Page last updated: 2024-10-28

glyburide and Asystole

glyburide has been researched along with Asystole in 12 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Research Excerpts

ExcerptRelevanceReference
"The number of FJ-positive degenerating neurons in the CA1 area of the hippocampus, the cerebellum and the thalamic reticular nucleus of the ketogenic diet-fed rats with or without glibenclamide or 5-hydroxydecanoate pre-treatment before cardiac arrest-induced cerebral ischemia is zero."3.75Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration. ( Pham, L; Tai, KK; Truong, DD, 2009)
" GBC was administered as a loading dose of 10 μg/kg intraperitoneally 10 min after the return of spontaneous circulation, followed by a maintenance dosage of 1."1.72The effect of Glibenclamide on somatosensory evoked potentials after cardiac arrest in rats. ( Badjatia, N; Jia, X; Lachance, BB; Wang, Z, 2022)
"Here, in rat model of cardiac arrest with brain edema combined with neuroinflammation, GLB significantly alleviated neurocognitive deficit and neuropathological damage, via the inhibition of microglial NLRP3 inflammasome activation by blocking SUR1-TRPM4."1.72Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia. ( Chang, Y; Chen, J; Gupta, S; He, Y; Huang, K; Ji, Z; Lin, Z; Liu, K; Pan, S; Peng, Y; Wang, S; Wu, Y; Zang, N; Zhu, J, 2022)
"GBC attenuated cerebral edema following CA/CPR by blocking Sur1-TRPM4 channels upregulated by CA insult."1.48Glibenclamide and Therapeutic Hypothermia Have Comparable Effect on Attenuating Global Cerebral Edema Following Experimental Cardiac Arrest. ( Isaka, Y; Nakamura, T; Nakayama, S; Taguchi, N; Tanaka, M, 2018)

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (8.33)18.2507
2000's1 (8.33)29.6817
2010's7 (58.33)24.3611
2020's3 (25.00)2.80

Authors

AuthorsStudies
Lachance, BB2
Wang, Z5
Badjatia, N1
Jia, X3
Zhang, S1
Du, J1
Chen, S1
Polster, BM1
He, Y1
Chang, Y1
Peng, Y1
Zhu, J1
Liu, K1
Chen, J1
Wu, Y2
Ji, Z4
Lin, Z4
Wang, S4
Gupta, S1
Zang, N1
Pan, S4
Huang, K4
Yang, X1
Nakayama, S1
Taguchi, N1
Isaka, Y1
Nakamura, T1
Tanaka, M1
Gu, Y3
Hu, Y2
Li, X2
Xie, Z2
Simard, JM1
Sheth, KN1
Tai, KK1
Pham, L1
Truong, DD1
Taylor, TG1
Venable, PW1
Shibayama, J1
Warren, M1
Zaitsev, AV1
Xie, Y1
Zacharias, E1
Hoff, P1
Tegtmeier, F1

Other Studies

12 other studies available for glyburide and Asystole

ArticleYear
The effect of Glibenclamide on somatosensory evoked potentials after cardiac arrest in rats.
    Neurocritical care, 2022, Volume: 36, Issue:2

    Topics: Animals; Coma; Evoked Potentials, Somatosensory; Glyburide; Heart Arrest; Humans; Male; Rats; Rats,

2022
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
    Translational stroke research, 2023, Volume: 14, Issue:5

    Topics: Animals; Brain Injuries; Glucose; Glyburide; Heart Arrest; Humans; Microglia; Neural Stem Cells; Neu

2023
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
    Molecular neurobiology, 2022, Volume: 59, Issue:10

    Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Glucose; Glyburide; Heart Arrest; Inflammasomes; Mal

2022
Neuroprotection of Glibenclamide against Brain Injury after Cardiac Arrest via Modulation of NLRP3 Inflammasome.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2019, Volume: 2019

    Topics: Animals; Brain Injuries; Cardiopulmonary Resuscitation; Disease Models, Animal; Glyburide; Heart Arr

2019
Glibenclamide and Therapeutic Hypothermia Have Comparable Effect on Attenuating Global Cerebral Edema Following Experimental Cardiac Arrest.
    Neurocritical care, 2018, Volume: 29, Issue:1

    Topics: Animals; Brain Edema; Disease Models, Animal; Glyburide; Heart Arrest; Hypoglycemic Agents; Hypother

2018
Glibenclamide Prevents Water Diffusion Abnormality in the Brain After Cardiac Arrest in Rats.
    Neurocritical care, 2018, Volume: 29, Issue:1

    Topics: Animals; Brain Edema; Diffusion Magnetic Resonance Imaging; Glyburide; Heart Arrest; Male; Neuroprot

2018
Glibenclamide Improves Survival and Neurologic Outcome After Cardiac Arrest in Rats.
    Critical care medicine, 2015, Volume: 43, Issue:9

    Topics: Animals; Brain; Chemokine CCL2; Disease Models, Animal; Glyburide; Heart Arrest; Hemodynamics; Male;

2015
Is Glibenclamide the New Cool in Cardiopulmonary Resuscitation?
    Critical care medicine, 2015, Volume: 43, Issue:9

    Topics: Animals; Glyburide; Heart Arrest; Male; Neuroprotective Agents

2015
Glibenclamide Is Comparable to Target Temperature Management in Improving Survival and Neurological Outcome After Asphyxial Cardiac Arrest in Rats.
    Journal of the American Heart Association, 2016, 07-13, Volume: 5, Issue:7

    Topics: Animals; Asphyxia; Cardiopulmonary Resuscitation; Disease Models, Animal; Glyburide; Heart Arrest; H

2016
Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.
    Brain injury, 2009, Volume: 23, Issue:13-14

    Topics: Animals; Brain Ischemia; Decanoic Acids; Diet, Ketogenic; Fluoresceins; Glyburide; Heart Arrest; Hyd

2009
Role of KATP channel in electrical depression and asystole during long-duration ventricular fibrillation in ex vivo canine heart.
    American journal of physiology. Heart and circulatory physiology, 2012, Jun-01, Volume: 302, Issue:11

    Topics: Animals; Dogs; Electrocardiography; Female; Glyburide; Heart Arrest; KATP Channels; Male; Models, An

2012
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1995, Volume: 15, Issue:4

    Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Calcium; Dizocilpine Maleate; Flunarizine; Glyburid

1995