Page last updated: 2024-10-28

glyburide and Acute Brain Injuries

glyburide has been researched along with Acute Brain Injuries in 15 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Research Excerpts

ExcerptRelevanceReference
"Glibenclamide reduced cerebral edema and mortality in a basic study of cerebral ischemia."1.91Glibenclamide reduces secondary brain injury in a SAH rat model by reducing brain swelling and modulating inflammatory response. ( Igarashi, T; Kajimoto, R; Moro, N; Oshima, H; Otani, N; Suma, T; Yoshino, A, 2023)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (13.33)18.2507
2000's4 (26.67)29.6817
2010's6 (40.00)24.3611
2020's3 (20.00)2.80

Authors

AuthorsStudies
Kajimoto, R1
Igarashi, T1
Moro, N1
Oshima, H1
Suma, T1
Otani, N1
Yoshino, A1
Wang, Z2
Zhang, S1
Du, J1
Lachance, BB1
Chen, S1
Polster, BM1
Jia, X2
Zusman, BE1
Wu, Y1
Kochanek, PM1
Vagni, VE1
Janesko-Feldman, K1
Gerzanich, V3
Simard, JM4
Karahalios, K1
Mihaljevic, S1
Raikwar, S1
Rani, A1
Rulney, J1
Desai, SM1
Catapano, J1
Jha, RM1
Yang, X1
Garg, K1
Singh, PM1
Khalili, H1
Derakhshan, N1
Ghaffarpasand, F1
Heydari, ST1
Ding, J1
Yuan, F1
Guo, JY1
Chen, H1
Tian, HL1
Zweckberger, K1
Hackenberg, K1
Jung, CS1
Hertle, DN1
Kiening, KL1
Unterberg, AW1
Sakowitz, OW1
Kilbourne, M1
Tsymbalyuk, O1
Tosun, C1
Caridi, J1
Ivanova, S1
Keledjian, K1
Bochicchio, G1
Patel, AD1
Geng, Z1
Chen, M1
Dong, Y1
Armstead, WM3
Vavilala, MS1
Golding, EM1
Robertson, CS1
Bryan, RM1

Other Studies

15 other studies available for glyburide and Acute Brain Injuries

ArticleYear
Glibenclamide reduces secondary brain injury in a SAH rat model by reducing brain swelling and modulating inflammatory response.
    Journal of neurosurgical sciences, 2023, Volume: 67, Issue:4

    Topics: Animals; Brain Edema; Brain Injuries; Brain Neoplasms; Cytokines; Endothelial Cells; Glyburide; Rats

2023
Neuroprotection of NSC Therapy is Superior to Glibenclamide in Cardiac Arrest-Induced Brain Injury via Neuroinflammation Regulation.
    Translational stroke research, 2023, Volume: 14, Issue:5

    Topics: Animals; Brain Injuries; Glucose; Glyburide; Heart Arrest; Humans; Microglia; Neural Stem Cells; Neu

2023
Precision Effects of Glibenclamide on MRI Endophenotypes in Clinically Relevant Murine Traumatic Brain Injury.
    Critical care medicine, 2023, 02-01, Volume: 51, Issue:2

    Topics: Animals; Bayes Theorem; Brain Contusion; Brain Edema; Brain Injuries; Brain Injuries, Traumatic; Dis

2023
Neuroprotection of Glibenclamide against Brain Injury after Cardiac Arrest via Modulation of NLRP3 Inflammasome.
    Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference, 2019, Volume: 2019

    Topics: Animals; Brain Injuries; Cardiopulmonary Resuscitation; Disease Models, Animal; Glyburide; Heart Arr

2019
Letter to the Editor Regarding "Effects of Oral Glibenclamide on Brain Contusion Volume and Functional Outcome of Patients with Moderate and Severe Traumatic Brain Injuries: A Randomized Double-Blind Placebo-Controlled Clinical Trial".
    World neurosurgery, 2017, Volume: 105

    Topics: Brain Contusion; Brain Injuries; Brain Injuries, Traumatic; Contusions; Double-Blind Method; Glyburi

2017
In Reply to the Letter to the Editor Regarding "Effects of Oral Glibenclamide on Brain Contusion Volume and Functional Outcome of Patients with Moderate and Severe Traumatic Brain Injuries: A Randomized Double-Blind Placebo-Controlled Clinical Trial".
    World neurosurgery, 2017, Volume: 105

    Topics: Brain Contusion; Brain Injuries; Brain Injuries, Traumatic; Contusions; Double-Blind Method; Glyburi

2017
Influence of glibenclamide on outcome in patients with type 2 diabetes and traumatic brain injury.
    Clinical neurology and neurosurgery, 2013, Volume: 115, Issue:10

    Topics: Adult; Age Factors; Aged; Blood Glucose; Brain Injuries; Diabetes Mellitus, Type 2; Female; Glasgow

2013
Glibenclamide reduces secondary brain damage after experimental traumatic brain injury.
    Neuroscience, 2014, Jul-11, Volume: 272

    Topics: Animals; Brain Edema; Brain Injuries; Disease Models, Animal; Electroencephalography; Glyburide; Int

2014
Key role of sulfonylurea receptor 1 in progressive secondary hemorrhage after brain contusion.
    Journal of neurotrauma, 2009, Volume: 26, Issue:12

    Topics: Animals; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Brain Hemorrhage, Traumatic;

2009
Glibenclamide reduces hippocampal injury and preserves rapid spatial learning in a model of traumatic brain injury.
    Journal of neuropathology and experimental neurology, 2010, Volume: 69, Issue:12

    Topics: Animals; Brain Injuries; Disease Models, Animal; Glyburide; Hippocampus; Maze Learning; Rats; Rats,

2010
Functional coupling between sulfonylurea receptor type 1 and a nonselective cation channel in reactive astrocytes from adult rat brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2003, Sep-17, Volume: 23, Issue:24

    Topics: Adenosine Triphosphate; Animals; Antibodies; Astrocytes; ATP-Binding Cassette Transporters; Binding,

2003
Adrenomedullin reduces gender-dependent loss of hypotensive cerebrovasodilation after newborn brain injury through activation of ATP-dependent K channels.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2007, Volume: 27, Issue:10

    Topics: Adenosine Triphosphate; Adrenomedullin; Animals; Animals, Newborn; Arteries; Brain Injuries; Female;

2007
Role of impaired cAMP and calcium-sensitive K+ channel function in altered cerebral hemodynamics following brain injury.
    Brain research, 1997, Sep-12, Volume: 768, Issue:1-2

    Topics: Animals; Brain; Brain Injuries; Calcium; Cyclic AMP; Disease Models, Animal; Female; Glyburide; Hemo

1997
Brain injury impairs prostaglandin cerebrovasodilation.
    Journal of neurotrauma, 1998, Volume: 15, Issue:9

    Topics: Animals; Animals, Newborn; Arterioles; Blood Gas Analysis; Brain Chemistry; Brain Injuries; Calcium

1998
L-arginine partially restores the diminished CO2 reactivity after mild controlled cortical impact injury in the adult rat.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2000, Volume: 20, Issue:5

    Topics: Animals; Arginine; Arterioles; Brain; Brain Injuries; Carbon Dioxide; Catalase; Free Radical Scaveng

2000