glyburide has been researched along with Glycosuria in 41 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Glycosuria: The appearance of an abnormally large amount of GLUCOSE in the urine, such as more than 500 mg/day in adults. It can be due to HYPERGLYCEMIA or genetic defects in renal reabsorption (RENAL GLYCOSURIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of glibenclamide and gliquidone on fasting blood glucose, 24-hour urinary glucose excretion, HbA1 concentrations and on the blood glucose and plasma insulin responses to an oral glucose load were investigated in 11 patients with non-insulin-dependent diabetes mellitus." | 9.05 | Glibenclamide and gliquidone in the treatment of non-insulin-dependent diabetes mellitus. ( Groop, L; Nikkilä, K, 1982) |
| "The effect of glibenclamide and gliquidone on fasting blood glucose, 24-hour urinary glucose excretion, HbA1 concentrations and on the blood glucose and plasma insulin responses to an oral glucose load were investigated in 11 patients with non-insulin-dependent diabetes mellitus." | 5.05 | Glibenclamide and gliquidone in the treatment of non-insulin-dependent diabetes mellitus. ( Groop, L; Nikkilä, K, 1982) |
| "Forty patients with diabetes mellitus and rheumatic disorders (rheumatoid arthritis, osteoarthritis, soft-tissue rheumatism) were included in a double-blind trial with the purpose of investigating whether the concomitant administration of tolmetin and glibenclamide leads to an interaction." | 5.04 | Clinical studies of the interaction between tolmetin and glibenclamide. ( Chlud, K; Kaik, B, 1977) |
| " The body weight changes, blood and urine glucose level changes were monitored with changes on the pancreas weight, and after sacrifice, the histopathological changes of pancreas and the changes of insulin- and glucagon-producing cells were also observed by immunohistochemistry." | 3.73 | Anti-diabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study. ( Choi, HS; Choi, HY; Kang, SM; Kim, JD; Ku, SK; Seo, BI, 2006) |
| "Alterations in plasma branched-chain amino acids (valine, isoleucine and leucine) and alanine have been described in patients with insulin-dependent diabetes mellitus who have poor metabolic control." | 3.66 | Branched-chain amino acids and alanine as indices of the metabolic control in type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetic patients. ( Angiolini, A; Ciavarella, A; Forlani, G; Marchesini, G; Pisi, E; Vannini, P; Zoli, M, 1982) |
| " Therefore, it is apparent that the addition of glibenclamide to insulin reduces daily insulin dosage and renders a greater uniformity to diurnal blood glucose control, most probably secondary to enhancement of insulin sensitivity." | 2.68 | More uniform diurnal blood glucose control and a reduction in daily insulin dosage on addition of glibenclamide to insulin in type 1 diabetes mellitus: role of enhanced insulin sensitivity. ( Birkenholz, M; Kabadi, M; Kabadi, UM; McCoy, S, 1995) |
| "The test drugs were dosed as follows: 100 mg acarbose (A) three times a day, 1 placebo tablet three times a day, 3." | 2.67 | Efficacy of 24-week monotherapy with acarbose, glibenclamide, or placebo in NIDDM patients. The Essen Study. ( Hoffmann, J; Spengler, M, 1994) |
| "Present treatment of type II diabetes mellitus often fails to normalize post-prandial glucoses." | 2.66 | Combined glyburide and insulin therapy in type II diabetes. ( Abraira, C; Lawrence, AM; Reich, A, 1987) |
| " To determine an optimal glyburide dosage schedule, the effects of glyburide once (every morning) or twice daily and chlorpropamide once daily (every morning) were compared in 18 men with non-insulin-dependent diabetes mellitus in a randomized, double-blind fashion." | 2.66 | Once-daily use of glyburide. ( Fajardo, F; Ginier, P; Levin, SR; Madan, S, 1985) |
| " Post-dose glipizide concentrations were three times higher than those of glibenclamide, due to the incomplete bioavailability of the latter." | 2.66 | Pharmacokinetics and metabolic effects of glibenclamide and glipizide in type 2 diabetics. ( Fyhrqvist, F; Groop, L; Groop, PH; Melander, A; Tolppanen, EM; Tötterman, KJ; Wåhlin-Boll, E, 1985) |
| "The R6/2 transgenic mouse model of Huntington's disease (HD) develops a progressive neurological phenotype that involves severe motor and cognitive dysfunctions." | 1.33 | Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents. ( Hunt, MJ; Morton, AJ, 2005) |
| "Sixteen patients with type 2 diabetes poorly controlled by glibenclamide (7." | 1.29 | Effect of acarbose on blood glucose profiles and plasma 1,5-anhydro-d-glucitol in type 2 diabetes poorly controlled by sulfonylurea therapy. ( Fukasawa, H; Hotta, N; Kakuta, H; Koh, N; Naruse, K; Sakakibara, F; Takeuchi, N; Yamada, K; Yamada, T, 1996) |
| " Due to the high frequency of side effects it does not seem to be worthwhile to further investigate the therapeutic effect of MPC in a larger number of patients with different dosage regimens." | 1.25 | [Effect of methylpyrazole-carboxylic acid on carbohydrate and lipid metabolisms in patients with diabetes mellitus]. ( Hassalacher, Ch; Lang, PD; Vollmar, J; Wahl, P, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (70.73) | 18.7374 |
| 1990's | 7 (17.07) | 18.2507 |
| 2000's | 4 (9.76) | 29.6817 |
| 2010's | 1 (2.44) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Udayakumar, R | 1 |
| Kasthurirengan, S | 1 |
| Mariashibu, TS | 1 |
| Rajesh, M | 1 |
| Anbazhagan, VR | 1 |
| Kim, SC | 1 |
| Ganapathi, A | 1 |
| Choi, CW | 1 |
| Gupta, R | 1 |
| Sharma, AK | 1 |
| Dobhal, MP | 1 |
| Sharma, MC | 1 |
| Gupta, RS | 1 |
| Hunt, MJ | 1 |
| Morton, AJ | 1 |
| Kim, JD | 1 |
| Kang, SM | 1 |
| Seo, BI | 1 |
| Choi, HY | 1 |
| Choi, HS | 1 |
| Ku, SK | 1 |
| Ramesh, B | 1 |
| Pugalendi, KV | 1 |
| Sachse, G | 1 |
| Mäser, E | 1 |
| Federlin, K | 1 |
| Groop, L | 5 |
| Harno, K | 2 |
| Tolppanen, EM | 3 |
| Annamala, PT | 1 |
| Augusti, KT | 2 |
| Nikkilä, K | 1 |
| Vannini, P | 1 |
| Marchesini, G | 1 |
| Forlani, G | 1 |
| Angiolini, A | 1 |
| Ciavarella, A | 1 |
| Zoli, M | 1 |
| Pisi, E | 1 |
| Konstantopoulos, K | 1 |
| Adamides, S | 1 |
| Hoffmann, J | 1 |
| Spengler, M | 1 |
| Sheela, CG | 1 |
| Kabadi, UM | 1 |
| McCoy, S | 1 |
| Birkenholz, M | 1 |
| Kabadi, M | 1 |
| Hotta, N | 1 |
| Koh, N | 1 |
| Sakakibara, F | 1 |
| Naruse, K | 1 |
| Yamada, T | 1 |
| Takeuchi, N | 1 |
| Yamada, K | 1 |
| Fukasawa, H | 1 |
| Kakuta, H | 1 |
| Knick, B | 1 |
| Thomas, L | 1 |
| Vollmar, J | 2 |
| Bauer, G | 1 |
| Mogensen, EF | 1 |
| Worm, J | 1 |
| Mikkelsen, BO | 1 |
| Chlud, K | 1 |
| Kaik, B | 1 |
| Lang, PD | 1 |
| Wahl, P | 1 |
| Hassalacher, Ch | 1 |
| Wildenhoff, KE | 1 |
| Boyd, K | 1 |
| Rogers, C | 1 |
| Boreham, C | 1 |
| Andrews, WJ | 1 |
| Hadden, DR | 1 |
| Velussi, M | 1 |
| Cernigoi, AM | 1 |
| Viezzoli, L | 1 |
| Caffau, C | 1 |
| Reich, A | 1 |
| Abraira, C | 1 |
| Lawrence, AM | 1 |
| Welle, S | 1 |
| Nair, KS | 1 |
| Lockwood, D | 1 |
| Salo, S | 1 |
| Balabolkin, MI | 1 |
| Nedosugova, LV | 1 |
| Nikkilä, EA | 1 |
| Pelkonen, R | 1 |
| Ginier, P | 1 |
| Madan, S | 1 |
| Fajardo, F | 1 |
| Levin, SR | 1 |
| Wåhlin-Boll, E | 1 |
| Groop, PH | 1 |
| Tötterman, KJ | 1 |
| Melander, A | 1 |
| Fyhrqvist, F | 1 |
| Fähndrich, W | 1 |
| Liebermeister, H | 1 |
| Schmitt, H | 1 |
| Daweke, H | 1 |
| De Leeuw, I | 1 |
| De Baere, H | 1 |
| Decraene, P | 1 |
| Lemmens, P | 1 |
| Verhaegen, H | 1 |
| Sweet, RD | 1 |
| Tattersall, RB | 1 |
| Beringer, A | 1 |
| Happ, J | 1 |
| Beyer, J | 2 |
| Nest, E | 1 |
| Fröhlich, A | 1 |
| Althoff, PH | 1 |
| Schöffling, K | 2 |
| Parodi, FA | 1 |
| Zöllner, N | 1 |
| Dörfler, H | 1 |
| Wolfram, G | 1 |
| Blohmé, G | 1 |
| Mehnert, H | 1 |
| Ewald, W | 1 |
| Haupt, E | 1 |
| Wicklmayr, M | 1 |
| Nemeth, N | 1 |
| Burns, FH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot, Open-label Study to Evaluate the Effects of a Prostate Health Formulation on Scores Attained From the International Prostate Symptom Score (I-PSS) Questionnaire Among Overall Healthy Male Participants Who Report Lower Urinary Tract Complaints[NCT02886832] | 30 participants (Anticipated) | Interventional | 2016-09-21 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
17 trials available for glyburide and Glycosuria
| Article | Year |
|---|---|
[Combination therapy with insulin and sulfonylurea in secondary failure of sulfonylurea therapy].
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glyburide; Glycat | 1984 |
The combination of insulin and sulphonylurea in the treatment of secondary drug failure in patients with type II diabetes.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Drug The | 1984 |
Glibenclamide and gliquidone in the treatment of non-insulin-dependent diabetes mellitus.
Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Female; Glyburide; Glycated Hemogl | 1982 |
Efficacy of 24-week monotherapy with acarbose, glibenclamide, or placebo in NIDDM patients. The Essen Study.
Topics: Acarbose; Adult; Aged; Blood Glucose; Cholesterol; Cholesterol, HDL; Diabetes Mellitus, Type 2; Diet | 1994 |
More uniform diurnal blood glucose control and a reduction in daily insulin dosage on addition of glibenclamide to insulin in type 1 diabetes mellitus: role of enhanced insulin sensitivity.
Topics: Adult; Aged; Blood Glucose; Body Weight; C-Peptide; Cholesterol; Circadian Rhythm; Cross-Over Studie | 1995 |
[The effect of metipranolol on the carbohydrate metabolism in diabetics treated with glibenclamide (author's transl)].
Topics: Adult; Aged; Blood Glucose; Carbohydrate Metabolism; Clinical Trials as Topic; Diabetes Mellitus; Do | 1979 |
Clinical comparison between glibornuride (Glutril) and glibenclamide in maturity-onset diabetes: a controlled double-blind trial.
Topics: Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Dose-Response Relationship, Drug; | 1976 |
Clinical studies of the interaction between tolmetin and glibenclamide.
Topics: Adult; Aged; Blood Glucose; Diabetes Complications; Diabetes Mellitus; Drug Interactions; Female; Gl | 1977 |
Insulin, glibenclamide or metformin treatment for non insulin dependent diabetes: heterogenous responses of standard measures of insulin action and insulin secretion before and after differing hypoglycaemic therapy.
Topics: Blood Glucose; Body Mass Index; C-Peptide; Diabetes Mellitus, Type 2; Glucose Clamp Technique; Glybu | 1992 |
Combined glyburide and insulin therapy in type II diabetes.
Topics: Adult; Aged; Blood Glucose; C-Peptide; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Evaluat | 1987 |
Combination of two sulfonylureas. Does it make sense.
Topics: Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Diabetes Mellitus, Type 2; Drug Therapy, | 1988 |
Transient effect of the combination of insulin and sulfonylurea (glibenclamide) on glycemic control in non-insulin dependent diabetics poorly controlled with insulin alone.
Topics: Blood Glucose; Body Weight; C-Peptide; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Double-B | 1985 |
Once-daily use of glyburide.
Topics: Blood Glucose; Body Weight; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Administration Schedule; | 1985 |
Pharmacokinetics and metabolic effects of glibenclamide and glipizide in type 2 diabetics.
Topics: Aged; Blood Glucose; Body Weight; C-Peptide; Diabetes Mellitus, Type 2; Double-Blind Method; Erythro | 1985 |
[Blood sugar, serum insulin, nonesterified fatty acids and somatotropin in daily profile in adult diabetics under monotherapy with various sulfonylureas].
Topics: Blood Glucose; Body Weight; Diabetes Mellitus; Diet, Diabetic; Fatty Acids, Nonesterified; Glyburide | 1974 |
[Clinical testing of a sulphonylurea derivative, glibornuride].
Topics: Adult; Aged; Biguanides; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus; Diet Therapy; F | 1972 |
[Therapy of diabetes in adults using Glibornurid. Results and clinical studies].
Topics: Aged; Blood Glucose; Body Weight; Camphanes; Clinical Trials as Topic; Diabetes Mellitus; Drug Hyper | 1973 |
24 other studies available for glyburide and Glycosuria
| Article | Year |
|---|---|
Hypoglycaemic and hypolipidaemic effects of Withania somnifera root and leaf extracts on alloxan-induced diabetic rats.
Topics: Alloxan; Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Glycosuria; Hemoglobins | 2009 |
Antidiabetic and antioxidant potential of β-sitosterol in streptozotocin-induced experimental hyperglycemia.
Topics: Animals; Antioxidants; Blood Glucose; Catalase; Diabetes Mellitus, Experimental; Dose-Response Relat | 2011 |
Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents.
Topics: Administration, Oral; Animals; Behavior, Animal; Diabetes Mellitus; Disease Models, Animal; Exocytos | 2005 |
Anti-diabetic activity of SMK001, a poly herbal formula in streptozotocin induced diabetic rats: therapeutic study.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Dose-Response Relationship, Dr | 2006 |
Antihyperglycemic effect of umbelliferone in streptozotocin-diabetic rats.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Fructose-Bisphosphatase; Glucokinase; Gluco | 2006 |
Studies on the biochemical effects of glibenclamide on alloxan diabetic rabbits.
Topics: Animals; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Glyburide; Glycosuria; Lipid M | 1980 |
Branched-chain amino acids and alanine as indices of the metabolic control in type 1 (insulin-dependent) and type 2 (non-insulin-dependent) diabetic patients.
Topics: Alanine; Amino Acids, Branched-Chain; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; F | 1982 |
A case of diabetes following tibolone therapy.
Topics: Anabolic Agents; Blood Glucose; Climacteric; Combined Modality Therapy; Diabetes Mellitus, Type 2; D | 1994 |
Antiperoxide effect of S-allyl cysteine sulfoxide, an insulin secretagogue, in diabetic rats.
Topics: Animals; Blood Glucose; Catalase; Cysteine; Diabetes Mellitus, Experimental; Garlic; Glucose; Glybur | 1996 |
Effect of acarbose on blood glucose profiles and plasma 1,5-anhydro-d-glucitol in type 2 diabetes poorly controlled by sulfonylurea therapy.
Topics: Acarbose; Aged; Blood Glucose; Deoxyglucose; Diabetes Mellitus, Type 2; Female; Fructosamine; Glucos | 1996 |
[Effect of methylpyrazole-carboxylic acid on carbohydrate and lipid metabolisms in patients with diabetes mellitus].
Topics: Aged; Blood Glucose; Carbutamide; Cholesterol; Diabetes Mellitus; Drug Evaluation; Fatty Acids, None | 1975 |
Blood ketone body disappearance rate in diabetics and normals after rapid infusion of dl-3-hydroxybutyrate. Studies before and after diabetic treatment.
Topics: Acetoacetates; Adolescent; Adult; Aged; Blood Glucose; Diabetes Mellitus; Diabetes Mellitus, Type 1; | 1976 |
[Median-term (4 months) treatment with glibenclamide + metformin substituting for glibenclamide + fenformin lowers the lacticemia levels in type-2 diabetics (NIDDM)].
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Drug Evaluation; Drug Therapy, Combination; Female; | 1992 |
Effect of a sulfonylurea and insulin on energy expenditure in type II diabetes mellitus.
Topics: Blood Glucose; Blood Urea Nitrogen; C-Peptide; Diabetes Mellitus; Diabetes Mellitus, Type 2; Energy | 1988 |
[Effect of long-term therapy with sulfanylurea preparations on the relation of insulin secretion and the insulin-binding capacity of its receptors].
Topics: Blood Glucose; Chlorpropamide; Diabetes Mellitus, Type 2; Drug Evaluation; Female; Gliclazide; Gluco | 1988 |
[A comparison of intravenous tolbutamide and insulin administration during and after operation in patients with maturity-onset diabetes (author's transl)].
Topics: Administration, Oral; Age Factors; Aged; Anesthesia, General; Blood Glucose; Carbohydrates; Carbutam | 1974 |
An open comparative study of the efficacy and tolerance of a new antidiabetic agent: glipizide.
Topics: Blood Glucose; Chlorpropamide; Cyclohexanes; Diabetes Mellitus; Diet, Diabetic; Female; Glyburide; G | 1973 |
A dermatosis specifically associated with a tumour of pancreatic alpha cells.
Topics: Blister; Blood Glucose; Body Weight; Diabetes Complications; Female; Glucagon; Glucose; Glucose Tole | 1974 |
Mild familial diabetes with dominant inheritance.
Topics: Acetohexamide; Adolescent; Adult; Aged; Blood Glucose; Carbohydrates; Child; Chlorpropamide; Diabete | 1974 |
[The following of a diabetic patient treated by Euglucan].
Topics: Blood Glucose; Diabetes Mellitus; Follow-Up Studies; Glyburide; Glycosuria; Humans | 1972 |
[Oral antidiabetic therapy with delayed-action glibenclamide and phenformin in fixed combination].
Topics: Adult; Aged; Blood Glucose; Carbutamide; Cholesterol; Delayed-Action Preparations; Diabetes Mellitus | 1974 |
[Role of glibenclamide in the therapy of diabetes].
Topics: Adult; Chlorpropamide; Diabetes Mellitus; Evaluation Studies as Topic; Glyburide; Glycosuria; Humans | 1972 |
[Glibenclamide--a better antidiabetic agent?].
Topics: Aged; Blood Glucose; Body Weight; Chlorpropamide; Cholesterol; Diabetes Mellitus; Female; Glyburide; | 1972 |
Glibenclamide--experience at Royal Prince Alfred Hospital 1967-70.
Topics: Adult; Aged; Blood Glucose; Diabetes Mellitus; Glyburide; Glycosuria; Humans; Hypoglycemic Agents; M | 1971 |