Page last updated: 2024-10-28

glyburide and Bronchial Hyperreactivity

glyburide has been researched along with Bronchial Hyperreactivity in 5 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Bronchial Hyperreactivity: Tendency of the smooth muscle of the tracheobronchial tree to contract more intensely in response to a given stimulus than it does in the response seen in normal individuals. This condition is present in virtually all symptomatic patients with asthma. The most prominent manifestation of this smooth muscle contraction is a decrease in airway caliber that can be readily measured in the pulmonary function laboratory.

Research Excerpts

ExcerptRelevanceReference
"Treatment with indomethacin reduced IP response in the hyper-reactive model, and did not produce any change in diabetic model with hyper-reactive airways, indicating further disruption of the COX pathway."1.43Deterioration of epithelium mediated mechanisms in diabetic-antigen sensitized airways of guinea pigs. ( Bano, S; Kambadur, M; Mohammad, F; Swati, O, 2016)
"Bimakalim was more potent (pIC50=7."1.31Atypical effect of minoxidil sulphate on guinea pig airways. ( Buchheit, KH; Hofmann, A; Manley, P; Pfannkuche, HJ; Quast, U, 2000)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's3 (60.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Babik, B1
Balogh, AL1
Sudy, R1
Ivankovitsne-Kiss, O1
Fodor, GH1
Petak, F1
Cui, W1
Zhang, S1
Cai, Z1
Hu, X1
Zhang, R1
Wang, Y1
Li, N1
Chen, Z1
Zhang, G1
Bano, S1
Swati, O1
Kambadur, M1
Mohammad, F1
Coelho, FR1
Cavriani, G1
Soares, AL1
Teixeira, SA1
Almeida, PC1
Sudo-Hayashi, LS1
MuscarĂ¡, MN1
Oliveira-Filho, RM1
Vargaftig, BB1
Tavares-de-Lima, W1
Buchheit, KH1
Hofmann, A1
Manley, P1
Pfannkuche, HJ1
Quast, U1

Other Studies

5 other studies available for glyburide and Bronchial Hyperreactivity

ArticleYear
Levosimendan prevents bronchoconstriction and adverse respiratory tissue mechanical changes in rabbits.
    American journal of physiology. Lung cellular and molecular physiology, 2017, Nov-01, Volume: 313, Issue:5

    Topics: Airway Resistance; Animals; Bronchial Hyperreactivity; Bronchoconstriction; Cardiac Output; Disease

2017
The antidiabetic agent glibenclamide protects airway hyperresponsiveness and inflammation in mice.
    Inflammation, 2015, Volume: 38, Issue:2

    Topics: Animals; Bronchial Hyperreactivity; Cells, Cultured; Chickens; Cytokines; Glyburide; Hypoglycemic Ag

2015
Deterioration of epithelium mediated mechanisms in diabetic-antigen sensitized airways of guinea pigs.
    Journal of smooth muscle research = Nihon Heikatsukin Gakkai kikanshi, 2016, Volume: 52, Issue:0

    Topics: Acetylcholine; Animals; Antigens, Bacterial; Bacterial Proteins; Bronchial Hyperreactivity; Bronchoc

2016
Lymphatic-borne IL-1beta and the inducible isoform of nitric oxide synthase trigger the bronchial hyporesponsiveness after intestinal ischema/reperfusion in rats.
    Shock (Augusta, Ga.), 2007, Volume: 28, Issue:6

    Topics: Animals; Bronchial Hyperreactivity; Enzyme Inhibitors; Glyburide; Guanidines; Interleukin-10; Interl

2007
Atypical effect of minoxidil sulphate on guinea pig airways.
    Naunyn-Schmiedeberg's archives of pharmacology, 2000, Volume: 361, Issue:4

    Topics: Adenosine Triphosphate; Animals; Antigen-Antibody Complex; Benzopyrans; Blood Pressure; Bronchial Hy

2000