glyburide has been researched along with Hyperinsulinism in 18 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Hyperinsulinism: A syndrome with excessively high INSULIN levels in the BLOOD. It may cause HYPOGLYCEMIA. Etiology of hyperinsulinism varies, including hypersecretion of a beta cell tumor (INSULINOMA); autoantibodies against insulin (INSULIN ANTIBODIES); defective insulin receptor (INSULIN RESISTANCE); or overuse of exogenous insulin or HYPOGLYCEMIC AGENTS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pioglitazone treatment resulted in a significant reduction in fasting levels of PI and SPI compared to those of the controls." | 2.73 | Reduced postprandial proinsulinaemia and 32-33 split proinsulinaemia after a mixed meal in type 2 diabetic patients following sensitization to insulin with pioglitazone. ( Al Majali, K; Bailey, CJ; Betteridge, DJ; Cooper, MB, 2008) |
| "Obesity is often associated with hyperinsulinemia due to insulin resistance." | 1.72 | E4orf1-induced reduction in endogenous insulin level is independent of pancreas endocrine function. ( Akheruzzaman, M; Dhurandhar, NV; Feizy, Z; Hegde, V; Shin, AC; Siddik, MAB, 2022) |
| "Six patients with type 2 diabetes underwent detailed metabolic studies before and after a minimum of 3 months' glibenclamide therapy." | 1.29 | The effects of glibenclamide on glucose homeostasis and lipoprotein metabolism in poorly controlled type 2 diabetes. ( Baynes, C; Elkeles, RS; Henderson, AD; Johnston, DG; Richmond, W, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (16.67) | 18.7374 |
| 1990's | 8 (44.44) | 18.2507 |
| 2000's | 5 (27.78) | 29.6817 |
| 2010's | 1 (5.56) | 24.3611 |
| 2020's | 1 (5.56) | 2.80 |
| Authors | Studies |
|---|---|
| Akheruzzaman, M | 1 |
| Hegde, V | 1 |
| Siddik, MAB | 1 |
| Feizy, Z | 1 |
| Shin, AC | 1 |
| Dhurandhar, NV | 1 |
| da Silva Franco, CC | 1 |
| Previate, C | 1 |
| de Barros Machado, KG | 1 |
| Piovan, S | 1 |
| Miranda, RA | 1 |
| Prates, KV | 1 |
| Moreira, VM | 1 |
| de Oliveira, JC | 1 |
| Barella, LF | 1 |
| Gomes, RM | 1 |
| Francisco, FA | 1 |
| Martins, IP | 1 |
| Pavanello, A | 1 |
| Ribeiro, TA | 1 |
| Tófolo, LP | 1 |
| Malta, A | 1 |
| de Souza, AA | 1 |
| Alves, VS | 1 |
| da Silva Silveira, S | 1 |
| Marçal Natali, MR | 1 |
| Fernando Besson, JC | 1 |
| de Morais, H | 1 |
| de Souza, HM | 1 |
| de Sant Anna, JR | 1 |
| Alves de Castro Prado, MA | 1 |
| de Freitas Mathias, PC | 1 |
| Gupta, RK | 1 |
| Vatamaniuk, MZ | 1 |
| Lee, CS | 1 |
| Flaschen, RC | 1 |
| Fulmer, JT | 1 |
| Matschinsky, FM | 1 |
| Duncan, SA | 1 |
| Kaestner, KH | 1 |
| Patel, NP | 1 |
| Pugh, ME | 1 |
| Goldberg, S | 1 |
| Eiger, G | 1 |
| Cooper, MB | 1 |
| Al Majali, K | 1 |
| Bailey, CJ | 1 |
| Betteridge, DJ | 1 |
| Feldman, S | 1 |
| Camus-Bablon, F | 1 |
| Baynes, C | 1 |
| Elkeles, RS | 1 |
| Henderson, AD | 1 |
| Richmond, W | 1 |
| Johnston, DG | 1 |
| Jones, TW | 1 |
| Boulware, SD | 1 |
| Caprio, S | 1 |
| Merkel, P | 1 |
| Amiel, SA | 1 |
| Pearson, HA | 1 |
| Sherwin, RS | 1 |
| Tamborlane, WV | 1 |
| Thoma, ME | 1 |
| Glauser, J | 1 |
| Genuth, S | 1 |
| Clark, HE | 1 |
| Matthews, DR | 1 |
| Graudins, A | 1 |
| Linden, CH | 1 |
| Ferm, RP | 1 |
| Taschenberger, G | 1 |
| Mougey, A | 1 |
| Shen, S | 1 |
| Lester, LB | 1 |
| LaFranchi, S | 1 |
| Shyng, SL | 1 |
| Hussain, K | 1 |
| Mundy, H | 1 |
| Aynsley-Green, A | 1 |
| Champion, M | 1 |
| Peters, AL | 1 |
| Davidson, MB | 1 |
| Ikeda, T | 1 |
| Fujiyama, K | 1 |
| Hoshino, T | 1 |
| Takeuchi, T | 1 |
| Mashiba, H | 1 |
| Tominaga, M | 1 |
| Margolis, RN | 1 |
| Draznin, B | 1 |
| Sussman, KE | 1 |
| Eckel, RH | 1 |
| Kao, M | 1 |
| Yost, T | 1 |
| Sherman, NA | 1 |
| Schatz, H | 1 |
1 review available for glyburide and Hyperinsulinism
| Article | Year |
|---|---|
[Experience and present status: glibenclamide (Daonil), a reference molecule].
Topics: Blood Glucose; Diabetic Angiopathies; Glyburide; Humans; Hyperinsulinism; Reference Standards | 1994 |
2 trials available for glyburide and Hyperinsulinism
| Article | Year |
|---|---|
Reduced postprandial proinsulinaemia and 32-33 split proinsulinaemia after a mixed meal in type 2 diabetic patients following sensitization to insulin with pioglitazone.
Topics: Adult; Blood Glucose; Diabetes Mellitus, Type 2; Double-Blind Method; Female; Glyburide; Humans; Hyp | 2008 |
The effect of glimepiride on pancreatic beta-cell function under hyperglycaemic clamp and hyperinsulinaemic, euglycaemic clamp conditions in non-insulin-dependent diabetes mellitus.
Topics: Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Glucose Clamp Technique; G | 1996 |
15 other studies available for glyburide and Hyperinsulinism
| Article | Year |
|---|---|
E4orf1-induced reduction in endogenous insulin level is independent of pancreas endocrine function.
Topics: Adenovirus E4 Proteins; Animals; Blood Glucose; Doxycycline; Glucagon; Glucose; Glyburide; Hyperinsu | 2022 |
Chronic Glibenclamide Treatment Attenuates Walker-256 Tumour Growth in Prediabetic Obese Rats.
Topics: Animals; Cachexia; Cell Line, Tumor; Cell Proliferation; Glucose; Glyburide; Hyperinsulinism; Hypogl | 2017 |
The MODY1 gene HNF-4alpha regulates selected genes involved in insulin secretion.
Topics: Animals; Calcium; Diabetes Mellitus, Type 2; DNA-Binding Proteins; Female; Gene Expression Regulatio | 2005 |
Hyperinsulinemic euglycemia therapy for verapamil poisoning: case report.
Topics: Antidotes; Captopril; Critical Care; Drug Combinations; Female; Glyburide; Humans; Hyperinsulinism; | 2007 |
The effects of glibenclamide on glucose homeostasis and lipoprotein metabolism in poorly controlled type 2 diabetes.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Female; Glucose Tolerance Test; Glyburide; Glycerol; | 1993 |
Correction of hyperinsulinemia by glyburide treatment in nondiabetic patients with thalassemia major.
Topics: Adolescent; Adult; beta-Thalassemia; Child; Diabetes Mellitus; Female; Glucose Tolerance Test; Glybu | 1993 |
Persistent hypoglycemia and hyperinsulinemia: caution in using glucagon.
Topics: Adrenergic beta-Antagonists; Alcoholism; Atenolol; Glucagon; Glyburide; Humans; Hyperinsulinism; Hyp | 1996 |
Diagnosis and treatment of sulfonylurea-induced hyperinsulinemic hypoglycemia.
Topics: Gastrointestinal Agents; Glyburide; Humans; Hyperinsulinism; Hypoglycemia; Hypoglycemic Agents; Octr | 1997 |
Identification of a familial hyperinsulinism-causing mutation in the sulfonylurea receptor 1 that prevents normal trafficking and function of KATP channels.
Topics: Amino Acid Motifs; Animals; Antihypertensive Agents; ATP-Binding Cassette Transporters; Base Sequenc | 2002 |
A child presenting with disordered consciousness, hallucinations, screaming episodes and abdominal pain.
Topics: Abdominal Pain; Blood Glucose; Child Abuse; Child, Preschool; Emergency Service, Hospital; Female; F | 2002 |
Reduction of hyperinsulinemia by glyburide--scientific fact or advertising fiction?
Topics: Advertising; Blood Glucose; Diabetes Mellitus; Glyburide; Humans; Hyperinsulinism; Periodicals as To | 1992 |
Effect of long-term administration of insulin and glibenclamide on pancreatic A and B cell function.
Topics: Animals; Arginine; Blood Glucose; Glucagon; Glucose Tolerance Test; Glyburide; Hyperinsulinism; Insu | 1990 |
Hepatic glycogen synthase phosphatase and phosphorylase phosphatase activities are increased in obese (fa/fa) hyperinsulinemic Zucker rats: effects of glyburide administration.
Topics: Animals; Endoplasmic Reticulum; Female; Glucose-6-Phosphate; Glucosephosphates; Glyburide; Glycogen; | 1987 |
Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemia.
Topics: Adipose Tissue; Adult; Biopsy; Calcium; Cytosol; Deoxyglucose; Female; Glyburide; Humans; Hyperinsul | 1988 |
[The pancreatic beta-cell in the field of current diabetology].
Topics: Blood Glucose; Cyclic AMP; Diabetes Mellitus; Glucagon; Glucose Tolerance Test; Glyburide; Growth Ho | 1974 |