glyburide has been researched along with Chemical and Drug Induced Liver Injury in 21 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Chemical and Drug Induced Liver Injury: A spectrum of clinical liver diseases ranging from mild biochemical abnormalities to ACUTE LIVER FAILURE, caused by drugs, drug metabolites, herbal and dietary supplements and chemicals from the environment.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 7.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "Dietary supplementation with CM fruits effectively prevents the development of diabetes mellitus, dyslipidemia and hepatic inflammation in alloxan-induced diabetes." | 3.80 | Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats. ( Asgary, S; Najafi, S; Rafieian-Kopaei, M; Sahebkar, A; Shamsi, F, 2014) |
| "This study investigated the role of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain." | 3.79 | The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats. ( Afify, EA; Khedr, MM; Nasser, SA; Omar, AG, 2013) |
| "Glyburide can produce an acute hepatitis-like illness in some persons." | 1.27 | Glyburide-induced hepatitis. ( Dean, PJ; Goodman, RC; Kitabchi, AE; Radparvar, A, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (9.52) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 2 (9.52) | 29.6817 |
| 2010's | 11 (52.38) | 24.3611 |
| 2020's | 2 (9.52) | 2.80 |
| Authors | Studies |
|---|---|
| Fourches, D | 1 |
| Barnes, JC | 1 |
| Day, NC | 1 |
| Bradley, P | 1 |
| Reed, JZ | 1 |
| Tropsha, A | 1 |
| Morgan, RE | 2 |
| Trauner, M | 1 |
| van Staden, CJ | 2 |
| Lee, PH | 1 |
| Ramachandran, B | 1 |
| Eschenberg, M | 1 |
| Afshari, CA | 2 |
| Qualls, CW | 1 |
| Lightfoot-Dunn, R | 1 |
| Hamadeh, HK | 2 |
| Dawson, S | 1 |
| Stahl, S | 2 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 2 |
| Liu, Z | 1 |
| Shi, Q | 1 |
| Ding, D | 1 |
| Kelly, R | 1 |
| Fang, H | 1 |
| Tong, W | 2 |
| Warner, DJ | 1 |
| Chen, H | 1 |
| Cantin, LD | 1 |
| Walker, CL | 1 |
| Noeske, T | 1 |
| Chen, Y | 1 |
| Kalyanaraman, N | 1 |
| Kalanzi, J | 1 |
| Dunn, RT | 1 |
| Aleo, MD | 1 |
| Luo, Y | 1 |
| Swiss, R | 1 |
| Bonin, PD | 1 |
| Potter, DM | 1 |
| Will, Y | 1 |
| Chen, M | 1 |
| Suzuki, A | 1 |
| Thakkar, S | 1 |
| Yu, K | 1 |
| Hu, C | 1 |
| Norman, BH | 1 |
| Abrar, H | 1 |
| Arsalan, A | 1 |
| Yasin, H | 1 |
| Zaidi, SIH | 1 |
| Ibrahim, S | 1 |
| Qadeer, K | 1 |
| Naeem, H | 1 |
| Fatima, K | 1 |
| Tabassum, H | 1 |
| Naqvi, SNH | 1 |
| Dwivedi, DK | 1 |
| Jena, GB | 1 |
| Asgary, S | 1 |
| Rafieian-Kopaei, M | 1 |
| Shamsi, F | 1 |
| Najafi, S | 1 |
| Sahebkar, A | 1 |
| Tolman, KG | 1 |
| Freston, JW | 1 |
| Kupfer, S | 1 |
| Perez, A | 1 |
| Afify, EA | 1 |
| Khedr, MM | 1 |
| Omar, AG | 1 |
| Nasser, SA | 1 |
| Li, Z | 1 |
| Agellon, LB | 1 |
| Vance, DE | 1 |
| Pérez-Roldán, F | 1 |
| Aguirre, A | 1 |
| Bañares, R | 1 |
| Casado, M | 1 |
| González-Asanza, C | 1 |
| Alvarez, E | 1 |
| Clemente, G | 1 |
| Saw, D | 1 |
| Pitman, E | 1 |
| Maung, M | 1 |
| Savasatit, P | 1 |
| Wasserman, D | 1 |
| Yeung, CK | 1 |
| Petrogiannopoulos, C | 1 |
| Zacharof, A | 1 |
| van Basten, JP | 1 |
| van Hoek, B | 1 |
| Zeijen, R | 1 |
| Stockbrügger, R | 1 |
| Meadow, P | 1 |
| Tullio, CJ | 1 |
| Goodman, RC | 1 |
| Dean, PJ | 1 |
| Radparvar, A | 1 |
| Kitabchi, AE | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Comparator Controlled, Double-Blind Study of the Liver Safety of Pioglitazone HCl vs Glyburide With Metformin and Insulin as Part of Step Therapy in Subjects With Type 2 (Non-Insulin Dependent) Diabetes[NCT00494312] | Phase 4 | 2,120 participants (Actual) | Interventional | 2000-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for glyburide and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Pr | 2016 |
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies.
Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Eval | 2020 |
[Cholestatic hepatitis caused by glybenclamide in a patient with hepatitis C virus].
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis, Intrahepatic; Glyburide; Hepatitis C; Hum | 1995 |
Granulomatous hepatitis associated with glyburide.
Topics: Chemical and Drug Induced Liver Injury; Glyburide; Granuloma; Humans; Hypoglycemic Agents; Male; Mid | 1996 |
Glyburide-induced cholestatic hepatitis and liver failure. Case-report and review of the literature.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Glyburide; Humans | 1992 |
1 trial available for glyburide and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Liver safety in patients with type 2 diabetes treated with pioglitazone: results from a 3-year, randomized, comparator-controlled study in the US.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Blood Glucose; Chemical and Drug Induced Liver Injury; D | 2009 |
15 other studies available for glyburide and Chemical and Drug Induced Liver Injury
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLI | 2010 |
Interference with bile salt export pump function is a susceptibility factor for human liver injury in drug development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2010 |
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da | 2011 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily | 2013 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2014 |
The novel effect of propranolol in glibenclamide induced hepatotoxicity.
Topics: Alanine Transaminase; Alkaline Phosphatase; Animals; Antioxidants; Aspartate Aminotransferases; Bili | 2020 |
Glibenclamide protects against thioacetamide-induced hepatic damage in Wistar rat: investigation on NLRP3, MMP-2, and stellate cell activation.
Topics: Animals; Chemical and Drug Induced Liver Injury; DNA Damage; Glyburide; Hepatic Stellate Cells; Hypo | 2018 |
Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats.
Topics: Alkaline Phosphatase; Alloxan; Animals; Anthocyanins; Blood Glucose; Chemical and Drug Induced Liver | 2014 |
The involvement of K(ATP) channels in morphine-induced antinociception and hepatic oxidative stress in acute and inflammatory pain in rats.
Topics: Acute Pain; Analgesics, Opioid; Animals; Chemical and Drug Induced Liver Injury; Diazoxide; Disease | 2013 |
A role for high density lipoproteins in hepatic phosphatidylcholine homeostasis.
Topics: Animals; Apolipoprotein A-I; Chemical and Drug Induced Liver Injury; Choline Deficiency; Female; Gly | 2007 |
Glibenclamide and liver disease.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypogl | 1997 |
Glyburide-induced hepatitis.
Topics: Chemical and Drug Induced Liver Injury; Glyburide; Humans; Male; Middle Aged | 1989 |
Glyburide-induced hepatitis.
Topics: Biopsy; Chemical and Drug Induced Liver Injury; Female; Glyburide; Humans; Liver; Liver Function Tes | 1987 |