Page last updated: 2024-10-28

glyburide and Developmental Disabilities

glyburide has been researched along with Developmental Disabilities in 8 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Developmental Disabilities: Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (50.00)29.6817
2010's4 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ioacara, S1
Flanagan, S1
Fröhlich-Reiterer, E1
Goland, R1
Fica, S1
Della Manna, T1
Battistim, C1
Radonsky, V1
Savoldelli, RD1
Damiani, D1
Kok, F1
Pearson, ER1
Ellard, S2
Hattersley, AT4
Reis, AF1
Mohamadi, A1
Clark, LM1
Lipkin, PH1
Mahone, EM1
Wodka, EL1
Plotnick, LP1
Jones, AG1
Sang, Y1
Ni, G1
Gu, Y1
Liu, M1
Slingerland, AS1
Nuboer, R1
Hadders-Algra, M1
Bruining, GJ1
Shimomura, K1
Hörster, F1
de Wet, H1
Flanagan, SE1
Wolf, NI1
Ashcroft, F1
Ebinger, F1
Mlynarski, W1
Tarasov, AI1
Gach, A1
Girard, CA1
Pietrzak, I1
Zubcevic, L1
Kusmierek, J1
Klupa, T1
Malecki, MT1
Ashcroft, FM1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Timing of Initiation of Sulphonylurea Therapy on Neurodevelopmental Outcomes in Individuals With Intermediate Developmental Delay, Epilepsy and Neonatal Diabetes (iDEND) Syndrome Due to the V59M Mutation in the KCNJ11 Gene[NCT05751525]21 participants (Anticipated)Observational2016-07-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

8 other studies available for glyburide and Developmental Disabilities

ArticleYear
First case of neonatal diabetes with KCNJ11 Q52R mutation successfully switched from insulin to sulphonylurea treatment.
    Journal of diabetes investigation, 2017, Volume: 8, Issue:5

    Topics: Developmental Disabilities; Diabetes Mellitus; Epilepsy; Glyburide; Humans; Hypoglycemic Agents; Inf

2017
Glibenclamide unresponsiveness in a Brazilian child with permanent neonatal diabetes mellitus and DEND syndrome due to a C166Y mutation in KCNJ11 (Kir6.2) gene.
    Arquivos brasileiros de endocrinologia e metabologia, 2008, Volume: 52, Issue:8

    Topics: Brazil; Child, Preschool; Developmental Disabilities; Diabetes Mellitus; Epilepsy; Female; Glyburide

2008
Medical and developmental impact of transition from subcutaneous insulin to oral glyburide in a 15-yr-old boy with neonatal diabetes mellitus and intermediate DEND syndrome: extending the age of KCNJ11 mutation testing in neonatal DM.
    Pediatric diabetes, 2010, Volume: 11, Issue:3

    Topics: Administration, Oral; Adolescent; Continuity of Patient Care; Developmental Disabilities; Diabetes M

2010
Reevaluation of a case of type 1 diabetes mellitus diagnosed before 6 months of age.
    Nature reviews. Endocrinology, 2010, Volume: 6, Issue:6

    Topics: Administration, Oral; Adolescent; Amino Acid Substitution; Developmental Disabilities; Diabetes Mell

2010
AV59M KCNJ11 gene mutation leading to intermediate DEND syndrome in a Chinese child.
    Journal of pediatric endocrinology & metabolism : JPEM, 2011, Volume: 24, Issue:9-10

    Topics: Asian People; Developmental Disabilities; Diabetes Mellitus, Type 1; Glyburide; Humans; Hypoglycemic

2011
Improved motor development and good long-term glycaemic control with sulfonylurea treatment in a patient with the syndrome of intermediate developmental delay, early-onset generalised epilepsy and neonatal diabetes associated with the V59M mutation in the
    Diabetologia, 2006, Volume: 49, Issue:11

    Topics: Amino Acid Substitution; Blood Glucose; Developmental Disabilities; Diabetes Mellitus; Epilepsy; Fol

2006
A novel mutation causing DEND syndrome: a treatable channelopathy of pancreas and brain.
    Neurology, 2007, Sep-25, Volume: 69, Issue:13

    Topics: Animals; Anticonvulsants; Cell Membrane; Child, Preschool; Developmental Disabilities; Diabetes Mell

2007
Sulfonylurea improves CNS function in a case of intermediate DEND syndrome caused by a mutation in KCNJ11.
    Nature clinical practice. Neurology, 2007, Volume: 3, Issue:11

    Topics: Child; Child, Preschool; Developmental Disabilities; Diabetes Mellitus; DNA Mutational Analysis; Fem

2007