Page last updated: 2024-10-28

glyburide and Death, Sudden, Cardiac

glyburide has been researched along with Death, Sudden, Cardiac in 5 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Death, Sudden, Cardiac: Unexpected rapid natural death due to cardiovascular collapse within one hour of initial symptoms. It is usually caused by the worsening of existing heart diseases. The sudden onset of symptoms, such as CHEST PAIN and CARDIAC ARRHYTHMIAS, particularly VENTRICULAR TACHYCARDIA, can lead to the loss of consciousness and cardiac arrest followed by biological death. (from Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine, 7th ed., 2005)

Research Excerpts

ExcerptRelevanceReference
" In this study, we investigated whether TZDs affect onset, spectral characteristics, and mortality of ischemic ventricular fibrillation (VF) and whether such effects are recapitulated by a non-selective K(ATP) blocker (glyburide) or a mitochondrial K(ATP) blocker (5-hydroxydecanoate)."3.78Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs. ( Greyson, CR; Lu, L; Reiter, MJ; Sarraf, M; Schwartz, GG; Ye, S, 2012)
"However, for the safe treatment of arrhythmias nearly all presently known blockers lack sufficient selectivity, either within the target family or with respect to other ion channels modulating the cardiac action potential."1.32Blockers of the ATP-sensitive potassium channel SUR2A/Kir6.2: a new approach to prevent sudden cardiac death. ( Englert, HC; Gerlach, U; Heitsch, H; Knieps, S, 2003)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's1 (20.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Dhopeshwarkar, N1
Brensinger, CM2
Bilker, WB2
Soprano, SE1
Flory, JH2
Dawwas, GK1
Gagne, JJ2
Hennessy, S2
Leonard, CE2
Aquilante, CL1
Boudreau, DM1
Deo, R1
Mangaali, MJ1
Sarraf, M1
Lu, L1
Ye, S1
Reiter, MJ1
Greyson, CR1
Schwartz, GG1
Englert, HC1
Heitsch, H1
Gerlach, U1
Knieps, S1
Link, MS1
Wang, PJ1
VanderBrink, BA1
Avelar, E1
Pandian, NG1
Maron, BJ1
Estes, NA1

Other Studies

5 other studies available for glyburide and Death, Sudden, Cardiac

ArticleYear
Risk of sudden cardiac arrest and ventricular arrhythmia with sulfonylureas: An experience with conceptual replication in two independent populations.
    Scientific reports, 2020, 06-22, Volume: 10, Issue:1

    Topics: Aged; Cohort Studies; Death, Sudden, Cardiac; Diabetes Mellitus, Type 2; Female; Glipizide; Glyburid

2020
Comparative Safety of Sulfonylureas and the Risk of Sudden Cardiac Arrest and Ventricular Arrhythmia.
    Diabetes care, 2018, Volume: 41, Issue:4

    Topics: Aged; Arrhythmias, Cardiac; Cause of Death; Death, Sudden, Cardiac; Diabetic Angiopathies; Female; G

2018
Thiazolidinedione drugs promote onset, alter characteristics, and increase mortality of ischemic ventricular fibrillation in pigs.
    Cardiovascular drugs and therapy, 2012, Volume: 26, Issue:3

    Topics: Animals; Anti-Arrhythmia Agents; Coronary Vessels; Death, Sudden, Cardiac; Decanoic Acids; Female; G

2012
Blockers of the ATP-sensitive potassium channel SUR2A/Kir6.2: a new approach to prevent sudden cardiac death.
    Current medicinal chemistry. Cardiovascular and hematological agents, 2003, Volume: 1, Issue:3

    Topics: Action Potentials; Adenosine Triphosphate; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; ATP-Binding

2003
Selective activation of the K(+)(ATP) channel is a mechanism by which sudden death is produced by low-energy chest-wall impact (Commotio cordis).
    Circulation, 1999, Jul-27, Volume: 100, Issue:4

    Topics: Adenosine Triphosphate; Animals; Death, Sudden, Cardiac; Electrocardiography; Glyburide; Potassium C

1999