glyburide has been researched along with Brain Neoplasms in 8 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Brain Neoplasms: Neoplasms of the intracranial components of the central nervous system, including the cerebral hemispheres, basal ganglia, hypothalamus, thalamus, brain stem, and cerebellum. Brain neoplasms are subdivided into primary (originating from brain tissue) and secondary (i.e., metastatic) forms. Primary neoplasms are subdivided into benign and malignant forms. In general, brain tumors may also be classified by age of onset, histologic type, or presenting location in the brain.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Glibenclamide reduced cerebral edema and mortality in a basic study of cerebral ischemia." | 1.91 | Glibenclamide reduces secondary brain injury in a SAH rat model by reducing brain swelling and modulating inflammatory response. ( Igarashi, T; Kajimoto, R; Moro, N; Oshima, H; Otani, N; Suma, T; Yoshino, A, 2023) |
| "Glyburide is a safe, inexpensive, and efficacious alternative to dexamethasone for the treatment of cerebral metastasis-related vasogenic edema." | 1.39 | Inhibition of SUR1 decreases the vascular permeability of cerebral metastases. ( Muldoon, LL; Neuwelt, EA; Pishko, GL; Thompson, EM, 2013) |
| "MS infusion in rats with brain tumors significantly increased transport vesicle density in tumor capillary endothelial and tumor cells." | 1.32 | Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model. ( Black, KL; Ningaraj, NS; Rao, MK, 2003) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (12.50) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Kajimoto, R | 1 |
| Igarashi, T | 1 |
| Moro, N | 1 |
| Oshima, H | 1 |
| Suma, T | 1 |
| Otani, N | 1 |
| Yoshino, A | 1 |
| Kaurav, H | 1 |
| Kapoor, DN | 1 |
| Thompson, EM | 1 |
| Pishko, GL | 1 |
| Muldoon, LL | 1 |
| Neuwelt, EA | 1 |
| Boggs, DH | 1 |
| Simard, JM | 1 |
| Steven, A | 1 |
| Mehta, MP | 1 |
| Banderali, U | 1 |
| Jayanthan, A | 1 |
| Hoeksema, KA | 1 |
| Narendran, A | 1 |
| Giles, WR | 1 |
| Ningaraj, NS | 1 |
| Rao, MK | 1 |
| Black, KL | 1 |
| Thorin, E | 1 |
| Nguyen, TD | 1 |
| Bouthillier, A | 1 |
| Hildick-Smith, M | 1 |
2 reviews available for glyburide and Brain Neoplasms
| Article | Year |
|---|---|
Implantable systems for drug delivery to the brain.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Drug Carriers; Drug Implants; Glyburide; Humans; Ne | 2017 |
Potential of glyburide to reduce intracerebral edema in brain metastases.
Topics: Brain Edema; Brain Neoplasms; Glyburide; Humans; Hypoglycemic Agents; Sulfonylurea Receptors | 2014 |
6 other studies available for glyburide and Brain Neoplasms
| Article | Year |
|---|---|
Glibenclamide reduces secondary brain injury in a SAH rat model by reducing brain swelling and modulating inflammatory response.
Topics: Animals; Brain Edema; Brain Injuries; Brain Neoplasms; Cytokines; Endothelial Cells; Glyburide; Rats | 2023 |
Inhibition of SUR1 decreases the vascular permeability of cerebral metastases.
Topics: Animals; Antimetabolites, Antineoplastic; Brain Neoplasms; Capillary Permeability; Cell Line, Tumor; | 2013 |
Ion channels in pediatric CNS Atypical Teratoid/Rhabdoid Tumor (AT/RT) cells: potential targets for novel therapeutic agents.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Anti-Inflammatory Agents, Non-Steroidal; | 2012 |
Adenosine 5'-triphosphate-sensitive potassium channel-mediated blood-brain tumor barrier permeability increase in a rat brain tumor model.
Topics: Adenosine Triphosphate; Amino Acid Sequence; Animals; Antibodies, Monoclonal; Blood-Brain Barrier; B | 2003 |
Control of vascular tone by endogenous endothelin-1 in human pial arteries.
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Arteries; Brain Neoplasms; Cerebral Cortex; Endothelin | 1998 |
Epilepsy in the elderly.
Topics: Age Factors; Aged; Angiography; Brain Neoplasms; Cerebrovascular Disorders; Dementia; Electroencepha | 1974 |