glyburide has been researched along with Intracranial Hemorrhages in 4 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Intracranial Hemorrhages: Bleeding within the SKULL, including hemorrhages in the brain and the three membranes of MENINGES. The escape of blood often leads to the formation of HEMATOMA in the cranial epidural, subdural, and subarachnoid spaces.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Blockade of this channel by the small molecule glyburide results in improved survival and neurological outcome in multiple preclinical models of ischemic stroke." | 8.93 | Human Data Supporting Glyburide in Ischemic Stroke. ( Elm, J; Kimberly, WT; Kronenberg, G; Kunte, H; Sheth, KN; Simard, JM, 2016) |
| " Blockade of this channel by the small molecule glyburide results in improved survival and neurological outcome in multiple preclinical models of ischemic stroke." | 4.93 | Human Data Supporting Glyburide in Ischemic Stroke. ( Elm, J; Kimberly, WT; Kronenberg, G; Kunte, H; Sheth, KN; Simard, JM, 2016) |
| "Using a transient middle cerebral artery occlusion (tMCAo) rodent model of stroke, we studied two rat cohorts, one without rt-PA and a second cohort treated with rt-PA." | 1.62 | Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion. ( Igarashi, T; Kimberly, WT; Sastre, C; Wolcott, Z, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (75.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Igarashi, T | 1 |
| Sastre, C | 1 |
| Wolcott, Z | 1 |
| Kimberly, WT | 2 |
| Ding, J | 1 |
| Yuan, F | 1 |
| Guo, JY | 1 |
| Chen, H | 1 |
| Tian, HL | 1 |
| Khanna, A | 1 |
| Walcott, BP | 1 |
| Kahle, KT | 1 |
| Simard, JM | 2 |
| Sheth, KN | 1 |
| Elm, J | 1 |
| Kronenberg, G | 1 |
| Kunte, H | 1 |
2 reviews available for glyburide and Intracranial Hemorrhages
| Article | Year |
|---|---|
Effect of glibenclamide on the prevention of secondary brain injury following ischemic stroke in humans.
Topics: Brain Diseases; Brain Edema; Brain Ischemia; Clinical Trials, Phase II as Topic; Glyburide; Humans; | 2014 |
Human Data Supporting Glyburide in Ischemic Stroke.
Topics: Brain Edema; Fibrinolytic Agents; Glyburide; Humans; Hypoglycemic Agents; Intracranial Hemorrhages; | 2016 |
2 other studies available for glyburide and Intracranial Hemorrhages
| Article | Year |
|---|---|
Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion.
Topics: Animals; Brain Edema; Disease Models, Animal; Fibrinolytic Agents; Glyburide; Infarction, Middle Cer | 2021 |
Influence of glibenclamide on outcome in patients with type 2 diabetes and traumatic brain injury.
Topics: Adult; Age Factors; Aged; Blood Glucose; Brain Injuries; Diabetes Mellitus, Type 2; Female; Glasgow | 2013 |