glyburide has been researched along with Anterior Choroidal Artery Infarction in 8 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Preclinical models of stroke have shown that intravenous glyburide reduces brain swelling and improves survival." | 9.22 | Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial. ( Beslow, LA; Del Zoppo, GJ; Elm, JJ; Hinson, H; Jacobson, S; Kimberly, WT; Molyneaux, BJ; Ostwaldt, AC; Sheth, KN; Simard, JM; Sze, GK, 2016) |
| "Preclinical models of stroke have shown that intravenous glyburide reduces brain swelling and improves survival." | 5.22 | Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial. ( Beslow, LA; Del Zoppo, GJ; Elm, JJ; Hinson, H; Jacobson, S; Kimberly, WT; Molyneaux, BJ; Ostwaldt, AC; Sheth, KN; Simard, JM; Sze, GK, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 3 (37.50) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Vorasayan, P | 1 |
| Bevers, MB | 1 |
| Beslow, LA | 2 |
| Sze, G | 1 |
| Molyneaux, BJ | 2 |
| Hinson, HE | 1 |
| Simard, JM | 4 |
| von Kummer, R | 1 |
| Sheth, KN | 3 |
| Kimberly, WT | 3 |
| Jacobson, SM | 1 |
| MacAllister, TW | 1 |
| Geliebter, DM | 1 |
| King, ZA | 1 |
| Elm, JJ | 1 |
| Hinson, H | 1 |
| Sze, GK | 1 |
| Ostwaldt, AC | 1 |
| Del Zoppo, GJ | 1 |
| Jacobson, S | 1 |
| Yurovsky, V | 1 |
| Tsymbalyuk, N | 1 |
| Melnichenko, L | 1 |
| Ivanova, S | 1 |
| Gerzanich, V | 1 |
| Zhou, Y | 1 |
| Fathali, N | 1 |
| Lekic, T | 1 |
| Tang, J | 1 |
| Zhang, JH | 1 |
| Holstein, A | 1 |
| Lankes, HG | 1 |
| Egberts, EH | 1 |
| Golanov, EV | 1 |
| Christensen, JD | 1 |
| Reis, DJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Randomized, Multi-Center, Prospective, Double Blind, Phase II Trial of RP- 1127 (Glyburide for Injection) in Patients With a Severe Anterior Circulation Ischemic Stroke Who Are Likely to Develop Malignant Edema[NCT01794182] | Phase 2 | 86 participants (Actual) | Interventional | 2013-06-13 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glyburide and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Found in translation: The rationale behind the early development of glibenclamide in large hemispheric infarction.
Topics: Animals; Brain Edema; Cerebral Infarction; Disease Models, Animal; Glyburide; Humans | 2020 |
Profile of intravenous glyburide for the prevention of cerebral edema following large hemispheric infarction: evidence to date.
Topics: Administration, Intravenous; Animals; Aquaporin 4; Brain; Brain Edema; Cerebral Infarction; Evidence | 2018 |
2 trials available for glyburide and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Intravenous Glibenclamide Reduces Lesional Water Uptake in Large Hemispheric Infarction.
Topics: Administration, Intravenous; Aged; Cerebral Infarction; Female; Glyburide; Humans; Male; Middle Aged | 2019 |
Safety and efficacy of intravenous glyburide on brain swelling after large hemispheric infarction (GAMES-RP): a randomised, double-blind, placebo-controlled phase 2 trial.
Topics: Administration, Intravenous; Aged; Brain Edema; Cerebral Infarction; Double-Blind Method; Female; Gl | 2016 |
4 other studies available for glyburide and Anterior Choroidal Artery Infarction
| Article | Year |
|---|---|
Protective effect of delayed treatment with low-dose glibenclamide in three models of ischemic stroke.
Topics: Animals; ATP-Binding Cassette Transporters; Brain; Brain Ischemia; Cerebral Infarction; Data Interpr | 2009 |
Glibenclamide improves neurological function in neonatal hypoxia-ischemia in rats.
Topics: Animals; Animals, Newborn; ATP-Binding Cassette Transporters; Behavior, Animal; Blood Glucose; Brain | 2009 |
[Diagnostic pitfalls in sulfonylurea-induced neuroglycopenic syndrome with hemiparesis, dysphasia and somnolence].
Topics: Aged; Aged, 80 and over; Aphasia; Cerebral Infarction; Consciousness Disorders; Diabetes Mellitus, T | 1998 |
Role of potassium channels in the central neurogenic neuroprotection elicited by cerebellar stimulation in rat.
Topics: Adenosine Triphosphate; Animals; Cerebellar Nuclei; Cerebral Infarction; Cerebral Ventricles; Electr | 1999 |