glyburide has been researched along with Cardiovascular Stroke in 122 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The objective of this nationwide study was to compare the risk of cardiovascular disease (CVD), all-cause mortality and severe hypoglycemia in patients with type 2 diabetes (T2D) starting second-line treatment with either metformin+sulphonylurea or metformin+dipeptidyl peptidase-4 inhibitor (DPP-4i)." | 7.83 | Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality. ( Bodegard, J; Eriksson, JW; Nathanson, D; Norhammar, A; Nyström, T; Thuresson, M, 2016) |
| "Glyburide is associated with increased cardiovascular mortality and morbidity in patients with diabetes mellitus undergoing emergent percutaneous coronary intervention after myocardial infarction." | 7.77 | Glyburide increases risk in patients with diabetes mellitus after emergent percutaneous intervention for myocardial infarction--a nationwide study. ( Abildstrom, SZ; Bretler, D; Gislason, GH; Hansen, ML; Hansen, PR; Jørgensen, CH; Norgaard, ML; Schramm, TK; Sørensen, R; Torp-Pedersen, C, 2011) |
| "Previous results from our laboratory have suggested that morphine can attenuate neutrophil activation in patients with acute myocardial infarction." | 7.70 | Morphine preconditioning attenuates neutrophil activation in rat models of myocardial infarction. ( Chang, H; Hung, CR; Tseng, YZ; Wang, TL, 1998) |
| "The effect of glibenclamide and glimepiride, two orally active antidiabetic sulphonylurea derivatives, on the development of myocardial infarction has been compared." | 7.70 | Effect of glibenclamide and glimepiride treatment on the development of myocardial infarction in rats. ( Baczkó, I; El-Reyani, NE; Leprán, I; Papp, JG, 2000) |
| " On the other hand, treatment of obese patients with metformin significantly reduced the incidence of myocardial infarction and of mortality diabetes related." | 4.80 | [Should the occurrence of a first coronary event change the management of diabetes?]. ( Dubois-Laforgue, D; Timsit, J, 2000) |
| " The objective of this nationwide study was to compare the risk of cardiovascular disease (CVD), all-cause mortality and severe hypoglycemia in patients with type 2 diabetes (T2D) starting second-line treatment with either metformin+sulphonylurea or metformin+dipeptidyl peptidase-4 inhibitor (DPP-4i)." | 3.83 | Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality. ( Bodegard, J; Eriksson, JW; Nathanson, D; Norhammar, A; Nyström, T; Thuresson, M, 2016) |
| "Using nationwide administrative Danish registries, we followed all individuals without prior stroke or myocardial infarction who initiated metformin and an IS from 1997 through 2009." | 3.81 | Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study. ( Andersson, C; Fosbøl, EL; Gislason, G; Køber, L; Mogensen, UM; Scheller, NM; Schramm, TK; Torp-Pedersen, C; Vaag, A, 2015) |
| "We conducted a population-based cohort study of patients aged 66 years and older who were hospitalized for acute myocardial infarction or who underwent percutaneous coronary intervention between 1 April 2007 and 31 March 2010 while receiving either glyburide or gliclazide." | 3.78 | Adverse cardiovascular events during treatment with glyburide (glibenclamide) or gliclazide in a high-risk population. ( Gomes, T; Juurlink, DN; Mamdani, MM; Shah, BR, 2012) |
| "Glyburide is associated with increased cardiovascular mortality and morbidity in patients with diabetes mellitus undergoing emergent percutaneous coronary intervention after myocardial infarction." | 3.77 | Glyburide increases risk in patients with diabetes mellitus after emergent percutaneous intervention for myocardial infarction--a nationwide study. ( Abildstrom, SZ; Bretler, D; Gislason, GH; Hansen, ML; Hansen, PR; Jørgensen, CH; Norgaard, ML; Schramm, TK; Sørensen, R; Torp-Pedersen, C, 2011) |
| "Polyphenol (-)-epigallocatechin gallate (EGCG), the most abundant catechin of green tea, appears to attenuate myocardial ischemia/reperfusion injury." | 3.76 | Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts. ( Chun, KJ; Jang, Y; Kim, JH; Lee, D; Song, DK; Xu, Z, 2010) |
| "We assessed whether pravastatin attenuates cardiac sympathetic reinnervation after myocardial infarction through the activation of ATP-sensitive K(+) (K(ATP)) channels." | 3.74 | Effect of pravastatin on sympathetic reinnervation in postinfarcted rats. ( Chang, NC; Lee, TM; Lin, MS, 2007) |
| "Male Wistar rats after induction of myocardial infarction were randomized to either vehicle, agonists of K(ATP) channels nicorandil and pinacidil, an antagonist of K(ATP) channels glibenclamide, or a combination of nicorandil and glibenclamide or pinacidil and glibenclamide for 4 weeks." | 3.74 | Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts. ( Chang, NC; Lee, TM; Lin, MS, 2008) |
| "Previous results from our laboratory have suggested that morphine can attenuate neutrophil activation in patients with acute myocardial infarction." | 3.70 | Morphine preconditioning attenuates neutrophil activation in rat models of myocardial infarction. ( Chang, H; Hung, CR; Tseng, YZ; Wang, TL, 1998) |
| "The effect of glibenclamide and glimepiride, two orally active antidiabetic sulphonylurea derivatives, on the development of myocardial infarction has been compared." | 3.70 | Effect of glibenclamide and glimepiride treatment on the development of myocardial infarction in rats. ( Baczkó, I; El-Reyani, NE; Leprán, I; Papp, JG, 2000) |
| " each) to reduce myocardial O2 consumption, and (c) when xylazine was added to pentobarbital anesthesia." | 3.69 | Glibenclamide, a blocker of ATP-sensitive potassium channels, abolishes infarct size limitation by preconditioning in rabbits anesthetized with xylazine/pentobarbital but not with pentobarbital alone. ( Goto, M; Iimura, O; Miki, T; Miura, T; Sakamoto, J; Shimamoto, K, 1995) |
| " We compared the effects of three SU medications and initial SU doses on adverse glycemic and cardiovascular events among NH residents." | 1.91 | Comparative safety of sulfonylureas among U.S. nursing home residents. ( Berry, SD; Hayes, KN; Munshi, MN; Riester, MR; Zullo, AR, 2023) |
| "Metformin was more protective than glyburide for both all-cause (HR: 0." | 1.46 | All-Cause and Cardiovascular Mortality following Treatment with Metformin or Glyburide in Patients with Type 2 Diabetes Mellitus. ( Esteghamati, A; Heidari, B; Larry, M; Mansournia, MA; Nakhjavani, M; Nargesi, AA; Rabizadeh, S; Raee, MR; Zarifkar, M, 2017) |
| "Treatment with pinacidil decreased APD (26%) in co-cultures with sMI-Fb." | 1.39 | Fibroblast KATP currents modulate myocyte electrophysiology in infarcted hearts. ( Benamer, N; Coetzee, WA; Mahoney, VM; Morley, GE; Steinhardt, MJ; Vasquez, C, 2013) |
| " The chronic use of mitochondrial K(ATP) channel agonists after infarction may attenuate the arrhythmogenic response to programmed electrical stimulation." | 1.35 | Effect of ATP-sensitive potassium channel agonists on sympathetic hyperinnervation in postinfarcted rat hearts. ( Chang, NC; Chen, CC; Kang, CS; Lee, TM; Lin, CC, 2009) |
| "There were fewer malignant arrhythmias with PerC during reperfusion (P = 0." | 1.34 | Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning. ( Cheung, M; Dzavik, V; Kharbanda, RK; Konstantinov, IE; Kristiansen, SB; Li, J; Redington, AN; Schmidt, MR; Shimizu, M; Smerup, M; Sorensen, K; White, PA, 2007) |
| "Hypercholesterolemia was induced by two weeks of cholesterol-enriched diet." | 1.31 | K(ATP) channel opening is an endogenous mechanism of protection against the no-reflow phenomenon but its function is compromised by hypercholesterolemia. ( Genda, S; Ichikawa, Y; Miki, T; Miura, T; Shimamoto, K, 2002) |
| "Pretreatment with diazoxide (100 microM) with a 10-min washout period reduced %IS/LV to 7." | 1.31 | Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction. ( Genda, S; Kuno, A; Matsumoto, T; Miki, T; Miura, T; Nozawa, Y; Shimamoto, K; Tanno, M; Tsuchida, A, 2001) |
| "Myocardial infarction was induced by occlusion of the anterior descending coronary artery for 60 min and reperfusion for 270 min." | 1.31 | Mitochondrial ATP dependent potassium channels mediate non-ischemic preconditioning by tachycardia in dogs. ( Domenech, R; Macho, P; Sánchez, G; Schwarze, H; Solis, E, 2001) |
| "Pretreatment with diazoxide (100 microM), a selective mK(ATP) channel opener, for 5 min followed by 10 min washout before the 30-min ischemia and 2-h reperfusion significantly reduced infarct size (9 +/- 3 vs." | 1.31 | Dual roles of mitochondrial K(ATP) channels in diazoxide-mediated protection in isolated rabbit hearts. ( Cone, J; Liu, Y; Wang, S, 2001) |
| "Glimepiride (Glim) is a new sulfonylurea reported to affect nonpancreatic K(ATP) channels less than does Glib." | 1.31 | Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide. ( Baxter, GF; Lawrence, CL; Maddock, HL; Mocanu, MM; Standen, NB; Yellon, DM, 2001) |
| "Treatment with HMR 1098 (10 mg/kg i." | 1.31 | Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion. ( Albus, U; Busch, AE; Englert, HC; Gögelein, H; Ruetten, H, 2001) |
| "Mibefradil is a calcium antagonist with few negative inotropic effects at therapeutic concentrations." | 1.30 | Unique cardioprotective action of the new calcium antagonist mibefradil. ( Backenköhler, U; Dörge, H; Heusch, G; Jalowy, A; Post, H; Schulz, R; Vahlhaus, C, 1999) |
| "Mibefradil is a novel calcium channel blocker with activity at both L-type and T-type calcium channels." | 1.30 | Mibefradil, a T-type and L-type calcium channel blocker, limits infarct size through a glibenclamide-sensitive mechanism. ( Baxter, GF; Gadgil, S; Mocanu, MM; Yellon, DM, 1999) |
| "Myocardial infarction was produced by a 60-minute coronary artery occlusion in open chest pigs." | 1.29 | Rapid ventricular pacing produces myocardial protection by nonischemic activation of KATP+ channels. ( Duncker, DJ; Gho, BC; Koning, MM; Opstal, RL; van Klaarwater, E; Verdouw, PD, 1996) |
| "Adenosine has been proposed to be an important mediator of ischemic preconditioning." | 1.29 | A comparison of adenosine-induced cardioprotection and ischemic preconditioning in dogs. Efficacy, time course, and role of KATP channels. ( Gross, GJ; Yao, Z, 1994) |
| "Pretreatment with glyburide (an ATP-dependent K+ channel blocker) preserved ERP response to SNS (9 +/- 1% shortening of ERP vs." | 1.29 | Transient depression of responses to sympathetic nerve stimulation overlying a subendocardial infarct. ( Cable, DG; Hingtgen, L; Horn, M; Lund, DD; Martins, JB; Rath, TE, 1993) |
| "Acute myocardial infarction was induced by occlusion of the left coronary artery for 1 h followed by reperfusion for 24 h." | 1.29 | Role of endogenous endothelin in the extension of myocardial infarct size studied with the endothelin receptor antagonist, TAK-044. ( Fujino, M; Fujiwara, S; Kojima, M; Kusumoto, K; Watanabe, T, 1995) |
| "In both the stunned myocardium model as well as the infarcted myocardium model, the beneficial effects of the potassium channel openers could not be attributed to differences in the traditional determinants of the extent of ischaemia/reperfusion injury; area at risk size, oxygen consumption, or collateral blood flow." | 1.29 | Cardioprotective actions of potassium channel openers. ( Auchampach, JA; Gross, GJ; Maruyama, M, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (1.64) | 18.7374 |
| 1990's | 55 (45.08) | 18.2507 |
| 2000's | 53 (43.44) | 29.6817 |
| 2010's | 10 (8.20) | 24.3611 |
| 2020's | 2 (1.64) | 2.80 |
| Authors | Studies |
|---|---|
| Zullo, AR | 2 |
| Riester, MR | 2 |
| Hayes, KN | 2 |
| Munshi, MN | 2 |
| Berry, SD | 2 |
| Maslov, LN | 2 |
| Sementsov, AS | 1 |
| Naryzhnaya, NV | 1 |
| Derkachev, IA | 1 |
| Fu, F | 1 |
| Gusakova, SV | 1 |
| Sarybaev, A | 1 |
| Benamer, N | 1 |
| Vasquez, C | 1 |
| Mahoney, VM | 1 |
| Steinhardt, MJ | 1 |
| Coetzee, WA | 1 |
| Morley, GE | 1 |
| Csonka, C | 1 |
| Kupai, K | 1 |
| Bencsik, P | 1 |
| Görbe, A | 1 |
| Pálóczi, J | 1 |
| Zvara, A | 1 |
| Puskás, LG | 1 |
| Csont, T | 1 |
| Ferdinandy, P | 1 |
| Mogensen, UM | 1 |
| Andersson, C | 1 |
| Fosbøl, EL | 1 |
| Schramm, TK | 2 |
| Vaag, A | 1 |
| Scheller, NM | 1 |
| Torp-Pedersen, C | 2 |
| Gislason, G | 1 |
| Køber, L | 1 |
| Eriksson, JW | 1 |
| Bodegard, J | 1 |
| Nathanson, D | 1 |
| Thuresson, M | 1 |
| Nyström, T | 1 |
| Norhammar, A | 1 |
| Raee, MR | 1 |
| Nargesi, AA | 1 |
| Heidari, B | 1 |
| Mansournia, MA | 1 |
| Larry, M | 1 |
| Rabizadeh, S | 1 |
| Zarifkar, M | 1 |
| Esteghamati, A | 1 |
| Nakhjavani, M | 1 |
| Ye, Y | 1 |
| Lin, Y | 1 |
| Perez-Polo, JR | 1 |
| Birnbaum, Y | 2 |
| Zhao, JL | 3 |
| Yang, YJ | 3 |
| Pei, WD | 2 |
| Sun, YH | 2 |
| Zhai, M | 2 |
| Liu, YX | 2 |
| Gao, RL | 3 |
| Argaud, L | 1 |
| Garrier, O | 1 |
| Loufouat, J | 1 |
| Gomez, L | 1 |
| Couture-Lepetit, E | 1 |
| Gateau-Roesch, O | 1 |
| Robert, D | 1 |
| Ovize, M | 3 |
| Kang, CS | 1 |
| Chen, CC | 1 |
| Lin, CC | 1 |
| Chang, NC | 4 |
| Lee, TM | 4 |
| Song, DK | 1 |
| Jang, Y | 1 |
| Kim, JH | 1 |
| Chun, KJ | 1 |
| Lee, D | 1 |
| Xu, Z | 1 |
| Jørgensen, CH | 1 |
| Gislason, GH | 1 |
| Bretler, D | 1 |
| Sørensen, R | 1 |
| Norgaard, ML | 1 |
| Hansen, ML | 1 |
| Abildstrom, SZ | 1 |
| Hansen, PR | 1 |
| Riddle, MC | 1 |
| Kristiansen, SB | 3 |
| Løfgren, B | 2 |
| Nielsen, JM | 1 |
| Støttrup, NB | 2 |
| Buhl, ES | 1 |
| Nielsen-Kudsk, JE | 2 |
| Nielsen, TT | 2 |
| Rungby, J | 1 |
| Flyvbjerg, A | 1 |
| Bøtker, HE | 2 |
| Juurlink, DN | 1 |
| Gomes, T | 1 |
| Shah, BR | 1 |
| Mamdani, MM | 1 |
| Nieszner, E | 1 |
| Posa, I | 1 |
| Kocsis, E | 1 |
| Pogátsa, G | 3 |
| Préda, I | 1 |
| Koltai, MZ | 2 |
| Kupriyanov, VV | 1 |
| Xiang, B | 1 |
| Sun, J | 1 |
| Jilkina, O | 1 |
| Genda, S | 2 |
| Miura, T | 3 |
| Miki, T | 3 |
| Ichikawa, Y | 1 |
| Shimamoto, K | 3 |
| Schulz, R | 3 |
| Gres, P | 1 |
| Heusch, G | 5 |
| Lishmanov, YB | 1 |
| Solenkova, NV | 1 |
| Gross, GJ | 17 |
| Stefano, GB | 1 |
| Tam, SW | 1 |
| Oldenburg, O | 1 |
| Yang, XM | 3 |
| Krieg, T | 2 |
| Garlid, KD | 1 |
| Cohen, MV | 6 |
| Grover, GJ | 3 |
| Downey, JM | 9 |
| Zhu, BM | 1 |
| Miyamoto, S | 1 |
| Nagasawa, Y | 1 |
| Wajima, T | 1 |
| Hashimoto, K | 1 |
| LaDisa, JF | 1 |
| Krolikowski, JG | 1 |
| Pagel, PS | 6 |
| Warltier, DC | 6 |
| Kersten, JR | 6 |
| Maddock, HL | 2 |
| Siedlecka, SM | 1 |
| Yellon, DM | 4 |
| Tavackoli, S | 1 |
| Ashitkov, T | 1 |
| Hu, ZY | 1 |
| Motamedi, M | 1 |
| Uretsky, BF | 1 |
| Proctor, JB | 1 |
| Cui, L | 1 |
| Dong, JH | 1 |
| Zhao, J | 1 |
| Ma, HJ | 1 |
| Guo, SM | 1 |
| He, RR | 1 |
| Raphael, J | 1 |
| Drenger, B | 1 |
| Rivo, J | 1 |
| Berenshtein, E | 1 |
| Chevion, M | 1 |
| Gozal, Y | 1 |
| Flynn, DM | 1 |
| Smith, AH | 1 |
| Treadway, JL | 1 |
| Levy, CB | 1 |
| Soeller, WC | 1 |
| Boettner, WA | 1 |
| Wisniecki, P | 1 |
| Plowchalk, DR | 1 |
| Gernhardt, SS | 1 |
| Tracey, WR | 1 |
| Knight, DR | 1 |
| Chen, JL | 1 |
| Kang, LM | 1 |
| Wu, Y | 1 |
| Lin, MS | 3 |
| Tsai, CH | 1 |
| Schmidt, MR | 1 |
| Smerup, M | 1 |
| Konstantinov, IE | 1 |
| Shimizu, M | 1 |
| Li, J | 1 |
| Cheung, M | 1 |
| White, PA | 1 |
| Sorensen, K | 1 |
| Dzavik, V | 1 |
| Redington, AN | 1 |
| Kharbanda, RK | 1 |
| Strande, JL | 1 |
| Hsu, A | 1 |
| Su, J | 1 |
| Fu, X | 1 |
| Baker, JE | 1 |
| Donato, M | 1 |
| D'Annunzio, V | 1 |
| Berg, G | 1 |
| Gonzalez, G | 1 |
| Schreier, L | 1 |
| Morales, C | 1 |
| Wikinski, RL | 1 |
| Gelpi, RJ | 1 |
| Hu, Y | 1 |
| Chen, X | 1 |
| Pan, TT | 1 |
| Neo, KL | 1 |
| Lee, SW | 1 |
| Khin, ES | 1 |
| Moore, PK | 1 |
| Bian, JS | 1 |
| Zhang, YH | 1 |
| Colantuono, G | 1 |
| Tiravanti, EA | 1 |
| Di Venosa, N | 1 |
| Cazzato, A | 1 |
| Rastaldo, R | 1 |
| Cagiano, R | 1 |
| D'Agostino, D | 1 |
| Federici, A | 1 |
| Fiore, T | 1 |
| Bazargan, M | 1 |
| Faghihi, M | 1 |
| Chitsaz, M | 1 |
| Juan, O | 1 |
| Esteban, E | 1 |
| Sotillo, J | 1 |
| Alberola, V | 1 |
| Kimose, HH | 1 |
| Mozaffari, MS | 1 |
| Schaffer, SW | 1 |
| Lee, SH | 1 |
| Yang, MK | 1 |
| Lim, JH | 1 |
| Seo, HW | 1 |
| Yi, KY | 1 |
| Yoo, SE | 1 |
| Lee, BH | 1 |
| Won, HS | 1 |
| Lee, CS | 1 |
| Choi, WS | 1 |
| Shin, HS | 1 |
| Ji, Y | 1 |
| Pang, QF | 1 |
| Xu, G | 1 |
| Wang, L | 1 |
| Wang, JK | 1 |
| Zeng, YM | 1 |
| D'Alonzo, AJ | 2 |
| Sewter, JC | 1 |
| Darbenzio, RB | 2 |
| Hess, TA | 1 |
| Goto, M | 1 |
| Sakamoto, J | 1 |
| Iimura, O | 1 |
| Billman, GE | 1 |
| Avendano, CE | 1 |
| Halliwill, JR | 1 |
| Burroughs, JM | 1 |
| Post, H | 2 |
| Sakka, S | 1 |
| Wallbridge, DR | 1 |
| Lomuscio, A | 2 |
| Vergani, D | 1 |
| Marano, L | 1 |
| Castagnone, M | 1 |
| Fiorentini, C | 2 |
| Yao, Z | 6 |
| Offstad, J | 1 |
| Kirkebøen, KA | 1 |
| Ilebekk, A | 1 |
| Downing, SE | 1 |
| Walsh, RS | 1 |
| Tsuchida, A | 2 |
| Daly, JJ | 1 |
| Thornton, JD | 2 |
| Auchampach, JA | 5 |
| Maruyama, M | 2 |
| Pieper, GM | 1 |
| Ito, M | 1 |
| Pride, HP | 1 |
| Zipes, DP | 1 |
| Hofmann, D | 1 |
| Opie, LH | 1 |
| Martins, JB | 1 |
| Cable, DG | 1 |
| Rath, TE | 1 |
| Hingtgen, L | 1 |
| Horn, M | 1 |
| Lund, DD | 1 |
| Toombs, CF | 2 |
| Moore, TL | 1 |
| Shebuski, RJ | 1 |
| McGee, DS | 1 |
| Johnston, WE | 1 |
| Vinten-Johansen, J | 2 |
| Thornton, CS | 1 |
| Sterling, DL | 1 |
| Hide, EJ | 2 |
| Ney, P | 1 |
| Piper, J | 2 |
| Thiemermann, C | 2 |
| Vane, JR | 1 |
| Kojima, M | 1 |
| Kusumoto, K | 1 |
| Fujiwara, S | 1 |
| Watanabe, T | 1 |
| Fujino, M | 1 |
| Hess, T | 1 |
| Sleph, PG | 2 |
| Koning, MM | 1 |
| Gho, BC | 1 |
| van Klaarwater, E | 1 |
| Opstal, RL | 1 |
| Duncker, DJ | 1 |
| Verdouw, PD | 1 |
| Leprán, I | 2 |
| Baczkó, I | 2 |
| Varró, A | 1 |
| Papp, JG | 2 |
| Qian, YZ | 2 |
| Levasseur, JE | 1 |
| Yoshida, K | 1 |
| Kukreja, RC | 2 |
| Mizumura, T | 2 |
| Nithipatikom, K | 1 |
| Kitakaze, M | 1 |
| Minamino, T | 1 |
| Node, K | 1 |
| Komamura, K | 1 |
| Shinozaki, Y | 1 |
| Chujo, M | 1 |
| Mori, H | 1 |
| Inoue, M | 1 |
| Hori, M | 1 |
| Kamada, T | 1 |
| Rohmann, S | 1 |
| Fuchs, C | 1 |
| Schelling, P | 2 |
| Elliott, GT | 1 |
| Comerford, ML | 1 |
| Smith, JR | 1 |
| Zhao, L | 1 |
| Mei, DA | 1 |
| Schultz, JE | 1 |
| Cavero, I | 2 |
| Schmeling, TJ | 1 |
| Zhao, ZQ | 1 |
| Todd, JC | 1 |
| Sato, H | 1 |
| Ma, XL | 1 |
| Hoag, JB | 1 |
| Nayeem, MA | 1 |
| D'Angelo, M | 1 |
| Rioufol, G | 1 |
| Loufoua, J | 2 |
| Pop, C | 1 |
| André-Fouät, X | 1 |
| Minaire, Y | 2 |
| Ohno, Y | 1 |
| Minatoguchi, S | 1 |
| Uno, Y | 1 |
| Kariya, T | 1 |
| Arai, M | 1 |
| Yamashita, K | 1 |
| Fujiwara, T | 1 |
| Fujiwara, H | 1 |
| Gysembergh, A | 1 |
| Margonari, H | 1 |
| Ovize, A | 1 |
| André-Fouët, X | 1 |
| Jalowy, A | 1 |
| Backenköhler, U | 1 |
| Dörge, H | 1 |
| Vahlhaus, C | 1 |
| Wang, TL | 1 |
| Chang, H | 1 |
| Hung, CR | 1 |
| Tseng, YZ | 1 |
| Fryer, RM | 1 |
| Hsu, AK | 1 |
| Eells, JT | 1 |
| Nagase, H | 1 |
| Baxter, GF | 3 |
| Mocanu, MM | 2 |
| Gadgil, S | 1 |
| Toller, WG | 3 |
| Hettrick, DA | 1 |
| Lee, YM | 1 |
| Peng, YY | 1 |
| Sheu, JR | 1 |
| Cheng, CY | 1 |
| Yen, MH | 1 |
| Montgomery, MW | 1 |
| Klamann, A | 1 |
| Sarfert, P | 1 |
| Launhardt, V | 1 |
| Schulte, G | 1 |
| Schmiegel, WH | 1 |
| Nauck, MA | 1 |
| Jung, O | 1 |
| Englert, HC | 2 |
| Jung, W | 1 |
| Gögelein, H | 2 |
| Schölkens, BA | 1 |
| Busch, AE | 2 |
| Linz, W | 1 |
| Betteridge, DJ | 1 |
| Close, L | 1 |
| Gumina, RJ | 1 |
| Beier, N | 1 |
| Gross, ER | 2 |
| Pain, T | 1 |
| Critz, SD | 1 |
| Yue, Y | 1 |
| Nakano, A | 1 |
| Liu, GS | 1 |
| Takano, H | 1 |
| Tang, XL | 1 |
| Bolli, R | 1 |
| Gare, M | 1 |
| Wang, S | 1 |
| Cone, J | 1 |
| Liu, Y | 2 |
| El-Reyani, NE | 1 |
| Macho, P | 1 |
| Solis, E | 1 |
| Sánchez, G | 1 |
| Schwarze, H | 1 |
| Domenech, R | 1 |
| Timsit, J | 1 |
| Dubois-Laforgue, D | 1 |
| Jia, DL | 1 |
| Zheng, XW | 1 |
| Qi, GX | 1 |
| Hu, J | 1 |
| Zeng, DY | 1 |
| Müllenheim, J | 1 |
| Frässdorf, J | 1 |
| Preckel, B | 1 |
| Thämer, V | 1 |
| Schlack, W | 1 |
| Lawrence, CL | 1 |
| Standen, NB | 1 |
| Ruetten, H | 1 |
| Albus, U | 1 |
| Kuno, A | 1 |
| Tanno, M | 1 |
| Nozawa, Y | 1 |
| Matsumoto, T | 1 |
| Krenz, M | 1 |
| Baines, CP | 1 |
| Barjot, B | 1 |
| Soler, NG | 1 |
| Bennett, MA | 1 |
| Pentecost, BL | 1 |
| Fitzgerald, MG | 1 |
| Malins, JM | 1 |
| Dzwonczyk, S | 1 |
| Cacciapuoti, F | 1 |
| Spiezia, R | 1 |
| Bianchi, U | 1 |
| Lama, D | 1 |
| D'Avino, M | 1 |
| Varricchio, M | 1 |
| Ballagi-Pordány, G | 1 |
| Köszeghy, A | 1 |
| Aranyi, Z | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of Remote Preconditioning in Primary Percutaneous Intervention of Acute ST Elevation Myocardial Infarction[NCT00435266] | Phase 2/Phase 3 | 250 participants (Anticipated) | Interventional | 2007-02-28 | Completed | ||
| Remote Ischemic Preconditioning in Head and Neck Cancer Reconstruction - A Randomized Controlled Trial[NCT02548377] | 60 participants (Actual) | Interventional | 2015-09-29 | Completed | |||
| Effects on Bleeding in Knee Arthroplasty After Ischemic Preconditioning With Sevoflurane[NCT03379103] | 30 participants (Actual) | Interventional | 2018-02-02 | Completed | |||
| Effect of Intermittent Hypoxia on Ischemia-reperfusion Injury in Healthy Individuals[NCT05423470] | 41 participants (Actual) | Interventional | 2019-05-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for glyburide and Cardiovascular Stroke
| Article | Year |
|---|---|
Potassium channels in the cardiovascular system.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Cardiovascular Physiological Phenomena; Cardi | 1995 |
The warm-up phenomenon and ischaemic preconditioning: an uncertain relationship.
Topics: Animals; Follow-Up Studies; Glyburide; Humans; Ischemic Preconditioning, Myocardial; Myocardial Infa | 1999 |
[Should the occurrence of a first coronary event change the management of diabetes?].
Topics: Acidosis, Lactic; Acute Disease; Adrenergic beta-Antagonists; Blood Glucose; Cardiovascular Agents; | 2000 |
2 trials available for glyburide and Cardiovascular Stroke
| Article | Year |
|---|---|
Effects of glibenclamide on ventricular fibrillation in non-insulin-dependent diabetics with acute myocardial infarction.
Topics: Adult; Aged; Aged, 80 and over; Diabetes Mellitus, Type 2; Female; Glyburide; Humans; Male; Middle A | 1994 |
Effectiveness of glibenclamide on myocardial ischemic ventricular arrhythmias in non-insulin-dependent diabetes mellitus.
Topics: Adult; Angina Pectoris; Blood Glucose; Cardiac Complexes, Premature; Coronary Disease; Diabetes Mell | 1991 |
117 other studies available for glyburide and Cardiovascular Stroke
| Article | Year |
|---|---|
Comparative safety of sulfonylureas among U.S. nursing home residents.
Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur | 2023 |
Comparative safety of sulfonylureas among U.S. nursing home residents.
Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur | 2023 |
Comparative safety of sulfonylureas among U.S. nursing home residents.
Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur | 2023 |
Comparative safety of sulfonylureas among U.S. nursing home residents.
Topics: Aged; Female; Glipizide; Glyburide; Humans; Hypoglycemia; Male; Medicare; Myocardial Infarction; Nur | 2023 |
The Role of Mitochondrial K
Topics: Adenosine Triphosphate; Animals; Glyburide; Hypoxia; KATP Channels; Male; Myocardial Infarction; Rat | 2022 |
Fibroblast KATP currents modulate myocyte electrophysiology in infarcted hearts.
Topics: Action Potentials; Animals; ATP-Binding Cassette Transporters; Fibroblasts; Glyburide; Heart Ventric | 2013 |
Cholesterol-enriched diet inhibits cardioprotection by ATP-sensitive K+ channel activators cromakalim and diazoxide.
Topics: Adenosine Triphosphate; Animals; Cardiotonic Agents; Cholesterol, Dietary; Cromakalim; Decanoic Acid | 2014 |
Metformin in combination with various insulin secretagogues in type 2 diabetes and associated risk of cardiovascular morbidity and mortality--a retrospective nationwide study.
Topics: Aged; Carbamates; Cardiovascular Diseases; Denmark; Diabetes Mellitus, Type 2; Drug Therapy, Combina | 2015 |
Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality.
Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Dipeptidyl-Peptidase IV Inhibitors; Drug Therapy, Co | 2016 |
All-Cause and Cardiovascular Mortality following Treatment with Metformin or Glyburide in Patients with Type 2 Diabetes Mellitus.
Topics: Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Coronary Angiography; Coronary Artery | 2017 |
Oral glyburide, but not glimepiride, blocks the infarct-size limiting effects of pioglitazone.
Topics: Administration, Oral; Animals; Body Weight; Coronary Vessels; Data Interpretation, Statistical; Deca | 2008 |
Carvedilol reduces myocardial no-reflow by decreasing endothelin-1 via activation of the ATP-sensitive K+ channel.
Topics: Animals; Antihypertensive Agents; Carbazoles; Carvedilol; Disease Models, Animal; Endothelin-1; Glyb | 2008 |
Second-generation sulfonylureas preserve inhibition of mitochondrial permeability transition by the mitochondrial K+(ATP) opener nicorandil in experimental myocardial infarction.
Topics: Animals; Calcium; Gliclazide; Glyburide; Hemodynamics; Male; Mitochondria; Myocardial Infarction; Ni | 2009 |
Effect of ATP-sensitive potassium channel agonists on sympathetic hyperinnervation in postinfarcted rat hearts.
Topics: Animals; Arrhythmias, Cardiac; Echocardiography; Endothelin-1; Glyburide; Heart; Hypoglycemic Agents | 2009 |
Polyphenol (-)-epigallocatechin gallate during ischemia limits infarct size via mitochondrial K(ATP) channel activation in isolated rat hearts.
Topics: Animals; Anti-Arrhythmia Agents; Antioxidants; Catechin; Decanoic Acids; Glyburide; Heart; Hemodynam | 2010 |
Glyburide increases risk in patients with diabetes mellitus after emergent percutaneous intervention for myocardial infarction--a nationwide study.
Topics: Aged; Aged, 80 and over; Angioplasty, Balloon, Coronary; Denmark; Diabetes Mellitus; Female; Glyburi | 2011 |
More reasons to say goodbye to glyburide.
Topics: Diabetes Mellitus, Type 2; Glyburide; Humans; Myocardial Infarction | 2010 |
Comparison of two sulfonylureas with high and low myocardial K(ATP) channel affinity on myocardial infarct size and metabolism in a rat model of type 2 diabetes.
Topics: Animals; Diabetes Mellitus, Type 2; Gliclazide; Glyburide; Glycogen; Lactic Acid; Male; Myocardial I | 2011 |
Adverse cardiovascular events during treatment with glyburide (glibenclamide) or gliclazide in a high-risk population.
Topics: Aged; Angioplasty, Balloon, Coronary; Cohort Studies; Diabetes Mellitus, Type 2; Diabetic Angiopathi | 2012 |
Influence of diabetic state and that of different sulfonylureas on the size of myocardial infarction with and without ischemic preconditioning in rabbits.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Glyburide; Hypoglycemic Agents; Isc | 2002 |
The effects of drugs modulating K(+) transport on Rb(+) uptake and distribution in pig hearts following regional ischemia: (87)Rb MRI study.
Topics: Animals; Bumetanide; Glyburide; In Vitro Techniques; Magnetic Resonance Imaging; Myocardial Infarcti | 2002 |
K(ATP) channel opening is an endogenous mechanism of protection against the no-reflow phenomenon but its function is compromised by hypercholesterolemia.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Chronic Disease; Coronary Circulation; Diseas | 2002 |
Activation of ATP-dependent potassium channels is a trigger but not a mediator of ischaemic preconditioning in pigs.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Electrophysiology; Female; Glyburide; Hemodyn | 2003 |
Activation of peripheral delta opioid receptors eliminates cardiac electrical instability in a rat model of post-infarction cardiosclerosis via mitochondrial ATP-dependent K+ channels.
Topics: Adenosine Triphosphate; Analgesics, Opioid; Animals; Decanoic Acids; Disease Models, Animal; Drug An | 2003 |
P1075 opens mitochondrial K(ATP) channels and generates reactive oxygen species resulting in cardioprotection of rabbit hearts.
Topics: Animals; Brain Chemistry; Decanoic Acids; Diazoxide; Glyburide; Guanidines; Hydroxy Acids; Ischemic | 2003 |
Effect of the sarcolemmal K(ATP) channel blocker HMR1098 on arrhythmias induced by programmed electrical stimulation in canine old myocardial infarction model: comparison with glibenclamide.
Topics: Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Benzamides; Disease Models, Animal; Dogs; Ele | 2003 |
Cardioprotection by glucose-insulin-potassium: dependence on KATP channel opening and blood glucose concentration before ischemia.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Cardiotonic Agents; Diabetes Mellitus, Experimental; | 2004 |
Myocardial protection from either ischaemic preconditioning or nicorandil is not blocked by gliclazide.
Topics: Animals; Anti-Arrhythmia Agents; Gliclazide; Glyburide; Hypoglycemic Agents; Ischemic Preconditionin | 2004 |
Simvastatin-induced myocardial protection against ischemia-reperfusion injury is mediated by activation of ATP-sensitive K+ channels.
Topics: Animals; Anti-Arrhythmia Agents; ATP-Binding Cassette Transporters; Collateral Circulation; Disease | 2004 |
Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways.
Topics: Animals; Calcium Channel Blockers; Decanoic Acids; Enzyme Inhibitors; Female; Glyburide; Hemodynamic | 2004 |
High-frequency electrical stimulation of femoral nerve reduces infarct size following myocardial ischemia-reperfusion in rats.
Topics: Animals; Electric Stimulation; Femoral Nerve; Glyburide; Male; Myocardial Infarction; Myocardial Rep | 2004 |
Ischemic preconditioning decreases the reperfusion-related formation of hydroxyl radicals in a rabbit model of regional myocardial ischemia and reperfusion: the role of K(ATP) channels.
Topics: Adenosine Triphosphate; Animals; Chromatography, High Pressure Liquid; Free Radical Scavengers; Glyb | 2005 |
The sulfonylurea glipizide does not inhibit ischemic preconditioning in anesthetized rabbits.
Topics: Animals; Glipizide; Glyburide; Heart; Hypnotics and Sedatives; Hypoglycemic Agents; Insulin; Insulin | 2005 |
Nicorandil reduces myocardial no-reflow by protection of endothelial function via the activation of KATP channel.
Topics: Animals; Antihypertensive Agents; Coronary Circulation; Endothelial Cells; Endothelium, Vascular; Gl | 2006 |
Effects of pravastatin on ventricular remodeling by activation of myocardial KATP channels in infarcted rats: role of 70-kDa S6 kinase.
Topics: Animals; Anticholesteremic Agents; Blotting, Western; Electrophysiology; Glyburide; Heart; Immunohis | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
Intermittent peripheral tissue ischemia during coronary ischemia reduces myocardial infarction through a KATP-dependent mechanism: first demonstration of remote ischemic perconditioning.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Body Temperature; Ele | 2007 |
SCH 79797, a selective PAR1 antagonist, limits myocardial ischemia/reperfusion injury in rat hearts.
Topics: Androstadienes; Animals; Cardiotonic Agents; Disease Models, Animal; Dose-Response Relationship, Dru | 2007 |
Ischemic postconditioning reduces infarct size by activation of A1 receptors and K+(ATP) channels in both normal and hypercholesterolemic rabbits.
Topics: Adenosine A1 Receptor Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Coronary C | 2007 |
Cardioprotection induced by hydrogen sulfide preconditioning involves activation of ERK and PI3K/Akt pathways.
Topics: Animals; Benzophenanthridines; Cardiotonic Agents; Cell Survival; Chromones; Disease Models, Animal; | 2008 |
Effect of pravastatin on sympathetic reinnervation in postinfarcted rats.
Topics: Animals; Blotting, Western; Cardiac Pacing, Artificial; Coronary Vessels; Disease Models, Animal; GA | 2007 |
Intravenous nicorandil preserves endothelial junctions by decreasing endothelin-1 via activation of ATP-sensitive K+ channel.
Topics: Animals; Antigens, CD; Cadherins; Coronary Vessels; Disease Models, Animal; Endothelial Cells; Endot | 2007 |
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Anima | 2008 |
Importance of timing of magnesium administration in the isolated ischemic-reperfused rat heart: role of K(ATP) channels.
Topics: Animals; Cardiotonic Agents; Coronary Circulation; Diazoxide; Drug Administration Schedule; Glyburid | 2008 |
Atrial flutter and myocardial infarction-like ECG changes as manifestations of left ventricle involvement from lung carcinoma.
Topics: Antihypertensive Agents; Antineoplastic Combined Chemotherapy Protocols; Atrial Flutter; Carboplatin | 2008 |
Cardioprotection by L-glutamate during postischaemic reperfusion: reduced infarct size and enhanced glycogen resynthesis in a rat insulin-free heart model.
Topics: Aminooxyacetic Acid; Animals; Enzyme Inhibitors; Glutamic Acid; Glyburide; Glycogen; Hypoglycemic Ag | 2008 |
Effect of ATP-sensitive potassium channel agonists on ventricular remodeling in healed rat infarcts.
Topics: Animals; Glyburide; Hemodynamics; Hypertrophy, Left Ventricular; Immunohistochemistry; KATP Channels | 2008 |
Effect of pressure overload on cardioprotection of mitochondrial KATP channels and GSK-3beta: interaction with the MPT pore.
Topics: Animals; Cardiotonic Agents; Cyclosporine; Diazoxide; Disease Models, Animal; Glyburide; Glycogen Sy | 2008 |
KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury.
Topics: Animals; Aorta; Benzopyrans; Cardiotonic Agents; Decanoic Acids; Disease Models, Animal; Dose-Respon | 2008 |
Exogenous hydrogen sulfide postconditioning protects isolated rat hearts against ischemia-reperfusion injury.
Topics: Animals; Blood Pressure; Buffers; Coronary Circulation; Creatine Kinase; Decanoic Acids; Dose-Respon | 2008 |
Effects of cromakalim or glibenclamide on arrhythmias and dispersion of refractoriness in chronically infarcted in anesthetized dogs.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzopyra | 1995 |
Glibenclamide, a blocker of ATP-sensitive potassium channels, abolishes infarct size limitation by preconditioning in rabbits anesthetized with xylazine/pentobarbital but not with pentobarbital alone.
Topics: Adenosine Triphosphate; Anesthesia; Animals; Blood Glucose; Blood Pressure; Glyburide; Heart Rate; M | 1995 |
The effects of the ATP-dependent potassium channel antagonist, glyburide, on coronary blood flow and susceptibility to ventricular fibrillation in unanesthetized dogs.
Topics: Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Vessels; Dogs; Glyburide; Hemodynami | 1993 |
Intraischemic preconditioning. Increased tolerance to sustained low-flow ischemia by a brief episode of no-flow ischemia without intermittent reperfusion.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Chromatography, High Pressure Liquid; Coronar | 1995 |
The ATP-dependent potassium channel: an endogenous cardioprotective mechanism.
Topics: Acetylcholine; Adenosine; Animals; Anti-Arrhythmia Agents; Coronary Disease; Decanoic Acids; Disease | 1994 |
ATP gated potassium channels in acute myocardial hibernation and reperfusion.
Topics: Adenosine Triphosphate; Animals; Glyburide; Ion Channel Gating; Myocardial Infarction; Myocardial Re | 1994 |
Ketamine-xylazine anaesthesia permits a KATP channel antagonist to attenuate preconditioning in rabbit myocardium.
Topics: Animals; Glyburide; Guanidines; Ketamine; Myocardial Infarction; Myocardial Ischemia; Myocardium; Pi | 1994 |
Cardioprotective actions of potassium channel openers.
Topics: Animals; Benzopyrans; Dihydropyridines; Disease Models, Animal; Dogs; Female; Glyburide; Male; Myoca | 1994 |
The ATP-regulated potassium channel in ischemia-reperfusion injury.
Topics: Adenosine Triphosphate; Animals; Dogs; Glyburide; Ion Channel Gating; Myocardial Contraction; Myocar | 1994 |
Glibenclamide enhances but pinacidil reduces attenuation in sympathetic responsiveness after acute coronary artery occlusion.
Topics: Acute Disease; Animals; Arterial Occlusive Diseases; Coronary Vessels; Denervation; Dogs; Dose-Respo | 1994 |
A comparison of adenosine-induced cardioprotection and ischemic preconditioning in dogs. Efficacy, time course, and role of KATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Decanoic Acids; Dogs; Female; Glyburide; Hydroxy Acids; | 1994 |
Potassium channel blockade and acute myocardial infarction: implications for management of the non-insulin requiring diabetic patient.
Topics: Adenosine Triphosphate; Animals; Coronary Vessels; Diabetes Mellitus, Type 2; Dogs; Glyburide; Guine | 1993 |
An explanation for the reported observation that ATP dependent potassium channel openers mimic preconditioning.
Topics: Adenosine Triphosphate; Animals; Dogs; Glyburide; Ion Channel Gating; Myocardial Infarction; Myocard | 1993 |
Transient depression of responses to sympathetic nerve stimulation overlying a subendocardial infarct.
Topics: Animals; Atropine; Dogs; Electric Stimulation; Endocardium; Evoked Potentials; Glyburide; Myocardial | 1993 |
Acetylcholine mimics ischemic preconditioning via a glibenclamide-sensitive mechanism in dogs.
Topics: Acetylcholine; Animals; Coronary Circulation; Dogs; Female; Glyburide; Male; Myocardial Infarction; | 1993 |
Limitation of infarct size in the rabbit by ischaemic preconditioning is reversible with glibenclamide.
Topics: Animals; Blood Glucose; Female; Glyburide; Male; Myocardial Infarction; Myocardial Ischemia; Myocard | 1993 |
Protection from ischaemic-reperfusion injury with adenosine pretreatment is reversed by inhibition of ATP sensitive potassium channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Disease Models, Animal; Dose-Response Relationship, Drug | 1993 |
Blockade of ATP-sensitive potassium channels increases infarct size but does not prevent preconditioning in rabbit hearts.
Topics: Animals; Female; Glyburide; Guanidines; Male; Myocardial Infarction; Myocardial Ischemia; Pinacidil; | 1993 |
Adenosine A1 receptors, KATP channels, and ischemic preconditioning in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; D | 1993 |
Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Alprostadil; Animals; Anti-Arrhythmia Agents; Biotransformation; Blood Press | 1995 |
Role of endogenous endothelin in the extension of myocardial infarct size studied with the endothelin receptor antagonist, TAK-044.
Topics: Animals; Dogs; Endothelin Receptor Antagonists; Endothelins; Glyburide; Male; Myocardial Infarction; | 1995 |
Endothelin-1-induced reduction of myocardial infarct size by activation of ATP-sensitive potassium channels in a rabbit model of myocardial ischaemia and reperfusion.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Arterial Occlusive Diseases; Blood Pressure | 1995 |
Glyburide-reversible cardioprotective effect of BMS-180448 is independent of action potential shortening.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Female; Glyburide; Guan | 1995 |
Rapid ventricular pacing produces myocardial protection by nonischemic activation of KATP+ channels.
Topics: Animals; Cardiac Pacing, Artificial; Glyburide; Heart Ventricles; Ion Channel Gating; Myocardial Inf | 1996 |
ATP-sensitive potassium channel modulators: both pinacidil and glibenclamide produce antiarrhythmic activity during acute myocardial infarction in conscious rats.
Topics: Adenosine Triphosphate; Animals; Glyburide; Guanidines; Kinetics; Male; Myocardial Infarction; Pinac | 1996 |
KATP channels in rat heart: blockade of ischemic and acetylcholine-mediated preconditioning by glibenclamide.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Glyburide; Heart; Hemodynamics; Myocardial Infarctio | 1996 |
Infarct size-reducing effect of nicorandil is mediated by the KATP channel but not by its nitrate-like properties in dogs.
Topics: Adenosine; Animals; Dogs; Female; Glyburide; Ion Channel Gating; Male; Methylene Blue; Myocardial In | 1996 |
Influence of oral antidiabetic treatment on electrocardiac alterations induced by myocardial infarction.
Topics: Action Potentials; Administration, Oral; Aged; Anti-Arrhythmia Agents; Case-Control Studies; Diabete | 1996 |
Role of activation of ectosolic 5'-nucleotidase in the cardioprotection mediated by opening of K+c channels.
Topics: 5'-Nucleotidase; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Dogs; Enzyme Activation; | 1996 |
In swine myocardium, the infarct size reduction induced by U-89232 is glibenclamide sensitive: evidence that U-89232 is a cardioselective opener of ATP-sensitive potassium channels.
Topics: Animals; Benzopyrans; Coronary Circulation; Coronary Vessels; Glyburide; Guanidines; Heart; Muscle C | 1997 |
Myocardial ischemia/reperfusion protection using monophosphoryl lipid A is abrogated by the ATP-sensitive potassium channel blocker, glibenclamide.
Topics: Adenosine Triphosphate; Adjuvants, Immunologic; Animals; Dose-Response Relationship, Drug; Enzyme-Li | 1996 |
KATP channels and memory of ischemic preconditioning in dogs: synergism between adenosine and KATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Benzopyrans; Coronary Circulation; Dihydropyridines; Dog | 1997 |
Glibenclamide-induced blockade of ischemic preconditioning is time dependent in intact rat heart.
Topics: Animals; Antihypertensive Agents; Blood Glucose; Glyburide; Heart; Hemodynamics; Hypotension; Ischem | 1997 |
Isoflurane mimics ischemic preconditioning via activation of K(ATP) channels: reduction of myocardial infarct size with an acute memory phase.
Topics: Anesthetics, Inhalation; Animals; Coronary Circulation; Dogs; Glyburide; Hemodynamics; Hypoglycemic | 1997 |
Adenosine inhibition of neutrophil damage during reperfusion does not involve K(ATP)-channel activation.
Topics: Adenosine; Adenosine Triphosphate; Animals; Cardiovascular Agents; Cell Adhesion; Creatine Kinase; F | 1997 |
ATP-sensitive potassium channel mediates delayed ischemic protection by heat stress in rabbit heart.
Topics: Animals; Anti-Arrhythmia Agents; Blood Pressure; Decanoic Acids; Glyburide; Heart Rate; Heat Stress | 1997 |
Ventricular fibrillation in preconditioned pig hearts: role of K+ATP channels.
Topics: Action Potentials; Animals; Blood Glucose; Blood Pressure; Glyburide; Heart; Heart Rate; Ischemic Pr | 1997 |
Nicorandil reduces myocardial infarct size by opening the K(ATP) channel in rabbits.
Topics: Analysis of Variance; Animals; Blood Pressure; Dose-Response Relationship, Drug; Glyburide; Heart Ra | 1997 |
Stretch-induced protection shares a common mechanism with ischemic preconditioning in rabbit heart.
Topics: Animals; Coronary Circulation; Elasticity; Glyburide; Heart; Hematocrit; Hemodynamics; Ischemic Prec | 1998 |
Unique cardioprotective action of the new calcium antagonist mibefradil.
Topics: Amlodipine; Animals; Benzimidazoles; Calcium Channel Blockers; Glyburide; Heart; Heart Rate; Heart V | 1999 |
Morphine preconditioning attenuates neutrophil activation in rat models of myocardial infarction.
Topics: Alkaloids; Animals; Benzophenanthridines; Glyburide; Glycopeptides; Hypoglycemic Agents; Intercellul | 1998 |
Opioid-induced second window of cardioprotection: potential role of mitochondrial KATP channels.
Topics: Analgesics; Animals; Benzylidene Compounds; Blood Pressure; Coronary Circulation; Glyburide; Hypogly | 1999 |
ATP-sensitive K+ channels mediate the delayed cardioprotective effect of adenosine A1 receptor activation.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Glucose; Decanoic Acids; Glyburide; H | 1999 |
Mibefradil, a T-type and L-type calcium channel blocker, limits infarct size through a glibenclamide-sensitive mechanism.
Topics: Animals; Benzimidazoles; Calcium Channel Blockers; Disease Progression; Enzyme Activation; Glyburide | 1999 |
Sevoflurane reduces myocardial infarct size and decreases the time threshold for ischemic preconditioning in dogs.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Blood Pressure; Coronary Circulation; Dogs | 1999 |
The effects of a newly synthesized ATP-sensitive potassium channel opener, MJ-355, on blood pressure and myocardial ischemia-reperfusion injury in rats.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Arrhythmias, Cardiac; ATP-Bind | 1999 |
Levosimendan, a new positive inotropic drug, decreases myocardial infarct size via activation of K(ATP) channels.
Topics: Animals; ATP-Binding Cassette Transporters; Cardiotonic Agents; Dogs; Glyburide; Hemodynamics; Hydra | 2000 |
Myocardial infarction in diabetic vs non-diabetic subjects. Survival and infarct size following therapy with sulfonylureas (glibenclamide)
Topics: Aged; Case-Control Studies; Creatine Kinase; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Femal | 2000 |
The K(ATP) channel blocker HMR 1883 does not abolish the benefit of ischemic preconditioning on myocardial infarct mass in anesthetized rabbits.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Blood Glucose; Glyburide; Heart; Ischemic Precon | 2000 |
Diabetes, coronary heart disease and sulphonylureas-not the final word.
Topics: Diabetic Angiopathies; Glyburide; Humans; Hypoglycemic Agents; Myocardial Infarction; Potassium Chan | 2000 |
Inhibitors of ischemic preconditioning do not attenuate Na+/H+ exchange inhibitor mediated cardioprotection.
Topics: Animals; Benzamides; Dogs; Female; Glyburide; Hemodynamics; Hypoglycemic Agents; Ischemic Preconditi | 2000 |
Sarcolemmal and mitochondrial adenosine triphosphate- dependent potassium channels: mechanism of desflurane-induced cardioprotection.
Topics: Adenosine Triphosphate; Anesthetics, Inhalation; Animals; Benzamides; Decanoic Acids; Desflurane; Do | 2000 |
Opening of mitochondrial K(ATP) channels triggers the preconditioned state by generating free radicals.
Topics: Adenosine Triphosphate; Alkaloids; Animals; Benzophenanthridines; Blotting, Western; Decanoic Acids; | 2000 |
Differential role of K(ATP) channels in late preconditioning against myocardial stunning and infarction in rabbits.
Topics: Adenosine Triphosphate; Animals; Decanoic Acids; Diazoxide; Glyburide; Heart; Hemodynamics; Hydroxy | 2000 |
K(ATP) channels mediate the beneficial effects of chronic ethanol ingestion.
Topics: Adenosine Triphosphate; Administration, Oral; Animals; Collateral Circulation; Coronary Circulation; | 2000 |
Dual roles of mitochondrial K(ATP) channels in diazoxide-mediated protection in isolated rabbit hearts.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Diazox | 2001 |
Effect of glibenclamide and glimepiride treatment on the development of myocardial infarction in rats.
Topics: Animals; Coronary Vessels; Glyburide; Heart Ventricles; Hypoglycemic Agents; Image Processing, Compu | 2000 |
Mitochondrial ATP dependent potassium channels mediate non-ischemic preconditioning by tachycardia in dogs.
Topics: Adenosine; Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Decanoic Ac | 2001 |
[Effects of a novel KATP channel opener JTV-506 on myocardial infarct size of isolated rat heart].
Topics: Animals; Chromans; Coronary Circulation; Glyburide; In Vitro Techniques; Male; Myocardial Infarction | 2000 |
Ketamine, but not S(+)-ketamine, blocks ischemic preconditioning in rabbit hearts in vivo.
Topics: Anesthesia; Animals; Glyburide; Heart; Hemodynamics; Ischemic Preconditioning; Ketamine; Male; Myoca | 2001 |
Glimepiride, a novel sulfonylurea, does not abolish myocardial protection afforded by either ischemic preconditioning or diazoxide.
Topics: Animals; Diazoxide; Glyburide; Guanosine Triphosphate; Heart; Heart Ventricles; Hemodynamics; Hypogl | 2001 |
Effects of the cardioselective KATP channel blocker HMR 1098 on cardiac function in isolated perfused working rat hearts and in anesthetized rats during ischemia and reperfusion.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Benzamides; Glyburide; Heart; Hemodynamics; In Vitro Te | 2001 |
Critical timing of mitochondrial K(ATP) channel opening for enhancement of myocardial tolerance against infarction.
Topics: Animals; Anti-Arrhythmia Agents; Coronary Circulation; Decanoic Acids; Diazoxide; Glyburide; Hydroxy | 2001 |
Acute alcohol-induced protection against infarction in rabbit hearts: differences from and similarities to ischemic preconditioning.
Topics: Adenosine Triphosphate; Alcohols; Alkaloids; Analysis of Variance; Animals; Anti-Arrhythmia Agents; | 2001 |
[Oral antidiabetics and the heart: value of glibenclamide].
Topics: Diabetes Complications; Diabetes Mellitus; Glyburide; Heart; Humans; Hypoglycemic Agents; Myocardial | 1977 |
Myocardial infarction in diabetics.
Topics: Administration, Oral; Adult; Aged; Chlorpropamide; Coronary Care Units; Diabetes Complications; Diab | 1975 |
Blockade of ATP-sensitive potassium channels prevents myocardial preconditioning in dogs.
Topics: Adenosine Triphosphate; Animals; Blood Glucose; Coronary Circulation; Coronary Disease; Dogs; Female | 1992 |
Ischemic preconditioning protects against infarction in rat heart.
Topics: Adaptation, Physiological; Adenosine; Animals; Coronary Disease; Glyburide; Heart; In Vitro Techniqu | 1992 |
Pharmacologic profile of cromakalim in the treatment of myocardial ischemia in isolated rat hearts and anesthetized dogs.
Topics: Anesthesia; Animals; Anti-Arrhythmia Agents; Benzopyrans; Blood Pressure; Cardiovascular Agents; Cor | 1990 |
The new K+ channel opener Aprikalim (RP 52891) reduces experimental infarct size in dogs in the absence of hemodynamic changes.
Topics: Animals; Blood Glucose; Coronary Circulation; Coronary Vessels; Dogs; Female; Glyburide; Hemodynamic | 1991 |
Divergent cardiac effects of the first and second generation hypoglycemic sulfonylurea compounds.
Topics: Animals; Arrhythmias, Cardiac; Blood Glucose; Carbutamide; Dose-Response Relationship, Drug; Electro | 1990 |