glyburide has been researched along with ADPKD in 2 studies
Glyburide: An antidiabetic sulfonylurea derivative with actions like those of chlorpropamide
glyburide : An N-sulfonylurea that is acetohexamide in which the acetyl group is replaced by a 2-(5-chloro-2-methoxybenzamido)ethyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cyst growth in ADPKD is driven by cell proliferation and Cl(-) and fluid secretion." | 1.31 | Sulfonylurea-sensitive K(+) transport is involved in Cl(-) secretion and cyst trowth by cultured ADPKD cells. ( Eppler, JW; Gover, T; Grantham, JJ; Maser, R; Sullivan, LP; Wallace, DP; Welling, PA; Yamaguchi, T, 2002) |
| "Primary cultures both of ADPKD epithelial cells and a mixed population of normal renal epithelial cells isolated from the cortex (HRCE cells) were used." | 1.31 | cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells. ( Guggino, WB; Hanaoka, K, 2000) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sullivan, LP | 1 |
| Wallace, DP | 1 |
| Gover, T | 1 |
| Welling, PA | 1 |
| Yamaguchi, T | 1 |
| Maser, R | 1 |
| Eppler, JW | 1 |
| Grantham, JJ | 1 |
| Hanaoka, K | 1 |
| Guggino, WB | 1 |
2 other studies available for glyburide and ADPKD
| Article | Year |
|---|---|
Sulfonylurea-sensitive K(+) transport is involved in Cl(-) secretion and cyst trowth by cultured ADPKD cells.
Topics: Barium; Cell Division; Cells, Cultured; Charybdotoxin; Chlorides; Disease Progression; Glyburide; Hu | 2002 |
cAMP regulates cell proliferation and cyst formation in autosomal polycystic kidney disease cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Cell Division; Cells, Cultured; Chloride Channels; | 2000 |