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glyburide and Acidosis

glyburide has been researched along with Acidosis in 23 studies

Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.

Acidosis: A pathologic condition of acid accumulation or depletion of base in the body. The two main types are RESPIRATORY ACIDOSIS and metabolic acidosis, due to metabolic acid build up.

Research Excerpts

ExcerptRelevanceReference
" However, block of voltage-gated K+ channels by 3 mmol/l 4-aminopyridine abolished acidosis-induced changes in K+ current amplitudes in both VSM cell types."3.70Intracellular acidosis differentially regulates KV channels in coronary and pulmonary vascular muscle. ( Berger, MG; Bonnet, P; Jackson, WF; Rusch, NJ; Vandier, C, 1998)
" There were 42 cases of metformin-associated lactic acidosis (MALA) with 18 deaths (43%); 40 of the MALA cases had documented contra-indications, especially renal impairment, and the remaining two cases were due to drug overdosage, one being a suicide."3.67Metformin and the sulphonylureas: the comparative risk. ( Campbell, IW, 1985)
"Metabolic acidosis is associated with various clinical situations including diabetes mellitus and renal diseases."1.33Acidosis-induced relaxation of human internal mammary artery is due to activation of ATP-sensitive potassium channels. ( Ghayur, MN; Gilani, AH; Rohra, DK; Sarfraz, K; Sharif, HM; Zubairi, HS, 2005)
" At the same time about 1/3 of these serious adverse drug reactions (ADR) was found to have been reported to the ADR-register."1.27Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden. ( Westerholm, B; Wiholm, BE, 1984)

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19906 (26.09)18.7374
1990's7 (30.43)18.2507
2000's8 (34.78)29.6817
2010's2 (8.70)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Subramaniam, G1
Achike, FI2
Mustafa, MR1
Yeo, JL1
Tan, BT1
Hsu, CY1
Fang, SY1
Chen, YZ1
Roan, JN1
Chang, SW1
Huang, CC1
Liu, YC1
Lam, CF1
Tsai, YC1
Shioiri, H1
Komaru, T1
Sato, K1
Takahashi, K1
Takeda, S1
Kanatsuka, H1
Watanabe, J1
Shirato, K1
Lindauer, U1
Vogt, J1
Schuh-Hofer, S1
Dreier, JP1
Dirnagl, U1
Heintz, A1
Koch, T1
Deussen, A1
Rohra, DK1
Sharif, HM1
Zubairi, HS1
Sarfraz, K1
Ghayur, MN1
Gilani, AH1
Wiholm, BE1
Westerholm, B1
Campbell, IW2
Duty, S1
Allen, DG1
Kinoshita, H1
Katusic, ZS1
Miura, K1
Kano, S1
Nakai, T1
Satoh, K1
Hoshi, K1
Ichihara, K1
Bethell, HW1
Vandenberg, JI1
Smith, GA1
Grace, AA1
Hayabuchi, Y1
Nakaya, Y1
Matsuoka, S1
Kuroda, Y1
Berger, MG1
Vandier, C1
Bonnet, P1
Jackson, WF1
Rusch, NJ1
Ishizaka, H1
Gudi, SR1
Frangos, JA1
Kuo, L1
Lobov, GI1
Kubyshkina, NA1
Legtenberg, RJ1
Houston, RJ1
Heerschap, A1
Oeseburg, B1
Smits, P1
Horiuchi, T1
Dietrich, HH1
Hongo, K1
Goto, T1
Dacey, RG1
Haslbeck, M1
Loubatières, A1
Ribes, G1
Blayac, JP1
Stowers, JM1

Reviews

2 reviews available for glyburide and Acidosis

ArticleYear
[New aspects of therapy with oral antidiabetic agents].
    Wiener medizinische Wochenschrift (1946), 1979, Dec-30, Volume: 199, Issue:24

    Topics: Acidosis; Biguanides; Blood Proteins; Chlorpropamide; Diabetes Mellitus; Diabetic Nephropathies; Dru

1979
Oral treatment in diabetes.
    Clinics in endocrinology and metabolism, 1972, Volume: 1, Issue:3

    Topics: Acetohexamide; Acidosis; Administration, Oral; Animals; Biguanides; Cardiovascular Diseases; Chlorpr

1972

Other Studies

21 other studies available for glyburide and Acidosis

ArticleYear
Effect of acidosis on the mechanism(s) of insulin-induced vasorelaxation in normal Wistar-Kyoto (WKY) rat aorta.
    Regulatory peptides, 2009, Jun-05, Volume: 155, Issue:1-3

    Topics: 4-Aminopyridine; Acidosis; Animals; Aorta; Barium Compounds; Chlorides; Endothelium, Vascular; Glybu

2009
Exploring the mechanism of endothelial involvement in acidosis-induced vasodilatation of aortic tissues from normal and diabetic rats.
    European journal of pharmacology, 2010, Sep-10, Volume: 642, Issue:1-3

    Topics: 4-Aminopyridine; Acidosis; Animals; Aorta; Barium Compounds; Chlorides; Diabetes Mellitus; Endotheli

2010
Cardiovascular protection of activating KATP channel during ischemia-reperfusion acidosis.
    Shock (Augusta, Ga.), 2012, Volume: 37, Issue:6

    Topics: Acidosis; Adamantane; Animals; Aorta, Abdominal; Calcium; Dose-Response Relationship, Drug; Glyburid

2012
Impact of hypercholesterolemia on acidosis-induced coronary microvascular dilation.
    Basic research in cardiology, 2003, Volume: 98, Issue:2

    Topics: Acidosis; Animals; Anti-Arrhythmia Agents; Arterioles; Coronary Vessels; Dilatation, Pathologic; Dis

2003
Cerebrovascular vasodilation to extraluminal acidosis occurs via combined activation of ATP-sensitive and Ca2+-activated potassium channels.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2003, Volume: 23, Issue:10

    Topics: Acidosis; Adenosine Triphosphate; Animals; Benzimidazoles; Cerebrovascular Circulation; Enzyme Inhib

2003
Intact nitric oxide production is obligatory for the sustained flow response during hypercapnic acidosis in guinea pig heart.
    Cardiovascular research, 2005, Apr-01, Volume: 66, Issue:1

    Topics: Acidosis; Animals; Coronary Circulation; Endothelium, Vascular; Female; Glyburide; Guinea Pigs; Hype

2005
Acidosis-induced relaxation of human internal mammary artery is due to activation of ATP-sensitive potassium channels.
    European journal of pharmacology, 2005, May-09, Volume: 514, Issue:2-3

    Topics: Acidosis; Adenosine Triphosphate; Calcium; Glyburide; Humans; Hydrogen-Ion Concentration; In Vitro T

2005
Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden.
    Acta medica Scandinavica. Supplementum, 1984, Volume: 683

    Topics: Acidosis; Aged; Anti-Infective Agents, Urinary; Biguanides; Congenital Abnormalities; Contraceptives

1984
Metformin and glibenclamide: comparative risks.
    British medical journal (Clinical research ed.), 1984, Aug-04, Volume: 289, Issue:6440

    Topics: Acidosis; Aged; Diabetes Mellitus, Type 2; Glyburide; Humans; Hypoglycemia; Lactates; Metformin; Ris

1984
The effects of glibenclamide on tetanic force and intracellular calcium in normal and fatigued mouse skeletal muscle.
    Experimental physiology, 1995, Volume: 80, Issue:4

    Topics: Acidosis; Adenosine Triphosphate; Animals; Benzopyrans; Calcium; Cromakalim; Electric Stimulation; G

1995
Role of potassium channels in relaxations of isolated canine basilar arteries to acidosis.
    Stroke, 1997, Volume: 28, Issue:2

    Topics: 4-Aminopyridine; Acidosis; Adenosine Triphosphate; Animals; ATP-Binding Cassette Transporters; Bariu

1997
Inhibitory effects of glibenclamide and pertussis toxin on the attenuation of ischemia-induced myocardial acidosis following ischemic preconditioning in dogs.
    Japanese circulation journal, 1997, Volume: 61, Issue:8

    Topics: Acetylcholine; Acidosis; Adenosine Triphosphate; Animals; Blood Glucose; Blood Pressure; Dogs; Femal

1997
Changes in ventricular repolarization during acidosis and low-flow ischemia.
    The American journal of physiology, 1998, Volume: 275, Issue:2

    Topics: Acidosis; Action Potentials; Adenosine Triphosphate; Animals; Decanoic Acids; Ferrets; Glyburide; He

1998
Effect of acidosis on Ca2+-activated K+ channels in cultured porcine coronary artery smooth muscle cells.
    Pflugers Archiv : European journal of physiology, 1998, Volume: 436, Issue:4

    Topics: Acidosis; Animals; Cells, Cultured; Chelating Agents; Coronary Vessels; Egtazic Acid; Glyburide; Hyp

1998
Intracellular acidosis differentially regulates KV channels in coronary and pulmonary vascular muscle.
    The American journal of physiology, 1998, Volume: 275, Issue:4

    Topics: 4-Aminopyridine; Acidosis; Ammonium Chloride; Animals; Cell Membrane; Coronary Vessels; Elapid Venom

1998
Coronary arteriolar dilation to acidosis: role of ATP-sensitive potassium channels and pertussis toxin-sensitive G proteins.
    Circulation, 1999, Feb-02, Volume: 99, Issue:4

    Topics: Acidosis; Adenosine Triphosphate; Animals; Arterioles; Coronary Vessels; Female; Glyburide; GTP-Bind

1999
Effect of acidosis on contractile function of mesenterial lymphatic vessels in bulls.
    Bulletin of experimental biology and medicine, 2001, Volume: 132, Issue:1

    Topics: Acidosis; Animals; Anti-Arrhythmia Agents; Barium Compounds; Cattle; Chlorides; Glyburide; Hydrogen-

2001
Glibenclamide attenuates ischemia-induced acidosis and loss of cardiac function in rats.
    European journal of pharmacology, 2002, Jan-02, Volume: 434, Issue:1-2

    Topics: Acidosis; Adenosine Triphosphate; Animals; Coronary Circulation; Glyburide; Glycolysis; Hydrogen-Ion

2002
Role of endothelial nitric oxide and smooth muscle potassium channels in cerebral arteriolar dilation in response to acidosis.
    Stroke, 2002, Volume: 33, Issue:3

    Topics: Acidosis; Amides; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arterioles; Cerebrovascular Circ

2002
Metformin and the sulphonylureas: the comparative risk.
    Hormone and metabolic research. Supplement series, 1985, Volume: 15

    Topics: Acidosis; Diabetes Mellitus, Type 2; Drug Interactions; Glyburide; Humans; Hypoglycemia; Metformin;

1985
[Exogenous and endogenous insulin inhibit hyperlactacidemia induced in dogs by administration of phenformin].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1973, Jan-29, Volume: 676, Issue:5

    Topics: Acidosis; Animals; Dogs; Glyburide; Hypoglycemic Agents; Insulin; Insulin Secretion; Lactates; Male;

1973