glyburide has been researched along with Hypoxia-Ischemia, Brain in 6 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Hypoxia-Ischemia, Brain: A disorder characterized by a reduction of oxygen in the blood combined with reduced blood flow (ISCHEMIA) to the brain from a localized obstruction of a cerebral artery or from systemic hypoperfusion. Prolonged hypoxia-ischemia is associated with ISCHEMIC ATTACK, TRANSIENT; BRAIN INFARCTION; BRAIN EDEMA; COMA; and other conditions.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoflurane was applied after OGD." | 1.35 | Postconditioning with isoflurane reduced ischemia-induced brain injury in rats. ( Jung, HH; Lee, JJ; Li, L; Zuo, Z, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 2 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, Y | 1 |
| Fathali, N | 1 |
| Lekic, T | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Woo, SK | 1 |
| Kwon, MS | 1 |
| Geng, Z | 1 |
| Chen, Z | 1 |
| Ivanov, A | 1 |
| Bhatta, S | 1 |
| Gerzanich, V | 1 |
| Simard, JM | 1 |
| Ortega, FJ | 1 |
| Gimeno-Bayon, J | 1 |
| Espinosa-Parrilla, JF | 1 |
| Carrasco, JL | 1 |
| Batlle, M | 1 |
| Pugliese, M | 1 |
| Mahy, N | 1 |
| RodrÃguez, MJ | 1 |
| Jiang, K | 1 |
| Zhao, Z | 1 |
| Shui, Q | 1 |
| Xia, Z | 1 |
| Lee, JJ | 1 |
| Li, L | 1 |
| Jung, HH | 1 |
| Zuo, Z | 1 |
| Nakagawa, I | 1 |
| Nakase, H | 1 |
| Aketa, S | 1 |
| Kamada, Y | 1 |
| Yamashita, M | 1 |
| Sakaki, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Inhalatorial Sedation in Patient With SAH Versus Conventional Intravenous Sedation (GAS-SAH)[NCT00830843] | Phase 4 | 13 participants (Actual) | Interventional | 2009-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
6 other studies available for glyburide and Hypoxia-Ischemia, Brain
| Article | Year |
|---|---|
Glibenclamide improves neurological function in neonatal hypoxia-ischemia in rats.
Topics: Animals; Animals, Newborn; ATP-Binding Cassette Transporters; Behavior, Animal; Blood Glucose; Brain | 2009 |
Sequential activation of hypoxia-inducible factor 1 and specificity protein 1 is required for hypoxia-induced transcriptional stimulation of Abcc8.
Topics: Action Potentials; Animals; ATP-Binding Cassette Transporters; Binding Sites; Brain; Calcium Channel | 2012 |
ATP-dependent potassium channel blockade strengthens microglial neuroprotection after hypoxia-ischemia in rats.
Topics: Animals; Cell Line; Dose-Response Relationship, Drug; Glyburide; Hypoxia-Ischemia, Brain; KATP Chann | 2012 |
Electro-acupuncture preconditioning abrogates the elevation of c-Fos and c-Jun expression in neonatal hypoxic-ischemic rat brains induced by glibenclamide, an ATP-sensitive potassium channel blocker.
Topics: Animals; Animals, Newborn; Antihypertensive Agents; Blotting, Western; Brain; Diazoxide; Disease Mod | 2004 |
Postconditioning with isoflurane reduced ischemia-induced brain injury in rats.
Topics: Anesthetics, Inhalation; Animals; Brain; Decanoic Acids; Dose-Response Relationship, Drug; Glyburide | 2008 |
ATP-dependent potassium channel mediates neuroprotection by chemical preconditioning with 3-nitropropionic acid in gerbil hippocampus.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Convulsants; Diazoxide; Excitatory Postsyna | 2002 |