Page last updated: 2024-10-28

glyburide and Hypercapnia

glyburide has been researched along with Hypercapnia in 12 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.

Research Excerpts

ExcerptRelevanceReference
"5% O2), to topical adenosine (10[-5] and 10[-4] mol/L) and to arterial hypercapnia (inhalation of 5% and 10% CO2 in air) before and after 10 minutes of global ischemia."3.70Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets. ( Bari, F; Busija, DW; Louis, TM, 1998)
"We assessed the role of extracellular potassium ([K+]e) on the increase in cerebral blood flow (CBF) during hypoxia, and we tested whether it was affected by glibenclamide or ouabain."3.69Role of K+ in regulating hypoxic cerebral blood flow in the rat: effect of glibenclamide and ouabain. ( Paterson, DJ; Reid, JM, 1996)
"Hydrogen sulfide (H2S) is a gaseous signaling molecule that appears to be involved in numerous biological processes, including regulation of blood pressure and vascular tone."1.37Hydrogen sulfide and cerebral microvascular tone in newborn pigs. ( Basuroy, S; Fedinec, AL; Jaggar, JH; Leffler, CW; Parfenova, H; Umstot, ES, 2011)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (41.67)18.2507
2000's3 (25.00)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ma, YC1
Wang, SJ1
Chen, HE1
Huang, LJ1
He, JB1
Wang, Y1
Wang, WT1
Beck, C1
Barthel, F1
Hahn, AM1
Vollmer, C1
Herminghaus, A1
Schäfer, S1
Bauer, I1
Picker, O1
Leffler, CW1
Parfenova, H1
Basuroy, S1
Jaggar, JH1
Umstot, ES1
Fedinec, AL1
Livermore, S1
Piskuric, NA1
Buttigieg, J1
Zhang, M1
Nurse, CA1
Heintz, A1
Koch, T1
Deussen, A1
Reid, JM2
Davies, AG1
Ashcroft, FM1
Paterson, DJ2
Faraci, FM1
Breese, KR1
Heistad, DD1
Bari, F1
Louis, TM1
Busija, DW1
Wang, Q1
Bryan, RM2
Pelligrino, DA1
Golding, EM1
Robertson, CS1
Bayerle-Eder, M1
Wolzt, M1
Polska, E1
Langenberger, H1
Pleiner, J1
Teherani, D1
Rainer, G1
Polak, K1
Eichler, HG1
Schmetterer, L1

Trials

1 trial available for glyburide and Hypercapnia

ArticleYear
Hypercapnia-induced cerebral and ocular vasodilation is not altered by glibenclamide in humans.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2000, Volume: 278, Issue:6

    Topics: Adenosine Triphosphate; Administration, Inhalation; Adult; Blood Glucose; Blood Pressure; Brain; Bra

2000

Other Studies

11 other studies available for glyburide and Hypercapnia

ArticleYear
[Glybenclamide regulate ERK1/2 signal pathway during hypoxia hypercapnia pulmonary vasoconstriction in rats].
    Zhongguo ying yong sheng li xue za zhi = Zhongguo yingyong shenglixue zazhi = Chinese journal of applied physiology, 2014, Volume: 30, Issue:2

    Topics: Animals; Glyburide; Hypercapnia; Hypoxia; In Vitro Techniques; Male; MAP Kinase Signaling System; Pu

2014
The beneficial effects of acute hypercapnia on microcirculatory oxygenation in an animal model of sepsis are independent of K(+)ATP channels.
    Microvascular research, 2015, Volume: 99

    Topics: Adenosine Triphosphate; Animals; Colon; Cytokines; Disease Models, Animal; Glyburide; Hemodynamics;

2015
Hydrogen sulfide and cerebral microvascular tone in newborn pigs.
    American journal of physiology. Heart and circulatory physiology, 2011, Volume: 300, Issue:2

    Topics: Animals; Animals, Newborn; Arterioles; Brain Chemistry; Capillaries; Cerebrovascular Circulation; Cy

2011
Low glucose sensitivity and polymodal chemosensing in neonatal rat adrenomedullary chromaffin cells.
    American journal of physiology. Cell physiology, 2011, Volume: 301, Issue:5

    Topics: Animals; Animals, Newborn; Calcium; Calcium Channel Blockers; Catecholamines; Cell Hypoxia; Cells, C

2011
Intact nitric oxide production is obligatory for the sustained flow response during hypercapnic acidosis in guinea pig heart.
    Cardiovascular research, 2005, Apr-01, Volume: 66, Issue:1

    Topics: Acidosis; Animals; Coronary Circulation; Endothelium, Vascular; Female; Glyburide; Guinea Pigs; Hype

2005
Effect of L-NMMA, cromakalim, and glibenclamide on cerebral blood flow in hypercapnia and hypoxia.
    The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2

    Topics: Animals; Arginine; Arteries; Benzopyrans; Cerebrovascular Circulation; Cromakalim; Glyburide; Hyperc

1995
Cerebral vasodilation during hypercapnia. Role of glibenclamide-sensitive potassium channels and nitric oxide.
    Stroke, 1994, Volume: 25, Issue:8

    Topics: Acetylcholine; Animals; Arginine; Brain; Glyburide; Hypercapnia; Nitric Oxide; Nitroarginine; Nitrop

1994
Role of K+ in regulating hypoxic cerebral blood flow in the rat: effect of glibenclamide and ouabain.
    The American journal of physiology, 1996, Volume: 270, Issue:1 Pt 2

    Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Extracellular Space; Female; G

1996
Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets.
    Stroke, 1998, Volume: 29, Issue:1

    Topics: Adenosine; Adenosine Triphosphate; Administration, Topical; Analysis of Variance; Animals; Arteriole

1998
Calcium-dependent and ATP-sensitive potassium channels and the 'permissive' function of cyclic GMP in hypercapnia-induced pial arteriolar relaxation.
    Brain research, 1998, May-18, Volume: 793, Issue:1-2

    Topics: Adenosine Triphosphate; Animals; Benzimidazoles; Blood Pressure; Calcium; Carbon Dioxide; Cerebral A

1998
L-arginine partially restores the diminished CO2 reactivity after mild controlled cortical impact injury in the adult rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:5

    Topics: Animals; Arginine; Arterioles; Brain; Brain Injuries; Carbon Dioxide; Catalase; Free Radical Scaveng

2000