glyburide has been researched along with Allodynia in 16 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The accompanying mechanical allodynia may be reduced by the intrathecal administration of adenosine." | 3.77 | Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats. ( Hahm, KD; Jeong, SM; Kim, YK; Lee, C; Leem, JG; Park, PH; Shin, JW; Song, JG, 2011) |
| "The present work evaluated the effects of the methanol extract of the bulbs of Dioscorea bulbifera in inflammatory and neuropathic models of pain and further investigated its possible mechanism of action." | 3.76 | Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation. ( Andrade, EL; Calixto, JB; Dutra, RC; Nguelefack, TB; Paszcuk, AF; Tapondjou, LA, 2010) |
| "Metformin was administered per os (p." | 1.51 | Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms. ( Augusto, PSA; Batista, CRA; Braga, AV; Coelho, MM; Costa, SOAM; Dutra, MMGB; Goulart, FA; Machado, RR; Melo, ISF; Morais, MI; Rodrigues, FF, 2019) |
| "Even ongoing inflammatory edema and mechanical allodynia were reduced by leflunomide." | 1.48 | Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1. ( Augusto, PSA; Brito, AMS; Coelho, MM; Costa, SOAM; Dutra, MGMB; Godin, AM; Goulart, FA; Ísis Morais, M; Machado, RR; Melo, ISF; Menezes, RR; Rodrigues, FF, 2018) |
| "Bone cancer pain is a major clinical problem and remains difficult to treat." | 1.40 | Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain. ( Fan, L; Pan, HL; Ren, J; Tian, Y; Wang, X; Wang, Y; Wu, J; Xia, H; Xu, L; Yang, S; Yao, W; Zhang, C; Zhang, D, 2014) |
| "This blockade of PGE2 mechanical hyperalgesia induced by diclofenac (100 microg/paw) was antagonized in a dose-dependent manner by intraplantar administration of the sulphonylureas glibenclamide (40, 80 and 160 microg) and tolbutamide (80, 160 and 320 microg), specific blockers of ATP-sensitive K+ channels, and it was observed even when the hyperalgesic agent used was carrageenin, while the antinociceptive action of indomethacin (200 microg/paw), a typical cyclo-oxygenase inhibitor, over carrageenin-induced hyperalgesia was not affected by this treatment." | 1.32 | Diclofenac-induced peripheral antinociception is associated with ATP-sensitive K+ channels activation. ( Alves, DP; Duarte, ID; Leite, R; Tatsuo, MA, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (37.50) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 1 (6.25) | 2.80 |
| Authors | Studies |
|---|---|
| Christensen, SL | 1 |
| Munro, G | 1 |
| Petersen, S | 1 |
| Shabir, A | 1 |
| Jansen-Olesen, I | 1 |
| Kristensen, DM | 1 |
| Olesen, J | 1 |
| Raafat, K | 1 |
| El-Lakany, A | 1 |
| Brito, AMS | 1 |
| Godin, AM | 1 |
| Augusto, PSA | 2 |
| Menezes, RR | 1 |
| Melo, ISF | 2 |
| Dutra, MGMB | 1 |
| Costa, SOAM | 2 |
| Goulart, FA | 2 |
| Rodrigues, FF | 2 |
| Ísis Morais, M | 1 |
| Machado, RR | 2 |
| Coelho, MM | 2 |
| Braga, AV | 1 |
| Morais, MI | 1 |
| Dutra, MMGB | 1 |
| Batista, CRA | 1 |
| Quiñonez-Bastidas, GN | 1 |
| Cervantes-Durán, C | 1 |
| Rocha-González, HI | 2 |
| Murbartián, J | 1 |
| Granados-Soto, V | 2 |
| Redondo-Castro, E | 1 |
| Hernández, J | 1 |
| Mahy, N | 1 |
| Navarro, X | 1 |
| Xia, H | 1 |
| Zhang, D | 1 |
| Yang, S | 1 |
| Wang, Y | 1 |
| Xu, L | 1 |
| Wu, J | 1 |
| Ren, J | 1 |
| Yao, W | 1 |
| Fan, L | 1 |
| Zhang, C | 1 |
| Tian, Y | 1 |
| Pan, HL | 1 |
| Wang, X | 1 |
| Nguelefack, TB | 1 |
| Dutra, RC | 1 |
| Paszcuk, AF | 1 |
| Andrade, EL | 1 |
| Tapondjou, LA | 1 |
| Calixto, JB | 2 |
| Song, JG | 1 |
| Hahm, KD | 1 |
| Kim, YK | 1 |
| Leem, JG | 1 |
| Lee, C | 1 |
| Jeong, SM | 1 |
| Park, PH | 1 |
| Shin, JW | 1 |
| Romero, TR | 1 |
| Duarte, ID | 4 |
| Santos, AR | 1 |
| Trentin, AP | 1 |
| Ferreira, J | 1 |
| Yunes, RA | 1 |
| Alves, DP | 2 |
| Tatsuo, MA | 1 |
| Leite, R | 1 |
| Terán-Rosales, F | 1 |
| Reyes-García, G | 1 |
| Medina-Santillán, R | 1 |
| Rodríguez-Silverio, J | 1 |
| Flores-Murrieta, FJ | 1 |
| Amarante, LH | 1 |
| Menéndez, L | 1 |
| Juárez, L | 1 |
| García, V | 1 |
| Hidalgo, A | 1 |
| Baamonde, A | 1 |
| Soares, AC | 1 |
16 other studies available for glyburide and Allodynia
| Article | Year |
|---|---|
ATP sensitive potassium (K
Topics: Animals; Calcitonin Gene-Related Peptide; Dura Mater; Glyburide; Hyperalgesia; KATP Channels; Mice; | 2020 |
Combination of Rheum ribes and Metformin Against Diabetes, Thermal Hyperalgesia, and Tactile Allodynia in a Mice Model.
Topics: Animals; Antioxidants; Biomarkers; Blood Glucose; Diabetes Mellitus, Experimental; Glyburide; Hypera | 2018 |
Antiallodynic activity of leflunomide is partially inhibited by naltrexone and glibenclamide and associated with reduced production of TNF-α and CXCL-1.
Topics: Animals; Chemokine CXCL1; Glyburide; Hyperalgesia; Isoxazoles; Leflunomide; Male; Mice; Naltrexone; | 2018 |
Metformin antinociceptive effect in models of nociceptive and neuropathic pain is partially mediated by activation of opioidergic mechanisms.
Topics: Analgesics; Animals; Disease Models, Animal; Female; Glyburide; Hyperalgesia; Metformin; Mice; Naltr | 2019 |
Analysis of the mechanisms underlying the antinociceptive effect of epicatechin in diabetic rats.
Topics: Analgesics; Animals; Biphenyl Compounds; Catechin; Diabetes Mellitus, Experimental; Dose-Response Re | 2013 |
Phagocytic microglial phenotype induced by glibenclamide improves functional recovery but worsens hyperalgesia after spinal cord injury in adult rats.
Topics: Animals; Cells, Cultured; Female; Glyburide; Hyperalgesia; Locomotion; Microglia; Neuroprotective Ag | 2013 |
Role of ATP-sensitive potassium channels in modulating nociception in rat model of bone cancer pain.
Topics: Animals; Bone Neoplasms; Cell Line, Tumor; Disease Models, Animal; Female; Glyburide; Hyperalgesia; | 2014 |
Antinociceptive activities of the methanol extract of the bulbs of Dioscorea bulbifera L. var sativa in mice is dependent of NO-cGMP-ATP-sensitive-K(+) channel activation.
Topics: Animals; Cyclic GMP; Female; Freund's Adjuvant; Glyburide; Hyperalgesia; Inflammation; KATP Channels | 2010 |
Adenosine triphosphate-sensitive potassium channel blockers attenuate the antiallodynic effect of R-PIA in neuropathic rats.
Topics: 4-Aminopyridine; Adenosine; Adenosine Triphosphate; Animals; Glyburide; Humans; Hyperalgesia; Inject | 2011 |
N-palmitoyl-ethanolamine (PEA) induces peripheral antinociceptive effect by ATP-sensitive K+-channel activation.
Topics: Amides; Analgesics; Animals; Dequalinium; Dinoprostone; Disease Models, Animal; Dose-Response Relati | 2012 |
Mechanisms involved in the antinociception caused by compound MV8612 isolated from Mandevilla velutina in mice.
Topics: Analgesics; Animals; Apamin; Bradykinin; Capsaicin; Charybdotoxin; Formaldehyde; Glyburide; Glycosid | 2003 |
Diclofenac-induced peripheral antinociception is associated with ATP-sensitive K+ channels activation.
Topics: Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dinoprostone; Dose-Response | 2004 |
Riboflavin reduces hyperalgesia and inflammation but not tactile allodynia in the rat.
Topics: Analgesics; Animals; Carrageenan; Enzyme Inhibitors; Female; Glyburide; Hyperalgesia; Inflammation; | 2004 |
Study of the involvement of K+ channels in the peripheral antinociception of the kappa-opioid receptor agonist bremazocine.
Topics: 4-Aminopyridine; Analgesics; Animals; ATP-Binding Cassette Transporters; Benzomorphans; Charybdotoxi | 2004 |
Involvement of nitric oxide in the inhibition of bone cancer-induced hyperalgesia through the activation of peripheral opioid receptors in mice.
Topics: Analysis of Variance; Animals; Bone Neoplasms; Carbazoles; Dose-Response Relationship, Drug; Drug Ad | 2007 |
Dibutyryl-cyclic GMP induces peripheral antinociception via activation of ATP-sensitive K(+) channels in the rat PGE2-induced hyperalgesic paw.
Topics: 4-Aminopyridine; Adenosine Triphosphate; Analgesics; Animals; Apamin; Cesium; Charybdotoxin; Dibutyr | 2001 |