glyburide has been researched along with Hemorrhagic Shock in 12 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study was designed to evaluate the effects of glibenclamide, a K(+)(ATP) channel blocker, on renal function and histology in rats in a state of hemorrhagic shock under sevoflurane anesthesia." | 3.74 | Glibenclamide effects on renal function and histology after acute hemorrhage in rats under sevoflurane anesthesia. ( Braz, JR; Castiglia, YM; Diego, LA; Marques, CD; Vianna, PT; Viero, RM, 2007) |
| " Interspecies dosing differences versus prior studies may play an important role in these findings." | 1.48 | Glibenclamide Produces Region-Dependent Effects on Cerebral Edema in a Combined Injury Model of Traumatic Brain Injury and Hemorrhagic Shock in Mice. ( Hoshitsuki, K; Jackson, TC; Janesko-Feldman, KL; Jha, RM; Kochanek, PM; Minnigh, MB; Molyneaux, BJ; Park, SY; Poloyac, S; Vagni, VA; Wallisch, JS, 2018) |
| "Cardiac dysfunction during hemorrhagic shock (HS) is associated with myocardial ischemia, during which adenosine triphosphate (ATP)-sensitive potassium (K(ATP)) channels can be activated." | 1.35 | Adenosine triphosphate-sensitive potassium channels prevent extension of myocardial ischemia to subepicardium during hemorrhagic shock. ( Adachi, T; Aikawa, N; Hori, S; Inoue, S; Miyazaki, K; Mori, H; Nakagawa, M; Nakazawa, H; Ogawa, S; Suzuki, M, 2008) |
| "Rats were subjected to hemorrhagic shock (HS) for 2 hours." | 1.31 | The role of membrane potential and calcium kinetic changes in the pathogenesis of vascular hyporeactivity during severe shock. ( Jin, C; Liu, J; Zhao, K, 2000) |
| "Hemorrhagic shock is associated with early vasomotor paralysis as well as with early derangements in the intracellular metabolic status." | 1.29 | Inhibition of ATP-activated potassium channels exerts pressor effects and improves survival in a rat model of severe hemorrhagic shock. ( Salzman, AL; Szabó, C, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (25.00) | 18.2507 |
| 2000's | 7 (58.33) | 29.6817 |
| 2010's | 2 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jha, RM | 1 |
| Molyneaux, BJ | 1 |
| Jackson, TC | 1 |
| Wallisch, JS | 1 |
| Park, SY | 1 |
| Poloyac, S | 1 |
| Vagni, VA | 1 |
| Janesko-Feldman, KL | 1 |
| Hoshitsuki, K | 1 |
| Minnigh, MB | 1 |
| Kochanek, PM | 1 |
| Marques, CD | 2 |
| Diego, LA | 2 |
| Marcondes-Machado, J | 1 |
| Amorim, RL | 1 |
| Carvalho, LR | 1 |
| Módolo, NS | 1 |
| Braz, LG | 1 |
| Castiglia, YM | 2 |
| Zhao, KS | 2 |
| Huang, X | 2 |
| Liu, J | 3 |
| Huang, Q | 2 |
| Jin, C | 3 |
| Jiang, Y | 1 |
| Jin, J | 1 |
| Zhao, G | 1 |
| Maybauer, DM | 1 |
| Salsbury, JR | 1 |
| Westphal, M | 1 |
| Maybauer, MO | 1 |
| Salzman, AL | 3 |
| Szabó, C | 3 |
| Westphal-Varghese, BB | 1 |
| Traber, LD | 1 |
| Traber, DL | 1 |
| Mok, YY | 1 |
| Atan, MS | 1 |
| Yoke Ping, C | 1 |
| Zhong Jing, W | 1 |
| Bhatia, M | 1 |
| Moochhala, S | 1 |
| Moore, PK | 1 |
| Vianna, PT | 1 |
| Viero, RM | 1 |
| Braz, JR | 1 |
| Nakagawa, M | 1 |
| Hori, S | 1 |
| Adachi, T | 1 |
| Miyazaki, K | 1 |
| Inoue, S | 1 |
| Suzuki, M | 1 |
| Mori, H | 1 |
| Nakazawa, H | 1 |
| Aikawa, N | 1 |
| Ogawa, S | 1 |
| Vromen, A | 1 |
| Denenberg, A | 1 |
| Pieber, D | 1 |
| Horina, G | 1 |
| Sandner-Kiesling, A | 1 |
| Pieber, TR | 1 |
| Heinemann, A | 1 |
| Yang, GY | 1 |
| Zhao, K | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hydrogen Sulfide as Prognostic Factor[NCT01088490] | 50 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
12 other studies available for glyburide and Hemorrhagic Shock
| Article | Year |
|---|---|
Glibenclamide Produces Region-Dependent Effects on Cerebral Edema in a Combined Injury Model of Traumatic Brain Injury and Hemorrhagic Shock in Mice.
Topics: Animals; Blood Glucose; Brain Edema; Brain Injuries, Traumatic; Disease Models, Animal; Glyburide; H | 2018 |
Serum concentrations and renal expressions of IL-1 and TNF-a early after hemorrhage in rats under the effect of glibenclamide.
Topics: Anesthetics, Inhalation; Animals; Body Weight; Glyburide; Hypoglycemic Agents; Interleukin-1; KATP C | 2016 |
New approach to treatment of shock--restitution of vasoreactivity.
Topics: Animals; Blood Pressure; Dimethyl Sulfoxide; Disease Models, Animal; Dopamine; Glyburide; Hemodynami | 2002 |
The ATP-sensitive potassium-channel inhibitor glibenclamide improves outcome in an ovine model of hemorrhagic shock.
Topics: Animals; Blood Pressure; Female; Glyburide; Hemodynamics; Hydrogen-Ion Concentration; Ileum; Kidney; | 2004 |
Role of hydrogen sulphide in haemorrhagic shock in the rat: protective effect of inhibitors of hydrogen sulphide biosynthesis.
Topics: Alanine; Alkynes; Animals; ATP-Binding Cassette Transporters; Blood Pressure; Cystathionine gamma-Ly | 2004 |
Glibenclamide effects on renal function and histology after acute hemorrhage in rats under sevoflurane anesthesia.
Topics: Anesthetics, Inhalation; Animals; Genotype; Glyburide; Hypoglycemic Agents; Kidney; Kidney Function | 2007 |
Adenosine triphosphate-sensitive potassium channels prevent extension of myocardial ischemia to subepicardium during hemorrhagic shock.
Topics: Animals; Coronary Circulation; Disease Models, Animal; Dogs; Glyburide; KATP Channels; Myocardial Is | 2008 |
Inhibition of ATP-activated potassium channels exerts pressor effects and improves survival in a rat model of severe hemorrhagic shock.
Topics: Animals; ATP-Binding Cassette Transporters; Blood Pressure; Disease Models, Animal; Glyburide; Heart | 1996 |
K(ATP)-channel inhibition improves hemodynamics and cellular energetics in hemorrhagic shock.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Glyburide; Hemodynamics; Isotonic Solutions; Mal | 1997 |
Pressor and mesenteric arterial hyporesponsiveness to angiotensin II is an early event in haemorrhagic hypotension in anaesthetised rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arginine Vasopressin; Benzimidazoles; Ben | 1999 |
Peroxynitrite leads to arteriolar smooth muscle cell membrane hyperpolarization and low vasoreactivity in severe shock.
Topics: 1,2-Dihydroxybenzene-3,5-Disulfonic Acid Disodium Salt; Animals; Arginine; Arterioles; Charybdotoxin | 2000 |
The role of membrane potential and calcium kinetic changes in the pathogenesis of vascular hyporeactivity during severe shock.
Topics: Animals; Calcium; Glyburide; Membrane Potentials; Muscle, Smooth, Vascular; Norepinephrine; Potassiu | 2000 |