glyburide has been researched along with Encephalopathy, Toxic in 3 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Chronic exposure to n-hexane, a widely used solvent in industry, causes sensorimotor neuropathy, which is mainly mediated by its toxic metabolite, 2,5-hexanedione (HD)." | 1.56 | Glibenclamide attenuates 2,5-hexanedione-induced neurotoxicity in the spinal cord of rats through mitigation of NLRP3 inflammasome activation, neuroinflammation and oxidative stress. ( Hou, L; Huang, R; Li, S; Wang, Q; Yang, J; Zhang, D; Zhao, J, 2020) |
| "Currently, whether nod-like receptor family pyrin domain-containing 3 (NLRP3) inflammasome activation contributes to neuropathy induced by 2,5-Hexanedione (HD), the toxic metabolite of n-hexane, remains unknown." | 1.56 | NLRP3 inflammasome mediates 2,5-hexanedione-induced neurotoxicity through regulation of macrophage infiltration in rats. ( Hou, L; Huang, R; Ruan, Z; Sun, W; Wang, Q; Zhang, D, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (66.67) | 2.80 |
| Authors | Studies |
|---|---|
| Hou, L | 2 |
| Yang, J | 1 |
| Li, S | 1 |
| Huang, R | 2 |
| Zhang, D | 2 |
| Zhao, J | 1 |
| Wang, Q | 2 |
| Ruan, Z | 1 |
| Sun, W | 1 |
| Kou, J | 1 |
| Klorig, DC | 1 |
| Bloomquist, JR | 1 |
3 other studies available for glyburide and Encephalopathy, Toxic
| Article | Year |
|---|---|
Glibenclamide attenuates 2,5-hexanedione-induced neurotoxicity in the spinal cord of rats through mitigation of NLRP3 inflammasome activation, neuroinflammation and oxidative stress.
Topics: Animals; Antioxidants; Glyburide; Hexanones; Inflammasomes; Male; Neuroprotective Agents; Neurotoxic | 2020 |
NLRP3 inflammasome mediates 2,5-hexanedione-induced neurotoxicity through regulation of macrophage infiltration in rats.
Topics: Animals; Antioxidants; Cell Movement; Glutathione; Glyburide; Hexanones; Inflammasomes; Intracellula | 2020 |
Potentiating effect of the ATP-sensitive potassium channel blocker glibenclamide on complex I inhibitor neurotoxicity in vitro and in vivo.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; Adenosine Triphosphate; Animals; Blotting, Western; Ca | 2006 |