenosine-receptor Mediated?[NCT00851175] | Phase 4 | 8 participants (Anticipated) | Interventional | 2009-03-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 trials available for glyburide and Ischemia
| Article | Year |
|---|---|
Acute effects of glibenclamide on reactive hyperaemia in the lower limbs in humans.
Topics: Adult; Area Under Curve; Female; Glyburide; Humans; Hyperemia; Ischemia; Ischemic Preconditioning; L | 2002 |
Forearm vascular reactivity is differentially influenced by gliclazide and glibenclamide in chronically treated type 2 diabetic patients.
Topics: Adult; Analysis of Variance; Cross-Over Studies; Diabetes Mellitus, Type 2; Dose-Response Relationsh | 2005 |
Blockade of vascular ATP-sensitive potassium channels reduces the vasodilator response to ischaemia in humans.
Topics: Adenosine Triphosphate; Adult; Forearm; Glyburide; Hemodynamics; Humans; Hypoglycemic Agents; Infusi | 1996 |
Sulfonylurea treatment of type 2 diabetic patients does not reduce the vasodilator response to ischemia.
Topics: Aged; Aged, 80 and over; Blood Pressure; Brachial Artery; Diabetes Mellitus, Type 2; Diet, Diabetic; | 2001 |
27 other studies available for glyburide and Ischemia
| Article | Year |
|---|---|
Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Vessels; Death, Sudden, Cardiac; Decanoic Acids; Female; G | 2012 |
Na(+)-H+ exchange inhibition attenuates ischemic injury in rat random pattern skin flap: the role of mitochondrial ATP-sensitive potassium channels.
Topics: Amiloride; Animals; Dermatologic Surgical Procedures; Diazoxide; Glyburide; Ion Channel Gating; Isch | 2013 |
Ischemic shortening of action potential duration as a result of KATP channel opening attenuates myocardial stunning by reducing calcium influx.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Coronary Vess | 2002 |
Lung endothelial cell proliferation with decreased shear stress is mediated by reactive oxygen species.
Topics: Angiotensin II; Animals; Apoptosis; Cell Division; Endothelial Cells; Glyburide; Hypoglycemic Agents | 2006 |
Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes.
Topics: Aniline Compounds; Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gliclazi | 2005 |
Levosimendan protects against experimental endotoxemic acute renal failure.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Anti-Inflammatory Agents; Cardiotonic Agents; | 2006 |
ATP-sensitive potassium channels mediate the anti-ischemic properties of ischemic and pharmacologic preconditioning in rat random-pattern skin flap.
Topics: Adenosine; Adenosine Triphosphate; Animals; Dermatologic Surgical Procedures; Diazoxide; Glyburide; | 2006 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Effects of the treatment with glibenclamide, an ATP-sensitive potassium channel blocker, on intestinal ischemia and reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Capillary Permeability; Chemotaxis, Leukocyte; Cytokines; Glyburide | 2007 |
Comparisons between the beneficial effects of different sulphonylurea treatments on ischemia-induced retinal neovascularization.
Topics: Acetylcysteine; Animals; Blood Glucose; Female; Gliclazide; Glyburide; Ischemia; Mice; Oxidative Str | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Role of K+ATP channels and EDRF in reactive hyperemia in the hindquarters vascular bed of cats.
Topics: Adamantane; Adenosine Triphosphate; Animals; Arginine; Cats; Glyburide; Hindlimb; Hyperemia; Ischemi | 1995 |
ATP-sensitive K+ channels are not involved in ischemia-reperfusion lung endothelial injury.
Topics: Adenosine; Adenosine Triphosphate; Animals; Benzopyrans; Capillary Permeability; Cromakalim; Endothe | 1995 |
Activation of potassium channels contributes to hypoxic injury in proximal tubules.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Diazoxide; DNA Damage; Dose-Response Relation | 1994 |
ATP-sensitive potassium channels and skeletal muscle function in vitro.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; Energy Metabolism; Gallamine Triethiodide; G | 1993 |
Critical oxygen extraction in piglet hindlimb is impaired after inhibition of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hindlimb; Hypoxia; Ischemia; Muscle, Smooth, Vascular; O | 1996 |
Effector mechanism of adenosine in acute ischemic preconditioning of skeletal muscle against infarction.
Topics: Adenosine; Animals; Decanoic Acids; Glyburide; Hydroxy Acids; Infarction; Ischemia; Ischemic Precond | 1997 |
Role of endothelium-derived vasodilators and K(+) channels in ischemic vasodilation of guinea-pig choroidal arterioles.
Topics: Animals; Arterioles; Charybdotoxin; Choroid; Endothelium, Vascular; Enzyme Inhibitors; Glucose; Glyb | 1999 |
Sulphonylurea drugs reduce hypoxic damage in the isolated perfused rat kidney.
Topics: Analysis of Variance; Animals; ATP-Binding Cassette Transporters; Glyburide; Hypoglycemic Agents; In | 2000 |
Protection of cardiac myocytes via delta(1)-opioid receptors, protein kinase C, and mitochondrial K(ATP) channels.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Benzylidene Compounds; Cells, Cult | 2001 |
Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion.
Topics: Adenosine Triphosphate; Animals; Arterioles; Capillary Permeability; Cheek; Cricetinae; Cromakalim; | 2002 |
Vascular K(ATP) channel blockade by glibenclamide, but not by acarbose, in patients with Type II diabetes.
Topics: Acarbose; Acetylcholine; Cross-Over Studies; Diabetes Mellitus, Type 2; Diazoxide; Dipyridamole; Dou | 2002 |
Myocardial preconditioning factors evoke mesenteric ischemic tolerance via opioid receptors and K(ATP) channels.
Topics: Animals; Chromatography, High Pressure Liquid; Glyburide; In Vitro Techniques; Ischemia; Ischemic Pr | 2002 |
Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; Hyp | 1991 |
Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Bradykinin; Coronary Vessels; | 1990 |
Pancreatic -cell function and content of 6-phosphogluconate.
Topics: Animals; Butyrates; Calcium; Cyclic AMP; Epinephrine; Female; Gluconates; Glucose; Glucosephosphates | 1971 |
Levels of -ketoglutarate and glutamate in stimulated pancreatic -cells.
Topics: Animals; Carbutamide; Chemical Phenomena; Chemistry; Depression, Chemical; Diazoxide; Female; Fluoro | 1970 |