glyburide has been researched along with Injury, Ischemia-Reperfusion in 54 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It has been shown that nicorandil, which has both ATP-sensitive K+ (KATP) channel opener-like and nitrate-like properties, has an organ-protective effect in ischemia-reperfusion injury in several experimental animal models." | 7.77 | The effect of nicorandil on small intestinal ischemia-reperfusion injury in a canine model. ( Arakawa, K; Matsumoto, K; Oshima, K; Sato, H; Suto, Y; Takeyoshi, I; Yamazaki, H, 2011) |
| "Landiolol, a highly cardioselective beta1-blocker, has cardioprotective effects against ischemia-reperfusion injury, although the precise mechanism is still unclear." | 7.74 | Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway. ( Hirai, H; Minamiyama, Y; Sakaguchi, M; Sasaki, Y; Shibata, T; Suehiro, S; Takahashi, Y; Takemura, S, 2007) |
| "We studied changes in arteriolar and venular diameters and macromolecular leakage altered by ischemia/reperfusion (I/R) and topically applied histamine after I/R and how these changes were modulated by cromakalim (KATP-channel opener) and glibenclamide (KATP-channel blocker)." | 7.71 | Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion. ( Bouskela, E; Simões, C; Svensjö, E, 2002) |
| "53." | 5.34 | Hydrogen sulfide contributes to cardioprotection during ischemia-reperfusion injury by opening K ATP channels. ( Huang, H; Liu, P; Tang, C; Wang, J; Zhang, Z, 2007) |
| "It has been shown that nicorandil, which has both ATP-sensitive K+ (KATP) channel opener-like and nitrate-like properties, has an organ-protective effect in ischemia-reperfusion injury in several experimental animal models." | 3.77 | The effect of nicorandil on small intestinal ischemia-reperfusion injury in a canine model. ( Arakawa, K; Matsumoto, K; Oshima, K; Sato, H; Suto, Y; Takeyoshi, I; Yamazaki, H, 2011) |
| "Landiolol, a highly cardioselective beta1-blocker, has cardioprotective effects against ischemia-reperfusion injury, although the precise mechanism is still unclear." | 3.74 | Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway. ( Hirai, H; Minamiyama, Y; Sakaguchi, M; Sasaki, Y; Shibata, T; Suehiro, S; Takahashi, Y; Takemura, S, 2007) |
| " We examined KATP channel modulation in renal ischemia-reperfusion injury (IRI), using an isolated perfused rat kidney (IPRK) model, in control, IRI, IRI+200 microM diazoxide (a KATP opener), IRI + 10 microM glibenclamide (a KATP blocker) and IRI + 200 microM diazoxide + 10 microM glibenclamide groups." | 3.72 | ATP-dependent K+ channels in renal ischemia reperfusion injury. ( Endre, ZH; Gobé, GC; Rahgozar, M; Willgoss, DA, 2003) |
| "We studied changes in arteriolar and venular diameters and macromolecular leakage altered by ischemia/reperfusion (I/R) and topically applied histamine after I/R and how these changes were modulated by cromakalim (KATP-channel opener) and glibenclamide (KATP-channel blocker)." | 3.71 | Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion. ( Bouskela, E; Simões, C; Svensjö, E, 2002) |
| "In the present study, interaction of the ATP-sensitive K+-channel blocker glibenclamide with enantiomers of the antihypertensive drug, cicletanine, was studied on ischaemic myocardial function, lactate-dehydrogenase (LDH) release, and early reperfusion-induced ventricular fibrillation (VF)." | 3.70 | Cardioprotective effect of enantiomers of cicletanine (BN50417, BN50418) in ischaemic/reperfused isolated working rat hearts: interaction with glibenclamide. ( Csont, T; Droy-lefaix, MT; Ferdinandy, P; Koltai, M; Szilvássy, Z, 1999) |
| "Using a transient middle cerebral artery occlusion (tMCAo) rodent model of stroke, we studied two rat cohorts, one without rt-PA and a second cohort treated with rt-PA." | 1.62 | Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion. ( Igarashi, T; Kimberly, WT; Sastre, C; Wolcott, Z, 2021) |
| "Diabetic nephropathy is one of the important microvascular complications of diabetes; however, the main problem remains is the control of progression of nephropathy in diabetes." | 1.39 | Chebulic acid attenuates ischemia reperfusion induced biochemical alteration in diabetic rats. ( Gupta, VB; Silawat, N, 2013) |
| " In resistance vessels, venous occlusion plethysmography was used to measure the dilator response to acetylcholine (ACh) [area under ACh dose-response curve (ACh AUC)]." | 1.37 | Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore. ( Bhavsar, DD; Charakida, M; Deanfield, JE; Loukogeorgakis, SP; MacAllister, RJ; Okorie, MI; Ridout, D, 2011) |
| "Diadenosine tetraphosphate (AP4A) is a vasoactive mediator that may be released from platelet granules and that may reach higher plasma concentrations during coronary ischemia-reperfusion." | 1.37 | Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart. ( Diéguez, G; Fernández, N; García-Villalón, AL; Monge, L, 2011) |
| "In fact, severe ischemia reperfusion injury can significantly reduce graft survival, even with modern immunosuppressive agents." | 1.35 | Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia. ( Chilton, L; Figura, M; Giles, WR; Knight, D; Kubes, P; Liacini, A; Millar, TM; Patel, K; Phan, V; Tibbles, LA; Viskovic, MM, 2009) |
| "Propofol treatments were initiated at various time intervals: 1 or 24 h before ischemia, only during ischemia, or only during reperfusion." | 1.35 | The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion. ( Assad, AR; Capella, MA; Delou, JM; Fonseca, LM; Lopes, AG; Nascimento, JH; Verçosa, N; Villela, NR, 2009) |
| "Isoflurane was applied after OGD." | 1.35 | Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. ( Jung, HH; Lee, JJ; Li, L; Zuo, Z, 2008) |
| "Intestinal ischemia and reperfusion injury is dependent on the recruitment and activation of neutrophils." | 1.34 | Effects of the treatment with glibenclamide, an ATP-sensitive potassium channel blocker, on intestinal ischemia and reperfusion injury. ( Amaral, FA; Cunha, FQ; Fagundes, CT; Pompermayer, K; Souza, DG; Teixeira, MM; Vieira, AT, 2007) |
| "53." | 1.34 | Hydrogen sulfide contributes to cardioprotection during ischemia-reperfusion injury by opening K ATP channels. ( Huang, H; Liu, P; Tang, C; Wang, J; Zhang, Z, 2007) |
| "In this study, we determined whether repeated brief isoflurane (Iso) anesthesia induces ischemic tolerance to focal cerebral ischemia in a dose-response manner and whether the effect is dependent on adenosine triphosphate-regulated potassium channels." | 1.32 | Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats. ( Hou, L; Lu, Z; Wu, M; Xiong, L; Zhang, X; Zheng, Y; Zhu, Z, 2003) |
| "Pretreatment with WEB 2086 (5 x 10(-7) M) warded off nearly all damage caused by hypoxia/reoxygenation." | 1.31 | The role of platelet-activating factor (PAF) antagonists and nitric oxide in cardiac actions of PAF. Electrophysiological and morphological study. ( Balogh, I; Kecskeméti, V, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (20.37) | 18.2507 |
| 2000's | 27 (50.00) | 29.6817 |
| 2010's | 14 (25.93) | 24.3611 |
| 2020's | 2 (3.70) | 2.80 |
| Authors | Studies |
|---|---|
| Granado, M | 1 |
| González-Hedström, D | 1 |
| Amor, S | 1 |
| Fajardo-Vidal, A | 1 |
| Villalva, M | 1 |
| de la Fuente-Fernández, M | 1 |
| Tejera-Muñoz, A | 1 |
| Jaime, L | 1 |
| Santoyo, S | 1 |
| García-Villalón, AL | 2 |
| Igarashi, T | 1 |
| Sastre, C | 1 |
| Wolcott, Z | 1 |
| Kimberly, WT | 1 |
| Teng, X | 1 |
| Chen, W | 1 |
| Liu, Z | 1 |
| Feng, T | 1 |
| Li, H | 1 |
| Ding, S | 1 |
| Chen, Y | 1 |
| Zhang, Y | 2 |
| Tang, X | 1 |
| Geng, D | 1 |
| Shimizu, S | 1 |
| Oikawa, R | 1 |
| Tsounapi, P | 1 |
| Inoue, K | 1 |
| Shimizu, T | 1 |
| Tanaka, K | 1 |
| Martin, DT | 1 |
| Honda, M | 1 |
| Sejima, T | 1 |
| Tomita, S | 1 |
| Saito, M | 1 |
| Dudek, M | 1 |
| Knutelska, J | 1 |
| Bednarski, M | 1 |
| Nowiński, L | 1 |
| Zygmunt, M | 1 |
| Bilska-Wilkosz, A | 1 |
| Iciek, M | 1 |
| Otto, M | 1 |
| Żytka, I | 1 |
| Sapa, J | 1 |
| Włodek, L | 1 |
| Filipek, B | 1 |
| Mehrjerdi, FZ | 1 |
| Aboutaleb, N | 1 |
| Pazoki-Toroudi, H | 3 |
| Soleimani, M | 3 |
| Ajami, M | 3 |
| Khaksari, M | 1 |
| Safari, F | 1 |
| Habibey, R | 3 |
| Hesami, A | 1 |
| Figura, M | 1 |
| Chilton, L | 1 |
| Liacini, A | 1 |
| Viskovic, MM | 1 |
| Phan, V | 1 |
| Knight, D | 1 |
| Millar, TM | 1 |
| Patel, K | 1 |
| Kubes, P | 1 |
| Giles, WR | 1 |
| Tibbles, LA | 1 |
| Yousif, MH | 1 |
| Benter, IF | 1 |
| Roman, RJ | 1 |
| Assad, AR | 1 |
| Delou, JM | 1 |
| Fonseca, LM | 1 |
| Villela, NR | 1 |
| Nascimento, JH | 1 |
| Verçosa, N | 1 |
| Lopes, AG | 1 |
| Capella, MA | 1 |
| Zarch, AV | 1 |
| Toroudi, HP | 1 |
| Bakhtiarian, A | 1 |
| Katebi, M | 1 |
| Djahanguiri, B | 1 |
| Yamazaki, H | 2 |
| Oshima, K | 2 |
| Sato, H | 3 |
| Kobayashi, K | 1 |
| Suto, Y | 2 |
| Hirai, K | 1 |
| Odawara, H | 1 |
| Matsumoto, K | 2 |
| Takeyoshi, I | 2 |
| Voitychuk, OI | 1 |
| Strutynskyi, RB | 1 |
| Yagupolskii, LM | 1 |
| Tinker, A | 1 |
| Moibenko, OO | 1 |
| Shuba, YM | 1 |
| Abdallah, DM | 1 |
| Nassar, NN | 1 |
| Abd-El-Salam, RM | 1 |
| Arakawa, K | 1 |
| Okorie, MI | 1 |
| Bhavsar, DD | 1 |
| Ridout, D | 1 |
| Charakida, M | 1 |
| Deanfield, JE | 2 |
| Loukogeorgakis, SP | 2 |
| MacAllister, RJ | 2 |
| Fernández, N | 1 |
| Monge, L | 1 |
| Diéguez, G | 1 |
| Ha, SJ | 1 |
| Kim, W | 1 |
| Woo, JS | 1 |
| Kim, JB | 1 |
| Kim, SJ | 1 |
| Kim, WS | 1 |
| Kim, MK | 1 |
| Cheng, XW | 1 |
| Kim, KS | 1 |
| Hsu, CY | 1 |
| Fang, SY | 1 |
| Chen, YZ | 1 |
| Roan, JN | 1 |
| Chang, SW | 1 |
| Huang, CC | 1 |
| Liu, YC | 1 |
| Lam, CF | 1 |
| Tsai, YC | 1 |
| Silawat, N | 1 |
| Gupta, VB | 1 |
| Farahini, H | 1 |
| Davoodi, SH | 1 |
| Azad, N | 1 |
| Tavakkoli-Hosseini, M | 1 |
| Lascano, EC | 1 |
| Negroni, JA | 1 |
| del Valle, HF | 1 |
| Xiong, L | 1 |
| Zheng, Y | 1 |
| Wu, M | 1 |
| Hou, L | 1 |
| Zhu, Z | 1 |
| Zhang, X | 1 |
| Lu, Z | 1 |
| Zhu, HF | 1 |
| Dong, JW | 1 |
| Zhu, WZ | 1 |
| Ding, HL | 1 |
| Zhou, ZN | 1 |
| Rahgozar, M | 1 |
| Willgoss, DA | 1 |
| Gobé, GC | 1 |
| Endre, ZH | 1 |
| Bruce, J | 1 |
| Taggart, M | 1 |
| Austin, C | 1 |
| Pompermayer, K | 2 |
| Souza, DG | 2 |
| Lara, GG | 1 |
| Silveira, KD | 1 |
| Cassali, GD | 1 |
| Andrade, AA | 1 |
| Bonjardim, CA | 1 |
| Passaglio, KT | 1 |
| Assreuy, J | 1 |
| Cunha, FQ | 2 |
| Vieira, MA | 1 |
| Teixeira, MM | 2 |
| Kandilci, HB | 1 |
| Gümüşel, B | 1 |
| Demiryürek, AT | 1 |
| Lippton, H | 1 |
| Amaral, FA | 1 |
| Fagundes, CT | 1 |
| Vieira, AT | 1 |
| Takahashi, Y | 1 |
| Takemura, S | 1 |
| Minamiyama, Y | 1 |
| Shibata, T | 1 |
| Hirai, H | 1 |
| Sasaki, Y | 1 |
| Sakaguchi, M | 1 |
| Suehiro, S | 1 |
| Coelho, FR | 1 |
| Cavriani, G | 1 |
| Soares, AL | 1 |
| Teixeira, SA | 1 |
| Almeida, PC | 1 |
| Sudo-Hayashi, LS | 1 |
| Muscará, MN | 1 |
| Oliveira-Filho, RM | 1 |
| Vargaftig, BB | 1 |
| Tavares-de-Lima, W | 1 |
| Birkenmeier, K | 1 |
| Staudt, A | 1 |
| Schunck, WH | 1 |
| Janke, I | 1 |
| Labitzke, C | 1 |
| Prange, T | 1 |
| Trimpert, C | 1 |
| Krieg, T | 1 |
| Landsberger, M | 1 |
| Stangl, V | 1 |
| Felix, SB | 1 |
| Williams, R | 1 |
| Panagiotidou, AT | 1 |
| Kolvekar, SK | 1 |
| Donald, A | 1 |
| Cole, TJ | 1 |
| Yellon, DM | 1 |
| Yonezawa, D | 1 |
| Sekiguchi, F | 1 |
| Miyamoto, M | 1 |
| Taniguchi, E | 1 |
| Honjo, M | 1 |
| Masuko, T | 1 |
| Nishikawa, H | 1 |
| Kawabata, A | 1 |
| Vajda, S | 1 |
| Baczkó, I | 1 |
| Leprán, I | 1 |
| Zhang, Z | 1 |
| Huang, H | 1 |
| Liu, P | 1 |
| Tang, C | 1 |
| Wang, J | 1 |
| Lee, JJ | 1 |
| Li, L | 1 |
| Jung, HH | 1 |
| Zuo, Z | 1 |
| Piana, RN | 1 |
| Shafique, T | 1 |
| Dai, HB | 1 |
| Sellke, FW | 1 |
| Khimenko, PL | 1 |
| Moore, TM | 1 |
| Taylor, AE | 1 |
| Grover, GJ | 1 |
| Sleph, PG | 1 |
| Dzwonczyk, S | 1 |
| McCullough, JR | 1 |
| McPherson, CD | 1 |
| Pierce, GN | 1 |
| Cole, WC | 1 |
| Louis, TM | 1 |
| Meng, W | 1 |
| Bari, F | 1 |
| Errico, RA | 1 |
| Busija, DW | 1 |
| Zhao, ZQ | 1 |
| Todd, JC | 1 |
| Ma, XL | 1 |
| Vinten-Johansen, J | 1 |
| Bouskela, E | 2 |
| Cyrino, FZ | 1 |
| Conde, CM | 1 |
| Garcia, AA | 1 |
| Jovanovic, A | 1 |
| Jovanovic, S | 1 |
| Carrasco, AJ | 1 |
| Terzic, A | 1 |
| Ferdinandy, P | 1 |
| Szilvássy, Z | 1 |
| Csont, T | 1 |
| Koltai, M | 1 |
| Droy-lefaix, MT | 1 |
| Yang, SP | 1 |
| Hao, YB | 1 |
| Wu, YX | 1 |
| Dun, W | 1 |
| Shen, LH | 1 |
| Tanonaka, K | 1 |
| Taguchi, T | 1 |
| Koshimizu, M | 1 |
| Ando, T | 1 |
| Morinaka, T | 1 |
| Yogo, T | 1 |
| Konishi, F | 1 |
| Takeo, S | 1 |
| Reshef, A | 2 |
| Sperling, O | 2 |
| Zoref-Shani, E | 2 |
| Capua, ND | 1 |
| Lee, HT | 1 |
| Emala, CW | 1 |
| Kecskeméti, V | 1 |
| Balogh, I | 1 |
| Simões, C | 1 |
| Svensjö, E | 1 |
| Fukuse, T | 1 |
| Hirata, T | 1 |
| Omasa, M | 1 |
| Wada, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomised Controlled Trial of the Effect of Remote Ischaemic Conditioning on Coronary Endothelial Function in Patients With Angina.[NCT02666235] | Phase 2 | 60 participants (Actual) | Interventional | 2011-07-31 | Completed | ||
| Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals[NCT05423470] | 41 participants (Actual) | Interventional | 2019-05-30 | Completed | |||
| The Effect of Remote Ischemic Conditioning (RIC) on Inflammatory Biomarkers and Outcomes in Patients With TBI[NCT03899532] | 120 participants (Anticipated) | Interventional | 2019-09-24 | Recruiting | |||
| The Effect of Remote Ischemic Preconditioning on Myocardial Injury After Noncardiac Surgery in Patients at a High Risk of Cardiac Events[NCT05733208] | 766 participants (Anticipated) | Interventional | 2023-05-06 | Recruiting | |||
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 trial available for glyburide and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Preventive effects of exenatide on endothelial dysfunction induced by ischemia-reperfusion injury via KATP channels.
Topics: Adult; Brachial Artery; Cross-Over Studies; Double-Blind Method; Endothelium, Vascular; Exenatide; F | 2012 |
53 other studies available for glyburide and Injury, Ischemia-Reperfusion
| Article | Year |
|---|---|
Marjoram extract prevents ischemia reperfusion-induced myocardial damage and exerts anti-contractile effects in aorta segments of male wistar rats.
Topics: Animals; Aorta; Calcium Channel Agonists; Calcium Channels; Endothelin-1; Glyburide; Male; Myocardia | 2022 |
Continuous Glibenclamide Prevents Hemorrhagic Transformation in a Rodent Model of Severe Ischemia-Reperfusion.
Topics: Animals; Brain Edema; Disease Models, Animal; Fibrinolytic Agents; Glyburide; Infarction, Middle Cer | 2021 |
NLRP3 Inflammasome Is Involved in Q-VD-OPH Induced Necroptosis Following Cerebral Ischemia-Reperfusion Injury.
Topics: Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Brain Ischemia; Glyburide; Inflammasomes; Male; | 2018 |
Blocking of the ATP sensitive potassium channel ameliorates the ischaemia-reperfusion injury in the rat testis.
Topics: Animals; Apoptosis; Cromakalim; Decanoic Acids; Diazoxide; Glyburide; Hydroxy Acids; KATP Channels; | 2014 |
Alpha lipoic acid protects the heart against myocardial post ischemia-reperfusion arrhythmias via KATP channel activation in isolated rat hearts.
Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase, Mitochondrial; Animals; Antioxidants; Arrhythmias, C | 2014 |
The Protective Effect of Remote Renal Preconditioning Against Hippocampal Ischemia Reperfusion Injury: Role of KATP Channels.
Topics: Animals; Apoptosis; Catalase; Decanoic Acids; Glyburide; Hippocampus; Hydroxy Acids; Ischemic Precon | 2015 |
The mechanism of preventive effect of captopril on renal ischemia reperfusion injury is independent of ATP dependent potassium channels.
Topics: Animals; Captopril; Dose-Response Relationship, Drug; Glyburide; KATP Channels; Kidney; Male; Rats; | 2008 |
Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia.
Topics: Animals; Cats; Cell Membrane; Endothelium, Vascular; Gelatin; Glyburide; Humans; Hypoxia; KATP Chann | 2009 |
Cytochrome P450 metabolites of arachidonic acid play a role in the enhanced cardiac dysfunction in diabetic rats following ischaemic reperfusion injury.
Topics: 8,11,14-Eicosatrienoic Acid; Amidines; Animals; Arachidonic Acid; Blood Glucose; Body Weight; Corona | 2009 |
The role of KATP channels on propofol preconditioning in a cellular model of renal ischemia-reperfusion.
Topics: Adenosine Triphosphate; Animals; Antimycin A; Apoptosis; Cell Survival; Cytoprotection; Decanoic Aci | 2009 |
Neuroprotective effects of diazoxide and its antagonism by glibenclamide in pyramidal neurons of rat hippocampus subjected to ischemia-reperfusion-induced injury.
Topics: Animals; bcl-2-Associated X Protein; Blotting, Western; Cell Death; Diazoxide; Diuretics; Gene Expre | 2009 |
The effect of nicorandil on ischemia-reperfusion injury in a porcine total hepatic vascular exclusion model.
Topics: Animals; Aspartate Aminotransferases; Glyburide; KATP Channels; L-Lactate Dehydrogenase; Liver; Mode | 2011 |
Sarcolemmal cardiac K(ATP) channels as a target for the cardioprotective effects of the fluorine-containing pinacidil analogue, flocalin.
Topics: Animals; Cardiotonic Agents; Cells, Cultured; Fluorine; Glyburide; Guinea Pigs; Heart; HEK293 Cells; | 2011 |
Glibenclamide ameliorates ischemia-reperfusion injury via modulating oxidative stress and inflammatory mediators in the rat hippocampus.
Topics: Animals; Glyburide; Hippocampus; Inflammation Mediators; Male; Oxidative Stress; Random Allocation; | 2011 |
The effect of nicorandil on small intestinal ischemia-reperfusion injury in a canine model.
Topics: Animals; Disease Models, Animal; Dogs; Female; Glyburide; Intestine, Small; KATP Channels; Male; Mes | 2011 |
Postconditioning protects against human endothelial ischaemia-reperfusion injury via subtype-specific KATP channel activation and is mimicked by inhibition of the mitochondrial permeability transition pore.
Topics: Acetylcholine; Adult; Analysis of Variance; Brachial Artery; Cyclosporine; Endothelium, Vascular; Fe | 2011 |
Coronary response to diadenosine tetraphosphate after ischemia-reperfusion in the isolated rat heart.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Androstadienes; Animals; Coronar | 2011 |
Cardiovascular protection of activating KATP channel during ischemia-reperfusion acidosis.
Topics: Acidosis; Adamantane; Animals; Aorta, Abdominal; Calcium; Dose-Response Relationship, Drug; Glyburid | 2012 |
Chebulic acid attenuates ischemia reperfusion induced biochemical alteration in diabetic rats.
Topics: Animals; Benzopyrans; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Dose-Response Relatio | 2013 |
Late anti-apoptotic effect of K(ATP) channel opening in skeletal muscle.
Topics: Animals; Apoptosis; bcl-2-Associated X Protein; Catalase; Cell Nucleus; Diazoxide; DNA Fragmentation | 2012 |
Ischemic shortening of action potential duration as a result of KATP channel opening attenuates myocardial stunning by reducing calcium influx.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Coronary Vess | 2002 |
Preconditioning with isoflurane produces dose-dependent neuroprotection via activation of adenosine triphosphate-regulated potassium channels after focal cerebral ischemia in rats.
Topics: Anesthetics, Inhalation; Animals; ATP-Binding Cassette Transporters; Blood Gas Analysis; Body Temper | 2003 |
ATP-dependent potassium channels involved in the cardiac protection induced by intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Calcium; Decanoic Acids; Glyburide; Heart Ventricles; Hemodynamics; Hydroxy Acids; Hypoxia; | 2003 |
ATP-dependent K+ channels in renal ischemia reperfusion injury.
Topics: Acute Kidney Injury; Adenosine Triphosphate; Animals; Cromakalim; Diazoxide; Disease Models, Animal; | 2003 |
Contractile responses of isolated rat mesenteric arteries to acute episodes of severe hypoxia and subsequent reoxygenation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Adenosine Triph | 2004 |
The ATP-sensitive potassium channel blocker glibenclamide prevents renal ischemia/reperfusion injury in rats.
Topics: Adenosine Triphosphate; Animals; Cytokines; Diazoxide; Disease Models, Animal; Glyburide; Interleuki | 2005 |
Preconditioning modulates pulmonary endothelial dysfunction following ischemia-reperfusion injury in the rat lung: role of potassium channels.
Topics: Acetylcholine; Animals; Anti-Arrhythmia Agents; Benzamides; Decanoic Acids; Endothelium, Vascular; G | 2006 |
Effects of the treatment with glibenclamide, an ATP-sensitive potassium channel blocker, on intestinal ischemia and reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Capillary Permeability; Chemotaxis, Leukocyte; Cytokines; Glyburide | 2007 |
Landiolol has cardioprotective effects against reperfusion injury in the rat heart via the PKCepsilon signaling pathway.
Topics: Adrenergic beta-Antagonists; Alkaloids; Animals; Benzophenanthridines; Cardiotonic Agents; Glyburide | 2007 |
Lymphatic-borne IL-1beta and the inducible isoform of nitric oxide synthase trigger the bronchial hyporesponsiveness after intestinal ischema/reperfusion in rats.
Topics: Animals; Bronchial Hyperreactivity; Enzyme Inhibitors; Glyburide; Guanidines; Interleukin-10; Interl | 2007 |
COX-2-dependent and potentially cardioprotective effects of negative inotropic substances released after ischemia.
Topics: Adenosine Triphosphate; Animals; Calcium Signaling; Cells, Cultured; Cyclooxygenase 2; Cyclooxygenas | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
Transient limb ischemia induces remote preconditioning and remote postconditioning in humans by a K(ATP)-channel dependent mechanism.
Topics: Adult; Aged; Atherosclerosis; Brachial Artery; Endothelium, Vascular; Female; Forearm; Glyburide; He | 2007 |
A protective role of hydrogen sulfide against oxidative stress in rat gastric mucosal epithelium.
Topics: Air Pollutants; Animals; Apoptosis; ATP-Binding Cassette Transporters; Bisbenzimidazole; Cell Death; | 2007 |
Selective cardiac plasma-membrane K(ATP) channel inhibition is defibrillatory and improves survival during acute myocardial ischemia and reperfusion.
Topics: Acute Disease; Anesthesia; Animals; Anti-Arrhythmia Agents; Autonomic Nervous System; Blood Pressure | 2007 |
Hydrogen sulfide contributes to cardioprotection during ischemia-reperfusion injury by opening K ATP channels.
Topics: Animals; Arrhythmias, Cardiac; Cardiotonic Agents; Cells, Cultured; Glyburide; Heart; Hydrogen Sulfi | 2007 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide | 2008 |
Epicardial and endocardial coronary microvascular responses: effects of ischemia-reperfusion.
Topics: Adenosine; Animals; Arginine; Bradykinin; Calcimycin; Coronary Circulation; Endocardium; Endothelium | 1994 |
ATP-sensitive K+ channels are not involved in ischemia-reperfusion lung endothelial injury.
Topics: Adenosine; Adenosine Triphosphate; Animals; Benzopyrans; Capillary Permeability; Cromakalim; Endothe | 1995 |
Cardioprotective effects of a novel calcium antagonist related to the structure of cromakalim.
Topics: Action Potentials; Animals; Benzopyrans; Calcium Channel Blockers; Coronary Circulation; Cromakalim; | 1993 |
Ischemic cardioprotection by ATP-sensitive K+ channels involves high-energy phosphate preservation.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Glyburide; Guanidines; Guinea Pigs; Heart; In Vi | 1993 |
Ischemia reduces CGRP-induced cerebral vascular dilation in piglets.
Topics: Animals; Animals, Newborn; Antioxidants; Arterioles; Calcitonin Gene-Related Peptide; Cerebral Arter | 1996 |
Adenosine inhibition of neutrophil damage during reperfusion does not involve K(ATP)-channel activation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cardiovascular Agents; Cell Adhesion; Creatine Kinase; F | 1997 |
Microvascular permeability with sulfonylureas in normal and diabetic hamsters.
Topics: Animals; Calcium Channel Blockers; Calcium Channels; Capillary Permeability; Cricetinae; Dextrans; D | 1997 |
Acquired resistance of a mammalian cell line to hypoxia-reoxygenation through cotransfection of Kir6.2 and SUR1 clones.
Topics: Animals; Calcium; COS Cells; Genetic Predisposition to Disease; Glyburide; Glycosyltransferases; Hyp | 1998 |
Cardioprotective effect of enantiomers of cicletanine (BN50417, BN50418) in ischaemic/reperfused isolated working rat hearts: interaction with glibenclamide.
Topics: Animals; Antihypertensive Agents; Drug Interactions; Glyburide; Heart; Heart Function Tests; In Vitr | 1999 |
Ischemic preconditioning mediated by activation of KATP channels in rat small intestine.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Cromakalim; Glyburide; Intestine, Small; Ischemic P | 1999 |
Role of an ATP-sensitive potassium channel opener, YM934, in mitochondrial energy production in ischemic/reperfused heart.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Benzoxazines; Creatine Kinase; Cyclic N-Oxi | 1999 |
Opening of K(ATP) channels is mandatory for acquisition of ischemic tolerance by adenosine.
Topics: Adenosine; Adenosine Triphosphate; Animals; Brain; Brain Ischemia; Cell Death; Cells, Cultured; Glyb | 2000 |
Ischemic tolerance conferred to cultured rat neurons by heat shock is not mediated by opening of adenosine triphosphate-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Cells, Cultured; Fetus; Glyburide; Heat-Shock Response; HSP70 Heat- | 2000 |
Protein kinase C and G(i/o) proteins are involved in adenosine- and ischemic preconditioning-mediated renal protection.
Topics: Adenosine; Animals; Bradykinin; Glyburide; GTP-Binding Protein alpha Subunits, Gi-Go; Ischemic Preco | 2001 |
The role of platelet-activating factor (PAF) antagonists and nitric oxide in cardiac actions of PAF. Electrophysiological and morphological study.
Topics: 4-Aminopyridine; Action Potentials; Animals; Azepines; Diterpenes; Electrophysiology; Fibrinolytic A | 2000 |
Effects of cromakalim and glibenclamide on arteriolar and venular diameters and macromolecular leakage in the microcirculation during ischemia/reperfusion.
Topics: Adenosine Triphosphate; Animals; Arterioles; Capillary Permeability; Cheek; Cricetinae; Cromakalim; | 2002 |
Effect of adenosine triphosphate-sensitive potassium channel openers on lung preservation.
Topics: Adenosine Triphosphate; Animals; Disease Models, Animal; Glyburide; Hypertension, Pulmonary; Lung; P | 2002 |