glyburide has been researched along with Blood Poisoning in 7 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We further show, for the first time in any model of sepsis, that glyburide acts as an anti-inflammatory agent by reducing IL1β secretion accompanied by diminished cellular influx and reduced bacterial dissemination to distant organs." | 3.79 | Glyburide reduces bacterial dissemination in a mouse model of melioidosis. ( Bast, A; Breitbach, K; de Jong, HK; Hoogendijk, AJ; Kager, LM; Koh, GC; Krause, K; Peacock, SJ; Steinmetz, I; van der Poll, T; Weehuizen, TA; Wiersinga, WJ, 2013) |
| "Sepsis is a common disease that continues to increase in incidence in the world." | 1.40 | Glibenclamide attenuates myocardial injury by lipopolysaccharides in streptozotocin-induced diabetic mice. ( Cai, J; Deng, YP; Jiang, GJ; Lu, S; Ren, GF; Shen, FM; Yao, Z; Yu, JW; Zhang, LD, 2014) |
| "Glyburide is an oral hypoglycemic agent used to treat diabetes mellitus." | 1.37 | Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis. ( Chaowagul, W; Chierakul, W; Day, NP; Dougan, G; Koh, GC; Lee, SJ; Limmathurotsakul, D; Mahavanakul, W; Maude, RR; Peacock, SJ; Schreiber, MF; van der Poll, T; White, NJ; Wiersinga, WJ; Wuthiekanun, V, 2011) |
| "Sepsis was induced by caecal ligation and puncture (CLP) or sham surgery in Wistar rats." | 1.37 | Early potassium channel blockade improves sepsis-induced organ damage and cardiovascular dysfunction. ( Assreuy, J; Fernandes, D; Heckert, BT; Sordi, R, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 6 (85.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Koh, GC | 2 |
| Weehuizen, TA | 1 |
| Breitbach, K | 1 |
| Krause, K | 1 |
| de Jong, HK | 1 |
| Kager, LM | 1 |
| Hoogendijk, AJ | 1 |
| Bast, A | 1 |
| Peacock, SJ | 2 |
| van der Poll, T | 2 |
| Steinmetz, I | 1 |
| Wiersinga, WJ | 2 |
| Cai, J | 1 |
| Lu, S | 1 |
| Yao, Z | 1 |
| Deng, YP | 1 |
| Zhang, LD | 1 |
| Yu, JW | 1 |
| Ren, GF | 1 |
| Shen, FM | 1 |
| Jiang, GJ | 1 |
| Beck, C | 1 |
| Barthel, F | 1 |
| Hahn, AM | 1 |
| Vollmer, C | 1 |
| Herminghaus, A | 1 |
| Schäfer, S | 1 |
| Bauer, I | 1 |
| Picker, O | 1 |
| Sordi, R | 2 |
| Fernandes, D | 2 |
| Assreuy, J | 2 |
| Maude, RR | 1 |
| Schreiber, MF | 1 |
| Limmathurotsakul, D | 1 |
| Wuthiekanun, V | 1 |
| Lee, SJ | 1 |
| Mahavanakul, W | 1 |
| Chaowagul, W | 1 |
| Chierakul, W | 1 |
| White, NJ | 1 |
| Day, NP | 1 |
| Dougan, G | 1 |
| Heckert, BT | 1 |
| Ismail, JA | 1 |
| McDonough, KH | 1 |
7 other studies available for glyburide and Blood Poisoning
| Article | Year |
|---|---|
Glyburide reduces bacterial dissemination in a mouse model of melioidosis.
Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents; Burkholderia pseudomallei; Ceftazidime; Di | 2013 |
Glibenclamide attenuates myocardial injury by lipopolysaccharides in streptozotocin-induced diabetic mice.
Topics: Animals; Cells, Cultured; Diabetes Mellitus, Experimental; Endotoxemia; Glyburide; Heart Injuries; H | 2014 |
The beneficial effects of acute hypercapnia on microcirculatory oxygenation in an animal model of sepsis are independent of K(+)ATP channels.
Topics: Adenosine Triphosphate; Animals; Colon; Cytokines; Disease Models, Animal; Glyburide; Hemodynamics; | 2015 |
Differential involvement of potassium channel subtypes in early and late sepsis-induced hyporesponsiveness to vasoconstrictors.
Topics: 4-Aminopyridine; Animals; Apamin; Blood Pressure; Female; Glyburide; Muscle Contraction; Muscle, Smo | 2010 |
Glyburide is anti-inflammatory and associated with reduced mortality in melioidosis.
Topics: Adult; Anti-Inflammatory Agents; Burkholderia pseudomallei; Cohort Studies; Female; Glyburide; Human | 2011 |
Early potassium channel blockade improves sepsis-induced organ damage and cardiovascular dysfunction.
Topics: Animals; Blood Pressure; Cardiovascular Diseases; Female; Gene Expression Regulation, Enzymologic; G | 2011 |
The role of K+ATP channels in the control of pre- and post-ischemic left ventricular developed pressure in septic rat hearts.
Topics: Animals; ATP-Binding Cassette Transporters; Blood Pressure; Coronary Circulation; Cromakalim; Escher | 2001 |