Page last updated: 2024-10-28

glyburide and Cognition Disorders

glyburide has been researched along with Cognition Disorders in 6 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Cognition Disorders: Disorders characterized by disturbances in mental processes related to learning, thinking, reasoning, and judgment.

Research Excerpts

ExcerptRelevanceReference
"Meanwhile, cerebral edema, as well as neuronal loss, was decreased in several brain areas in the GBC group."1.46Glibenclamide ameliorates cerebral edema and improves outcomes in a rat model of status epilepticus. ( Gu, Y; Hu, Y; Huang, H; Huang, K; Ji, Z; Lin, Z; Pan, S; Wang, S; Wu, Y; Yang, T, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (16.67)29.6817
2010's5 (83.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, Z1
Huang, H1
Gu, Y1
Huang, K1
Hu, Y1
Ji, Z1
Wu, Y1
Wang, S1
Yang, T1
Pan, S1
Areosa Sastre, A1
Vernooij, RW1
González-Colaço Harmand, M1
Martínez, G1
Heyer, EJ1
Mergeche, JL1
Bruce, SS1
Connolly, ES1
Tosun, C1
Kurland, DB1
Mehta, R1
Castellani, RJ1
deJong, JL1
Kwon, MS1
Woo, SK1
Gerzanich, V1
Simard, JM1
Dalan, R1
Leow, MK1
George, J1
Chian, KY1
Tan, A1
Han, HW1
Cheow, SP1
Baraka, A1
ElGhotny, S1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Augmentation of Cerebral Blood Flow on Neuropsychometric Performance After Carotid Endarterectomy in Type II Diabetic Patients[NCT00597545]10 participants (Actual)Interventional2007-03-31Terminated (stopped due to Half of DM patients had EEG changes and therefore were excluded.)
Neurologic and Neuropsychometric Outcome in Patients Undergoing Carotid Endarterectomy[NCT00597883]585 participants (Actual)Observational2003-03-31Completed
A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden[NCT02501434]Phase 288 participants (Anticipated)Interventional2016-04-30Suspended
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants With Improved Neuropsychometric Changes

Battery of neuropsychometric tests to evaluate a variety of cognitive functions. (NCT00597545)
Timeframe: Post-operatively at 1 day

Interventionparticipants (Number)
Conventional Shunt1
Prophylactic Shunt2

Reviews

1 review available for glyburide and Cognition Disorders

ArticleYear
Effect of the treatment of Type 2 diabetes mellitus on the development of cognitive impairment and dementia.
    The Cochrane database of systematic reviews, 2017, 06-15, Volume: 6

    Topics: Carbamates; Cause of Death; Cognition Disorders; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypog

2017

Other Studies

5 other studies available for glyburide and Cognition Disorders

ArticleYear
Glibenclamide ameliorates cerebral edema and improves outcomes in a rat model of status epilepticus.
    Neuropharmacology, 2017, Jul-15, Volume: 121

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Cognition Disorders; Disease Models, Animal; Gene

2017
Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.
    Diabetes care, 2013, Volume: 36, Issue:10

    Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Glyburide; Humans; Hy

2013
Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.
    Diabetes care, 2013, Volume: 36, Issue:10

    Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Glyburide; Humans; Hy

2013
Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.
    Diabetes care, 2013, Volume: 36, Issue:10

    Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Glyburide; Humans; Hy

2013
Inflammation and cognitive dysfunction in type 2 diabetic carotid endarterectomy patients.
    Diabetes care, 2013, Volume: 36, Issue:10

    Topics: Aged; Cognition Disorders; Diabetes Mellitus, Type 2; Endarterectomy, Carotid; Glyburide; Humans; Hy

2013
Inhibition of the Sur1-Trpm4 channel reduces neuroinflammation and cognitive impairment in subarachnoid hemorrhage.
    Stroke, 2013, Volume: 44, Issue:12

    Topics: Animals; Brain; Cognition Disorders; Encephalitis; Glyburide; Humans; Maze Learning; Rats; Subarachn

2013
Neuroglycopenia and adrenergic responses to hypoglycaemia: insights from a local epidemic of serendipitous massive overdose of glibenclamide.
    Diabetic medicine : a journal of the British Diabetic Association, 2009, Volume: 26, Issue:1

    Topics: Adult; Aged; Asia, Southeastern; Blood Glucose; China; Cognition Disorders; Drugs, Chinese Herbal; G

2009
Study of the effect of inhibiting galanin in Alzheimer's disease induced in rats.
    European journal of pharmacology, 2010, Sep-01, Volume: 641, Issue:2-3

    Topics: Administration, Oral; Alzheimer Disease; Amyloid beta-Peptides; Animals; Avoidance Learning; Brain;

2010