Page last updated: 2024-10-28

glyburide and Arteriosclerosis, Coronary

glyburide has been researched along with Arteriosclerosis, Coronary in 8 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Research Excerpts

ExcerptRelevanceReference
"Systemic and coronary hemodynamics were assessed in 20 patients before and after K(ATP) channel inhibition with graded intracoronary glibenclamide infusions (4, 16, and 40 microg/min), in an angiographically smooth or mildly stenosed coronary artery following successful elective percutaneous coronary intervention to another vessel."2.70Effect of ATP-sensitive potassium channel inhibition on resting coronary vascular responses in humans. ( Farouque, HM; Meredith, IT; Skyrme-Jones, RA; Worthley, SG; Zhang, MJ, 2002)
"Treatment with glyburide is associated with increased all-cause and cardiovascular mortality in patients with T2DM."1.46All-Cause and Cardiovascular Mortality following Treatment with Metformin or Glyburide in Patients with Type 2 Diabetes Mellitus. ( Esteghamati, A; Heidari, B; Larry, M; Mansournia, MA; Nakhjavani, M; Nargesi, AA; Rabizadeh, S; Raee, MR; Zarifkar, M, 2017)
"Initiating treatment of type 2 diabetes with glibenclamide or glipizide is associated with increased risk of CAD in comparison to gliclazide or glimepiride."1.35Risk of coronary artery disease associated with initial sulphonylurea treatment of patients with type 2 diabetes: a matched case-control study. ( Mogensen, CE; Sadikot, SM, 2008)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's4 (50.00)29.6817
2010's3 (37.50)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Giblett, JP1
Axell, RG1
White, PA1
Clarke, SJ1
McCormick, L1
Read, PA1
Reinhold, J1
Brown, AJ1
O'Sullivan, M1
West, NE1
Dutka, DP1
Hoole, SP1
Zheng, M1
Li, LZ1
Jiang, ZA1
Li, LH1
Feng, YG1
Fu, XH1
Raee, MR1
Nargesi, AA1
Heidari, B1
Mansournia, MA1
Larry, M1
Rabizadeh, S1
Zarifkar, M1
Esteghamati, A1
Nakhjavani, M1
Sadikot, SM1
Mogensen, CE1
Farouque, HM2
Worthley, SG2
Meredith, IT2
Ferreira, BM1
Moffa, PJ1
Falcão, A1
Uchida, A1
Camargo, P1
Pereyra, P1
Soares, PR1
Hueb, W1
Ramires, JA1
O'Brien, RC1
Luo, M1
Skyrme-Jones, RA1
Zhang, MJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Investigation Into Cardioprotective Effect of Glucagon-like Peptide-1 and it's Mechanism of Action During Myocardial Ischaemia[NCT02128022]Phase 132 participants (Actual)Interventional2014-07-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for glyburide and Arteriosclerosis, Coronary

ArticleYear
Glucagon-like peptide-1 derived cardioprotection does not utilize a KATP-channel dependent pathway: mechanistic insights from human supply and demand ischemia studies.
    Cardiovascular diabetology, 2016, Jul-19, Volume: 15

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Coronary Artery Disease; Coronary Vessels; Echocardiogra

2016
Effect of ATP-sensitive potassium channel inhibition on resting coronary vascular responses in humans.
    Circulation research, 2002, Feb-08, Volume: 90, Issue:2

    Topics: Adenosine; Adenosine Triphosphate; Blood Flow Velocity; Blood Glucose; Coronary Angiography; Coronar

2002

Other Studies

6 other studies available for glyburide and Arteriosclerosis, Coronary

ArticleYear
[Effects of different sulfonylureas on the warm-up phenomenon in diabetes patients with coronary artery disease].
    Zhonghua yi xue za zhi, 2017, Jan-17, Volume: 97, Issue:3

    Topics: Angina Pectoris; Coronary Angiography; Coronary Artery Disease; Diabetes Complications; Diabetes Mel

2017
All-Cause and Cardiovascular Mortality following Treatment with Metformin or Glyburide in Patients with Type 2 Diabetes Mellitus.
    Archives of Iranian medicine, 2017, Volume: 20, Issue:3

    Topics: Aged; Cardiovascular Diseases; Cause of Death; Cohort Studies; Coronary Angiography; Coronary Artery

2017
Risk of coronary artery disease associated with initial sulphonylurea treatment of patients with type 2 diabetes: a matched case-control study.
    Diabetes research and clinical practice, 2008, Volume: 82, Issue:3

    Topics: Adult; Case-Control Studies; Coronary Artery Disease; Diabetes Mellitus, Type 2; Diabetic Angiopathi

2008
Effect of ATP-sensitive potassium channel inhibition on coronary metabolic vasodilation in humans.
    Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:5

    Topics: Adenosine Triphosphate; Aged; Angioplasty, Balloon, Coronary; Cardiac Catheterization; Cardiac Pacin

2004
The effects of glibenclamide, a K(ATP) channel blocker, on the warm-up phenomenon.
    Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2005, Volume: 10, Issue:3

    Topics: Analysis of Variance; Angina Pectoris; Chi-Square Distribution; Chronic Disease; Coronary Angiograph

2005
The effects of gliclazide and other sulfonylureas on low-density lipoprotein oxidation in vitro.
    Metabolism: clinical and experimental, 1997, Volume: 46, Issue:12 Suppl 1

    Topics: Administration, Oral; Adult; Antioxidants; Ascorbic Acid; Coronary Artery Disease; Diabetes Mellitus

1997