glyburide has been researched along with Anoxemia in 136 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
Excerpt | Relevance | Reference |
---|---|---|
"In rat carotid artery, levcromakalim produced vasorelaxation mediated by adenosine triphosphate (ATP)-sensitive K(+) channels, whereas hypoxia induced it partly via these channels." | 7.72 | The role of K+ channels in vasorelaxation induced by hypoxia and the modulator effects of lidocaine in the rat carotid artery. ( Dojo, M; Hatano, Y; Iranami, H; Kimoto, Y; Kinoshita, H; Nakahata, K, 2003) |
" The effects of NG-monomethyl-L-arginine, tetrodotoxin and glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial coronary artery rings of the rabbit." | 7.69 | Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. ( Collins, P; Jiang, C, 1994) |
" The effects of phentolamine (5-30 microM) and glibenclamide (10 microM) on action potential characteristics were examined in guinea-pig papillary muscle exposed to either hypoxia or levcromakalim (20 microM)." | 7.68 | Attenuation by phentolamine of hypoxia and levcromakalim-induced abbreviation of the cardiac action potential. ( Boachie-Anash, G; Henderson, CG; Kane, KA; Tweedie, D, 1993) |
"kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 7.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
"In LEVO-pretreated hypoxemia, CO was significantly higher compared to unpretreated hypoxemia." | 5.37 | The effects of levosimendan and glibenclamide on circulatory and metabolic variables in a canine model of acute hypoxia. ( Picker, O; Schober, P; Schwarte, LA; Schwartges, I; Thomas, K, 2011) |
"Desflurane or propofol was applied 10 min before and during 10 min of hypoxia (95% nitrogen, 5% carbon dioxide)." | 5.35 | Effects of desflurane and propofol on electrophysiological parameters during and recovery after hypoxia in rat hippocampal slice CA1 pyramidal cells. ( Cottrell, JE; Kass, IS; Wang, J, 2009) |
"Adenosine dilation was also blunted by glibenclamide, a KATP antagonist (9 +/- 2, 14 +/- 3, 21 +/- 4 vs." | 5.30 | Role of nitric oxide, cyclic nucleotides, and the activation of ATP-sensitive K+ channels in the contribution of adenosine to hypoxia-induced pial artery dilation. ( Armstead, WM, 1997) |
" In arteries with endothelium and contracted with phenylephrine, hypoxia, evoked by exchanging 5% CO2 in air for CO2 in N2, caused a transient contraction followed by a sustained contraction." | 3.73 | Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries. ( Andersen, CU; Laursen, BE; López-Valverde, V; Mulvany, MJ; Simonsen, U, 2005) |
"In rat carotid artery, levcromakalim produced vasorelaxation mediated by adenosine triphosphate (ATP)-sensitive K(+) channels, whereas hypoxia induced it partly via these channels." | 3.72 | The role of K+ channels in vasorelaxation induced by hypoxia and the modulator effects of lidocaine in the rat carotid artery. ( Dojo, M; Hatano, Y; Iranami, H; Kimoto, Y; Kinoshita, H; Nakahata, K, 2003) |
"The K(ATP) channel activator, diazoxide (100 microM, n=6) or hypoxia (0% O2/5% CO2, n=6) significantly attenuated the HR response to 3 Hz SNS by -10+/-4% and -27+/-6% respectively; an effect that was reversed by the K(ATP) channel inhibitor, glibenclamide (30 microM)." | 3.70 | Activation of sulphonylurea-sensitive channels and the NO-cGMP pathway decreases the heart rate response to sympathetic nerve stimulation. ( Mohan, RM; Paterson, DJ, 2000) |
"We investigated whether the adenosine triphosphate (ATP)-sensitive K+ (K(ATP)) channel activation by bimakalim, at concentrations devoid of both negative inotropic and action-potential duration (APD) shortening effects, might exhibit myocardial protection after hypoxia and reoxygenation in human atrial myocardium by using 112 preparations." | 3.70 | Protection of human myocardium in vitro by K(ATP) activation with low concentrations of bimakalim. ( Criniti, A; del Monte, F; Ducouret, P; Iwashiro, K; Monti, F; Papalia, U; Picard, S; Puddu, PE; Rouet, R; Ruvolo, G; Tonelli, E, 1999) |
" In addition, cerebral arteriolar dilation to hypoxia and adenosine is maintained after ischemia despite the expected impairment in K(ATP) function." | 3.70 | Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets. ( Bari, F; Busija, DW; Louis, TM, 1998) |
" The present studies examined the role of adenosine triphosphate-sensitive potassium channels (KATP channels) in modulating the pressor and vasoconstrictor responses to phenylephrine (PE) in conscious instrumented rats 1) during acute hypoxia or 2) after chronic hypoxic exposure." | 3.69 | Glibenclamide does not reverse attenuated vasoreactivity to acute or chronic hypoxia. ( Balderrama, DS; Eichinger, MR; Herrera, GM; Resta, JM; Resta, TC; Richardson, LA; Walker, BR, 1995) |
"We assessed the role of extracellular potassium ([K+]e) on the increase in cerebral blood flow (CBF) during hypoxia, and we tested whether it was affected by glibenclamide or ouabain." | 3.69 | Role of K+ in regulating hypoxic cerebral blood flow in the rat: effect of glibenclamide and ouabain. ( Paterson, DJ; Reid, JM, 1996) |
"The effects of N omega-nitro-L-arginine methyl ester, an inhibitor of nitric oxide synthase; 6-anilino-5,8-quinolinedione (LY83583), an inhibitor of soluble guanylate cyclase; glybenclamide, a ATP-sensitive K+ channel blocking agent; and 5,7-dimethyl-2-ethyl-3-[[2'-(1H-tetrazol-5-yl)-[1,1']-biphenyl-4- yl]methyl]-3H-imidazo[4,5-b]pyridine (L158809), an angiotensin II type I receptor antagonist, on the response to ventilatory hypoxia were investigated in the isolated blood-perfused rat lung." | 3.69 | Influence of N omega-nitro-L-arginine methyl ester, LY83583, glybenclamide and L158809 on pulmonary circulation. ( Cheng, DY; Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD, 1994) |
" The decrease of coronary perfusion pressure induced by hypoxia and by various concentrations of the potassium channel opener levcromakalim was measured and the inhibitory effect of glibenclamide on hypoxic and drug induced vasodilatation was analysed." | 3.69 | The sensitivity of coronary vascular tone to glibenclamide: a study on the isolated perfused guinea pig heart. ( Cyrys, S; Daut, J, 1994) |
" The effects of NG-monomethyl-L-arginine, tetrodotoxin and glibenclamide on hypoxia-induced coronary artery relaxation, induced by bubbling Krebs solution with 95% N2 and 5% CO2 instead of 95% O2 and 5% CO2, were assessed by measuring the changes in isometric tension in isolated epicardial coronary artery rings of the rabbit." | 3.69 | Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide. ( Collins, P; Jiang, C, 1994) |
" Hearts were subjected to 15 min of hypoxia followed by reoxygenation in the presence and in the absence of 100 microns glyburide, an ATP-sensitive potassium channel blocker." | 3.68 | Influence of ATP-sensitive potassium channel blocker on hypoxia-induced damage of isolated guinea pig heart. ( Branz, AJ; McKean, TA, 1992) |
"kg-1 iv 10 min before ischemia or ouabain infusion prevented ventricular fibrillation induced by ischemia in rat and arrhythmias induced by ouabain in guinea pig." | 3.68 | Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig. ( Fu, SX; Li, YS; Yang, XP; Zhang, HL, 1991) |
" The effects of phentolamine (5-30 microM) and glibenclamide (10 microM) on action potential characteristics were examined in guinea-pig papillary muscle exposed to either hypoxia or levcromakalim (20 microM)." | 3.68 | Attenuation by phentolamine of hypoxia and levcromakalim-induced abbreviation of the cardiac action potential. ( Boachie-Anash, G; Henderson, CG; Kane, KA; Tweedie, D, 1993) |
" In order to determine whether activation of adenosine triphosphate (ATP)-sensitive K+ channels exclusively explains the hypoxia- and ischaemia-induced action potential shortening, effects of tolbutamide and glibenclamide on changes in action potential duration (APD) during hypoxia, metabolic blockade or experimental ischaemia were examined in guinea-pig and canine isolated myocardium by standard microelectrode techniques." | 3.68 | Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium. ( Kanno, M; Nakaya, H; Takeda, Y; Tohse, N, 1991) |
"Hydrogen sulfide (H2S) is a gaseous signaling molecule that appears to be involved in numerous biological processes, including regulation of blood pressure and vascular tone." | 1.37 | Hydrogen sulfide and cerebral microvascular tone in newborn pigs. ( Basuroy, S; Fedinec, AL; Jaggar, JH; Leffler, CW; Parfenova, H; Umstot, ES, 2011) |
"When samples were subjected to strong hypoxemia using 95% N(2)/5% CO(2), these parameters became even more sensitive to the drug." | 1.37 | Glibenclamide reduces proinflammatory cytokines in an ex vivo model of human endotoxinaemia under hypoxaemic conditions. ( Chiba, P; Moravcevic, I; Möslinger, T; Schmid, D; Sorgner, A; Svoboda, M; Thalhammer, T, 2011) |
"In LEVO-pretreated hypoxemia, CO was significantly higher compared to unpretreated hypoxemia." | 1.37 | The effects of levosimendan and glibenclamide on circulatory and metabolic variables in a canine model of acute hypoxia. ( Picker, O; Schober, P; Schwarte, LA; Schwartges, I; Thomas, K, 2011) |
"In fact, severe ischemia reperfusion injury can significantly reduce graft survival, even with modern immunosuppressive agents." | 1.35 | Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia. ( Chilton, L; Figura, M; Giles, WR; Knight, D; Kubes, P; Liacini, A; Millar, TM; Patel, K; Phan, V; Tibbles, LA; Viskovic, MM, 2009) |
"During anoxia, [Ca(2+)](c) increased 9." | 1.35 | Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle. ( Buck, LT; Cooray, M; Pamenter, ME; Shin, DS, 2008) |
"Desflurane or propofol was applied 10 min before and during 10 min of hypoxia (95% nitrogen, 5% carbon dioxide)." | 1.35 | Effects of desflurane and propofol on electrophysiological parameters during and recovery after hypoxia in rat hippocampal slice CA1 pyramidal cells. ( Cottrell, JE; Kass, IS; Wang, J, 2009) |
"Pretreatment with cromakalim, an opener of K(ATP) channels, occluded the hypoxia-induced hyperpolarization." | 1.32 | Effect of acute hypoxia on ATP-sensitive potassium currents in substantia gelatinosa neurons of juvenile rats. ( Jung, SJ; Kim, J; Kwak, J; Lim, W; Park, YK; Yoo, JE, 2003) |
"Diazoxide was without effect on tau(open) and tau(closed,fast) but decreased significantly tau(closed,slow) (24." | 1.31 | Analysis of single K(ATP) channels in mammalian dentate gyrus granule cells. ( Carlen, PL; Pahapill, PA; Pelletier, MR; Pennefather, PS, 2000) |
"During tissue anoxia, elicited by superfusion of N(2)-gassed solution, the biphasic response of the respiratory activity was accompanied by a continuous rise in the IOS." | 1.31 | Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress. ( Haller, M; Mironov, SL; Richter, DW, 2001) |
"Over a 1-h period of anoxia, 59% of Tr cells and 85% Sed cells expressed I(K(ATP))." | 1.31 | Exercise training alters an anoxia-induced, glibenclamide-sensitive current in rat ventricular cardiocytes. ( Jew, KN; Moore, RL, 2002) |
"Adenosine dilation was also blunted by glibenclamide, a KATP antagonist (9 +/- 2, 14 +/- 3, 21 +/- 4 vs." | 1.30 | Role of nitric oxide, cyclic nucleotides, and the activation of ATP-sensitive K+ channels in the contribution of adenosine to hypoxia-induced pial artery dilation. ( Armstead, WM, 1997) |
"Exposure to anoxia has been reported to activate ATP-sensitive potassium (K+(ATP)) channels in isolated ventricular myocytes." | 1.30 | Anoxia-induced activation of ATP-sensitive K+ channels in guinea pig ventricular cells and its modulation by glycolysis. ( Arita, M; Shigematsu, S, 1997) |
"Cromakalim dilation also was not associated with increased CSF cGMP and was unchanged by the Rp diastereomer of 8-bromoguanosine 3',5'-cyclic monophosphothioate, a cGMP antagonist." | 1.30 | Relationship among NO, the KATP channel, and opioids in hypoxic pial artery dilation. ( Armstead, WM, 1998) |
"The suppression during anoxia (PO2 = 0 mmHg) was approximately 35% (voltage step from -60 to +30 mV) and was due to a combination of several factors: (i) suppression of a cadmium-sensitive, Ca2+-dependent K+ current, IK(CaO2); (ii) suppression of a Ca2+-insensitive, delayed rectifier type K+ current, IK(VO2); (iii) activation of a glibenclamide- (and Ca2+)-sensitive current, IK(ATP)." | 1.30 | Anoxia differentially modulates multiple K+ currents and depolarizes neonatal rat adrenal chromaffin cells. ( Nurse, CA; Thompson, RJ, 1998) |
"Glibenclamide increased the number of arrhythmias in the normoxic hearts from 1316+/-215 to 2091+/-187 (by 59%) and in the hypoxic group from 636+/-103 to 1777+/-186 (by 179%)." | 1.30 | Adaptation to high altitude hypoxia protects the rat heart against ischemia-induced arrhythmias. Involvement of mitochondrial K(ATP) channel. ( Asemu, G; Kolár, F; Ostádal, B; Papousek, F, 1999) |
"Acute anoxia or severe hypoxia causes an initial transient contraction followed by marked relaxation of vascular tissues." | 1.29 | Critical role of endothelium in sustained arterial contraction during prolonged hypoxia. ( Mehta, JL; Yang, BC, 1995) |
"After approximately 8 min anoxia, the KATP current started to rise and reached a maximum of 21." | 1.29 | Simultaneous recording of ATP-sensitive K+ current and intracellular Ca2+ in anoxic rat ventricular myocytes. Effects of glibenclamide. ( Englert, H; Gögelein, H; Russ, U; Schölkens, BA, 1996) |
"1 ml), and dose-response curves to levcromakalim (a KATP channel opener) or isoproterenol were constructed." | 1.29 | Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro. ( Croxton, TL; Fernandes, LB; Hirshman, CA; Lindeman, KS, 1994) |
"3." | 1.28 | Opposing actions of tolbutamide and glibenclamide on hypoxic pulmonary vasoconstriction. ( Kozlowski, RZ; Nye, PC; Robertson, BE, 1992) |
"2." | 1.28 | Anoxia induces time-independent K+ current through KATP channels in isolated heart cells of the guinea-pig. ( Benndorf, K; Bollmann, G; Friedrich, M; Hirche, H, 1992) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 2 (1.47) | 18.7374 |
1990's | 84 (61.76) | 18.2507 |
2000's | 32 (23.53) | 29.6817 |
2010's | 17 (12.50) | 24.3611 |
2020's | 1 (0.74) | 2.80 |
Authors | Studies |
---|---|
Maslov, LN | 1 |
Sementsov, AS | 1 |
Naryzhnaya, NV | 1 |
Derkachev, IA | 1 |
Fu, F | 1 |
Gusakova, SV | 1 |
Sarybaev, A | 1 |
Lebreton, F | 1 |
Berishvili, E | 1 |
Parnaud, G | 1 |
Rouget, C | 1 |
Bosco, D | 1 |
Berney, T | 1 |
Lavallard, V | 1 |
Fukuda, M | 1 |
Ando, N | 1 |
Sugasawa, Y | 1 |
Inoue, R | 1 |
Nakauchi, S | 1 |
Miura, M | 2 |
Nishimura, K | 1 |
Yu, L | 1 |
Li, W | 1 |
Park, BM | 1 |
Lee, GJ | 1 |
Kim, SH | 1 |
Levin, SG | 1 |
Shamsutdinova, AA | 1 |
Godukhin, OV | 1 |
Yuan, F | 2 |
Li, HW | 1 |
Song, SJ | 1 |
Teng, X | 1 |
Ma, HJ | 2 |
Guo, Z | 1 |
Zhang, Y | 4 |
Zhou, ZN | 4 |
Vollmer, C | 1 |
Weiß, S | 1 |
Beck, C | 1 |
Bauer, I | 1 |
Picker, O | 2 |
Ma, YC | 1 |
Wang, SJ | 1 |
Chen, HE | 1 |
Huang, LJ | 1 |
He, JB | 1 |
Wang, Y | 1 |
Wang, WT | 1 |
Bu, HM | 1 |
Yang, CY | 1 |
Wang, ML | 1 |
Sun, H | 1 |
Wang, D | 1 |
Liu, Y | 3 |
Lu, P | 1 |
Zhu, D | 1 |
Zhu, Y | 1 |
Simard, JM | 1 |
Geng, Z | 1 |
Woo, SK | 1 |
Ivanova, S | 1 |
Tosun, C | 1 |
Melnichenko, L | 1 |
Gerzanich, V | 1 |
Wang, J | 1 |
Cottrell, JE | 1 |
Kass, IS | 1 |
Figura, M | 1 |
Chilton, L | 1 |
Liacini, A | 1 |
Viskovic, MM | 1 |
Phan, V | 1 |
Knight, D | 1 |
Millar, TM | 1 |
Patel, K | 1 |
Kubes, P | 1 |
Giles, WR | 1 |
Tibbles, LA | 1 |
Paddenberg, R | 1 |
Faulhammer, P | 1 |
Goldenberg, A | 1 |
Gries, B | 1 |
Heinl, J | 1 |
Kummer, W | 1 |
Leffler, CW | 1 |
Parfenova, H | 1 |
Basuroy, S | 1 |
Jaggar, JH | 1 |
Umstot, ES | 1 |
Fedinec, AL | 1 |
Schwarte, LA | 1 |
Schwartges, I | 1 |
Thomas, K | 1 |
Schober, P | 1 |
Jackson-Weaver, O | 1 |
Paredes, DA | 1 |
Gonzalez Bosc, LV | 1 |
Walker, BR | 2 |
Kanagy, NL | 1 |
Lin, YK | 1 |
Lai, MS | 1 |
Chen, YC | 1 |
Cheng, CC | 1 |
Huang, JH | 1 |
Chen, SA | 1 |
Chen, YJ | 1 |
Lin, CI | 1 |
Schmid, D | 1 |
Svoboda, M | 1 |
Sorgner, A | 1 |
Moravcevic, I | 1 |
Thalhammer, T | 1 |
Chiba, P | 1 |
Möslinger, T | 1 |
Nakaizumi, A | 1 |
Puro, DG | 1 |
Gao, L | 2 |
Guan, Y | 1 |
Cui, F | 2 |
Liu, YX | 1 |
Dong, ZF | 1 |
Kline, DD | 1 |
Li, DP | 1 |
Weintraub, NL | 1 |
Miura, H | 1 |
Wachtel, RE | 1 |
Loberiza, FR | 1 |
Saito, T | 1 |
Nicolosi, AC | 1 |
Gutterman, DD | 1 |
Park, YK | 1 |
Jung, SJ | 1 |
Yoo, JE | 1 |
Kwak, J | 1 |
Lim, W | 1 |
Kim, J | 1 |
Zhu, HF | 1 |
Dong, JW | 1 |
Zhu, WZ | 1 |
Ding, HL | 1 |
Kinoshita, H | 2 |
Kimoto, Y | 1 |
Nakahata, K | 1 |
Iranami, H | 1 |
Dojo, M | 1 |
Hatano, Y | 1 |
Bruce, J | 1 |
Taggart, M | 1 |
Austin, C | 1 |
Milano, G | 1 |
Bianciardi, P | 1 |
Corno, AF | 1 |
Raddatz, E | 1 |
Morel, S | 1 |
von Segesser, LK | 1 |
Samaja, M | 1 |
Mo, FM | 1 |
Ballard, HJ | 1 |
Chen, J | 1 |
Zhu, JX | 1 |
Wilson, I | 1 |
Cameron, JS | 1 |
López-Valverde, V | 1 |
Andersen, CU | 1 |
Laursen, BE | 1 |
Mulvany, MJ | 1 |
Simonsen, U | 1 |
Park, WS | 1 |
Son, YK | 1 |
Kim, N | 1 |
Ko, JH | 1 |
Kang, SH | 1 |
Warda, M | 1 |
Earm, YE | 1 |
Jung, ID | 1 |
Park, YM | 1 |
Han, J | 1 |
Colantuono, G | 1 |
Tiravanti, EA | 1 |
Di Venosa, N | 1 |
Cazzato, A | 1 |
Rastaldo, R | 1 |
Cagiano, R | 1 |
D'Agostino, D | 1 |
Federici, A | 1 |
Fiore, T | 1 |
Pamenter, ME | 1 |
Shin, DS | 1 |
Cooray, M | 1 |
Buck, LT | 1 |
Yang, BC | 1 |
Mehta, JL | 1 |
Taguchi, H | 2 |
Faraci, FM | 2 |
Kitazono, T | 2 |
Heistad, DD | 2 |
Xie, Y | 1 |
Zacharias, E | 1 |
Hoff, P | 1 |
Tegtmeier, F | 1 |
Reid, JM | 2 |
Davies, AG | 1 |
Ashcroft, FM | 1 |
Paterson, DJ | 3 |
Shankar, V | 1 |
Armstead, WM | 3 |
Mellemkjaer, S | 2 |
Nielsen-Kudsk, JE | 2 |
Decking, UK | 1 |
Reffelmann, T | 2 |
Schrader, J | 1 |
Kammermeier, H | 2 |
Sawanobori, T | 1 |
Adaniya, H | 1 |
Yukisada, H | 1 |
Hiraoka, M | 1 |
Savineau, JP | 1 |
Gonzalez de la Fuente, P | 1 |
Marthan, R | 1 |
Feng, CJ | 1 |
Cheng, DY | 1 |
Kaye, AD | 1 |
Kadowitz, PJ | 1 |
Nossaman, BD | 1 |
Hara, A | 1 |
Abiko, Y | 1 |
Cyrys, S | 1 |
Daut, J | 2 |
Froldi, G | 1 |
Pandolfo, L | 1 |
Chinellato, A | 1 |
Ragazzi, E | 1 |
Caparrotta, L | 1 |
Fassina, G | 1 |
Reeves, WB | 1 |
Shah, SV | 1 |
Jiang, C | 2 |
Collins, P | 1 |
Fredricks, KT | 2 |
Rusch, NJ | 3 |
Lombard, JH | 3 |
Marshall, JM | 3 |
Thomas, T | 1 |
Turner, L | 1 |
Loutzenhiser, RD | 1 |
Parker, MJ | 1 |
Lindeman, KS | 1 |
Fernandes, LB | 2 |
Croxton, TL | 1 |
Hirshman, CA | 1 |
Oka, M | 1 |
Morris, KG | 2 |
McMurtry, IF | 4 |
Hong, SJ | 1 |
Chang, CC | 1 |
Wong, J | 1 |
Vanderford, PA | 1 |
Fineman, JR | 1 |
Chang, R | 1 |
Soifer, SJ | 1 |
Greenberg, B | 1 |
Kishiyama, S | 1 |
MacKenzie, I | 1 |
Saville, VL | 1 |
Waterfall, JF | 1 |
Eddahibi, S | 1 |
Springall, D | 1 |
Mannan, M | 1 |
Carville, C | 1 |
Chabrier, PE | 1 |
Levame, M | 1 |
Raffestin, B | 1 |
Polak, J | 1 |
Adnot, S | 1 |
Tweedie, D | 1 |
Boachie-Anash, G | 1 |
Henderson, CG | 1 |
Kane, KA | 1 |
Smirnov, SV | 1 |
Robertson, TP | 1 |
Ward, JP | 1 |
Aaronson, PI | 1 |
Takata, Y | 1 |
Shimada, F | 1 |
Kato, H | 1 |
Kalsner, S | 1 |
Eichinger, MR | 1 |
Resta, TC | 1 |
Balderrama, DS | 1 |
Herrera, GM | 1 |
Richardson, LA | 1 |
Resta, JM | 1 |
Yabe, K | 1 |
Nasa, Y | 1 |
Takeo, S | 2 |
Russ, U | 1 |
Englert, H | 1 |
Schölkens, BA | 1 |
Gögelein, H | 1 |
Cornfield, DN | 1 |
Reeve, HL | 1 |
Tolarova, S | 1 |
Weir, EK | 1 |
Archer, S | 2 |
Vallet, B | 1 |
Guery, B | 1 |
Mangalaboyi, J | 1 |
Menager, P | 1 |
Curtis, SE | 1 |
Cain, SM | 1 |
Chopin, C | 1 |
Dupuis, BA | 1 |
Wanstall, JC | 1 |
O'Brien, E | 1 |
Pierrefiche, O | 1 |
Bischoff, AM | 1 |
Richter, DW | 3 |
Shigemori, K | 1 |
Ishizaki, T | 1 |
Matsukawa, S | 1 |
Sakai, A | 1 |
Nakai, T | 1 |
Miyabo, S | 1 |
Wu, CW | 1 |
Leung, CK | 1 |
Yung, WH | 1 |
Hüsken, BC | 1 |
Pfaffendorf, M | 1 |
van Zwieten, PA | 1 |
Baker, JE | 4 |
Curry, BD | 1 |
Olinger, GN | 1 |
Gross, GJ | 4 |
Gauthier-Rein, KM | 1 |
Bizub, DM | 2 |
Contney, SJ | 2 |
Bosnjak, ZJ | 2 |
Boels, PJ | 1 |
Gao, B | 1 |
Deutsch, J | 1 |
Haworth, SG | 2 |
Shivkumar, K | 1 |
Deutsch, NA | 1 |
Lamp, ST | 2 |
Khuu, K | 1 |
Goldhaber, JI | 1 |
Weiss, JN | 2 |
Shigematsu, S | 1 |
Arita, M | 1 |
Bari, F | 1 |
Louis, TM | 1 |
Busija, DW | 1 |
Mironov, SL | 2 |
Langohr, K | 1 |
Haller, M | 2 |
Van Lunteren, E | 1 |
Moyer, M | 1 |
Torres, A | 1 |
Barman, SA | 1 |
Evans, AM | 1 |
Osipenko, ON | 1 |
Gurney, AM | 1 |
Jovanovic, A | 1 |
Jovanovic, S | 1 |
Carrasco, AJ | 1 |
Terzic, A | 1 |
Thompson, RJ | 1 |
Nurse, CA | 1 |
Bryan, PT | 1 |
Pék-Scott, M | 1 |
Lutz, PL | 1 |
Roman, RJ | 1 |
Golanov, EV | 1 |
Reis, DJ | 1 |
Dumas, JP | 1 |
Goirand, F | 2 |
Bardou, M | 2 |
Dumas, M | 2 |
Rochette, L | 2 |
Advenier, C | 1 |
Giudicelli, JF | 1 |
Picard, S | 1 |
Criniti, A | 1 |
Iwashiro, K | 1 |
Rouet, R | 1 |
Monti, F | 1 |
Tonelli, E | 1 |
Ruvolo, G | 1 |
Ducouret, P | 1 |
del Monte, F | 1 |
Papalia, U | 1 |
Puddu, PE | 1 |
Tomiyama, Y | 1 |
Brian, JE | 1 |
Todd, MM | 1 |
Fukuda, S | 1 |
Toriumi, T | 1 |
Xu, H | 1 |
Nishimaki, H | 1 |
Kokubun, S | 1 |
Fujiwara, N | 1 |
Fujihara, H | 1 |
Shimoji, K | 1 |
Tanonaka, K | 1 |
Taguchi, T | 1 |
Koshimizu, M | 1 |
Ando, T | 1 |
Morinaka, T | 1 |
Yogo, T | 1 |
Konishi, F | 1 |
Asemu, G | 1 |
Papousek, F | 1 |
Ostádal, B | 1 |
Kolár, F | 1 |
Sato, K | 1 |
Morio, Y | 1 |
Rodman, DM | 3 |
Mohan, RM | 1 |
Michelakis, E | 1 |
Rebeyka, I | 1 |
Bateson, J | 1 |
Olley, P | 1 |
Puttagunta, L | 1 |
Pelletier, MR | 1 |
Pahapill, PA | 1 |
Pennefather, PS | 1 |
Carlen, PL | 1 |
Eells, JT | 1 |
Henry, MM | 1 |
Singh, R | 1 |
Kalyanaraman, B | 1 |
Dumas, J | 1 |
Ambalavanan, N | 1 |
Bulger, A | 1 |
Ware, J | 1 |
Philips, J | 1 |
Skobel, EC | 1 |
Hanrath, P | 1 |
Schwarz, ER | 1 |
Smani, T | 1 |
Hernández, A | 1 |
Ureña, J | 1 |
Castellano, AG | 1 |
Franco-Obregón, A | 1 |
Ordoñez, A | 1 |
López-Barneo, J | 1 |
Bartlett, IS | 1 |
Kerkhof, CJ | 1 |
Van Der Linden, PJ | 1 |
Sipkema, P | 1 |
Jew, KN | 1 |
Moore, RL | 1 |
MacCormack, TJ | 1 |
Driedzic, WR | 1 |
Robertson, BE | 1 |
Kozlowski, RZ | 1 |
Nye, PC | 1 |
McKean, TA | 1 |
Branz, AJ | 1 |
Benndorf, K | 1 |
Bollmann, G | 1 |
Friedrich, M | 1 |
Hirche, H | 1 |
Spina, D | 1 |
Preuss, JM | 1 |
Hay, DW | 1 |
Muccitelli, RM | 1 |
Page, CP | 1 |
Goldie, RG | 1 |
Trezise, DJ | 1 |
Weston, AH | 1 |
Zhang, HL | 1 |
Li, YS | 1 |
Fu, SX | 1 |
Yang, XP | 1 |
Hasunuma, K | 2 |
Yamaguchi, T | 1 |
O'Brien, RF | 1 |
Carmeliet, E | 1 |
Wiener, CM | 1 |
Dunn, A | 1 |
Sylvester, JT | 1 |
Nakaya, H | 1 |
Takeda, Y | 1 |
Tohse, N | 1 |
Kanno, M | 1 |
Deutsch, N | 1 |
Klitzner, TS | 1 |
Haddad, GG | 1 |
Maier-Rudolph, W | 1 |
von Beckerath, N | 1 |
Mehrke, G | 1 |
Günther, K | 1 |
Goedel-Meinen, L | 1 |
Yuan, XJ | 1 |
Tod, ML | 1 |
Rubin, LJ | 1 |
Blaustein, MP | 1 |
Wilde, AA | 1 |
Escande, D | 1 |
Schumacher, CA | 1 |
Thuringer, D | 1 |
Mestre, M | 1 |
Fiolet, JW | 1 |
Janse, MJ | 1 |
Krnjević, K | 1 |
Peach, JL | 1 |
Sanguinetti, MC | 1 |
Scott, AL | 1 |
Zingaro, GJ | 1 |
Siegl, PK | 1 |
Ben Ari, Y | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Liberal Versus Restrictive Platelet Transfusion for Treatment of Hemodynamically Significant Patent Ductus Arteriosus in Thrombocytopenic Preterm Neonates- A Randomized Open Label, Controlled Trial[NCT03022253] | Phase 3 | 44 participants (Anticipated) | Interventional | 2016-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
136 other studies available for glyburide and Anoxemia
Article | Year |
---|---|
The Role of Mitochondrial K
Topics: Adenosine Triphosphate; Animals; Glyburide; Hypoxia; KATP Channels; Male; Myocardial Infarction; Rat | 2022 |
NLRP3 inflammasome is expressed and regulated in human islets.
Topics: Cell Death; Gene Expression Regulation; Glyburide; Humans; Hypoxia; Inflammasomes; Interleukin-1beta | 2018 |
Volatile anesthetic sevoflurane pretreatment alleviates hypoxia-induced potentiation of excitatory inputs to striatal medium spiny neurons of mice.
Topics: Action Potentials; Animals; Central Nervous System Sensitization; Corpus Striatum; Coumaric Acids; E | 2019 |
Hypoxia augments NaHS-induced ANP secretion via KATP channel, HIF-1α and PPAR-γ pathway.
Topics: 2-Methoxyestradiol; Anilides; Animals; Atrial Natriuretic Factor; Bosentan; Gene Expression Regulati | 2019 |
Comparison of effects of ATP-gated potassium channel blockers on activity variations of rat CA1 pyramidal neurons in hippocampal slices triggered by short-term hypoxia.
Topics: Animals; Decanoic Acids; Glyburide; Hippocampus; Hydroxy Acids; Hypoxia; Male; Potassium Channel Blo | 2013 |
Opioid receptors mediate enhancement of ACh-induced aorta relaxation by chronic intermittent hypobaric hypoxia.
Topics: Acetylcholine; Altitude; Animals; Aorta, Thoracic; Glyburide; Hypoxia; KATP Channels; Male; Rats; Ra | 2013 |
Hypothermia improves oral and gastric mucosal oxygenation during hypoxic challenges.
Topics: Animals; Cardiac Output; Cardiotonic Agents; Cross-Over Studies; Disease Models, Animal; Dogs; Femal | 2014 |
[Glybenclamide regulate ERK1/2 signal pathway during hypoxia hypercapnia pulmonary vasoconstriction in rats].
Topics: Animals; Glyburide; Hypercapnia; Hypoxia; In Vitro Techniques; Male; MAP Kinase Signaling System; Pu | 2014 |
K(ATP) channels and MPTP are involved in the cardioprotection bestowed by chronic intermittent hypobaric hypoxia in the developing rat.
Topics: Animals; Atmospheric Pressure; Atractyloside; Cardiotonic Agents; Cyclosporine; Decanoic Acids; Diaz | 2015 |
15-oxo-ETE-induced internal carotid artery constriction in hypoxic rats is mediated by potassium channels.
Topics: 4-Aminopyridine; Animals; Arachidonic Acids; Carotid Artery, Internal; Glyburide; Hydroxyprostagland | 2016 |
Glibenclamide reduces inflammation, vasogenic edema, and caspase-3 activation after subarachnoid hemorrhage.
Topics: Animals; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain Edema; Carotid Artery Injurie | 2009 |
Effects of desflurane and propofol on electrophysiological parameters during and recovery after hypoxia in rat hippocampal slice CA1 pyramidal cells.
Topics: Action Potentials; Animals; Benzophenanthridines; Desflurane; Dose-Response Relationship, Drug; Enzy | 2009 |
Blockade of K(ATP) channels reduces endothelial hyperpolarization and leukocyte recruitment upon reperfusion after hypoxia.
Topics: Animals; Cats; Cell Membrane; Endothelium, Vascular; Gelatin; Glyburide; Humans; Hypoxia; KATP Chann | 2009 |
Impact of modulators of mitochondrial ATP-sensitive potassium channel (mitoK(ATP)) on hypoxic pulmonary vasoconstriction.
Topics: Animals; Arteries; Coronary Vessels; Decanoic Acids; Glyburide; Heart; Hydroxy Acids; Hypoxia; Immun | 2009 |
Hydrogen sulfide and cerebral microvascular tone in newborn pigs.
Topics: Animals; Animals, Newborn; Arterioles; Brain Chemistry; Capillaries; Cerebrovascular Circulation; Cy | 2011 |
The effects of levosimendan and glibenclamide on circulatory and metabolic variables in a canine model of acute hypoxia.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Dogs; Glyburide; Hemodynamics; Hydrazones; Hypoglyce | 2011 |
Intermittent hypoxia in rats increases myogenic tone through loss of hydrogen sulfide activation of large-conductance Ca(2+)-activated potassium channels.
Topics: 1-Methyl-3-isobutylxanthine; Air Pollutants; Animals; Blood Pressure; Endothelium, Vascular; Glyburi | 2011 |
Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Blotting, Western; Chloramphe | 2012 |
Glibenclamide reduces proinflammatory cytokines in an ex vivo model of human endotoxinaemia under hypoxaemic conditions.
Topics: Adult; Anti-Inflammatory Agents; Calcium; Cytokines; Dose-Response Relationship, Drug; Endotoxemia; | 2011 |
Vulnerability of the retinal microvasculature to hypoxia: role of polyamine-regulated K(ATP) channels.
Topics: Animals; Apoptosis; Disease Models, Animal; Eflornithine; Glyburide; Hypoxia; Ion Transport; KATP Ch | 2011 |
Facilitation of chronic intermittent hypobaric hypoxia on carotid sinus baroreflex in anesthetized rats.
Topics: Anesthesia; Animals; Baroreflex; Blood Gas Analysis; Blood Pressure; Body Weight; Carotid Sinus; Gly | 2012 |
Hypobaric intermittent hypoxia attenuates hypoxia-induced depressor response.
Topics: Altitude; Animals; Baroreflex; Blood Pressure; Environment, Controlled; Glyburide; Heart Rate; Hypox | 2012 |
Impaired hypoxic coronary vasodilation and ATP-sensitive potassium channel function: a manifestation of diabetic microangiopathy in humans?
Topics: Adenosine Triphosphate; Coronary Vessels; Diabetic Angiopathies; Glyburide; Humans; Hypoxia; Microci | 2003 |
Diabetes mellitus impairs vasodilation to hypoxia in human coronary arterioles: reduced activity of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Age Factors; Arterioles; Bradykinin; Coronary Vessels; Diabetes Mellitus; Fe | 2003 |
Effect of acute hypoxia on ATP-sensitive potassium currents in substantia gelatinosa neurons of juvenile rats.
Topics: Acute Disease; Adenosine Triphosphate; Age Factors; Animals; Anti-Arrhythmia Agents; Barium; Cesium; | 2003 |
ATP-dependent potassium channels involved in the cardiac protection induced by intermittent hypoxia against ischemia/reperfusion injury.
Topics: Animals; Calcium; Decanoic Acids; Glyburide; Heart Ventricles; Hemodynamics; Hydroxy Acids; Hypoxia; | 2003 |
The role of K+ channels in vasorelaxation induced by hypoxia and the modulator effects of lidocaine in the rat carotid artery.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Carotid Artery, Common; Cromakalim; Dose-Re | 2003 |
Contractile responses of isolated rat mesenteric arteries to acute episodes of severe hypoxia and subsequent reoxygenation.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 4-Aminopyridine; Adenosine Triph | 2004 |
Myocardial impairment in chronic hypoxia is abolished by short aeration episodes: involvement of K+ATP channels.
Topics: Animals; Apoptosis; Chronic Disease; Glyburide; Heart; Hypoxia; In Situ Nick-End Labeling; Male; Myo | 2004 |
Acute systemic hypoxia elevates venous but not interstitial potassium of dog skeletal muscle.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Carbon Dioxide; Dogs; Female; Glyburide; Hydrogen-Io | 2005 |
Cardioprotective effects of K ATP channel activation during hypoxia in goldfish Carassius auratus.
Topics: Acclimatization; Action Potentials; Analysis of Variance; Animals; Cyclic GMP; Diazoxide; Glyburide; | 2005 |
Glibenclamide reveals role for endothelin in hypoxia-induced vasoconstriction in rat intrapulmonary arteries.
Topics: Animals; Anti-Arrhythmia Agents; Carboxylic Acids; Dose-Response Relationship, Drug; Endothelin Rece | 2005 |
Acute hypoxia induces vasodilation and increases coronary blood flow by activating inward rectifier K(+) channels.
Topics: Acute Disease; Adenine; Animals; Blood Pressure; Carbazoles; Coronary Circulation; Cyclic AMP-Depend | 2007 |
Hyperoxia confers myocardial protection in mechanically ventilated rats through the generation of free radicals and opening of mitochondrial ATP-sensitive potassium channels.
Topics: Acetylcysteine; Animals; Blood Pressure; Coronary Circulation; Decanoic Acids; Disease Models, Anima | 2008 |
Mitochondrial ATP-sensitive K+ channels regulate NMDAR activity in the cortex of the anoxic western painted turtle.
Topics: Adenosine Triphosphate; Animals; Calcium; Cerebral Cortex; Cromakalim; Decanoic Acids; Diazoxide; Gl | 2008 |
Critical role of endothelium in sustained arterial contraction during prolonged hypoxia.
Topics: Adenosine Triphosphate; Amino Acid Oxidoreductases; Animals; Aorta, Thoracic; Arginine; Endothelium, | 1995 |
Relaxation of the aorta during hypoxia is impaired in chronically hypertensive rats.
Topics: Animals; Aorta; Charybdotoxin; Chronic Disease; Glyburide; Hypertension; Hypoxia; Male; Nitroprussid | 1995 |
Ion channel involvement in anoxic depolarization induced by cardiac arrest in rat brain.
Topics: Adenosine Triphosphate; Animals; Benzothiazoles; Calcium; Dizocilpine Maleate; Flunarizine; Glyburid | 1995 |
Effect of L-NMMA, cromakalim, and glibenclamide on cerebral blood flow in hypercapnia and hypoxia.
Topics: Animals; Arginine; Arteries; Benzopyrans; Cerebrovascular Circulation; Cromakalim; Glyburide; Hyperc | 1995 |
Opioids contribute to hypoxia-induced pial artery dilation through activation of ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Blood Vessels; Female; Glyburide; Hypoxia; Male; Na | 1995 |
Effects of levcromakalim and glibenclamide on paced guinea-pig atrial strips exposed to hypoxia.
Topics: Animals; Benzopyrans; Cardiac Pacing, Artificial; Cromakalim; Deoxyglucose; Dose-Response Relationsh | 1995 |
Hypoxia-induced activation of KATP channels limits energy depletion in the guinea pig heart.
Topics: Adenosine Triphosphate; Animals; Energy Metabolism; Female; Glyburide; Guinea Pigs; Hypoxia; Myocard | 1995 |
Role for ATP-sensitive K+ channel in the development of A-V block during hypoxia.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Atrioventricular Node; Deoxyglucose; Female; Glu | 1995 |
Cellular mechanisms of hypoxia-induced contraction in human and rat pulmonary arteries.
Topics: Aged; Animals; Benzopyrans; Calcium; Calcium Channels; Cromakalim; Glyburide; Humans; Hypoxia; In Vi | 1995 |
Glibenclamide inhibits hypoxic relaxation of isolated porcine coronary arteries under conditions of impaired glycolysis.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adenosine Triphosphate; Animals; | 1994 |
Influence of N omega-nitro-L-arginine methyl ester, LY83583, glybenclamide and L158809 on pulmonary circulation.
Topics: Aminoquinolines; Angiotensin Receptor Antagonists; Animals; Arginine; Drug Interactions; Glyburide; | 1994 |
Protective effect of hypoxia on mechanical and metabolic changes induced by hydrogen peroxide in rat hearts.
Topics: Animals; Glyburide; Heart; Hydrogen Peroxide; Hypoxia; In Vitro Techniques; Male; Myocardium; Purine | 1995 |
The sensitivity of coronary vascular tone to glibenclamide: a study on the isolated perfused guinea pig heart.
Topics: Animals; Benzopyrans; Biological Assay; Coronary Vessels; Cromakalim; Glyburide; Guinea Pigs; Hypoxi | 1994 |
Protection of atrial function in hypoxia by high potassium concentration.
Topics: Adenine Nucleotides; Animals; Cardiac Pacing, Artificial; Diastole; Energy Metabolism; Evaluation St | 1994 |
Activation of potassium channels contributes to hypoxic injury in proximal tubules.
Topics: Adenosine Triphosphate; Animals; Biological Transport; Diazoxide; DNA Damage; Dose-Response Relation | 1994 |
Inhibition of hypoxia-induced relaxation of rabbit isolated coronary arteries by NG-monomethyl-L-arginine but not glibenclamide.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arginine; Capsaicin; Coronary Vessels; Endothelium, Vasc | 1994 |
Role of endothelium and arterial K+ channels in mediating hypoxic dilation of middle cerebral arteries.
Topics: Animals; Cerebral Arteries; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Male; Ox | 1994 |
A link between adenosine, ATP-sensitive K+ channels, potassium and muscle vasodilatation in the rat in systemic hypoxia.
Topics: 2-Chloroadenosine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Hypoxia; Muscles; Potassiu | 1993 |
ATP-sensitive K+ channels mediate dilatation of cerebral arterioles during hypoxia.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arterioles; Brain; Glyburide; Hypoxia; Male; Picolines; | 1994 |
Hypoxia inhibits myogenic reactivity of renal afferent arterioles by activating ATP-sensitive K+ channels.
Topics: Adenosine Triphosphate; Animals; Arterioles; Glyburide; Hypoxia; Kidney; NAD; Potassium Channels; Ra | 1994 |
Role of potassium channels in hypoxic relaxation of porcine bronchi in vitro.
Topics: Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Carbachol; Cromakalim; Dose-Response Relations | 1994 |
NIP-121 is more effective than nifedipine in acutely reversing chronic pulmonary hypertension.
Topics: Altitude; Animals; Chronic Disease; Glyburide; Hemodynamics; Hypertension, Pulmonary; Hypoxia; Male; | 1993 |
O2 occlusion and cyanide induced immediate relaxation and contraction of murine skeletal muscle.
Topics: Animals; Caffeine; Cyanides; Electric Stimulation; Glyburide; Hypoxia; In Vitro Techniques; Mice; Mi | 1993 |
Endothelin-1 produces pulmonary vasodilation in the intact newborn lamb.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Animals, Newborn; Argin | 1993 |
Endothelium-dependent and -independent responses to severe hypoxia in rat pulmonary artery.
Topics: Acetylcholine; Animals; Arginine; Endothelium, Vascular; Glyburide; Hemoglobins; Hypoxia; In Vitro T | 1993 |
Differential class III and glibenclamide effects on action potential duration in guinea-pig papillary muscle during normoxia and hypoxia/ischaemia.
Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Electrophysiology; Glyburide; Guinea Pigs; Heart | 1993 |
Dilator effect of endothelins in pulmonary circulation: changes associated with chronic hypoxia.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Arginine; Autoradiograp | 1993 |
Attenuation by phentolamine of hypoxia and levcromakalim-induced abbreviation of the cardiac action potential.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Drug Interactions; Gluc | 1993 |
Chronic hypoxia is associated with reduced delayed rectifier K+ current in rat pulmonary artery muscle cells.
Topics: 4-Aminopyridine; Animals; Chronic Disease; Electric Conductivity; Electrophysiology; Glyburide; Hypo | 1994 |
Possible involvement of ATP-sensitive K+ channels in the inhibition of rat central adrenergic neurotransmission under hypoxia.
Topics: Adenosine Triphosphate; Animals; Cocaine; Dose-Response Relationship, Drug; Glyburide; Hypoxia; In V | 1993 |
Hypoxic relaxation in functionally intact cattle coronary artery segments involves K+ ATP channels.
Topics: Adenosine; Adenosine Triphosphate; Animals; Arteries; Calcium; Calcium Channel Blockers; Cattle; Cor | 1995 |
Glibenclamide does not reverse attenuated vasoreactivity to acute or chronic hypoxia.
Topics: Acute Disease; Adenosine Triphosphate; Animals; Benzopyrans; Blood Gas Analysis; Blood Pressure; Chr | 1995 |
Hypoxic preconditioning in isolated rat hearts: non-involvement of activation of adenosine A1 receptor, Gi protein, and ATP-sensitive K+ channel.
Topics: Adenosine Triphosphate; Analysis of Variance; Animals; Calcium Channel Blockers; Creatine Kinase; Gl | 1995 |
Simultaneous recording of ATP-sensitive K+ current and intracellular Ca2+ in anoxic rat ventricular myocytes. Effects of glibenclamide.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyanides; Electric Conductivity; Fura-2; Glyburide; Hypoxi | 1996 |
Oxygen causes fetal pulmonary vasodilation through activation of a calcium-dependent potassium channel.
Topics: Alkaloids; Aminoquinolines; Animals; Carbazoles; Charybdotoxin; Endothelium, Vascular; Enzyme Inhibi | 1996 |
Role of K+ in regulating hypoxic cerebral blood flow in the rat: effect of glibenclamide and ouabain.
Topics: Animals; Blood Pressure; Brain Ischemia; Cerebrovascular Circulation; Extracellular Space; Female; G | 1996 |
Critical oxygen extraction in piglet hindlimb is impaired after inhibition of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hindlimb; Hypoxia; Ischemia; Muscle, Smooth, Vascular; O | 1996 |
In vitro hypoxia on rat pulmonary artery: effects on contractions to spasmogens and role of KATP channels.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Animals; Benzopyrans; Cromakalim | 1996 |
ATP-sensitive K+ channels are functional in expiratory neurones of normoxic cats.
Topics: Adenosine Triphosphate; Animals; Bicuculline; Blood-Brain Barrier; Brain Stem; Cats; Female; Glyburi | 1996 |
Adenine nucleotides via activation of ATP-sensitive K+ channels modulate hypoxic response in rat pulmonary artery.
Topics: Adenine Nucleotides; Adenosine Triphosphate; Animals; Glyburide; Hyperglycemia; Hypoglycemic Agents; | 1996 |
Role of nitric oxide, cyclic nucleotides, and the activation of ATP-sensitive K+ channels in the contribution of adenosine to hypoxia-induced pial artery dilation.
Topics: Adenosine; Adenosine Deaminase; Adenosine Triphosphate; Animals; Arteries; Blood Pressure; Cyclic AM | 1997 |
Sulphonylureas reverse hypoxia induced K(+)-conductance increase in substantia nigra pars reticulata neurones.
Topics: Animals; Glyburide; Hypoxia; Membrane Potentials; Potassium Channels; Rats; Substantia Nigra; Tetrod | 1996 |
ATP-sensitive potassium channels in isolated rat aorta during physiologic, hypoxic, and low-glucose conditions.
Topics: Adenosine Triphosphate; Animals; Aorta, Thoracic; Benzopyrans; Cromakalim; Dose-Response Relationshi | 1997 |
Increased tolerance of the chronically hypoxic immature heart to ischemia. Contribution of the KATP channel.
Topics: Analysis of Variance; Animals; Animals, Newborn; Benzopyrans; Coronary Circulation; Dihydropyridines | 1997 |
Hypoxia-induced hyperpolarization is not associated with vasodilation of bovine coronary resistance arteries.
Topics: Acetylcholine; Animals; Benzopyrans; Bradykinin; Calcium; Cattle; Coronary Vessels; Cromakalim; Endo | 1997 |
KATP channel activation in a rabbit model of chronic myocardial hypoxia.
Topics: Action Potentials; Adenosine Diphosphate; Adenosine Triphosphate; Animals; Animals, Newborn; Chronic | 1997 |
ATP-dependent K+ channel activation in isolated normal and hypertensive newborn and adult porcine pulmonary vessels.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Antihypertensive Agents; Cromakalim; Cyclooxygena | 1997 |
Mechanism of hypoxic K loss in rabbit ventricle.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Biological Transport; Cromakalim; Glyburide; Heart | 1997 |
Anoxia-induced activation of ATP-sensitive K+ channels in guinea pig ventricular cells and its modulation by glycolysis.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Glyburide; Glycolysis; Guinea Pigs; Hypoxia; Ion | 1997 |
Effects of ischemia on cerebral arteriolar dilation to arterial hypoxia in piglets.
Topics: Adenosine; Adenosine Triphosphate; Administration, Topical; Analysis of Variance; Animals; Arteriole | 1998 |
Hypoxia activates ATP-dependent potassium channels in inspiratory neurones of neonatal mice.
Topics: Adenosine Triphosphate; Animals; Animals, Newborn; Calcium; Diazoxide; Electric Stimulation; Glyburi | 1998 |
ATP-sensitive K+ channel blocker glibenclamide and diaphragm fatigue during normoxia and hypoxia.
Topics: Adenosine Triphosphate; Animals; Diaphragm; Electric Stimulation; Glyburide; Hypoglycemic Agents; Hy | 1998 |
Potassium channels modulate hypoxic pulmonary vasoconstriction.
Topics: 4-Aminopyridine; Animals; Blood Pressure; Dogs; Female; Glyburide; Hypoxia; In Vitro Techniques; Mal | 1998 |
Resting potentials and potassium currents during development of pulmonary artery smooth muscle cells.
Topics: Aging; Animals; Animals, Newborn; Calcium; Electric Conductivity; Glyburide; Hypoxia; Membrane Poten | 1998 |
Relationship among NO, the KATP channel, and opioids in hypoxic pial artery dilation.
Topics: Adenosine Triphosphate; Animals; Arteries; Blood Pressure; Calcitonin Gene-Related Peptide; Cromakal | 1998 |
Acquired resistance of a mammalian cell line to hypoxia-reoxygenation through cotransfection of Kir6.2 and SUR1 clones.
Topics: Animals; Calcium; COS Cells; Genetic Predisposition to Disease; Glyburide; Glycosyltransferases; Hyp | 1998 |
Anoxia differentially modulates multiple K+ currents and depolarizes neonatal rat adrenal chromaffin cells.
Topics: Animals; Animals, Newborn; Chromaffin Cells; Electric Stimulation; Electrophysiology; Glyburide; Hyp | 1998 |
Cellular mechanisms by which adenosine induces vasodilatation in rat skeletal muscle: significance for systemic hypoxia.
Topics: Adenosine; Animals; Antihypertensive Agents; Blood Pressure; Cromakalim; Enzyme Inhibitors; Femoral | 1999 |
ATP-sensitive K+ channel activation provides transient protection to the anoxic turtle brain.
Topics: Adenosine Triphosphate; Animals; Brain; Diacetyl; Extracellular Space; Glyburide; Hypoxia; Ouabain; | 1998 |
Electrical and mechanical responses of rat middle cerebral arteries to reduced PO2 and prostacyclin.
Topics: Animals; Cerebral Arteries; Electrophysiology; Epoprostenol; Glyburide; Hypoxia; Iloprost; In Vitro | 1999 |
A role for KATP+-channels in mediating the elevations of cerebral blood flow and arterial pressure by hypoxic stimulation of oxygen-sensitive neurons of rostral ventrolateral medulla.
Topics: Adenosine Triphosphate; Animals; Blood Pressure; Brain Chemistry; Cerebrovascular Circulation; Glybu | 1999 |
Role of potassium channels and nitric oxide in the relaxant effects elicited by beta-adrenoceptor agonists on hypoxic vasoconstriction in the isolated perfused lung of the rat.
Topics: Adrenergic beta-Agonists; Animals; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Glyburide; Hypoxia; | 1999 |
Protection of human myocardium in vitro by K(ATP) activation with low concentrations of bimakalim.
Topics: Adenosine Triphosphate; Adult; Benzopyrans; Dihydropyridines; Dobutamine; Dose-Response Relationship | 1999 |
Cerebral blood flow during hemodilution and hypoxia in rats : role of ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Cerebrovascular Circulation; Glyburide; Hemodilution; Hypoxia; Male | 1999 |
Enhanced beta-receptor-mediated vasorelaxation in hypoxic porcine coronary artery.
Topics: Animals; Arteries; Coronary Vessels; Cyclic AMP; Endothelin-1; Glyburide; Hypoxia; In Vitro Techniqu | 1999 |
Role of an ATP-sensitive potassium channel opener, YM934, in mitochondrial energy production in ischemic/reperfused heart.
Topics: Adenosine Triphosphate; Animals; Anti-Arrhythmia Agents; Benzoxazines; Creatine Kinase; Cyclic N-Oxi | 1999 |
Adaptation to high altitude hypoxia protects the rat heart against ischemia-induced arrhythmias. Involvement of mitochondrial K(ATP) channel.
Topics: Acclimatization; Altitude; Animals; Arrhythmias, Cardiac; Glyburide; Heart; Heart Rate; Heart Ventri | 1999 |
Mechanism of hypoxic pulmonary vasoconstriction involves ET(A) receptor-mediated inhibition of K(ATP) channel.
Topics: Adenosine Triphosphate; Animals; Blood; Endothelin Receptor Antagonists; Glyburide; Hypoxia; In Vitr | 2000 |
Activation of sulphonylurea-sensitive channels and the NO-cGMP pathway decreases the heart rate response to sympathetic nerve stimulation.
Topics: Analysis of Variance; Animals; Cyclic GMP; Diazoxide; Electric Stimulation; Enzyme Inhibitors; Glybu | 2000 |
Voltage-gated potassium channels in human ductus arteriosus.
Topics: 4-Aminopyridine; Charybdotoxin; Cyclooxygenase Inhibitors; Ductus Arteriosus; Ductus Arteriosus, Pat | 2000 |
Analysis of single K(ATP) channels in mammalian dentate gyrus granule cells.
Topics: Animals; Antihypertensive Agents; Dentate Gyrus; Diazoxide; Glyburide; Hypoglycemia; Hypoglycemic Ag | 2000 |
Increased mitochondrial K(ATP) channel activity during chronic myocardial hypoxia: is cardioprotection mediated by improved bioenergetics?
Topics: Adaptation, Physiological; Adenosine Triphosphate; Animals; Animals, Newborn; Benzopyrans; Cell Hypo | 2000 |
Nitric oxide activates the sarcolemmal K(ATP) channel in normoxic and chronically hypoxic hearts by a cyclic GMP-dependent mechanism.
Topics: Action Potentials; Animals; Animals, Newborn; Blood Pressure; Cyclic GMP; Electron Spin Resonance Sp | 2001 |
Effects of phosphodiesterase inhibitors on hypoxic pulmonary vasoconstriction. Influence of K(+) channels and nitric oxide.
Topics: 4-Aminopyridine; Animals; Apamin; Charybdotoxin; Dose-Response Relationship, Drug; Enzyme Inhibitors | 2001 |
Intrinsic optical signals in respiratory brain stem regions of mice: neurotransmitters, neuromodulators, and metabolic stress.
Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Adenosine; Adenosine Triphosphate; Animals; Animals, Newborn; | 2001 |
Hemodynamic effects of levcromakalim in neonatal porcine pulmonary hypertension.
Topics: Animals; Animals, Newborn; Blood Pressure; Cromakalim; Disease Models, Animal; Glyburide; Hemodynami | 2001 |
Activation of ATP-sensitive potassium channels in hypoxic cardiac failure is not mediated by adenosine-1 receptors in the isolated rat heart.
Topics: Action Potentials; Animals; Blood Pressure; Female; Glyburide; Heart Rate; Hypoglycemic Agents; Hypo | 2001 |
Reduction of Ca(2+) channel activity by hypoxia in human and porcine coronary myocytes.
Topics: Animals; Calcium; Calcium Channels, L-Type; Coronary Vessels; Cytosol; Fluorometry; Glyburide; Human | 2002 |
Analysis of the effects of graded levels of hypoxia on noradrenaline-evoked contraction in the rat iliac artery in vitro.
Topics: Adrenergic alpha-Agonists; Animals; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Calcium | 2002 |
Role of myocardium and endothelium in coronary vascular smooth muscle responses to hypoxia.
Topics: Acetylcholine; Animals; Arachidonic Acid; Coronary Vessels; Endothelium, Vascular; Glyburide; Heart; | 2002 |
Exercise training alters an anoxia-induced, glibenclamide-sensitive current in rat ventricular cardiocytes.
Topics: Adenosine Triphosphate; Animals; Female; Glyburide; Heart Ventricles; Hypoglycemic Agents; Hypoxia; | 2002 |
Mitochondrial ATP-sensitive K+ channels influence force development and anoxic contractility in a flatfish, yellowtail flounder Limanda ferruginea, but not Atlantic cod Gadus morhua heart.
Topics: Aerobiosis; Animals; ATP-Binding Cassette Transporters; Decanoic Acids; Diazoxide; Fishes; Flounder; | 2002 |
Opposing actions of tolbutamide and glibenclamide on hypoxic pulmonary vasoconstriction.
Topics: Animals; Benzopyrans; Cromakalim; Diazoxide; Glyburide; Hypoxia; In Vitro Techniques; Lung; Male; Po | 1992 |
Influence of ATP-sensitive potassium channel blocker on hypoxia-induced damage of isolated guinea pig heart.
Topics: Adenosine Triphosphate; Animals; Glyburide; Guinea Pigs; Heart Rate; Hypoxia; L-Lactate Dehydrogenas | 1992 |
Anoxia induces time-independent K+ current through KATP channels in isolated heart cells of the guinea-pig.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Glyburide; Guinea Pigs; Heart; Heart Ventricles; | 1992 |
Evidence that epithelium-dependent relaxation of vascular smooth muscle detected by co-axial bioassays is not attributable to hypoxia.
Topics: Animals; Aorta; Benzopyrans; Biological Assay; Biological Factors; Cromakalim; Epithelium; Glyburide | 1992 |
Hypoxia-evoked dilatation of rabbit isolated basilar arteries is not mediated by the opening of glibenclamide-sensitive potassium channels.
Topics: Animals; Basilar Artery; Benzopyrans; Cromakalim; Glyburide; Hypoxia; In Vitro Techniques; Male; Pot | 1992 |
Effects of glibenclamide and tolbutamide on ischemia- and ouabain-induced arrhythmias and membrane potentials of ventricular myocardium from rat and guinea pig.
Topics: Animals; Arrhythmias, Cardiac; Dose-Response Relationship, Drug; Female; Glyburide; Guinea Pigs; Hyp | 1991 |
Effects of inhibitors of EDRF and EDHF on vasoreactivity of perfused rat lungs.
Topics: Analysis of Variance; Angiotensin II; Animals; Biological Factors; Blood Pressure; Glyburide; Hemogl | 1991 |
K+ channels and metabolic inhibition in cardiac cells.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hypoxia; Myocardium; Potassium Channels; Sodium | 1991 |
ATP-dependent K+ channels modulate vasoconstrictor responses to severe hypoxia in isolated ferret lungs.
Topics: Adenosine Triphosphate; Animals; Benzopyrans; Cromakalim; Ferrets; Glucose; Glyburide; Hypoxia; In V | 1991 |
Effects of ATP-sensitive K+ channel blockers on the action potential shortening in hypoxic and ischaemic myocardium.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Circulation; Coronary Disease; Dogs; Fe | 1991 |
Activation of cardiac ATP-sensitive K+ current during hypoxia: correlation with tissue ATP levels.
Topics: Action Potentials; Adenine Nucleotides; Adenosine Triphosphate; Anaerobiosis; Animals; Glyburide; Hy | 1991 |
Effect of anoxia on intracellular and extracellular potassium activity in hypoglossal neurons in vitro.
Topics: Animals; Cells, Cultured; Electrophysiology; Extracellular Space; Glyburide; Hypoglossal Nerve; Hypo | 1991 |
Hypoxic dilation of coronary arteries is mediated by ATP-sensitive potassium channels.
Topics: Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Bradykinin; Coronary Vessels; | 1990 |
Contrasting effects of hypoxia on tension in rat pulmonary and mesenteric arteries.
Topics: Animals; Benzopyrans; Cromakalim; Endothelium, Vascular; Glyburide; Hypoxia; In Vitro Techniques; Ma | 1990 |
Potassium accumulation in the globally ischemic mammalian heart. A role for the ATP-sensitive potassium channel.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Coronary Disease; Dinitrophenols; Electric Condu | 1990 |
Adenosine triphosphate-sensitive potassium channels in anoxia.
Topics: Adenosine Triphosphate; Animals; Diazoxide; Electrophysiology; Glyburide; Hippocampus; Hypoxia; Neur | 1990 |
Inhibitor of ATP-sensitive K+ channel alters neither hypoxic contraction nor relaxation of rat aorta.
Topics: Adenosine Triphosphate; Animals; Aorta; Glyburide; Hypoxia; Potassium Channels; Rats; Vasoconstricti | 1990 |
BRL 34915 (cromakalim) activates ATP-sensitive K+ current in cardiac muscle.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Antihypertensive Agents; Benzopyrans; Cromakalim | 1988 |
Effect of glibenclamide, a selective blocker of an ATP-K+ channel, on the anoxic response of hippocampal neurones.
Topics: Adenosine Triphosphate; Animals; Glyburide; Hippocampus; Hypoxia; In Vitro Techniques; Male; Neurons | 1989 |