glyburide has been researched along with Cirrhosis in 7 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Decorin is a small proteoglycan, composed of 12 leucine-rich repeats (LRRs) that modulates the activity of transforming growth factor type β (TGF-β) and other growth factors, and thereby influences proliferation and differentiation in a wide array of physiological and pathological processes, such as fibrosis, in several tissues and organs." | 3.78 | The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscles. ( Acuña, MJ; Brandan, E; Cabello-Verrugio, C; Cofré, C; Melo, F; Santander, C, 2012) |
| "Cardiac fibrosis was induced in male Sprague Dawley rats by uninephrectomy and by subsequent administration of deoxycorticosterone acetate (DOCA) every 4th day till 28 days along with 1% NaCl in drinking water." | 1.91 | Repositioning Glibenclamide in cardiac fibrosis by targeting TGF-β1-pSmad2/3-NLRP3 cascade. ( Chandel, A; Gandhi, T; Gupta, D; Pandya, H; Patel, A, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (28.57) | 29.6817 |
| 2010's | 3 (42.86) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Gandhi, T | 1 |
| Patel, A | 1 |
| Gupta, D | 1 |
| Pandya, H | 1 |
| Chandel, A | 1 |
| Wu, X | 1 |
| Liu, Y | 1 |
| Tu, D | 1 |
| Liu, X | 1 |
| Niu, S | 1 |
| Suo, Y | 1 |
| Liu, T | 1 |
| Li, G | 1 |
| Liu, C | 1 |
| Hughes, FM | 1 |
| Sexton, SJ | 1 |
| Jin, H | 1 |
| Govada, V | 1 |
| Purves, JT | 1 |
| Hashimoto, Y | 1 |
| Shuto, T | 1 |
| Mizunoe, S | 1 |
| Tomita, A | 1 |
| Koga, T | 1 |
| Sato, T | 1 |
| Takeya, M | 1 |
| Suico, MA | 1 |
| Niibori, A | 1 |
| Sugahara, T | 1 |
| Shimasaki, S | 1 |
| Sugiyama, T | 1 |
| Scholte, B | 1 |
| Kai, H | 1 |
| Cabello-Verrugio, C | 1 |
| Santander, C | 1 |
| Cofré, C | 1 |
| Acuña, MJ | 1 |
| Melo, F | 1 |
| Brandan, E | 1 |
| Wardle, EN | 1 |
| Shi, YX | 1 |
| Chen, Y | 1 |
| Zhu, YZ | 1 |
| Huang, GY | 1 |
| Moore, PK | 1 |
| Huang, SH | 1 |
| Yao, T | 1 |
| Zhu, YC | 1 |
7 other studies available for glyburide and Cirrhosis
| Article | Year |
|---|---|
Repositioning Glibenclamide in cardiac fibrosis by targeting TGF-β1-pSmad2/3-NLRP3 cascade.
Topics: Animals; Desoxycorticosterone Acetate; Fibrosis; Glyburide; Inflammasomes; Male; NLR Family, Pyrin D | 2023 |
Role of NLRP3-Inflammasome/Caspase-1/Galectin-3 Pathway on Atrial Remodeling in Diabetic Rabbits.
Topics: Alloxan; Animals; Anti-Inflammatory Agents; Atrial Fibrillation; Atrial Function, Left; Atrial Remod | 2020 |
Bladder fibrosis during outlet obstruction is triggered through the NLRP3 inflammasome and the production of IL-1β.
Topics: Animals; Autocrine Communication; Cells, Cultured; Disease Models, Animal; Female; Fibrillar Collage | 2017 |
CFTR-deficiency renders mice highly susceptible to cutaneous symptoms during mite infestation.
Topics: Animals; Cells, Cultured; Chloride Channels; Cystic Fibrosis Transmembrane Conductance Regulator; Di | 2011 |
The internal region leucine-rich repeat 6 of decorin interacts with low density lipoprotein receptor-related protein-1, modulates transforming growth factor (TGF)-β-dependent signaling, and inhibits TGF-β-dependent fibrotic response in skeletal muscles.
Topics: Animals; Cell Line; CHO Cells; Cricetinae; Decorin; Endocytosis; Fibrosis; Glyburide; Humans; Leucin | 2012 |
Up-date on renal fibrosis: a time for action.
Topics: Cell Proliferation; Disease Progression; Extracellular Matrix; Fibrosis; Glyburide; Humans; Hypoglyc | 2007 |
Chronic sodium hydrosulfide treatment decreases medial thickening of intramyocardial coronary arterioles, interstitial fibrosis, and ROS production in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Cardiomegaly; Cardiotonic | 2007 |