glyburide has been researched along with Coronary Heart Disease in 50 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " On the other hand, treatment of obese patients with metformin significantly reduced the incidence of myocardial infarction and of mortality diabetes related." | 4.80 | [Should the occurrence of a first coronary event change the management of diabetes?]. ( Dubois-Laforgue, D; Timsit, J, 2000) |
| "We studied the effects of ATP-sensitive potassium channel (KATP) modulation on ischemic cardiac performance and reperfusion-induced ventricular fibrillation (VF), and assessed the contribution of KATP to the cardioprotective and anti-arrhythmic effect of the anti-hypertensive drug cicletanine." | 3.69 | KATP channel modulation in working rat hearts with coronary occlusion: effects of cromakalim, cicletanine, and glibenclamide. ( Droy-Lefaix, MT; Ferdinandy, P; Koltai, M; Szilvássy, Z; Tarrade, T, 1995) |
| "We investigated the effect of ATP-sensitive K+ channel (KATP) openers (pinacidil and cromakalim), and a KATP blocker (glibenclamide) on reperfusion-induced arrhythmias in pentobarbitone-anaesthetized rats." | 3.69 | KATP channel modulators increase survival rate during coronary occlusion-reperfusion in anaesthetized rats. ( Baczkó, I; Leprán, I; Papp, JG, 1997) |
| " In order to determine whether activation of adenosine triphosphate (ATP)-sensitive K+ channels exclusively explains the hypoxia- and ischaemia-induced action potential shortening, effects of tolbutamide and glibenclamide on changes in action potential duration (APD) during hypoxia, metabolic blockade or experimental ischaemia were examined in guinea-pig and canine isolated myocardium by standard microelectrode techniques." | 3.68 | Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium. ( Kanno, M; Nakaya, H; Takeda, Y; Tohse, N, 1991) |
| "Glimepiride is a new sulfonylurea for diabetes treatment which is supposed to impact less on extra-pancreatic ATP-dependent K+ channels than the conventional drug glibenclamide." | 2.69 | Sulfonylureas and ischaemic preconditioning; a double-blind, placebo-controlled evaluation of glimepiride and glibenclamide. ( Amann, FW; Boedeker, KH; Burger, W; Gruber, D; Harris, S; Kiowski, W; Klepzig, H; Kober, G; Luus, H; Matter, C; Schneider, H, 1999) |
| "Treatment with glyburide and metformin significantly decreased plasma glucose concentrations from 207 (76) to 134 (52) mg/dl (p<0." | 1.34 | Improvement in coronary vascular dysfunction produced with euglycaemic control in patients with type 2 diabetes. ( Cadenas, J; Facta, AD; Hsueh, WA; Prior, JO; Quinones, MJ; Schelbert, HR; Schindler, TH, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (10.00) | 18.7374 |
| 1990's | 31 (62.00) | 18.2507 |
| 2000's | 13 (26.00) | 29.6817 |
| 2010's | 1 (2.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hung, YC | 1 |
| Lin, CC | 1 |
| Wang, TY | 1 |
| Chang, MP | 1 |
| Sung, FC | 1 |
| Chen, CC | 1 |
| Lee, TM | 2 |
| Chou, TF | 2 |
| Tsai, CH | 2 |
| Lee, BH | 1 |
| Seo, HW | 1 |
| Yoo, SE | 1 |
| Faglia, E | 1 |
| Forlani, S | 1 |
| Tomai, F | 2 |
| De Paulis, R | 1 |
| Turani, F | 1 |
| Colella, DF | 1 |
| Nardi, P | 1 |
| De Notaris, S | 1 |
| Moscarelli, M | 1 |
| Magliano, G | 1 |
| Crea, F | 2 |
| Chiariello, L | 2 |
| Miura, T | 1 |
| Miki, T | 1 |
| Novakovic, A | 1 |
| Gojkovic-Bukarica, L | 1 |
| Peric, M | 2 |
| Nezic, D | 1 |
| Djukanovic, B | 2 |
| Markovic-Lipkovski, J | 1 |
| Heinle, H | 1 |
| Schindler, TH | 1 |
| Facta, AD | 1 |
| Prior, JO | 1 |
| Cadenas, J | 1 |
| Hsueh, WA | 1 |
| Quinones, MJ | 1 |
| Schelbert, HR | 1 |
| Bretzke, G | 1 |
| Yao, Z | 1 |
| Gross, GJ | 3 |
| Auchampach, JA | 2 |
| Hide, EJ | 1 |
| Piper, J | 1 |
| Thiemermann, C | 1 |
| Ferdinandy, P | 1 |
| Szilvássy, Z | 1 |
| Droy-Lefaix, MT | 1 |
| Tarrade, T | 1 |
| Koltai, M | 1 |
| Baczkó, I | 1 |
| Leprán, I | 1 |
| Papp, JG | 1 |
| Gojkoviíc Bukarica, L | 1 |
| Kazić, T | 1 |
| Sajić, Z | 1 |
| Panić, G | 1 |
| Bojić, M | 1 |
| Ishibashi, Y | 1 |
| Duncker, DJ | 1 |
| Zhang, J | 1 |
| Bache, RJ | 1 |
| Nakamura, N | 1 |
| Hamazaki, T | 1 |
| Jokaji, H | 1 |
| Minami, S | 1 |
| Kobayashi, M | 1 |
| Köppel, H | 1 |
| Horn, S | 1 |
| Pieber, T | 1 |
| Grisold, M | 1 |
| Klein, W | 1 |
| Gasser, R | 1 |
| Wolk, R | 1 |
| Cobbe, SM | 2 |
| Kane, KA | 1 |
| Hicks, MN | 2 |
| Danesi, A | 1 |
| Ghini, AS | 1 |
| Perino, M | 1 |
| Gaspardone, A | 1 |
| Ruggeri, G | 1 |
| Gioffrè, PA | 1 |
| Klepzig, H | 1 |
| Kober, G | 1 |
| Matter, C | 1 |
| Luus, H | 1 |
| Schneider, H | 2 |
| Boedeker, KH | 1 |
| Kiowski, W | 1 |
| Amann, FW | 1 |
| Gruber, D | 1 |
| Harris, S | 1 |
| Burger, W | 1 |
| Workman, AJ | 1 |
| MacKenzie, I | 1 |
| Northover, BJ | 1 |
| Timsit, J | 1 |
| Dubois-Laforgue, D | 1 |
| Kesavulu, MM | 1 |
| Rao, BK | 1 |
| Giri, R | 1 |
| Vijaya, J | 1 |
| Subramanyam, G | 1 |
| Apparao, C | 1 |
| Fisman, EZ | 1 |
| Tenenbaum , A | 1 |
| Boyko, V | 1 |
| Benderly, M | 1 |
| Adler, Y | 1 |
| Friedensohn, A | 1 |
| Kohanovski, M | 1 |
| Rotzak, R | 1 |
| Behar, S | 1 |
| Motro, M | 1 |
| Skrapari, I | 1 |
| Perrea, D | 1 |
| Ioannidis, I | 1 |
| Karabina, SA | 1 |
| Elisaf, M | 1 |
| Tselepis, AD | 1 |
| Karagiannacos, P | 1 |
| Katsilambros, N | 1 |
| Su, SF | 1 |
| Lee, YT | 1 |
| Liu, Y | 1 |
| Downey, JM | 1 |
| Grover, GJ | 5 |
| Sleph, PG | 5 |
| Dzwonczyk, S | 4 |
| Cacciapuoti, F | 1 |
| Spiezia, R | 1 |
| Bianchi, U | 1 |
| Lama, D | 1 |
| D'Avino, M | 1 |
| Varricchio, M | 1 |
| Mitani, A | 1 |
| Kinoshita, K | 1 |
| Fukamachi, K | 1 |
| Sakamoto, M | 1 |
| Kurisu, K | 1 |
| Tsuruhara, Y | 1 |
| Fukumura, F | 1 |
| Nakashima, A | 1 |
| Tokunaga, K | 1 |
| Ohta, H | 1 |
| Jinno, Y | 1 |
| Harada, K | 1 |
| Ogawa, N | 1 |
| Fukushima, H | 1 |
| Nishikori, K | 1 |
| Cole, WC | 1 |
| McPherson, CD | 1 |
| Sontag, D | 1 |
| Venkatesh, N | 1 |
| Lamp, ST | 1 |
| Weiss, JN | 1 |
| Nakaya, H | 1 |
| Takeda, Y | 1 |
| Tohse, N | 1 |
| Kanno, M | 1 |
| Sargent, CA | 1 |
| Smith, MA | 1 |
| Komaru, T | 1 |
| Lamping, KG | 1 |
| Eastham, CL | 1 |
| Dellsperger, KC | 1 |
| McCullough, JR | 2 |
| Normandin, DE | 1 |
| Conder, ML | 2 |
| Kantor, PF | 1 |
| Coetzee, WA | 1 |
| Carmeliet, EE | 1 |
| Dennis, SC | 1 |
| Opie, LH | 1 |
| Bekheit, SS | 1 |
| Restivo, M | 1 |
| Boutjdir, M | 1 |
| Henkin, R | 1 |
| Gooyandeh, K | 1 |
| Assadi, M | 1 |
| Khatib, S | 1 |
| Gough, WB | 1 |
| el-Sherif, N | 1 |
| Wilde, AA | 2 |
| Escande, D | 2 |
| Schumacher, CA | 2 |
| Thuringer, D | 2 |
| Mestre, M | 2 |
| Fiolet, JW | 2 |
| Janse, MJ | 1 |
| Smallwood, JK | 1 |
| Ertel, PJ | 1 |
| Steinberg, MI | 1 |
| Gasser, RN | 1 |
| Vaughan-Jones, RD | 1 |
| Wolleben, CD | 1 |
| Sanguinetti, MC | 1 |
| Siegl, PK | 1 |
| Henry, DE | 1 |
| Marble, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals[NCT05423470] | 41 participants (Actual) | Interventional | 2019-05-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for glyburide and Coronary Heart Disease
| Article | Year |
|---|---|
[Antidiabetic therapy in diabetic patients with coronary heart disease].
Topics: Administration, Oral; Coronary Disease; Delayed-Action Preparations; Diabetes Complications; Diabete | 2003 |
ATP-sensitive K+ channel openers: old drugs with new clinical benefits for the heart.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Diazoxide; Glyburide; Human | 2003 |
ATP-sensitive K+ channels, adenosine, and nitric oxide-mediated mechanisms account for coronary vasodilation during exercise.
Topics: Adenosine; Adenosine Triphosphate; Animals; Coronary Disease; Coronary Vessels; Dogs; Enzyme Inhibit | 1998 |
[Should the occurrence of a first coronary event change the management of diabetes?].
Topics: Acidosis, Lactic; Acute Disease; Adrenergic beta-Antagonists; Blood Glucose; Cardiovascular Agents; | 2000 |
Glibenclamide, a new sulphonylurea: whither oral hypoglycaemic agents?
Topics: Administration, Oral; Adolescent; Adult; Blood Glucose; Carbohydrates; Child; Coronary Disease; Diab | 1971 |
9 trials available for glyburide and Coronary Heart Disease
| Article | Year |
|---|---|
Differential role of K(ATP) channels activated by conjugated estrogens in the regulation of myocardial and coronary protective effects.
Topics: Adenosine Triphosphate; Angioplasty, Balloon, Coronary; Cardiotonic Agents; Chest Pain; Coronary Dis | 2003 |
Preoperative shift from glibenclamide to insulin is cardioprotective in diabetic patients undergoing coronary artery bypass surgery.
Topics: Aged; Anesthetics, Inhalation; Angina Pectoris; Cardiotonic Agents; Coronary Disease; Creatine Kinas | 2004 |
Effect of HMG-CoA reductase inhibitors on plasma polyunsaturated fatty acid concentrations in patients with hyperlipidemia.
Topics: Aged; Cholesterol; Coronary Disease; Diabetes Mellitus, Type 2; Fatty Acids, Unsaturated; Female; Gl | 1998 |
Observations on the effect of glibenclamide on noninvasive clinical parameters of myocardial ischemia.
Topics: Blood Pressure; Coronary Disease; Diabetes Mellitus, Type 2; Glyburide; Humans; Insulin; Myocardial | 1998 |
Effects of K(ATP) channel blockade by glibenclamide on the warm-up phenomenon.
Topics: Adenosine Triphosphate; Administration, Oral; Adult; Aged; Coronary Disease; Electrocardiography; Ex | 1999 |
Sulfonylureas and ischaemic preconditioning; a double-blind, placebo-controlled evaluation of glimepiride and glibenclamide.
Topics: Adult; Aged; Angioplasty, Balloon, Coronary; Coronary Disease; Double-Blind Method; Electrocardiogra | 1999 |
Glibenclamide improves postprandial hypertriglyceridaemia in type 2 diabetic patients by reducing chylomicrons but not the very low-density lipoprotein subfraction levels.
Topics: Adult; Area Under Curve; Blood Glucose; C-Peptide; Cholesterol; Chylomicrons; Coronary Disease; Diab | 2001 |
Loss of preconditioning by attenuated activation of myocardial ATP-sensitive potassium channels in elderly patients undergoing coronary angioplasty.
Topics: Adult; Aged; Aging; Angioplasty, Balloon, Coronary; ATP-Binding Cassette Transporters; Chest Pain; C | 2002 |
Effectiveness of glibenclamide on myocardial ischemic ventricular arrhythmias in non-insulin-dependent diabetes mellitus.
Topics: Adult; Angina Pectoris; Blood Glucose; Cardiac Complexes, Premature; Coronary Disease; Diabetes Mell | 1991 |
36 other studies available for glyburide and Coronary Heart Disease
| Article | Year |
|---|---|
Oral hypoglycaemic agents and the development of non-fatal cardiovascular events in patients with type 2 diabetes mellitus.
Topics: Administration, Oral; Adult; Aged; Cardiovascular Diseases; Cohort Studies; Comorbidity; Coronary Di | 2013 |
Cardioprotective effects of (2S,3R,4S)-N'-benzyl-N"-cyano-N-(3,4-dihydro-2-dimethoxymethyl-3-hydroxy-2-methyl-6-nitro-2H-benzopyran-4-yl)-guanidine (KR-31372) in rats and dogs.
Topics: Animals; Benzopyrans; Cardiovascular Agents; Coronary Circulation; Coronary Disease; Dogs; Dose-Resp | 2004 |
The mechanism of endothelium-independent relaxation induced by the wine polyphenol resveratrol in human internal mammary artery.
Topics: 4-Aminopyridine; Anti-Arrhythmia Agents; Charybdotoxin; Coronary Artery Bypass; Coronary Disease; Gl | 2006 |
Improvement in coronary vascular dysfunction produced with euglycaemic control in patients with type 2 diabetes.
Topics: Blood Glucose; Blood Pressure; Case-Control Studies; Coronary Circulation; Coronary Disease; Diabete | 2007 |
[Effect of beta receptor blockers on carbohydrate metabolism].
Topics: Adrenergic beta-Antagonists; Aged; Blood Glucose; Carbohydrate Metabolism; Coronary Disease; Diabete | 1981 |
The ATP-dependent potassium channel: an endogenous cardioprotective mechanism.
Topics: Acetylcholine; Adenosine; Animals; Anti-Arrhythmia Agents; Coronary Disease; Decanoic Acids; Disease | 1994 |
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; D | 1993 |
Endothelin-1-induced reduction of myocardial infarct size by activation of ATP-sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arterial Occlusive Diseases; Blood Pressure | 1995 |
KATP channel modulation in working rat hearts with coronary occlusion: effects of cromakalim, cicletanine, and glibenclamide.
Topics: Animals; Anti-Arrhythmia Agents; Benzopyrans; Coronary Circulation; Coronary Disease; Cromakalim; Gl | 1995 |
KATP channel modulators increase survival rate during coronary occlusion-reperfusion in anaesthetized rats.
Topics: Action Potentials; Adenosine Triphosphate; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Ar | 1997 |
The effects of levcromakalim and pinacidil on the human internal mammary artery.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Apamin; Charybdotoxin; Coronary Artery Bypass; Coronary Dis | 1997 |
Relevance of inter- and intraventricular electrical dispersion to arrhythmogenesis in normal and ischaemic rabbit myocardium: a study with cromakalim, 5-hydroxydecanoate and glibenclamide.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Coronary Disease; Cromakal | 1999 |
Do KATP channels open as a prominent and early feature during ischaemia in the Langendorff-perfused rat heart?
Topics: Action Potentials; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzopyrans; Coronary Dise | 2000 |
Lipid peroxidation and antioxidant enzyme status in Type 2 diabetics with coronary heart disease.
Topics: Catalase; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Cholesterol, VLDL; Coronary Disease; Diab | 2001 |
Oral antidiabetic treatment in patients with coronary disease: time-related increased mortality on combined glyburide/metformin therapy over a 7.7-year follow-up.
Topics: Administration, Oral; Coronary Disease; Diabetes Mellitus, Type 2; Female; Follow-Up Studies; Glybur | 2001 |
Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Female | 1992 |
Ischemic preconditioning protects against infarction in rat heart.
Topics: Adaptation, Physiological; Adenosine; Animals; Coronary Disease; Glyburide; Heart; In Vitro Techniqu | 1992 |
Pharmacologic profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dogs.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Benzopyrans; Blood Pressure; Cardiovascular Agents; Cor | 1990 |
Effects of glibenclamide and nicorandil on cardiac function during ischemia and reperfusion in isolated perfused rat hearts.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Glyburide; Heart; Kinetics; Male; Myocardial Cont | 1991 |
Cardioprotective effects of KRN2391 and nicorandil on ischemic dysfunction in perfused rat heart.
Topics: Animals; Coronary Disease; Cytosol; Glyburide; Heart Rate; In Vitro Techniques; Male; Myocardium; Ni | 1991 |
Effect of glibenclamide on extracellular potassium accumulation and the electrophysiological changes during myocardial ischaemia in the arterially perfused interventricular septum of rabbit.
Topics: Action Potentials; Animals; Coronary Disease; Electrophysiology; Glyburide; Heart Septum; Membrane P | 1991 |
ATP-regulated K+ channels protect the myocardium against ischemia/reperfusion damage.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Disease; Glyburide; Guanidines; Guinea | 1991 |
Sulfonylureas, ATP-sensitive K+ channels, and cellular K+ loss during hypoxia, ischemia, and metabolic inhibition in mammalian ventricle.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Binding Sites; Coronary Disease; Female; Glyburi | 1991 |
Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Fe | 1991 |
Effect of potassium channel blockade on the anti-ischemic actions of mechanistically diverse agents.
Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzopyrans; Coronary Circulation; Coronar | 1991 |
Role of ATP-sensitive potassium channels in coronary microvascular autoregulatory responses.
Topics: Adenosine Triphosphate; Animals; Arterioles; Coronary Circulation; Coronary Disease; Dogs; Female; G | 1991 |
Specific block of the anti-ischemic actions of cromakalim by sodium 5-hydroxydecanoate.
Topics: Animals; Benzopyrans; Coronary Disease; Cromakalim; Decanoic Acids; Electrophysiology; Glyburide; He | 1991 |
Reduction of ischemic K+ loss and arrhythmias in rat hearts. Effect of glibenclamide, a sulfonylurea.
Topics: Animals; Arrhythmias, Cardiac; Coronary Disease; Glyburide; Heart; Lactates; Lactic Acid; Male; Myoc | 1990 |
Effects of glyburide on ischemia-induced changes in extracellular potassium and local myocardial activation: a potential new approach to the management of ischemia-induced malignant ventricular arrhythmias.
Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Coronary Disease; Dogs; Electrocardiography; Glyburide | 1990 |
Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Disease; Dinitrophenols; Electric Condu | 1990 |
Modification by glibenclamide of the electrophysiological consequences of myocardial ischaemia in dogs and rabbits.
Topics: Action Potentials; Animals; Blood Pressure; Coronary Disease; Coronary Vessels; Dogs; Electrophysiol | 1990 |
Reduction of ischemic damage in isolated rat hearts by the potassium channel opener, RP 52891.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Decanoic Acids; Glyburide; Heart; Hydroxy Acids; | 1990 |
Mechanism of potassium efflux and action potential shortening during ischaemia in isolated mammalian cardiac muscle.
Topics: Action Potentials; Animals; Bumetanide; Chlorides; Coronary Disease; Coumaric Acids; Deoxyglucose; F | 1990 |
Influence of ATP-sensitive potassium channel modulators on ischemia-induced fibrillation in isolated rat hearts.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Arrhythmias, Cardiac; Benzopyrans; Coronar | 1989 |
Glibenclamide inhibition of ATP-sensitive K+ channels and ischemia-induced K+ accumulation in the mammalian heart.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Glyburide; Guinea Pigs; Heart; Myocardium; Potass | 1989 |
Anti-ischemic effects of the potassium channel activators pinacidil and cromakalim and the reversal of these effects with the potassium channel blocker glyburide.
Topics: Animals; Antihypertensive Agents; Benzopyrans; Coronary Disease; Cromakalim; Glyburide; Guanidines; | 1989 |