glyburide has been researched along with Hyperkalemia in 4 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Hyperkalemia: Abnormally high potassium concentration in the blood, most often due to defective renal excretion. It is characterized clinically by electrocardiographic abnormalities (elevated T waves and depressed P waves, and eventually by atrial asystole). In severe cases, weakness and flaccid paralysis may occur. (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "We measured the Na+-Ca2+ exchange outward current with the patch-clamp technique in single rat ventricular myocytes exposed to hyperkalemia and hypothermia in the presence of aprikalim." | 7.71 | Aprikalim reduces the Na+-Ca2+ exchange outward current enhanced by hyperkalemia in rat ventricular myocytes. ( He, GW; Li, HY; Wong, TM; Wu, S, 2002) |
| "During the 7-year study period, 909 elderly patients receiving glyburide were admitted with a diagnosis of hypoglycemia." | 3.72 | Drug-drug interactions among elderly patients hospitalized for drug toxicity. ( Juurlink, DN; Kopp, A; Laupacis, A; Mamdani, M; Redelmeier, DA, 2003) |
| "We measured the Na+-Ca2+ exchange outward current with the patch-clamp technique in single rat ventricular myocytes exposed to hyperkalemia and hypothermia in the presence of aprikalim." | 3.71 | Aprikalim reduces the Na+-Ca2+ exchange outward current enhanced by hyperkalemia in rat ventricular myocytes. ( He, GW; Li, HY; Wong, TM; Wu, S, 2002) |
| "Adenosine has been proposed as an adjunct to hyperkalemic cardioplegic solutions." | 1.29 | Adenosine slows the rate of K(+)-induced membrane depolarization in ventricular cardiomyocytes: possible implication in hyperkalemic cardioplegia. ( Alekseev, AE; Jovanović, A; López, JR; Terzic, A, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Juurlink, DN | 1 |
| Mamdani, M | 1 |
| Kopp, A | 1 |
| Laupacis, A | 1 |
| Redelmeier, DA | 1 |
| Alekseev, AE | 1 |
| Jovanović, A | 1 |
| López, JR | 1 |
| Terzic, A | 1 |
| Tang, T | 1 |
| Dong, C | 1 |
| Duffield, R | 1 |
| Ho, AK | 1 |
| Li, HY | 1 |
| Wu, S | 1 |
| He, GW | 1 |
| Wong, TM | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Transversal, Multicentric Study for Early Detection of Drug Interactions in Older Hospitalized Patients Using on Line Software in Córdoba, Argentina[NCT00850330] | 3,000 participants (Anticipated) | Observational | 2009-06-30 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
4 other studies available for glyburide and Hyperkalemia
| Article | Year |
|---|---|
Drug-drug interactions among elderly patients hospitalized for drug toxicity.
Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Asthmatic Agents; Anti-Infective Agents; Antihy | 2003 |
Adenosine slows the rate of K(+)-induced membrane depolarization in ventricular cardiomyocytes: possible implication in hyperkalemic cardioplegia.
Topics: Adenosine; Animals; Calcium Channels; Cells, Cultured; Glyburide; Guinea Pigs; Heart; Heart Arrest, | 1996 |
Protection of cardiomyocytes by pinacidil during metabolic inhibition and hyperkalemia.
Topics: Adenosine Triphosphate; Animals; Bepridil; Calcium; Calcium Channel Blockers; Cells, Cultured; Chick | 1999 |
Aprikalim reduces the Na+-Ca2+ exchange outward current enhanced by hyperkalemia in rat ventricular myocytes.
Topics: Adenosine Triphosphate; Animals; Calcium; Glyburide; Heart Arrest, Induced; Heart Ventricles; Hyperk | 2002 |