glyburide has been researched along with Hibernation, Myocardial in 26 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "During reperfusion of ischemic myocardium, a burst of hydroxyl radicals (OH) induces contractile dysfunction ("myocardial stunning"), and OH in the plasma of patients after myocardial infarction predict the development of heart failure." | 3.75 | Endogenous activation of mitochondrial KATP channels protects human failing myocardium from hydroxyl radical-induced stunning. ( Böhm, M; Dabew, ER; Hohl, M; Maack, C; Schäfers, HJ, 2009) |
| "Pretreatment with nicorandil concentration-dependently enhanced the cardioprotective effect of hypothermic high K+ cardioplegia." | 1.29 | The risk of myocardial stunning is decreased concentration-dependently by KATP channel activation with nicorandil before high K+ cardioplegia. ( Dawodu, AA; Iwashiro, K; Monti, F; Puddu, PE; Schiariti, M; Sugimoto, S, 1995) |
| "In both the stunned myocardium model as well as the infarcted myocardium model, the beneficial effects of the potassium channel openers could not be attributed to differences in the traditional determinants of the extent of ischaemia/reperfusion injury; area at risk size, oxygen consumption, or collateral blood flow." | 1.29 | Cardioprotective actions of potassium channel openers. ( Auchampach, JA; Gross, GJ; Maruyama, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (42.31) | 18.2507 |
| 2000's | 15 (57.69) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maack, C | 1 |
| Dabew, ER | 1 |
| Hohl, M | 1 |
| Schäfers, HJ | 1 |
| Böhm, M | 1 |
| del Valle, HF | 5 |
| Lascano, EC | 5 |
| Negroni, JA | 5 |
| McFalls, EO | 1 |
| Kelly, RF | 1 |
| Hu, Q | 1 |
| Mansoor, A | 1 |
| Lee, J | 1 |
| Kuskowski, M | 1 |
| Sikora, J | 1 |
| Ward, HB | 1 |
| Zhang, J | 1 |
| Shigematsu, S | 2 |
| Sato, T | 2 |
| Abe, T | 1 |
| Saikawa, T | 1 |
| Sakata, T | 1 |
| Arita, M | 2 |
| Sugimoto, S | 1 |
| Iwashiro, K | 2 |
| Monti, F | 2 |
| Dawodu, AA | 1 |
| Schiariti, M | 1 |
| Puddu, PE | 2 |
| Offstad, J | 1 |
| Kirkebøen, KA | 1 |
| Ilebekk, A | 1 |
| Downing, SE | 1 |
| Auchampach, JA | 1 |
| Maruyama, M | 1 |
| Gross, GJ | 3 |
| Iwamoto, T | 1 |
| Miura, T | 1 |
| Urabe, K | 1 |
| Itoya, M | 1 |
| Shimamoto, K | 1 |
| Iimura, O | 1 |
| Grover, GJ | 1 |
| Parham, CS | 1 |
| Whigan, DB | 1 |
| Mitroka, JG | 1 |
| Kersten, JR | 2 |
| Lowe, D | 1 |
| Hettrick, DA | 1 |
| Pagel, PS | 2 |
| Warltier, DC | 2 |
| Fukunari, A | 1 |
| Miyai, H | 1 |
| Shinagawa, K | 1 |
| Kawahara, K | 1 |
| Nakajima, T | 1 |
| Elliott, GT | 1 |
| Mei, DA | 1 |
| Taguchi, T | 1 |
| Uchida, W | 1 |
| Takenaka, T | 1 |
| Takeo, S | 1 |
| Picard, S | 1 |
| Criniti, A | 1 |
| La Francesca, S | 1 |
| Ruvolo, G | 1 |
| Papalia, U | 1 |
| Campa, PP | 1 |
| Marino, B | 1 |
| Takano, H | 1 |
| Tang, XL | 1 |
| Bolli, R | 1 |
| Toyoda, Y | 1 |
| Friehs, I | 1 |
| Parker, RA | 1 |
| Levitsky, S | 1 |
| McCully, JD | 1 |
| Narayan, P | 1 |
| Mentzer, RM | 1 |
| Lasley, RD | 1 |
| Gross, ER | 1 |
| Gare, M | 1 |
| Toller, WG | 1 |
| Hara, T | 1 |
| Tomiyasu, S | 1 |
| Sungsam, C | 1 |
| Fukusaki, M | 1 |
| Sumikawa, K | 1 |
| Legtenberg, RJ | 1 |
| Houston, RJ | 1 |
| Oeseburg, B | 1 |
| Smits, P | 1 |
| Crottogini, AJ | 2 |
| Ichikawa, K | 1 |
| Maruyama, K | 1 |
| Murakami, M | 1 |
| Tsuji, A | 1 |
| Yamato, T | 1 |
| Kusama, H | 1 |
| Kojima, M | 1 |
1 review available for glyburide and Hibernation, Myocardial
| Article | Year |
|---|---|
Glibenclamide action on myocardial function and arrhythmia incidence in the healthy and diabetic heart.
Topics: Animals; Arrhythmias, Cardiac; Calcium; Diabetes Complications; Glyburide; Heart; Humans; Hypoglycem | 2007 |
25 other studies available for glyburide and Hibernation, Myocardial
| Article | Year |
|---|---|
Endogenous activation of mitochondrial KATP channels protects human failing myocardium from hydroxyl radical-induced stunning.
Topics: Atrial Function, Left; Cardiomyopathy, Dilated; Diabetes Complications; Female; Gene Expression Regu | 2009 |
Ischemic preconditioning protection against stunning in conscious diabetic sheep: role of glucose, insulin, sarcolemmal and mitochondrial KATP channels.
Topics: Action Potentials; Analysis of Variance; Animals; Decanoic Acids; Diabetes Mellitus, Experimental; D | 2002 |
Ischemic shortening of action potential duration as a result of KATP channel opening attenuates myocardial stunning by reducing calcium influx.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Calcium; Calcium Channel Blockers; Coronary Vess | 2002 |
The energetic state within hibernating myocardium is normal during dobutamine despite inhibition of ATP-dependent potassium channel opening with glibenclamide.
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Dobutamine; Dose-Response Relationship, Drug; D | 2007 |
Pharmacological evidence for the persistent activation of ATP-sensitive K+ channels in early phase of reperfusion and its protective role against myocardial stunning.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Cromakalim; G | 1995 |
The risk of myocardial stunning is decreased concentration-dependently by KATP channel activation with nicorandil before high K+ cardioplegia.
Topics: Adenosine Triphosphate; Animals; Cardioplegic Solutions; Cardiotonic Agents; Combined Modality Thera | 1995 |
ATP gated potassium channels in acute myocardial hibernation and reperfusion.
Topics: Adenosine Triphosphate; Animals; Glyburide; Ion Channel Gating; Myocardial Infarction; Myocardial Re | 1994 |
Cardioprotective actions of potassium channel openers.
Topics: Animals; Benzopyrans; Dihydropyridines; Disease Models, Animal; Dogs; Female; Glyburide; Male; Myoca | 1994 |
Effect of nicorandil on post-ischaemic contractile dysfunction in the heart: roles of its ATP-sensitive K+ channel opening property and nitrate property.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hemodynamics; Infusions, Intravenous; Ion Channel Gating | 1993 |
BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs.
Topics: Animals; Benzopyrans; Cardiotonic Agents; Dogs; Glyburide; Guanidines; Male; Myocardial Contraction; | 1996 |
Glyburide, a KATP channel antagonist, attenuates the cardioprotective effects of isoflurane in stunned myocardium.
Topics: Anesthetics, Inhalation; Animals; Dogs; Female; Glyburide; Heart; Isoflurane; Male; Myocardial Contr | 1996 |
Y-26763 protects the canine heart from a stunning injury through opening of the KATP channels.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Calcium Channel Blockers; Dog | 1997 |
Class I antiarrhythmic drugs alter the severity of myocardial stunning by modulating ATP-sensitive K+ channels in guinea pig ventricular muscles.
Topics: Animals; Anti-Arrhythmia Agents; Glyburide; Guinea Pigs; Heart; Heart Ventricles; Imidazoles; Lidoca | 1998 |
Monophosphoryl lipid A attenuates myocardial stunning in dogs: role of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Blood Gas Analysis; Blood Pressure; Coronary Circulation; Decanoic | 1998 |
Cardioprotective effects of YM934, an ATP-sensitive potassium channel opener, on stunned myocardium in anesthetized dogs.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Benzoxazines; Coronary Circulation; Cyclic N-Oxides; Do | 1999 |
Adenosine triphosphate-dependent potassium channel modulation and cardioplegia-induced protection of human atrial muscle in an in vitro model of myocardial stunning.
Topics: Adenosine Triphosphate; Adult; Aged; Atrial Function, Right; Benzopyrans; Bicarbonates; Calcium Chlo | 2000 |
Differential role of K(ATP) channels in late preconditioning against myocardial stunning and infarction in rabbits.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Glyburide; Heart; Hemodynamics; Hydroxy | 2000 |
Differential role of sarcolemmal and mitochondrial K(ATP) channels in adenosine-enhanced ischemic preconditioning.
Topics: Adenosine; Animals; Anti-Arrhythmia Agents; Calcium; Decanoic Acids; Glyburide; Hydroxy Acids; Hypog | 2000 |
Adenosine A1 receptor activation reduces reactive oxygen species and attenuates stunning in ventricular myocytes.
Topics: Adenosine; Aniline Compounds; Animals; Calcium; Decanoic Acids; Drug Synergism; Fluoresceins; Fluore | 2001 |
Ethanol enhances the functional recovery of stunned myocardium independent of K(ATP) channels in dogs.
Topics: Adenosine Triphosphate; Animals; Dogs; Ethanol; Glyburide; Myocardial Stunning; Potassium Channels | 2001 |
Sevoflurane protects stunned myocardium through activation of mitochondrial ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Coronary Circulation; Decanoic Acids; Dogs | 2001 |
Effects of sulfonylurea derivatives on ischemia-induced loss of function in the isolated rat heart.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Circulation; Dose-Response Relationship, Drug; Glyburide; | 2001 |
Glibenclamide effects on reperfusion-induced malignant arrhythmias and left ventricular mechanical recovery from stunning in conscious sheep.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Glyburide; Hemodynamics; H | 2001 |
Absence of exacerbation of myocardial stunning in anesthetized dogs treated with KAD-1229, a novel hypoglycemic agent.
Topics: Animals; ATP-Binding Cassette Transporters; Binding, Competitive; Coronary Circulation; Dogs; Electr | 2001 |
ATP-sensitive potassium channels do not have a main role in mediating late preconditioning protection against arrhythmias and stunning in conscious sheep.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Co | 2002 |