glyburide has been researched along with Bile Duct Obstruction in 10 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " We studied the mechanisms involved in the disposition of glyburide and its pharmacologically active hydroxy metabolites M1 and M2b and evaluated their clinical pharmacokinetics and the potential role in glyburide-induced cholestasis employing physiologically based pharmacokinetic (PBPK) modeling." | 1.46 | Transporter-Mediated Disposition, Clinical Pharmacokinetics and Cholestatic Potential of Glyburide and Its Primary Active Metabolites. ( Bi, YA; Li, R; Lin, J; Marroquin, LD; Mathialagan, S; Scialis, RJ; Varma, MVS; Vildhede, A; Yang, X, 2017) |
| "Cholestasis is a cardinal complication of liver disease, but most treatments are merely supportive." | 1.30 | Stimulation of bile duct epithelial secretion by glybenclamide in normal and cholestatic rat liver. ( Burgstahler, AD; Dranoff, JA; Mennone, A; Nathanson, MH; Rios-Velez, L, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (10.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (20.00) | 24.3611 |
| 2020's | 1 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dawson, S | 1 |
| Stahl, S | 1 |
| Paul, N | 1 |
| Barber, J | 1 |
| Kenna, JG | 1 |
| Liu, H | 1 |
| Irobalieva, RN | 1 |
| Kowal, J | 1 |
| Ni, D | 1 |
| Nosol, K | 1 |
| Bang-Sørensen, R | 1 |
| Lancien, L | 1 |
| Stahlberg, H | 1 |
| Stieger, B | 1 |
| Locher, KP | 1 |
| Li, R | 1 |
| Bi, YA | 1 |
| Vildhede, A | 1 |
| Scialis, RJ | 1 |
| Mathialagan, S | 1 |
| Yang, X | 1 |
| Marroquin, LD | 1 |
| Lin, J | 1 |
| Varma, MVS | 1 |
| Nathanson, MH | 1 |
| Burgstahler, AD | 1 |
| Mennone, A | 1 |
| Dranoff, JA | 1 |
| Rios-Velez, L | 1 |
| Ramanathan, M | 1 |
| Wahinuddin, S | 1 |
| Kew, ST | 1 |
| Carratù, R | 1 |
| Parisi, P | 1 |
| Frullone, S | 1 |
| van Basten, JP | 1 |
| van Hoek, B | 1 |
| Zeijen, R | 1 |
| Stockbrügger, R | 1 |
| Del-Val, A | 1 |
| Garrigues, V | 1 |
| Ponce, J | 1 |
| Benages, R | 1 |
| Marriott Díaz, E | 1 |
| Miranda Baiochi, R | 1 |
| Hernández-Guío, C | 1 |
| Clarke, BF | 1 |
| Campbell, IW | 1 |
| Ewing, DJ | 1 |
| Beveridge, GW | 1 |
| MacDonald, MK | 1 |
1 review available for glyburide and Bile Duct Obstruction
| Article | Year |
|---|---|
Glyburide-induced cholestatic hepatitis and liver failure. Case-report and review of the literature.
Topics: Aged; Chemical and Drug Induced Liver Injury; Cholestasis; Female; Glyburide; Humans | 1992 |
9 other studies available for glyburide and Bile Duct Obstruction
| Article | Year |
|---|---|
In vitro inhibition of the bile salt export pump correlates with risk of cholestatic drug-induced liver injury in humans.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters | 2012 |
Structural basis of bile salt extrusion and small-molecule inhibition in human BSEP.
Topics: ATP-Binding Cassette Transporters; Bile Acids and Salts; Cholestasis; Glyburide; Humans; Liver | 2023 |
Transporter-Mediated Disposition, Clinical Pharmacokinetics and Cholestatic Potential of Glyburide and Its Primary Active Metabolites.
Topics: ATP-Binding Cassette Transporters; Bayes Theorem; Biological Transport; Cell Line; Cholestasis; Glyb | 2017 |
Stimulation of bile duct epithelial secretion by glybenclamide in normal and cholestatic rat liver.
Topics: Animals; Bile; Bile Ducts; Biological Transport; Cholestasis; Epithelial Cells; Glyburide; Hypoglyce | 1998 |
Glibenclamide induced chronic cholestasis simulating primary biliary cirrhosis: a case report.
Topics: Adult; Cholestasis; Chronic Disease; Diagnosis, Differential; Female; Glyburide; Humans; Liver Cirrh | 1996 |
Glibenclamide-associated reversible cholestasis.
Topics: Acute Disease; Aged; Aged, 80 and over; Cholestasis; Glyburide; Humans; Liver; Male | 1992 |
Glibenclamide-induced cholestasis.
Topics: Biopsy; Cholestasis; Diabetes Mellitus, Type 2; Glyburide; Humans; Liver; Male; Middle Aged | 1991 |
[Cholestasis from glibenclamide].
Topics: Aged; Aged, 80 and over; Cholestasis; Glyburide; Humans; Male | 1990 |
Generalized hypersensitivity reaction and visceral arteritis with fatal outcome during glibenclamide therapy.
Topics: Acute Kidney Injury; Aged; Arteritis; Autopsy; Bronchopneumonia; Cholestasis; Diabetes Mellitus; Dru | 1974 |