Page last updated: 2024-10-28

glyburide and Infant, Newborn, Diseases

glyburide has been researched along with Infant, Newborn, Diseases in 27 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.

Research Excerpts

ExcerptRelevanceReference
" The relationships between glyburide concentration and the time since the last intake of glyburide and between fetal glyburide concentration and neonatal hypoglycemia were modeled with linear or logistic regressions using fractional polynomials."9.34Transplacental transfer of glyburide in women with gestational diabetes and neonatal hypoglycemia risk. ( Alvarez, JC; Bouchghoul, H; Bouyer, J; Senat, MV; Verstuyft, C, 2020)
"Glyburide is thought to be safe for use during pregnancy for treatment of gestational diabetes mellitus (GDM)."7.81Association of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes. ( Benjamin, DK; Boggess, K; Brookhart, MA; Camelo Castillo, W; Jonsson Funk, M; Stürmer, T, 2015)
" The relationships between glyburide concentration and the time since the last intake of glyburide and between fetal glyburide concentration and neonatal hypoglycemia were modeled with linear or logistic regressions using fractional polynomials."5.34Transplacental transfer of glyburide in women with gestational diabetes and neonatal hypoglycemia risk. ( Alvarez, JC; Bouchghoul, H; Bouyer, J; Senat, MV; Verstuyft, C, 2020)
" Glyburide significantly increased the risk of any neonatal hypoglycemia [risk ratio (RR), 1."4.95Comparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis. ( Chen, L; Chen, Y; Feng, W; Irwin, DM; Liu, Y; Si, X; Song, R, 2017)
"4%) had at least one episode of hypoglycemia, most often in the setting of glyburide."4.12Antenatal maternal hypoglycemia in women with gestational diabetes mellitus and neonatal outcomes. ( Cruz, M; Davitt, C; Harrison, RK; Palatnik, A; Saravanan, V, 2022)
"Glyburide is thought to be safe for use during pregnancy for treatment of gestational diabetes mellitus (GDM)."3.81Association of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes. ( Benjamin, DK; Boggess, K; Brookhart, MA; Camelo Castillo, W; Jonsson Funk, M; Stürmer, T, 2015)
" Median frequencies of hypoglycemia and hyperglycemia were less than 5% of routine blood glucose assays and were similar with both dosage forms."2.90Glibenclamide oral suspension: Suitable and effective in patients with neonatal diabetes. ( Baptiste, A; Beltrand, J; Berdugo, M; Bouazza, N; Boucheron, A; Busiah, K; Djerada, Z; Elie, C; Godot, C; Gozalo, C; Polak, M; Tréluyer, JM, 2019)
" The starting dosage for glyburide was 2."2.87Effect of Glyburide vs Subcutaneous Insulin on Perinatal Complications Among Women With Gestational Diabetes: A Randomized Clinical Trial. ( Affres, H; Beucher, G; Bourcigaux, N; Bouyer, J; Bretelle, F; Castera, V; Cazaubiel, M; Coustols-Valat, M; De Carne, C; Deruelle, P; Desbriere, R; Héron, I; Jacquier, JF; Laboureau, S; Legardeur, H; Letourneau, A; Maillot, F; Mitanchez, D; Morin, M; Rod, A; Rolland, C; Sénat, MV; Sentilhes, L; Simon, E; Verspyck, E, 2018)
"Hypotonia was the symptom that responded best."2.82Sulfonylurea for improving neurological features in neonatal diabetes: A systematic review and meta-analyses. ( Beltrand, J; Berdugo, M; Bernardo, WM; de Gouveia Buff Passone, C; Garcin, L; Giani, E; Kariyawasam, D; Polak, M; Vaivre-Douret, L, 2022)
"A male infant patient developed diabetic ketoacidosis at 2 months-of-age due to the heterozygous ABCC8 gene mutation (p."1.56Neonatal diabetes caused by the heterozygous Pro1198Leu mutation in the ABCC8 gene in a male infant: 6-year clinical course. ( Akamizu, T; Ariyasu, H; Doi, A; Furuta, H; Furuta, M; Iwakura, H; Iwamoto, M; Matsuno, S; Matsutani, N; Miyawaki, M; Morita, S; Nishi, M; Shima, Y; Suzuki, H; Uraki, S, 2020)
" They exhibit marked sensitivity to sulfonylurea therapy with current dosing at 0."1.40Permanent neonatal diabetes mellitus in monozygotic twins achieving low-dose sulfonylurea therapy. ( Ham, JN; Heptulla, R; Hicks, KA; Kushner, JA, 2014)
"Neonates born to women with gestational diabetes managed on glyburide, and were more likely to be macrosomic and to be admitted to the intensive care unit compared to those treated with insulin injections."1.38Treatment of gestational diabetes mellitus: glyburide compared to subcutaneous insulin therapy and associated perinatal outcomes. ( Block-Kurbisch, I; Caughey, AB; Cheng, YW; Chung, JH; Inturrisi, M, 2012)
" On DOL 25, the glyburide dosage was decreased to 0."1.35An oral sulfonylurea in the treatment of transient neonatal diabetes mellitus. ( Bremer, AA; Glaser, NS; Loomba-Albrecht, LA; Styne, DM, 2009)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (7.41)29.6817
2010's17 (62.96)24.3611
2020's8 (29.63)2.80

Authors

AuthorsStudies
Yu, DQ1
Xu, GX1
Teng, XY1
Xu, JW1
Tang, LF1
Feng, C1
Rao, JP1
Jin, M1
Wang, LQ1
Harrison, RK1
Saravanan, V1
Davitt, C1
Cruz, M1
Palatnik, A1
de Gouveia Buff Passone, C1
Giani, E1
Vaivre-Douret, L1
Kariyawasam, D1
Berdugo, M2
Garcin, L1
Beltrand, J2
Bernardo, WM1
Polak, M2
Walton-Betancourth, S1
Ashford, J1
Beardsall, K1
Gooding, N1
Gurnell, EM1
Hendriks, E1
Hysted, H1
Lee, J1
Thankamony, A1
Tseretopoulou, X1
Win, M1
Williams, RM1
Yadav, A3
Kumar, R3
Rawat, A3
Venkatesan, R3
Mancioppi, V1
Pozzi, E1
Zanetta, S1
Missineo, A1
Savastio, S1
Barbetti, F1
Mellone, S1
Giordano, M1
Rabbone, I1
Uraki, S1
Furuta, H1
Miyawaki, M1
Matsutani, N1
Shima, Y1
Iwamoto, M1
Matsuno, S1
Morita, S1
Furuta, M1
Doi, A1
Iwakura, H1
Ariyasu, H1
Nishi, M1
Suzuki, H1
Akamizu, T1
Bouchghoul, H1
Alvarez, JC1
Verstuyft, C1
Bouyer, J2
Senat, MV2
Kylat, RI1
Senguttuvan, R1
Bader, MY1
Song, R1
Chen, L1
Chen, Y1
Si, X1
Liu, Y2
Irwin, DM1
Feng, W1
Li, X1
Xu, A1
Sheng, H1
Ting, TH1
Mao, X1
Huang, X1
Jiang, M1
Cheng, J1
Liu, L1
Neumann, U1
Bührer, C1
Blankenstein, O1
Kühnen, P1
Raile, K1
Yildiz, M1
Akcay, T1
Aydin, B1
Akgun, A1
Dogan, BB1
De Franco, E1
Ellard, S2
Onal, H1
Affres, H1
Letourneau, A1
Coustols-Valat, M1
Cazaubiel, M1
Legardeur, H1
Jacquier, JF1
Bourcigaux, N1
Simon, E1
Rod, A1
Héron, I1
Castera, V1
Sentilhes, L1
Bretelle, F1
Rolland, C1
Morin, M1
Deruelle, P1
De Carne, C1
Maillot, F1
Beucher, G1
Verspyck, E1
Desbriere, R1
Laboureau, S1
Mitanchez, D1
Ioacara, S1
Sava, E1
Barosan, A1
Cojocaru, F1
Gutan, A1
Fica, S1
Baptiste, A1
Busiah, K1
Bouazza, N1
Godot, C1
Boucheron, A1
Djerada, Z1
Gozalo, C1
Tréluyer, JM1
Elie, C1
Yang, W1
Wei, H1
Sang, Y1
Hicks, KA1
Kushner, JA1
Heptulla, R1
Ham, JN1
Verstappen, S1
Mul, D1
Prado-Carro, AM1
Calzada-Hernández, J1
Marín, S1
Cardona-Hernandez, R1
Oriola, J1
Nicolás, M1
Ramon-Krauel, M1
Oka, H1
Suzuki, S1
Furuya, A1
Matsuo, K1
Amamiya, S1
Oshima, M1
Oka, T1
Mukai, T1
Okayama, A1
Araki, A1
Azuma, H1
Tanahashi, Y1
Camelo Castillo, W1
Boggess, K1
Stürmer, T1
Brookhart, MA1
Benjamin, DK1
Jonsson Funk, M1
Hashimoto, Y1
Dateki, S1
Hirose, M1
Satomura, K1
Sawada, H1
Mizuno, H1
Sugihara, S1
Maruyama, K1
Urakami, T1
Sugawara, H1
Shirai, K1
Yorifuji, T1
Loomba-Albrecht, LA1
Glaser, NS1
Styne, DM1
Bremer, AA1
Cheng, YW1
Chung, JH1
Block-Kurbisch, I1
Inturrisi, M1
Caughey, AB1
Siklar, Z1
Okulu, E1
Berberoğlu, M1
Young, E1
Savaş Erdeve, S1
Mungan, IA1
Hacihamdioğlu, B1
Erdeve, O1
Arsan, S1
Oçal, G1
Omori, Y1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Multicenter Randomized Trial of Non-inferiority Between Glyburide and Insulin for the Treatment of Gestational Diabetes[NCT01731431]Phase 3914 participants (Actual)Interventional2012-05-18Completed
Tolerance and Acceptability of Glibentek in Patients With Neonatale Diabetes Secondary to Mutations in K+-ATP Channels[NCT02375828]Phase 310 participants (Actual)Interventional2015-03-20Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for glyburide and Infant, Newborn, Diseases

ArticleYear
Glycemic control and neonatal outcomes in women with gestational diabetes mellitus treated using glyburide, metformin, or insulin: a pairwise and network meta-analysis.
    BMC endocrine disorders, 2021, Oct-12, Volume: 21, Issue:1

    Topics: Adult; Blood Glucose; Diabetes, Gestational; Female; Glyburide; Glycemic Control; Humans; Hypoglycem

2021
Sulfonylurea for improving neurological features in neonatal diabetes: A systematic review and meta-analyses.
    Pediatric diabetes, 2022, Volume: 23, Issue:6

    Topics: Adult; Child; Diabetes Mellitus; Epilepsy; Glyburide; Humans; Infant, Newborn; Infant, Newborn, Dise

2022
Comparison of glyburide and insulin in the management of gestational diabetes: A meta-analysis.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Adult; Birth Weight; Diabetes, Gestational; Disease Management; Female; Glyburide; Humans; Hypoglyce

2017
[Medical management of pregnant women with diabetes].
    Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9

    Topics: Blood Glucose; Body Weight; Congenital Abnormalities; Diabetic Nephropathies; Diabetic Retinopathy;

2002

Trials

3 trials available for glyburide and Infant, Newborn, Diseases

ArticleYear
Transplacental transfer of glyburide in women with gestational diabetes and neonatal hypoglycemia risk.
    PloS one, 2020, Volume: 15, Issue:5

    Topics: Administration, Oral; Adult; Diabetes, Gestational; Dose-Response Relationship, Drug; Female; Fetal

2020
Effect of Glyburide vs Subcutaneous Insulin on Perinatal Complications Among Women With Gestational Diabetes: A Randomized Clinical Trial.
    JAMA, 2018, 05-01, Volume: 319, Issue:17

    Topics: Administration, Oral; Adult; Blood Glucose; Diabetes, Gestational; Female; Fetal Macrosomia; Glyburi

2018
Glibenclamide oral suspension: Suitable and effective in patients with neonatal diabetes.
    Pediatric diabetes, 2019, Volume: 20, Issue:3

    Topics: Administration, Oral; Adolescent; Blood Glucose; Child; Child, Preschool; Diabetes Mellitus; Female;

2019

Other Studies

20 other studies available for glyburide and Infant, Newborn, Diseases

ArticleYear
Antenatal maternal hypoglycemia in women with gestational diabetes mellitus and neonatal outcomes.
    Journal of perinatology : official journal of the California Perinatal Association, 2022, Volume: 42, Issue:8

    Topics: Diabetes, Gestational; Female; Fetal Macrosomia; Glyburide; Humans; Hypoglycemia; Hypoglycemic Agent

2022
Early Postnatal Use of Glibenclamide in Permanent Neonatal Diabetes Secondary to Antenatally Diagnosed KJCN11 Mutation.
    Hormone research in paediatrics, 2022, Volume: 95, Issue:5

    Topics: Blood Glucose; Diabetes Mellitus; Female; Glyburide; Humans; Hypoglycemic Agents; Infant; Infant, Ne

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Neonatal diabetes with a rare LRBA mutation.
    BMJ case reports, 2022, Nov-24, Volume: 15, Issue:11

    Topics: Adaptor Proteins, Signal Transducing; Diabetes Mellitus; Diabetic Ketoacidosis; Glyburide; Humans; I

2022
Case report: Better late than never, but sooner is better: switch from CSII to sulfonylureas in two patients with neonatal diabetes due to KCNJ11 variants.
    Frontiers in endocrinology, 2023, Volume: 14

    Topics: Blood Glucose; Blood Glucose Self-Monitoring; Diabetes Mellitus; Glyburide; Humans; Hypoglycemic Age

2023
Neonatal diabetes caused by the heterozygous Pro1198Leu mutation in the ABCC8 gene in a male infant: 6-year clinical course.
    Journal of diabetes investigation, 2020, Volume: 11, Issue:2

    Topics: Diabetic Ketoacidosis; Glyburide; Glycated Hemoglobin; Humans; Hypoglycemic Agents; Infant, Newborn;

2020
Personalized precision medicine in extreme preterm infants with transient neonatal diabetes mellitus.
    Journal of pediatric endocrinology & metabolism : JPEM, 2017, May-01, Volume: 30, Issue:5

    Topics: Adult; Blood Glucose; Diabetes Mellitus; Female; Genetic Testing; Glyburide; High-Throughput Nucleot

2017
Early transition from insulin to sulfonylureas in neonatal diabetes and follow-up: Experience from China.
    Pediatric diabetes, 2018, Volume: 19, Issue:2

    Topics: China; Chromosome Deletion; Chromosome Disorders; Chromosomes, Human, Pair 1; Cohort Studies; Diabet

2018
Primary sulphonylurea therapy in a newborn with transient neonatal diabetes attributable to a paternal uniparental disomy 6q24 (UPD6).
    Diabetes, obesity & metabolism, 2018, Volume: 20, Issue:2

    Topics: Administration, Oral; Berlin; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Dr

2018
Emergence of insulin resistance following empirical glibenclamide therapy: a case report of neonatal diabetes with a recessive INS gene mutation.
    Journal of pediatric endocrinology & metabolism : JPEM, 2018, Mar-28, Volume: 31, Issue:3

    Topics: Blood Glucose; Consanguinity; Diabetes Mellitus; Glyburide; Homozygote; Humans; Infant, Newborn; Inf

2018
To diet or not to diet in neonatal diabetes responding to sulfonylurea treatment.
    Journal of pediatric endocrinology & metabolism : JPEM, 2018, Sep-25, Volume: 31, Issue:9

    Topics: Combined Modality Therapy; Diabetes Mellitus; Diet, Carbohydrate-Restricted; Female; Glyburide; Huma

2018
KCNJ11 in-frame 15-bp deletion leading to glibenclamide- responsive neonatal diabetes mellitus in a Chinese child.
    Journal of pediatric endocrinology & metabolism : JPEM, 2013, Volume: 26, Issue:5-6

    Topics: Asian People; Diabetes Mellitus; DNA Mutational Analysis; Female; Gene Deletion; Glyburide; Humans;

2013
Permanent neonatal diabetes mellitus in monozygotic twins achieving low-dose sulfonylurea therapy.
    Journal of pediatric endocrinology & metabolism : JPEM, 2014, Volume: 27, Issue:1-2

    Topics: Diabetes Mellitus; Dose-Response Relationship, Drug; Female; Glyburide; Humans; Hypoglycemic Agents;

2014
A 'picturesque' case of transition from subcutaneous to oral treatment in neonatal diabetes.
    BMJ case reports, 2014, May-14, Volume: 2014

    Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus, Type 2; Female; Genetic Testing; Glyburide;

2014
Patient with iDEND syndrome-related mutation.
    Diabetes care, 2014, Volume: 37, Issue:6

    Topics: Diabetes Mellitus; Epilepsy; Female; Glyburide; Humans; Hypoglycemic Agents; Infant, Newborn; Infant

2014
Glycemic control and motor development in a patient with intermediate DEND.
    Pediatrics international : official journal of the Japan Pediatric Society, 2014, Volume: 56, Issue:3

    Topics: Child Development; Diabetes Mellitus; Epilepsy; Glucose; Glyburide; Humans; Infant; Infant, Newborn,

2014
Association of Adverse Pregnancy Outcomes With Glyburide vs Insulin in Women With Gestational Diabetes.
    JAMA pediatrics, 2015, Volume: 169, Issue:5

    Topics: Adult; Cohort Studies; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Agents; Infant

2015
Molecular and clinical features of K
    Pediatric diabetes, 2017, Volume: 18, Issue:7

    Topics: Amino Acid Substitution; Congenital Hyperinsulinism; Diabetes Mellitus; DNA Mutational Analysis; Dru

2017
An oral sulfonylurea in the treatment of transient neonatal diabetes mellitus.
    Clinical therapeutics, 2009, Volume: 31, Issue:4

    Topics: Administration, Oral; Blood Glucose; Diabetes Mellitus; Dose-Response Relationship, Drug; Glyburide;

2009
Treatment of gestational diabetes mellitus: glyburide compared to subcutaneous insulin therapy and associated perinatal outcomes.
    The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 2012, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Cohort Studies; Diabetes, Gestational; Female; Glyburide; Humans; Hypoglycemic Ag

2012
Transient neonatal diabetes with two novel mutations in the KCNJ11 gene and response to sulfonylurea treatment in a preterm infant.
    Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:11-12

    Topics: Diabetes Mellitus; Glyburide; Humans; Hypoglycemic Agents; Infant; Infant, Newborn; Infant, Newborn,

2011