glyburide has been researched along with Asystole in 12 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The number of FJ-positive degenerating neurons in the CA1 area of the hippocampus, the cerebellum and the thalamic reticular nucleus of the ketogenic diet-fed rats with or without glibenclamide or 5-hydroxydecanoate pre-treatment before cardiac arrest-induced cerebral ischemia is zero." | 3.75 | Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration. ( Pham, L; Tai, KK; Truong, DD, 2009) |
| " GBC was administered as a loading dose of 10 μg/kg intraperitoneally 10 min after the return of spontaneous circulation, followed by a maintenance dosage of 1." | 1.72 | The effect of Glibenclamide on somatosensory evoked potentials after cardiac arrest in rats. ( Badjatia, N; Jia, X; Lachance, BB; Wang, Z, 2022) |
| "Here, in rat model of cardiac arrest with brain edema combined with neuroinflammation, GLB significantly alleviated neurocognitive deficit and neuropathological damage, via the inhibition of microglial NLRP3 inflammasome activation by blocking SUR1-TRPM4." | 1.72 | Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia. ( Chang, Y; Chen, J; Gupta, S; He, Y; Huang, K; Ji, Z; Lin, Z; Liu, K; Pan, S; Peng, Y; Wang, S; Wu, Y; Zang, N; Zhu, J, 2022) |
| "GBC attenuated cerebral edema following CA/CPR by blocking Sur1-TRPM4 channels upregulated by CA insult." | 1.48 | Glibenclamide and Therapeutic Hypothermia Have Comparable Effect on Attenuating Global Cerebral Edema Following Experimental Cardiac Arrest. ( Isaka, Y; Nakamura, T; Nakayama, S; Taguchi, N; Tanaka, M, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (8.33) | 18.2507 |
| 2000's | 1 (8.33) | 29.6817 |
| 2010's | 7 (58.33) | 24.3611 |
| 2020's | 3 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lachance, BB | 2 |
| Wang, Z | 5 |
| Badjatia, N | 1 |
| Jia, X | 3 |
| Zhang, S | 1 |
| Du, J | 1 |
| Chen, S | 1 |
| Polster, BM | 1 |
| He, Y | 1 |
| Chang, Y | 1 |
| Peng, Y | 1 |
| Zhu, J | 1 |
| Liu, K | 1 |
| Chen, J | 1 |
| Wu, Y | 2 |
| Ji, Z | 4 |
| Lin, Z | 4 |
| Wang, S | 4 |
| Gupta, S | 1 |
| Zang, N | 1 |
| Pan, S | 4 |
| Huang, K | 4 |
| Yang, X | 1 |
| Nakayama, S | 1 |
| Taguchi, N | 1 |
| Isaka, Y | 1 |
| Nakamura, T | 1 |
| Tanaka, M | 1 |
| Gu, Y | 3 |
| Hu, Y | 2 |
| Li, X | 2 |
| Xie, Z | 2 |
| Simard, JM | 1 |
| Sheth, KN | 1 |
| Tai, KK | 1 |
| Pham, L | 1 |
| Truong, DD | 1 |
| Taylor, TG | 1 |
| Venable, PW | 1 |
| Shibayama, J | 1 |
| Warren, M | 1 |
| Zaitsev, AV | 1 |
| Xie, Y | 1 |
| Zacharias, E | 1 |
| Hoff, P | 1 |
| Tegtmeier, F | 1 |
12 other studies available for glyburide and Asystole
| Article | Year |
|---|---|
The effect of Glibenclamide on somatosensory evoked potentials after cardiac arrest in rats.
Topics: Animals; Coma; Evoked Potentials, Somatosensory; Glyburide; Heart Arrest; Humans; Male; Rats; Rats, | 2022 |
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
Topics: Animals; Brain Injuries; Glucose; Glyburide; Heart Arrest; Humans; Microglia; Neural Stem Cells; Neu | 2023 |
Glibenclamide Directly Prevents Neuroinflammation by Targeting SUR1-TRPM4-Mediated NLRP3 Inflammasome Activation In Microglia.
Topics: Animals; Anti-Inflammatory Agents; Brain Edema; Glucose; Glyburide; Heart Arrest; Inflammasomes; Mal | 2022 |
Neuroprotection of Glibenclamide against Brain Injury after Cardiac Arrest via Modulation of NLRP3 Inflammasome.
Topics: Animals; Brain Injuries; Cardiopulmonary Resuscitation; Disease Models, Animal; Glyburide; Heart Arr | 2019 |
Glibenclamide and Therapeutic Hypothermia Have Comparable Effect on Attenuating Global Cerebral Edema Following Experimental Cardiac Arrest.
Topics: Animals; Brain Edema; Disease Models, Animal; Glyburide; Heart Arrest; Hypoglycemic Agents; Hypother | 2018 |
Glibenclamide Prevents Water Diffusion Abnormality in the Brain After Cardiac Arrest in Rats.
Topics: Animals; Brain Edema; Diffusion Magnetic Resonance Imaging; Glyburide; Heart Arrest; Male; Neuroprot | 2018 |
Glibenclamide Improves Survival and Neurologic Outcome After Cardiac Arrest in Rats.
Topics: Animals; Brain; Chemokine CCL2; Disease Models, Animal; Glyburide; Heart Arrest; Hemodynamics; Male; | 2015 |
Is Glibenclamide the New Cool in Cardiopulmonary Resuscitation?
Topics: Animals; Glyburide; Heart Arrest; Male; Neuroprotective Agents | 2015 |
Glibenclamide Is Comparable to Target Temperature Management in Improving Survival and Neurological Outcome After Asphyxial Cardiac Arrest in Rats.
Topics: Animals; Asphyxia; Cardiopulmonary Resuscitation; Disease Models, Animal; Glyburide; Heart Arrest; H | 2016 |
Intracisternal administration of glibenclamide or 5-hydroxydecanoate does not reverse the neuroprotective effect of ketogenic diet against ischemic brain injury-induced neurodegeneration.
Topics: Animals; Brain Ischemia; Decanoic Acids; Diet, Ketogenic; Fluoresceins; Glyburide; Heart Arrest; Hyd | 2009 |
Role of KATP channel in electrical depression and asystole during long-duration ventricular fibrillation in ex vivo canine heart.
Topics: Animals; Dogs; Electrocardiography; Female; Glyburide; Heart Arrest; KATP Channels; Male; Models, An | 2012 |
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Calcium; Dizocilpine Maleate; Flunarizine; Glyburid | 1995 |