glyburide has been researched along with Hypotension in 18 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine level was significantly higher in G2-SC; reduced in G3-SG and G4-SE." | 5.39 | Glyburide, a K(+)(ATP)channel blocker, improves hypotension and survival in anaphylactic shock induced in Wistar rats sensitized to ovalbumin. ( Abdulle, A; Aburawi, EH; Bellou, A; Bellou, M; Dhanasekaran, S; Kazzam, EE; Nemmar, A, 2013) |
| "We enrolled 30 patients with septic shock requiring invasive hemodynamic monitoring and norepinephrine infusion of 0." | 2.73 | Glibenclamide dose response in patients with septic shock: effects on norepinephrine requirements, cardiopulmonary performance, and global oxygen transport. ( Bachetoni, A; Broeking, K; Ertmer, C; Landoni, G; Lange, M; Morelli, A; Orecchioni, A; Pietropaoli, P; Rocco, M; Traber, DL; Van Aken, H; Westphal, M, 2007) |
| "Histamine level was significantly higher in G2-SC; reduced in G3-SG and G4-SE." | 1.39 | Glyburide, a K(+)(ATP)channel blocker, improves hypotension and survival in anaphylactic shock induced in Wistar rats sensitized to ovalbumin. ( Abdulle, A; Aburawi, EH; Bellou, A; Bellou, M; Dhanasekaran, S; Kazzam, EE; Nemmar, A, 2013) |
| "Dioclein was without effect on contraction of vessels induced by physiological salt solution (PSS) containing 50 mM KCl and the concentration dependence of dioclein's effect on phenylephrine induced contraction was shifted to the right in vessels bathed in PSS containing 25 mM KCl." | 1.31 | Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries. ( Corriu, C; Côrtes, SF; Lemos, VS; Lopes, MJ; Medeiros, IA; Rezende, BA; Teixeira, MM, 2001) |
| "Thus, vasodilation and hypotension in septic shock are, at least in part, due to activation of the K+ATP channel in vascular smooth muscle, and anaerobic metabolism with acidosis is a sufficient stimulus for channel activation." | 1.28 | The ATP-sensitive K+ channel mediates hypotension in endotoxemia and hypoxic lactic acidosis in dog. ( Landry, DW; Oliver, JA, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (61.11) | 18.2507 |
| 2000's | 4 (22.22) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dhanasekaran, S | 1 |
| Nemmar, A | 1 |
| Aburawi, EH | 1 |
| Kazzam, EE | 1 |
| Abdulle, A | 1 |
| Bellou, M | 1 |
| Bellou, A | 1 |
| Cavalcante, HM | 1 |
| Ribeiro, TP | 1 |
| Silva, DF | 1 |
| Nunes, XP | 1 |
| Barbosa-Filho, JM | 1 |
| Diniz, MF | 1 |
| Correia, NA | 1 |
| Braga, VA | 1 |
| Medeiros, IA | 2 |
| Miller, DK | 1 |
| Brinson, AJ | 1 |
| Catalano, G | 1 |
| Catalano, MC | 1 |
| Armstead, WM | 2 |
| Vavilala, MS | 1 |
| Morelli, A | 1 |
| Lange, M | 1 |
| Ertmer, C | 1 |
| Broeking, K | 1 |
| Van Aken, H | 1 |
| Orecchioni, A | 1 |
| Rocco, M | 1 |
| Bachetoni, A | 1 |
| Traber, DL | 1 |
| Landoni, G | 1 |
| Pietropaoli, P | 1 |
| Westphal, M | 1 |
| Vanelli, G | 1 |
| Hussain, SN | 1 |
| Aguggini, G | 1 |
| Chang, HY | 1 |
| Chen, CW | 1 |
| Hsiue, TR | 1 |
| Chen, CR | 1 |
| Schultz, JE | 1 |
| Yao, Z | 1 |
| Cavero, I | 1 |
| Gross, GJ | 1 |
| Miura, K | 1 |
| Kano, S | 1 |
| Nakai, T | 1 |
| Satoh, K | 1 |
| Hoshi, K | 1 |
| Ichihara, K | 1 |
| Toyoda, K | 1 |
| Fujii, K | 1 |
| Ibayashi, S | 1 |
| Kitazono, T | 1 |
| Nagao, T | 1 |
| Fujishima, M | 1 |
| Horikawa, N | 1 |
| Kataha, K | 1 |
| Watanabe, N | 1 |
| Ishii, K | 1 |
| Yanaihara, N | 1 |
| Tanaka, Y | 1 |
| Shigenobu, K | 1 |
| Nakayama, K | 1 |
| Chen, SJ | 1 |
| Wu, CC | 1 |
| Yang, SN | 1 |
| Lin, CI | 1 |
| Yen, MH | 1 |
| Côrtes, SF | 1 |
| Rezende, BA | 1 |
| Corriu, C | 1 |
| Teixeira, MM | 1 |
| Lopes, MJ | 1 |
| Lemos, VS | 1 |
| Andersson, SE | 1 |
| O'Shaughnessy, KM | 1 |
| Newman, CM | 1 |
| Warren, JB | 1 |
| Landry, DW | 1 |
| Oliver, JA | 1 |
| Sugai, T | 1 |
| Kojima, K | 1 |
| Iwakami, N | 1 |
| Suzuki, Y | 1 |
1 trial available for glyburide and Hypotension
| Article | Year |
|---|---|
Glibenclamide dose response in patients with septic shock: effects on norepinephrine requirements, cardiopulmonary performance, and global oxygen transport.
Topics: Adenosine Triphosphate; Aged; Biological Transport; Blood Glucose; Catecholamines; Dose-Response Rel | 2007 |
17 other studies available for glyburide and Hypotension
| Article | Year |
|---|---|
Glyburide, a K(+)(ATP)channel blocker, improves hypotension and survival in anaphylactic shock induced in Wistar rats sensitized to ovalbumin.
Topics: Allergens; Anaphylaxis; Animals; Arterial Pressure; Dinoprost; Dinoprostone; Glyburide; Heart Rate; | 2013 |
Cardiovascular effects elicited by milonine, a new 8,14-dihydromorphinandienone alkaloid.
Topics: Alkaloids; Animals; Aorta; Apamin; Cells, Cultured; Charybdotoxin; Endothelium, Vascular; Glyburide; | 2011 |
Lactic acidosis, hypotension, and sensorineural hearing loss following intentional metformin overdose.
Topics: Acidosis, Lactic; Drug Overdose; Glyburide; Hearing Loss, Sensorineural; Humans; Hypoglycemia; Hypog | 2011 |
Adrenomedullin reduces gender-dependent loss of hypotensive cerebrovasodilation after newborn brain injury through activation of ATP-dependent K channels.
Topics: Adenosine Triphosphate; Adrenomedullin; Animals; Animals, Newborn; Arteries; Brain Injuries; Female; | 2007 |
Glibenclamide, a blocker of ATP-sensitive potassium channels, reverses endotoxin-induced hypotension in pig.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Endotoxins; Escherichia coli; Female; Glyburide; Hy | 1995 |
Role of KATP channels on modulating diaphragmatic microvascular flow during hemorrhagic hypotension.
Topics: Adenosine Triphosphate; Animals; Diaphragm; Diazoxide; Glyburide; Hemorrhage; Hypotension; Laser-Dop | 1997 |
Glibenclamide-induced blockade of ischemic preconditioning is time dependent in intact rat heart.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Glyburide; Heart; Hemodynamics; Hypotension; Ischem | 1997 |
Inhibitory effects of glibenclamide and pertussis toxin on the attenuation of ischemia-induced myocardial acidosis following ischemic preconditioning in dogs.
Topics: Acetylcholine; Acidosis; Adenosine Triphosphate; Animals; Blood Glucose; Blood Pressure; Dogs; Femal | 1997 |
Role of ATP-sensitive potassium channels in brain stem circulation during hypotension.
Topics: Acetylcholine; Animals; Antihypertensive Agents; Arterioles; ATP-Binding Cassette Transporters; Basi | 1997 |
Hypotension dilates pial arteries by KATP and kca channel activation.
Topics: 8-Bromo Cyclic Adenosine Monophosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Arteries; | 1999 |
Glibenclamide-sensitive hypotension produced by helodermin assessed in the rat.
Topics: Animals; Blood Pressure; Glyburide; Heart Rate; Hypotension; Intercellular Signaling Peptides and Pr | 1998 |
Abnormal activation of K(+) channels in aortic smooth muscle of rats with endotoxic shock: electrophysiological and functional evidence.
Topics: Animals; Aorta; Apamin; Benzimidazoles; Charybdotoxin; Drug Interactions; Enzyme Inhibitors; Glyburi | 2000 |
Pharmacological evidence for the activation of potassium channels as the mechanism involved in the hypotensive and vasorelaxant effect of dioclein in rat small resistance arteries.
Topics: 4-Aminopyridine; Analgesics; Animals; Apamin; Barium Compounds; Charybdotoxin; Chlorides; Consciousn | 2001 |
Glibenclamide and L-NG-nitro-arginine methyl ester modulate the ocular and hypotensive effects of calcitonin gene-related peptide.
Topics: Amino Acid Oxidoreductases; Animals; Arginine; Blood Pressure; Calcitonin Gene-Related Peptide; Diaz | 1992 |
Inhibition in the rat of nitric oxide synthesis in vivo does not attenuate the hypotensive action of acetylcholine, ATP or bradykinin.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Arginine; Bradykinin; Endothelium, Vascular; Glyburi | 1992 |
The ATP-sensitive K+ channel mediates hypotension in endotoxemia and hypoxic lactic acidosis in dog.
Topics: Acidosis, Lactic; Adenosine Triphosphate; Animals; Blood Pressure; Dogs; Endotoxins; Glyburide; Hypo | 1992 |
Vasorelaxant and hypotensive effects of tilisolol hydrochloride (N-696) in isolated rat thoracic aorta and pithed rats.
Topics: Adrenergic beta-Antagonists; Animals; Aorta, Thoracic; Benzopyrans; Blood Pressure; Cromakalim; Dose | 1991 |