glyburide has been researched along with Akinetic-Rigid Variant of Huntington Disease in 2 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The R6/2 transgenic mouse model of Huntington's disease (HD) develops a progressive neurological phenotype that involves severe motor and cognitive dysfunctions." | 1.33 | Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents. ( Hunt, MJ; Morton, AJ, 2005) |
| "Brain samples from five patients with Huntington's disease were studied." | 1.29 | Sulfonylurea binding sites in normal human brain and in Parkinson's disease, progressive supranuclear palsy and Huntington's disease. ( Agid, Y; De Paermentier, F; Holemans, S; Javoy-Agid, F; Laterre, EC; Maloteaux, JM, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hunt, MJ | 1 |
| Morton, AJ | 1 |
| Holemans, S | 1 |
| Javoy-Agid, F | 1 |
| Agid, Y | 1 |
| De Paermentier, F | 1 |
| Laterre, EC | 1 |
| Maloteaux, JM | 1 |
2 other studies available for glyburide and Akinetic-Rigid Variant of Huntington Disease
| Article | Year |
|---|---|
Atypical diabetes associated with inclusion formation in the R6/2 mouse model of Huntington's disease is not improved by treatment with hypoglycaemic agents.
Topics: Administration, Oral; Animals; Behavior, Animal; Diabetes Mellitus; Disease Models, Animal; Exocytos | 2005 |
Sulfonylurea binding sites in normal human brain and in Parkinson's disease, progressive supranuclear palsy and Huntington's disease.
Topics: Adenosine Triphosphate; Aged; Aged, 80 and over; Animals; ATP-Binding Cassette Transporters; Brain C | 1994 |