glyburide has been researched along with Abnormalities, Congenital in 6 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| " As with other oral hypoglycemics, the use of glyburide in pregnancy has been limited by fears of neonatal hypoglycemia following fetal exposure." | 8.84 | Safety of glyburide for gestational diabetes: a meta-analysis of pregnancy outcomes. ( Koren, G; Moretti, ME; Rezvani, M, 2008) |
| " As with other oral hypoglycemics, the use of glyburide in pregnancy has been limited by fears of neonatal hypoglycemia following fetal exposure." | 4.84 | Safety of glyburide for gestational diabetes: a meta-analysis of pregnancy outcomes. ( Koren, G; Moretti, ME; Rezvani, M, 2008) |
| "Women with gestational diabetes mellitus are rarely treated with a sulfonylurea drug, because of concern about teratogenicity and neonatal hypoglycemia." | 2.69 | A comparison of glyburide and insulin in women with gestational diabetes mellitus. ( Berkus, MD; Conway, DL; Gonzales, O; Langer, O; Xenakis, EM, 2000) |
| " At the same time about 1/3 of these serious adverse drug reactions (ADR) was found to have been reported to the ADR-register." | 1.27 | Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden. ( Westerholm, B; Wiholm, BE, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (16.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Omori, Y | 1 |
| Reece, EA | 1 |
| Moretti, ME | 1 |
| Rezvani, M | 1 |
| Koren, G | 1 |
| Wiholm, BE | 1 |
| Westerholm, B | 1 |
| Langer, O | 1 |
| Conway, DL | 1 |
| Berkus, MD | 1 |
| Xenakis, EM | 1 |
| Gonzales, O | 1 |
| Greene, MF | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Glyburide and Metformin for the Treatment of Gestational Diabetes Mellitus. A Systematic Review and Meta-analysis of Randomized Controlled Trials Comparing These Drugs Either vs Insulin or vs Each Other.[NCT01998113] | 2,509 participants (Actual) | Observational | 2013-03-31 | Completed | |||
| Non-inferiority Between Acarbose and Prandial Insulin for the Treatment of Gestational Diabetes Mellitus: a Randomized Multicenter and Prospective Trial. ACARB-GDM Study.[NCT03380546] | Phase 3 | 341 participants (Actual) | Interventional | 2018-07-04 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for glyburide and Abnormalities, Congenital
| Article | Year |
|---|---|
[Medical management of pregnant women with diabetes].
Topics: Blood Glucose; Body Weight; Congenital Abnormalities; Diabetic Nephropathies; Diabetic Retinopathy; | 2002 |
Safety of glyburide for gestational diabetes: a meta-analysis of pregnancy outcomes.
Topics: Congenital Abnormalities; Diabetes, Gestational; Female; Fetal Blood; Fetal Macrosomia; Glyburide; H | 2008 |
1 trial available for glyburide and Abnormalities, Congenital
| Article | Year |
|---|---|
A comparison of glyburide and insulin in women with gestational diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Congenital Abnormalities; Diabetes, Gestational; Female; Fetal Blo | 2000 |
A comparison of glyburide and insulin in women with gestational diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Congenital Abnormalities; Diabetes, Gestational; Female; Fetal Blo | 2000 |
A comparison of glyburide and insulin in women with gestational diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Congenital Abnormalities; Diabetes, Gestational; Female; Fetal Blo | 2000 |
A comparison of glyburide and insulin in women with gestational diabetes mellitus.
Topics: Adolescent; Adult; Blood Glucose; Congenital Abnormalities; Diabetes, Gestational; Female; Fetal Blo | 2000 |
3 other studies available for glyburide and Abnormalities, Congenital
| Article | Year |
|---|---|
Synopsis of the North American Diabetes in Pregnancy Study Group Conference in Little Rock, Arkansas, May 2003.
Topics: Blood Glucose; Caffeine; Cesarean Section; Congenital Abnormalities; Delivery, Obstetric; Diabetes, | 2004 |
Drug utilization and morbidity statistics for the evaluation of drug safety in Sweden.
Topics: Acidosis; Aged; Anti-Infective Agents, Urinary; Biguanides; Congenital Abnormalities; Contraceptives | 1984 |
Oral hypoglycemic drugs for gestational diabetes.
Topics: Blood Glucose; Congenital Abnormalities; Diabetes, Gestational; Female; Fetal Blood; Fetal Macrosomi | 2000 |