glyburide has been researched along with Heart Failure in 16 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Heart Failure: A heterogeneous condition in which the heart is unable to pump out sufficient blood to meet the metabolic need of the body. Heart failure can be caused by structural defects, functional abnormalities (VENTRICULAR DYSFUNCTION), or a sudden overload beyond its capacity. Chronic heart failure is more common than acute heart failure which results from sudden insult to cardiac function, such as MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 5.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| "During reperfusion of ischemic myocardium, a burst of hydroxyl radicals (OH) induces contractile dysfunction ("myocardial stunning"), and OH in the plasma of patients after myocardial infarction predict the development of heart failure." | 3.75 | Endogenous activation of mitochondrial KATP channels protects human failing myocardium from hydroxyl radical-induced stunning. ( Böhm, M; Dabew, ER; Hohl, M; Maack, C; Schäfers, HJ, 2009) |
| "Glyburide delays release of ANP in acute heart failure resulting in impaired natriuresis." | 3.70 | The modulating actions of sulfonylurea on atrial natriuretic peptide release in experimental acute heart failure. ( Burnett, JC; Chen, HH; Oh, KY; Terzic, A, 2000) |
| "To examine the status of ATP-sensitive K+ (K+ATP) channels and 1,4-dihydropyridine-sensitive Ca2+ (Ca2+DHP) channels during experimental cardiac failure, we have measured the radioligand binding properties of [3H]glyburide and [3H]PN 200 110, respectively, in tissue homogenates from the rat cardiac left ventricle, right ventricle, and brain 4 wk after myocardial infarction induced by left coronary artery ligation." | 3.68 | Regulation of K+ and Ca2+ channels in experimental cardiac failure. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Rutledge, A; Triggle, DJ, 1991) |
| "Continuous nitroglycerin (NTG) administration causes pharmacologic tolerance in humans and animals, whereas intermittent dosing is capable of avoiding or reducing tolerance development." | 1.29 | Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels. ( Bauer, JA; Fung, HL; Gopalakrishnan, M; Kwon, YW; Triggle, DJ; Zheng, W, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (12.50) | 18.7374 |
| 1990's | 4 (25.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 4 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abo-Salem, OM | 1 |
| Harisa, GI | 1 |
| Ali, TM | 1 |
| El-Sayed, el-SM | 1 |
| Abou-Elnour, FM | 1 |
| Jameel, MN | 1 |
| Xiong, Q | 1 |
| Mansoor, A | 1 |
| Bache, RJ | 2 |
| Zhang, J | 1 |
| Wang, S | 1 |
| Long, CL | 1 |
| Chen, J | 1 |
| Cui, WY | 1 |
| Zhang, YF | 1 |
| Zhang, H | 1 |
| Wang, H | 1 |
| Maack, C | 1 |
| Dabew, ER | 1 |
| Hohl, M | 1 |
| Schäfers, HJ | 1 |
| Böhm, M | 1 |
| Andersson, C | 1 |
| Gislason, GH | 1 |
| Jørgensen, CH | 1 |
| Hansen, PR | 1 |
| Vaag, A | 1 |
| Sørensen, R | 1 |
| Mérie, C | 1 |
| Olesen, JB | 1 |
| Weeke, P | 1 |
| Schmiegelow, M | 1 |
| Norgaard, ML | 1 |
| Køber, L | 1 |
| Torp-Pedersen, C | 1 |
| Aronson, D | 1 |
| Mittleman, MA | 1 |
| Burger, AJ | 1 |
| Nesto, RW | 1 |
| Bell, D | 1 |
| Bonow, RO | 1 |
| Fonseca, V | 1 |
| Grundy, SM | 1 |
| Horton, ES | 1 |
| Le Winter, M | 1 |
| Porte, D | 1 |
| Semenkovich, CF | 1 |
| Smith, S | 1 |
| Young, LH | 1 |
| Kahn, R | 1 |
| Traverse, JH | 1 |
| Chen, Y | 1 |
| Hou, M | 1 |
| Li, Y | 1 |
| Lysy, Y | 1 |
| Globus, M | 1 |
| Chowers, I | 1 |
| Bauer, JA | 2 |
| Fung, HL | 2 |
| Zheng, W | 1 |
| Kwon, YW | 2 |
| Gopalakrishnan, M | 2 |
| Triggle, DJ | 2 |
| Koumi, SI | 1 |
| Martin, RL | 1 |
| Sato, R | 1 |
| Chen, HH | 1 |
| Oh, KY | 1 |
| Terzic, A | 1 |
| Burnett, JC | 1 |
| Yamamoto, M | 1 |
| Egashira, K | 1 |
| Arimura, K | 1 |
| Tada, H | 1 |
| Shimokawa, H | 1 |
| Takeshita, A | 1 |
| Rutledge, A | 1 |
| George, S | 1 |
| McBurney, A | 1 |
| Cole, A | 1 |
| Ravina, A | 1 |
| Kain, T | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Influence of Rosiglitazone on the Diuretic Effect of Furosemide and Amiloride. A Double-blind Placebo Controlled Cross Over Study.[NCT00285805] | 13 participants (Actual) | Interventional | 2006-02-28 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for glyburide and Heart Failure
| Article | Year |
|---|---|
Thiazolidinedione use, fluid retention, and congestive heart failure: a consensus statement from the American Heart Association and American Diabetes Association. October 7, 2003.
Topics: Blood Volume; Clinical Trials as Topic; Comorbidity; Contraindications; Diabetes Mellitus, Type 2; D | 2003 |
1 trial available for glyburide and Heart Failure
| Article | Year |
|---|---|
Effects of sulfonylurea hypoglycemic agents and adenosine triphosphate dependent potassium channel antagonists on ventricular arrhythmias in patients with decompensated heart failure.
Topics: Aged; Analysis of Variance; Anti-Arrhythmia Agents; Chi-Square Distribution; Diabetes Complications; | 2003 |
14 other studies available for glyburide and Heart Failure
| Article | Year |
|---|---|
Curcumin ameliorates streptozotocin-induced heart injury in rats.
Topics: Animals; Antioxidants; Blood Glucose; Curcumin; Diabetes Mellitus, Experimental; Glutathione; Glybur | 2014 |
ATP sensitive K(+) channels are critical for maintaining myocardial perfusion and high energy phosphates in the failing heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Disease Models, Animal; Dogs; Glyburide; Hear | 2016 |
Pharmacological evidence: a new therapeutic approach to the treatment of chronic heart failure through SUR2B/Kir6.1 channel in endothelial cells.
Topics: Allyl Compounds; Animals; Dose-Response Relationship, Drug; Endothelial Cells; Glyburide; Heart Fail | 2017 |
Endogenous activation of mitochondrial KATP channels protects human failing myocardium from hydroxyl radical-induced stunning.
Topics: Atrial Function, Left; Cardiomyopathy, Dilated; Diabetes Complications; Female; Gene Expression Regu | 2009 |
Comparable long-term mortality risk associated with individual sulfonylureas in diabetes patients with heart failure.
Topics: Aged; Aged, 80 and over; Diabetes Mellitus; Female; Glipizide; Glyburide; Heart Failure; Humans; Hyp | 2011 |
Effect of K+ATP channel and adenosine receptor blockade during rest and exercise in congestive heart failure.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Cardiac Pacing, Artifi | 2007 |
Control of hypoglycemia by the Biostator.
Topics: Aged; Computers; Diabetes Mellitus, Type 2; Female; Glucose; Glyburide; Heart Failure; Humans; Hypog | 1984 |
Continuous versus intermittent nitroglycerin administration in experimental heart failure: vascular relaxation and radioligand binding to adrenoceptors and ion channels.
Topics: Administration, Cutaneous; Animals; Aorta, Thoracic; Binding Sites; Drug Tolerance; Glyburide; Heart | 1993 |
Alterations in ATP-sensitive potassium channel sensitivity to ATP in failing human hearts.
Topics: Action Potentials; Adenosine Triphosphate; Adult; Cells, Cultured; Cyanides; Deoxyglucose; Glyburide | 1997 |
The modulating actions of sulfonylurea on atrial natriuretic peptide release in experimental acute heart failure.
Topics: Animals; Atrial Natriuretic Factor; Dogs; Glyburide; Heart Atria; Heart Failure; Hemodynamics; Hypog | 2000 |
Coronary vascular K+ATP channels contribute to the maintenance of myocardial perfusion in dogs with pacing-induced heart failure.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Dose-Response Relatio | 2000 |
Regulation of K+ and Ca2+ channels in experimental cardiac failure.
Topics: Animals; Body Weight; Brain; Calcium Channel Blockers; Calcium Channels; Coronary Vessels; Dihydropy | 1991 |
Possible protein binding displacement interaction between glibenclamide and metolazone.
Topics: Aged; Binding, Competitive; Blood Proteins; Dialysis; Diuretics; Glyburide; Heart Failure; Humans; H | 1990 |
[Chlorpropamide, thiazides and congestive heart failure].
Topics: Aged; Chlorpropamide; Diabetes Mellitus; Diuresis; Diuretics; Glyburide; Heart Failure; Humans; Hydr | 1974 |