glyburide has been researched along with Diabetic Retinopathy in 11 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Diabetic Retinopathy: Disease of the RETINA as a complication of DIABETES MELLITUS. It is characterized by the progressive microvascular complications, such as ANEURYSM, interretinal EDEMA, and intraocular PATHOLOGIC NEOVASCULARIZATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the dynamics of the intracellular Ca2+ concentration ([Ca2+]i) during retinal ischemia in rats with streptozotocin (STZ)-induced diabetes and the effect of gliclazide, a sulfonylurea with a potent free-radical scavenging activity on ischemia-induced [Ca2+]i dynamics." | 7.73 | Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. ( Harata, N; Kinukawa, J; Shimura, M; Tamai, M, 2005) |
| "The effects of long-term treatment with gliclazide on diabetic retinopathy and platelet adhesion were investigated." | 7.66 | Preventive and therapeutic effects of gliclazide on diabetic retinopathy: comparison with glibenclamide treatment. ( Abe, M; Ikeda, Y; Minami, N, 1983) |
| "Gliclazide has been reported to decrease platelet function and to inhibit the progression of diabetic retinopathy in addition to having a hypoglycemic effect." | 5.05 | Comparison of gliclazide and glibenclamide treatment in non-insulin-dependent diabetes. ( Baba, S; Fukui, I; Goto, Y; Maezawa, H; Nakagawa, S; Sakamoto, N; Takebe, K; Takeda, R, 1983) |
| "To investigate the dynamics of the intracellular Ca2+ concentration ([Ca2+]i) during retinal ischemia in rats with streptozotocin (STZ)-induced diabetes and the effect of gliclazide, a sulfonylurea with a potent free-radical scavenging activity on ischemia-induced [Ca2+]i dynamics." | 3.73 | Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes. ( Harata, N; Kinukawa, J; Shimura, M; Tamai, M, 2005) |
| "The effects of long-term treatment with gliclazide on diabetic retinopathy and platelet adhesion were investigated." | 3.66 | Preventive and therapeutic effects of gliclazide on diabetic retinopathy: comparison with glibenclamide treatment. ( Abe, M; Ikeda, Y; Minami, N, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (36.36) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 1 (9.09) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Wachal, Z | 1 |
| Bombicz, M | 1 |
| Priksz, D | 1 |
| Hegedűs, C | 1 |
| Kovács, D | 1 |
| Szabó, AM | 1 |
| Kiss, R | 1 |
| Németh, J | 1 |
| Juhász, B | 1 |
| Szilvássy, Z | 1 |
| Varga, B | 1 |
| Saberi, M | 1 |
| Ramazani, Z | 1 |
| Rashidi, H | 1 |
| Saberi, A | 1 |
| Berdugo, M | 1 |
| Delaunay, K | 1 |
| Naud, MC | 1 |
| Guegan, J | 1 |
| Moulin, A | 1 |
| Savoldelli, M | 1 |
| Picard, E | 1 |
| Radet, L | 1 |
| Jonet, L | 1 |
| Djerada, Z | 1 |
| Gozalo, C | 1 |
| Daruich, A | 1 |
| Beltrand, J | 1 |
| Jeanny, JC | 1 |
| Kermorvant-Duchemin, E | 1 |
| Crisanti, P | 1 |
| Polak, M | 1 |
| Behar-Cohen, F | 1 |
| Iafusco, D | 1 |
| Salardi, S | 1 |
| Chiari, G | 1 |
| Toni, S | 1 |
| Rabbone, I | 1 |
| Pesavento, R | 1 |
| Pasquino, B | 1 |
| de Benedictis, A | 1 |
| Maltoni, G | 1 |
| Colombo, C | 1 |
| Russo, L | 1 |
| Massa, O | 1 |
| Sudano, M | 1 |
| Cadario, F | 1 |
| Porta, M | 1 |
| Barbetti, F | 1 |
| Akimoto, Y | 1 |
| Sawada, H | 1 |
| Ohara-Imaizumi, M | 1 |
| Nagamatsu, S | 1 |
| Kawakami, H | 1 |
| Omori, Y | 1 |
| Kinukawa, J | 1 |
| Shimura, M | 1 |
| Harata, N | 1 |
| Tamai, M | 1 |
| Chan, TK | 1 |
| Chan, V | 1 |
| Teng, CS | 1 |
| Yeung, RT | 1 |
| Minami, N | 1 |
| Ikeda, Y | 1 |
| Abe, M | 1 |
| Baba, S | 1 |
| Nakagawa, S | 1 |
| Takebe, K | 1 |
| Goto, Y | 1 |
| Maezawa, H | 1 |
| Takeda, R | 1 |
| Sakamoto, N | 1 |
| Fukui, I | 1 |
| Soler, NG | 1 |
| Bennett, MA | 1 |
| Pentecost, BL | 1 |
| Fitzgerald, MG | 1 |
| Malins, JM | 1 |
1 review available for glyburide and Diabetic Retinopathy
| Article | Year |
|---|---|
[Medical management of pregnant women with diabetes].
Topics: Blood Glucose; Body Weight; Congenital Abnormalities; Diabetic Nephropathies; Diabetic Retinopathy; | 2002 |
2 trials available for glyburide and Diabetic Retinopathy
| Article | Year |
|---|---|
[Effects of gliclazide and glibenclamide on platelet function, fibrinolysis and metabolic control in diabetic patients with retinopathy (author's transl)].
Topics: Blood Glucose; Diabetic Retinopathy; Fibrinolysis; Gliclazide; Glyburide; Glycated Hemoglobin; Human | 1982 |
Comparison of gliclazide and glibenclamide treatment in non-insulin-dependent diabetes.
Topics: Adult; Aged; Blood Glucose; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Retinopath | 1983 |
8 other studies available for glyburide and Diabetic Retinopathy
| Article | Year |
|---|---|
Retinoprotection by BGP-15, a Hydroximic Acid Derivative, in a Type II Diabetic Rat Model Compared to Glibenclamide, Metformin, and Pioglitazone.
Topics: Animals; Blood Glucose; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Models, Animal; Ele | 2020 |
The Effect of CYP2C9 Genotype Variants in Type 2 Diabetes on the Pharmacological Effectiveness of Sulfonylureas, Diabetic Retinopathy, and Nephropathy.
Topics: Biomarkers; Blood Glucose; Cytochrome P-450 CYP2C9; Diabetes Mellitus, Type 2; Diabetic Nephropathie | 2020 |
The antidiabetic drug glibenclamide exerts direct retinal neuroprotection.
Topics: Administration, Oral; Animals; Chlorocebus aethiops; Diabetes Mellitus, Experimental; Diabetic Retin | 2021 |
No sign of proliferative retinopathy in 15 patients with permanent neonatal diabetes with a median diabetes duration of 24 years.
Topics: Adolescent; Adult; Diabetes Mellitus; Diabetic Retinopathy; Female; Follow-Up Studies; Glyburide; Hu | 2014 |
Change in long-spacing collagen in Descemet's membrane of diabetic Goto-Kakizaki rats and its suppression by antidiabetic agents.
Topics: Animals; Collagen; Cornea; Cyclohexanes; Descemet Membrane; Diabetes Mellitus, Experimental; Diabeti | 2008 |
Gliclazide attenuates the intracellular Ca2+ changes induced in vitro by ischemia in the retinal slices of rats with streptozotocin-induced diabetes.
Topics: Aniline Compounds; Animals; Calcium; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Gliclazi | 2005 |
Preventive and therapeutic effects of gliclazide on diabetic retinopathy: comparison with glibenclamide treatment.
Topics: Adult; Aged; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Female; Gliclazide; Glyburide; Humans; | 1983 |
Myocardial infarction in diabetics.
Topics: Administration, Oral; Adult; Aged; Chlorpropamide; Coronary Care Units; Diabetes Complications; Diab | 1975 |