Page last updated: 2024-10-28

glyburide and Bone Loss, Osteoclastic

glyburide has been researched along with Bone Loss, Osteoclastic in 3 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Research Excerpts

ExcerptRelevanceReference
"Pyroptosis was involved in bone loss induced by occlusal trauma with or without periodontitis, while glyburide reversed inflammation and bone resorption."4.12Study on the role of pyroptosis in bone resorption induced by occlusal trauma with or without periodontitis. ( Jiang, M; Liang, X; Shang, Z; Sun, H; Yin, X; Zhang, T, 2022)
"On day 5, bone resorption was significantly greater in the trauma group compared with the control group or the trauma + glyburide group, and there were significantly higher numbers of osteoclasts and cells positive for IL-1β, NLRP3, and RANKL in the trauma group."1.56Glyburide inhibits the bone resorption induced by traumatic occlusion in rats. ( Arita, S; Arita, Y; Kaneko, T; Kawahara, Y; Nakamura, K; Ohgi, K; Ryu, T; Sakagami, R; Takase, M; Yoshinaga, Y, 2020)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Jiang, M1
Shang, Z1
Zhang, T1
Yin, X1
Liang, X1
Sun, H1
Arita, Y1
Yoshinaga, Y1
Kaneko, T1
Kawahara, Y1
Nakamura, K1
Ohgi, K1
Arita, S1
Ryu, T1
Takase, M1
Sakagami, R1
Zinman, B1
Haffner, SM1
Herman, WH1
Holman, RR1
Lachin, JM1
Kravitz, BG1
Paul, G1
Jones, NP1
Aftring, RP1
Viberti, G1
Kahn, SE1

Trials

1 trial available for glyburide and Bone Loss, Osteoclastic

ArticleYear
Effect of rosiglitazone, metformin, and glyburide on bone biomarkers in patients with type 2 diabetes.
    The Journal of clinical endocrinology and metabolism, 2010, Volume: 95, Issue:1

    Topics: Adult; Aged; Biomarkers; Bone and Bones; Bone Resorption; Diabetes Mellitus, Type 2; Double-Blind Me

2010

Other Studies

2 other studies available for glyburide and Bone Loss, Osteoclastic

ArticleYear
Study on the role of pyroptosis in bone resorption induced by occlusal trauma with or without periodontitis.
    Journal of periodontal research, 2022, Volume: 57, Issue:3

    Topics: Alveolar Bone Loss; Animals; Bone Resorption; Dental Occlusion, Traumatic; Glyburide; Inflammation;

2022
Glyburide inhibits the bone resorption induced by traumatic occlusion in rats.
    Journal of periodontal research, 2020, Volume: 55, Issue:3

    Topics: Animals; Bone Resorption; Dental Occlusion; Glyburide; Inflammasomes; Interleukin-1beta; Male; NLR F

2020